Publicações
Informação sobre artigos em revista, actualizada a 22-12-2024, a partir da plataforma CIÊNCIAVITAE.
Heterogeneous redox responses in NHDF cells primed to enhance mitochondrial bioenergetics
Sónia A. Pinho; Paulo J. Oliveira; Teresa Cunha-Oliveira, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2025. https://doi.org/10.1016/j.bbadis.2024.167495 . 10.1016/j.bbadis.2024.167495 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Best Practices for Data Management and Sharing in Experimental Biomedical Research
Cunha-Oliveira, T.; Ioannidis, John P.A.; Oliveira, Paulo J., Physiological Reviews. 2024. http://dx.doi.org/10.1152/physrev.00043.2023 . 10.1152/physrev.00043.2023 . in press Physiological Reviews
Mitochondria: A Promising Convergent Target for the Treatment of Amyotrophic Lateral Sclerosis
Teresa Cunha-Oliveira; Liliana Montezinho; Rui F. Simões; Marcelo Carvalho; Elisabete Ferreiro; Filomena S. G. Silva, Cells. 2024. https://doi.org/10.3390/cells13030248 . 10.3390/cells13030248 . Cells
Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate Model
Susana P. Pereira; Mariana S. Diniz; Ludgero C. Tavares; Teresa Cunha-Oliveira; Cun Li; Laura A. Cox; Mark J. Nijland; Peter W. Nathanielsz; Paulo J. Oliveira, International Journal of Molecular Sciences. 2023. https://doi.org/10.3390/ijms242015192 . 10.3390/ijms242015192 . International Journal of Molecular Sciences
Metabolic Priming as a Tool in Redox and Mitochondrial Theragnostics
Pinho, S.A.; Anjo, S.I.; Cunha-Oliveira, T., Antioxidants. 2023. https://www.mdpi.com/2076-3921/12/5/1072 . 10.3390/antiox12051072 . published Antioxidants
Integrative Profiling of Amyotrophic Lateral Sclerosis Lymphoblasts Identifies Unique Metabolic and Mitochondrial Disease Fingerprints
Cunha-Oliveira, T.; Carvalho, Marcelo; Sardão, V.; Ferreiro, Elisabete; Mena, D.; Francisco B Pereira ; Borges, Fernanda; Oliveira, P.J.; Silva, Filomena, Research Square. 2022. https://www.researchsquare.com/article/rs-1196454/v1 . 10.21203/rs.3.rs-1196454/v1 . under revision Research Square
Mitochondrial and metabolic remodeling in human skin fibroblasts in response to glucose availability
Pinho, Sónia A.; Costa, Cláudio F.; Deus, Cláudia M.; Pinho, Sonia L.C.; Miranda-Santos, Inês; Afonso, Gonçalo; Bagshaw, Olivia; et al, The FEBS Journal. 2022. http://dx.doi.org/10.1111/febs.16413 . 10.1111/febs.16413 . published The FEBS Journal
Redox profiles of amyotrophic lateral sclerosis lymphoblasts with or without known SOD1 mutations
Cunha-Oliveira, T.; Silva, Daniela Franco; Segura, Luis; Baldeiras, Inês; Marques, Ricardo; Rosenstock, Tatiana; Oliveira, Paulo J.; Silva, Filomena S. G., European Journal of Clinical Investigation. 9. 52. 2022. http://dx.doi.org/10.1111/eci.13798 . 10.1111/eci.13798 . published European Journal of Clinical Investigation
Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics
Rui F. Simões; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira, International Journal of Molecular Sciences. 3009 - 3009. 6. 23. 2022. https://doi.org/10.3390/ijms23063009 . 10.3390/ijms23063009 . International Journal of Molecular Sciences
Integrative Profiling of Amyotrophic Lateral Sclerosis Lymphoblasts Identifies Unique Metabolic and Mitochondrial Disease Fingerprints
Cunha-Oliveira, Teresa; Carvalho, Marcelo; Sardão, Vilma; Ferreiro, Elisabete; Mena, Débora; Pereira, Francisco B.; Borges, Fernanda; Oliveira, Paulo J.; Silva, Filomena S. G., Molecular Neurobiology. 6373 - 6396. 10. 59. 2022. http://dx.doi.org/10.1007/s12035-022-02980-7 . 10.1007/s12035-022-02980-7 . published Molecular Neurobiology
NRF2 and Mitochondrial Function in Cancer and Cancer Stem Cells
Panieri, Emiliano; Pinho, Sónia A.; Afonso, Gonçalo J. M.; Oliveira, Paulo J.; Cunha-Oliveira, T.; Saso, Luciano, Cells. 15. 11. 2022. http://dx.doi.org/10.3390/cells11152401 . 10.3390/cells11152401 . published Cells
Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems
Amorim, Ricardo; Simões, Inês C.M.; Teixeira, José; Cagide, Fernando; Potes, Yaiza; Soares, Pedro; Carvalho, Adriana; et al, Redox Biology. 55. 2022. http://dx.doi.org/10.1016/j.redox.2022.102400 . 10.1016/j.redox.2022.102400 . published Redox Biology
MPV17 mutations are associated with a quiescent energetic metabolic profile
Jacinto, Sandra; Guerreiro. Patrícia; Machado de Oliveira, Rita; Cunha-Oliveira, T.; Santos, Maria João; Grazina, Manuela; Rego, Ana Cristina; Outeiro, Tiago, Frontiers in Cellular Neuroscience. 2021. https://www.frontiersin.org/articles/10.3389/fncel.2021.641264/abstract . published Frontiers in Cellular Neuroscience
Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine
Rui F. Simões; Rute Pino; Maurício Moreira-Soares; Jaromira Kovarova; Jiri Neuzil; Rui Travasso; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira, The FASEB Journal. 12. 35. 2021. https://doi.org/10.1096/fj.202100899R . 10.1096/fj.202100899R . The FASEB Journal
A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients
Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Teixeira, José; Simões, Rui F.; Cagide, Fernando; Benfeito, Sofia; et al, Redox Biology. 2021. http://dx.doi.org/10.1016/j.redox.2021.102037 . 10.1016/j.redox.2021.102037 . published Redox Biology
Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction
Pereira, Susana P.; Tavares, Ludgero C.; Duarte, Ana I.; Baldeiras, Inês; Cunha-Oliveira, Teresa; Martins, João D.; Santos, Maria S.; et al, Clinical Science. 1103 - 1126. 9. 135. 2021. http://dx.doi.org/10.1042/cs20201339 . 10.1042/cs20201339 . published Clinical Science
Mitochondrial and metabolic remodeling in human skin fibroblasts in response to glucose availability
Costa, C. F.; Pinho, S.A.; Pinho, S. L.; Miranda-Santos, I.; Bagshaw, O.; Stuart, J.; Oliveira, P.J.; # Cunha-Oliveira, T., BioRxiv. 2021. https://www.biorxiv.org/content/10.1101/2021.02.24.432508v1 . 10.1101/2021.02.24.432508 . published BioRxiv
Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research
Simões, Rui F.; Ferrão, Rafaela; Silva, Margarida R.; Pinho, Sonia L. C.; Ferreira, Lino; Oliveira, Paulo J.; # Cunha-Oliveira, T., Food and Chemical Toxicology. 2021. https://doi.org/10.1016/j.fct.2021.111967 . 10.1016/j.fct.2021.111967 . published Food and Chemical Toxicology
Mitochondrial remodeling in human skin fibroblasts from sporadic male Parkinson's disease patients uncovers metabolic and mitochondrial bioenergetic defects
Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Pereira, Francisco B.; Raimundo, Nuno; Oliveira, Paulo J., Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 3. 1866. 2020. http://dx.doi.org/10.1016/j.bbadis.2019.165615 . 10.1016/j.bbadis.2019.165615 . published Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention
Cunha-Oliveira, Teresa; Montezinho, Liliana; Mendes, Catarina; Firuzi, Omidreza; Saso, Luciano; Oliveira, Paulo J.; Silva, Filomena S. G., Oxidative Medicine and Cellular Longevity. 1 - 29. 2020. 2020. http://dx.doi.org/10.1155/2020/5021694 . 10.1155/2020/5021694 . published Oxidative Medicine and Cellular Longevity
Maternal obesity in sheep impairs foetal hepatic mitochondrial respiratory chain capacity
Serafim, Teresa L.; * Cunha-Oliveira, Teresa; Deus, Claudia M.; Sardão, Vilma A.; Cardoso, Ines M.; Yang, Shanshan; Odhiambo, John F.; et al, European Journal of Clinical Investigation. 2. 51. 2020. http://dx.doi.org/10.1111/eci.13375 . 10.1111/eci.13375 . published European Journal of Clinical Investigation
Impact of Carcinogenic Chromium on the Cellular Response to Proteotoxic Stress
Ferreira, Leonardo M. R.; Cunha-Oliveira, Teresa; Sobral, Margarida C.; Abreu, Patrícia L.; Alpoim, Maria Carmen; Urbano, Ana M., International Journal of Molecular Sciences. 19. 20. 2019. http://dx.doi.org/10.3390/ijms20194901 . 10.3390/ijms20194901 . published International Journal of Molecular Sciences
Doxorubicin persistently rewires cardiac circadian homeostasis in mice
Ferreira, Luciana L.; Cervantes, Marlene; Froufe, Hugo J. C.; Egas, Conceição; Cunha-Oliveira, Teresa; Sassone-Corsi, Paolo; Oliveira, Paulo J., Archives of Toxicology. 2019. http://dx.doi.org/10.1007/s00204-019-02626-z . 10.1007/s00204-019-02626-z . published Archives of Toxicology
Intracellular and Intercellular Mitochondrial Dynamics in Parkinson's Disease
Valdinocci, Dario; Simões, Rui F.; Kovarova, Jaromira; Cunha-Oliveira, Teresa; Neuzil, Jiri; Pountney, Dean L., Frontiers in Neuroscience. 13. 2019. http://dx.doi.org/10.3389/fnins.2019.00930 . 10.3389/fnins.2019.00930 . Frontiers in Neuroscience
Single nanomolar doxorubicin exposure triggers compensatory mitochondrial responses in H9c2 cardiomyoblasts
Ferreira, Luciana L.; Cunha-Oliveira, Teresa; Veloso, Caroline D.; Costa, Cláudio F.; Wallace, Kendall B.; Oliveira, Paulo J., Food and Chemical Toxicology. 450 - 461. 124. 2019. http://dx.doi.org/10.1016/j.fct.2018.12.017 . 10.1016/j.fct.2018.12.017 . published Food and Chemical Toxicology
Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells
Bajzikova, Martina; Kovarova, Jaromira; Coelho, Ana R.; Boukalova, Stepana; Oh, Sehyun; Rohlenova, Katerina; Svec, David; et al, Cell Metabolism. 399 - 416.e10. 2. 29. 2019. http://dx.doi.org/10.1016/j.cmet.2018.10.014 . 10.1016/j.cmet.2018.10.014 . published Cell Metabolism
Hexavalent chromium, a lung carcinogen, confers resistance to thermal stress and interferes with heat shock protein expression in human bronchial epithelial cells
Abreu, Patrícia L.; Cunha-Oliveira, Teresa; Ferreira, Leonardo M. R.; Urbano, Ana M., BioMetals. 477 - 487. 4. 31. 2018. http://dx.doi.org/10.1007/s10534-018-0093-7 . 10.1007/s10534-018-0093-7 . published BioMetals
Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes
# Teresa Cunha-Oliveira; Luciana L. Ferreira; Ana Raquel Coelho; Cláudia M. Deus; Paulo J. Oliveira, Toxicology and Applied Pharmacology. 1 - 13. 348. 2018. https://doi.org/10.1016/j.taap.2018.04.009 . 10.1016/j.taap.2018.04.009 . published Toxicology and Applied Pharmacology
Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative Capacity
Pereira, Susana P; Deus, Cláudia M; Serafim, Teresa L; Cunha-Oliveira, Teresa; Oliveira, Paulo J, Toxicological Sciences. 191 - 204. 1. 164. 2018. http://dx.doi.org/10.1093/toxsci/kfy068 . 10.1093/toxsci/kfy068 . published Toxicological Sciences
Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease
Naia, Luana; * Cunha-Oliveira, Teresa; Rodrigues, Joana; Rosenstock, Tatiana R.; Oliveira, Ana; Ribeiro, Márcio; Carmo, Catarina; et al, The Journal of Neuroscience. 2776 - 2794. 10. 37. 2017. http://dx.doi.org/10.1523/jneurosci.2006-14.2016 . 10.1523/JNEUROSCI.2006-14.2016 . published The Journal of Neuroscience
Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts
Coelho, Ana R.; Martins, Tatiana R.; Couto, Renata; Deus, Cláudia; Pereira, Cláudia V.; Simões, Rui F.; Rizvanov, Albert A.; et al, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2904 - 2923. 11. 1863. 2017. http://dx.doi.org/10.1016/j.bbadis.2017.07.030 . 10.1016/j.bbadis.2017.07.030 . published Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Altered mitochondrial epigenetics associated with subchronic doxorubicin cardiotoxicity
Ferreira, André; * Cunha-Oliveira, Teresa; Simões, Rui F.; Carvalho, Filipa S.; Burgeiro, Ana; Nordgren, Kendra; Wallace, Kendall B.; Oliveira, Paulo J., Toxicology. 63 - 73. 390. 2017. http://dx.doi.org/10.1016/j.tox.2017.08.011 . 10.1016/j.tox.2017.08.011 . published Toxicology
Involvement of mitochondrial dysfunction in nefazodone-induced hepatotoxicity
Silva, Ana Marta; Barbosa, Inês A.; Seabra, Cátia; Beltrão, Nuno; Santos, Raquel; Vega-Naredo, Ignacio; Oliveira, Paulo J.; # Cunha-Oliveira, Teresa, Food and Chemical Toxicology. 148 - 158. 1. 94. 2016. http://dx.doi.org/10.1016/j.fct.2016.06.001 . 10.1016/j.fct.2016.06.001 . published Food and Chemical Toxicology
Ketogenic diets: from cancer to mitochondrial diseases and beyond
Branco, Ana F.; Ferreira, André; Simões, Rui F.; Magalhães-Novais, Sílvia; Zehowski, Cheryl; Cope, Elisabeth; Silva, Ana Marta; et al, European Journal of Clinical Investigation. 285 - 298. 3. 46. 2016. http://dx.doi.org/10.1111/eci.12591 . 10.1111/eci.12591 . published European Journal of Clinical Investigation
Role of mtDNA-related mitoepigenetic phenomena in cancer
Ferreira, André; Serafim, Teresa L; Sardão, Vilma A; # Cunha-Oliveira, Teresa, European Journal of Clinical Investigation. 44 - 49. S1. 45. 2015. http://dx.doi.org/10.1111/eci.12359 . 10.1111/eci.12359 . published European Journal of Clinical Investigation
Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human Lymphoblasts
Naia, Luana; Ferreira, I. Luísa; Cunha-Oliveira, Teresa; Duarte, Ana I.; Ribeiro, Márcio; Rosenstock, Tatiana R.; Laço, Mário N.; et al, Molecular Neurobiology. 331 - 348. 1. 51. 2015. http://dx.doi.org/10.1007/s12035-014-8735-4 . 10.1007/s12035-014-8735-4 . published Molecular Neurobiology
ß-adrenergic over-stimulation and cardio-myocyte apoptosis: two receptors, one organelle, two fates?
Branco, Ana F; Moreira, Ana C; Cunha-Oliveira, Teresa; Couto, Renata; Sardao, Vilma A; Rizvanov, Albert A; Palotas, Andras; et al, Current Drug Targets. 956 - 964. 10. 15. 2014. http://dx.doi.org/10.2174/1389450115666140902124230 . 10.2174/1389450115666140902124230 . published Current Drug Targets
Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts
Moreira, Ana C; Branco, Ana F; Sampaio, Susana F; Cunha-Oliveira, Teresa; Martins, Tatiana R; Holy, Jon; Oliveira, Paulo J; et al, Biochimica et Biophysica Acta-Molecular Basis of Disease. 2468 - 2478. 12. 1842. 2014. http://hdl.handle.net/10316/41109 . 10.1016/j.bbadis.2014.09.015 . published Biochimica et Biophysica Acta-Molecular Basis of Disease
Oxidative Stress and Drugs of Abuse: An Update
# Cunha-Oliveira, Teresa; Rego, A. Cristina; Oliveira, Catarina R., Mini-Reviews in Organic Chemistry. 321 - 334. 4. 10. 2013. http://dx.doi.org/10.2174/1570193X113106660026 . 10.2174/1570193X113106660026 . published Mini-Reviews in Organic Chemistry
Acute effects of cocaine, morphine and their combination on bioenergetic function and susceptibility to oxidative stress of rat liver mitochondria
# Cunha-Oliveira, Teresa; Silva, Lisbeth; Silva, Ana Maria; Moreno, António J.; Oliveira, Catarina R.; Santos, Maria S., Life Sciences. 1157 - 1164. 24-26. 92. 2013. http://dx.doi.org/10.1016/j.lfs.2013.04.016 . 10.1016/j.lfs.2013.04.016 . published Life Sciences
Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition
Bernardo, Telma C.; Cunha-Oliveira, Teresa; Serafim, Teresa L.; Holy, Jon; Krasutsky, Dmytro; Kolomitsyna, Oksana; Krasutsky, Pavel; Moreno, António M.; Oliveira, Paulo J., Bioorganic & Medicinal Chemistry. 7239 - 7249. 23. 21. 2013. http://dx.doi.org/10.1016/j.bmc.2013.09.066 . 10.1016/j.bmc.2013.09.066 . published Bioorganic & Medicinal Chemistry
Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse
Perfeito, Rita; * Cunha-Oliveira, Teresa; Rego, Ana Cristina, Free Radical Biology and Medicine. 186 - 201. 62. 2013. http://dx.doi.org/10.1016/j.freeradbiomed.2013.05.042 . 10.1016/j.freeradbiomed.2013.05.042 . published Free Radical Biology and Medicine
Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria
# Cunha-Oliveira, Teresa; Silva, Lisbeth; Silva, Ana Maria; Moreno, António J.; Oliveira, Catarina R.; Santos, Maria S., Toxicology Letters. 298 - 306. 3. 219. 2013. http://dx.doi.org/10.1016/j.toxlet.2013.03.025 . 10.1016/j.toxlet.2013.03.025 . published Toxicology Letters
Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells
Ribeiro, Márcio; Rosenstock, Tatiana R.; Cunha-Oliveira, Teresa; Ferreira, Ildete L.; Oliveira, Catarina R.; Rego, A. Cristina, Free Radical Biology and Medicine. 1857 - 1867. 10. 53. 2012. http://dx.doi.org/10.1016/j.freeradbiomed.2012.09.004 . 10.1016/j.freeradbiomed.2012.09.004 . published Free Radical Biology and Medicine
Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice
Pereira, Frederico C.; Cunha-Oliveira, Teresa; Viana, Sofia D.; Travassos, Ana S.; Nunes, Sara; Silva, Carlos; Prediger, Rui Daniel; et al, Neurotoxicology and Teratology. 522 - 529. 5. 34. 2012. http://dx.doi.org/10.1016/j.ntt.2012.07.005 . 10.1016/j.ntt.2012.07.005 . published Neurotoxicology and Teratology
Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease - Resemblance to the effect of amphetamine drugs of abuse
Perfeito, R.; * Cunha-Oliveira, T.; Rego, A.C., Free Radical Biology and Medicine. 1791 - 1806. 9. 53. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867397192&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2012.08.569 . Free Radical Biology and Medicine
Bioenergetic dysfunction in Huntington's disease human cybrids
Ferreira, I. Luisa; * Cunha-Oliveira, Teresa; Nascimento, Maria V.; Ribeiro, Márcio; Proença, M. Teresa; Januário, Cristina; Oliveira, Catarina R.; Rego, A. Cristina, Experimental Neurology. 127 - 134. 1. 231. 2011. http://dx.doi.org/10.1016/j.expneurol.2011.05.024 . 10.1016/j.expneurol.2011.05.024 . published Experimental Neurology
Neurotoxicity of heroin-cocaine combinations in rat cortical neurons
Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R., Toxicology. 11 - 17. 1. 276. 2010. http://dx.doi.org/10.1016/j.tox.2010.06.009 . 10.1016/j.tox.2010.06.009 . published Toxicology
Dysregulation of CREB Activation and Histone Acetylation in 3-Nitropropionic Acid-Treated Cortical Neurons: Prevention by BDNF and NGF
Almeida, Sandra; Cunha-Oliveira, Teresa; Laço, Mário; Oliveira, Catarina R.; Rego, A. Cristina, Neurotoxicity Research. 399 - 405. 4. 17. 2009. http://dx.doi.org/10.1007/s12640-009-9116-z . 10.1007/s12640-009-9116-z . published Neurotoxicity Research
BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons
Almeida, S.; Laço, M.; Cunha-Oliveira, T.; Oliveira, C.R.; Rego, A.C., Neurobiology of Disease. 448 - 456. 3. 35. 2009. http://dx.doi.org/10.1016/j.nbd.2009.06.006 . 10.1016/j.nbd.2009.06.006 . published Neurobiology of Disease
Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs
Cunha-Oliveira, T.; Rego, A.C.; Oliveira, C.R.; Cunha-Oliveira, Teresa; Rego, Ana Cristina; Oliveira, Catarina R., Brain Research Reviews. 192 - 208. 1. 58. 2008. http://dx.doi.org/10.1016/j.brainresrev.2008.03.002 . 10.1016/j.brainresrev.2008.03.002 . Brain Research Reviews
Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons
Cunha-Oliveira, T.; Rego, A.C.; Garrido, J.; Borges, F.; Macedo, T.; Oliveira, C.R., Journal of Neurochemistry. 543 - 554. 2. 101. 2007. http://dx.doi.org/10.1111/j.1471-4159.2006.04406.x . 10.1111/j.1471-4159.2006.04406.x . Journal of Neurochemistry
Adaptation to oxidative stress in the chronic effects of cocaine and amphetamine
Cunha-Oliveira, T; Rego, AC; Macedo, T; Oliveira, CR, Free Radical Research. S22 - S22. 41. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000252296300068&KeyUID=WOS:000252296300068 . Free Radical Research
Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide
Cunha-Oliveira, Teresa; Rego, A. Cristina; Morgadinho, Maria Teresa; Macedo, Tice; Oliveira, Catarina Resende, Toxicology. 54 - 62. 1. 217. 2006. http://dx.doi.org/10.1016/j.tox.2005.08.022 . 10.1016/j.tox.2005.08.022 . Toxicology
Expression of NR1/NR2B N-methyl-D-aspartate receptors enhances heroin toxicity in HEK293 cells
Domingues, A.; * Oliveira, T.C.; Laço, M.L.N.; Macedo, T.R.A.; Oliveira, C.R.; Rego, A.C., Annals of the New York Academy of Sciences. 458 - 465. 1074. 2006. http://dx.doi.org/10.1196/annals.1369.046 . 10.1196/annals.1369.046 . published Annals of the New York Academy of Sciences
Mitochondrial dysfunction and caspase activation in rat cortical neurons treated with cocaine or amphetamine
Cunha-Oliveira, T.; Rego, A.C.; Cardoso, S.M.; Borges, F.; Swerdlow, R.H.; Macedo, T.; de Oliveira, C.R., Brain Research. 44 - 54. 1. 1089. 2006. http://dx.doi.org/10.1016/j.brainres.2006.03.061 . 10.1016/j.brainres.2006.03.061 . published Brain Research
Synthesis and cytotoxic profile of 3,4-methylenedioxymethamphetamine ("ecstasy") and its metabolites on undifferentiated PC12 cells: A putative structure-toxicity relationship
Milhazes, N.; Cunha-Oliveira, T.; Martins, P.; Garrido, J.; Oliveira, C.; Rego, A.C.; Borges, F., Chemical Research in Toxicology. 1294 - 1304. 10. 19. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750209029&partnerID=MN8TOARS . 10.1021/tx060123i . Chemical Research in Toxicology
Efeito crónico da heroína e do peróxido de hidrogénio em células PC12
Cunha-Oliveira, Teresa; Rego, A Cristina; Morgadinho, M Teresa; Macedo, Tice R; Oliveira, Catarina R, Coimbra Médica V. 21 - 29. 1. 2. 2006. http://hdl.handle.net/10316/18520 . published Coimbra Médica V
Drugs of abuse induce apoptotic features in PC12 cells
Cunha-Oliveira, T.; Rego, A.C.; Macedo, T.; Oliveira, C.R., Annals of the New York Academy of Sciences. 667 - 670. 1. 1010. 2003. http://dx.doi.org/10.1196/annals.1299.121 . 10.1196/annals.1299.121 . published Annals of the New York Academy of Sciences
Toxic effects of opioid and stimulant drugs on undifferentiated PC12 cells
# Cunha-Oliveira, T.; Rego, A.C.; Morgadinho, M.T.; Macedo, T.R.A.; Oliveira, C.R., Annals of the New York Academy of Sciences. 487 - 496. 965. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036290212&partnerID=MN8TOARS . 10.1111/j.1749-6632.2002.tb04190.x . published Annals of the New York Academy of Sciences
5 60 de 60 Publicações
Todos os projectos
Informação da exclusiva responsabilidade do investigador 22-12-2024 , a partir da plataforma CIÊNCIAVITAE.
2023/03/01
EXCELScIOR: EXCELlent Science with Impact, Open and Reliable
101087416
Researcher
Universidade de Coimbra
Financiadores: Horizon Europe
2023/05
PAS GRAS - De-risking metabolic, environmental and behavioral determinants of obesity in children, adolescents and young adults
101080329
Researcher
Financiadores: European Commission
2022/01/15 - 2025/01/14
Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral Sclerosis
PTDC/BTM-ORG/0055/2021
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2022/01/01 - 2023/06/30
Role of mitochondrial-thiol homeostasis in neurodegeneration: implication for amyotrophic lateral sclerosis
EXPL/BTM-TEC/1407/2021
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2022 - 2023/06/30
Mitochondria as potential drivers of sex-specific microglia dysfunctional remodelling and anxiety caused by prenatal stress
EXPL/MED-NEU/1002/2021
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2021/03/29 - 2024/03/28
SYNAPTIC VESICLE MATURATION AND ITS RELEVANCE FOR NEURODEGENERATION
PTDC/MED-NEU/8030/2020
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2021/01/01 - 2023/12/31
Organelle-targeted Radiocomplexes for Auger Therapy of Cancer
PTDC/MED-QUI/1554/2020
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2019/02/01 - 2025/01/31
MitoProfiling- Mitochondrial Health Profiling. Applications in Toxicology and Personalized Medicine
DL 57/2016/CP1448/CT0016
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2018/09/01 - 2019
Brain protection by Evolocumab in individuals at high risk for cardiovascular disease: from bench to bedside
PEPITA2018
Researcher
Universidade de Coimbra Faculdade de Medicina
Financiadores: Universidade de Coimbra Faculdade de Medicina
2018/05/01 - 2021/04/30
Development of Novel Mitochondria-Targeted Antioxidants for Improving SOD1-Familial Amyotrophic Lateral Sclerosis Phenotype
PTDC/MED-FAR/29391/2017
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade do Porto
Financiadores: Fundação para a Ciência e a Tecnologia
2018/07/06 - 2021/12/05
Development and validation of innovative screening methods for mitochondrial health modulators
PTDC/BTM-SAL/29297/2017
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2015/01/01 - 2017
An Epigenetic Engineering Approach to Reverse the Parkinson Disease Cell State
Montepio_CNC
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: Fundação Montepio
2015/10 - 2018/09
EXERCISING THE FUTURE: Voluntary Exercise During Gestational Diabetes as a Means to Improve Mitochondrial Function in the Offspring
grant.Provided by PTCRIS: 139707
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: Fundacao para a Ciencia e a Tecnologia
2015/10 - 2018/09
MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidant Delivery to Mitochondria
grant.Provided by PTCRIS: 141059
Researcher
Financiadores: Fundacao para a Ciencia e a Tecnologia
2014/03/01 - 2015/09/30
Stemcell based platforms for regenerative and therapeutic medicine
CENTRO-07-ST24-FEDER-002008
Post-doc Fellow
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: European Regional Development Fund
2013/12/01 - 2014/02/28
Role of mitochondrial p66Shc in drug-induced mitochondrial toxicity memory
grant.Provided by PTCRIS: 117912
Post-doc Fellow
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: Fundacao para a Ciencia e a Tecnologia
2013/05 - 2016/04
Pathophysiology of Persistent Doxorubicin Cardiotoxicity: a Mitochondrial-Epigenetics Link
PTDC/DTP-FTO/1180/2012
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: Fundacao para a Ciencia e a Tecnologia
2012/09/01 - 2013
Alpha-synuclein modifications in peripheral blood lymphocytes from sporadic and familial Parkinson's disease patients
PDCR02
Researcher
Universidade de Coimbra Faculdade de Medicina
Financiadores: Universidade de Coimbra Faculdade de Medicina
2008/09 - 2010/08
Relationship Between Body Weight and the Development of Heroin Addiction: Role of Insulin and Leptin Hypothalamic Signalling Pathways
grant.Provided by PTCRIS: 126115
Principal investigator
Financiadores: Instituto de Investigação Interdisciplinar, Universidade de Coimbra
2005/07 - 2008/06
Biochemical and Behavioural Study of Opioid-Cocaine Interactions
grant.Provided by PTCRIS: 58330
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: Fundacao para a Ciencia e a Tecnologia
2004/09/01 - 2005
Contribution of different subunits of the NMDA receptor to heroin cytotoxicity
GAI/06/2004
Researcher
Universidade de Coimbra Faculdade de Medicina
Financiadores: Universidade de Coimbra Faculdade de Medicina
5 21 de 21 projetos
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