Microbiomics, the genomic study of a population of microbes, is a recent field propelled by the rapid evolution of high-throughput sequencing. Microbiomics facilitates the study of the diversity and the role of microorganisms in diverse habitats. The study of microbial communities associated with hosts has received attention by the recognition of the important role of microbes in host development, homeostasis and the pathophysiology of chronic diseases including type 2 diabetes or non-alcoholic fatty liver disease.
The Advanced Microbiomics group takes advantage of the accumulated know-how in the field of bacterial genome sequencing, microbial community profiling (structure and dynamics) and metagenomics of the PI and her team and the available high-throughput DNA sequencing and HPC infrastructures at CIBB to address the following research lines:
Collaboration with other research groups at the Metabolism, Aging and Disease research line allows to correlate genotype with phenotype, including investigating the regulation of host metabolism by bacterial metabolites.
Metafluidics: Advanced toolbox for rapid and cost-effective functional metagenomic screening - microbiology meets microfluidics. European Commission (2016-2020). PI: Conceição Egas.
GenomePT. Project for the development and implementation of research infrastructures within RNIE. 01/SAICT/2016. 2017-2019. PI: Conceição Egas.
Immunotargeting efflux systems for therapeutic modulation of multidrug resistant bacteria. FCT - Fundação para a Ciência e Tecnologia (2018-2021). PI: Ricardo Pires.
Interações nemátode da madeira do pinheiro-árvore hospedeira: à descoberta de alternativas sustentáveis para a gestão da doença da murchidão do Pinheiro. FCT - Fundação para a Ciência e Tecnologia (2018-2021). PI: Luis Fonseca.
Symbioreactor - Sustainable Production of Bioactive Metabolites from Microbial Symbionts of Marine Sponges and Corals. Fundo Azul (2020-2022) PI: Conceição Egas.