Publications
Information about journal articles, updated at 24-11-2024, from platform CIÊNCIAVITAE.
In Vitro Characterization of Reversine-Treated Gingival Fibroblasts and Their Safety Evaluation after In Vivo Transplantation
Marto, Carlos Miguel; Laranjo, Mafalda; Gonçalves AC; Paula, Anabela; Jorge, Joana; Caetano-Oliveira, Rui; Sousa, Maria Inês; et al, Pharmaceutics. 2. 16. 2024. http://dx.doi.org/10.3390/pharmaceutics16020207 . 10.3390/pharmaceutics16020207 . published Pharmaceutics
Practical Management of Disease-related Manifestations and Drug Toxicities in Patients with Multiple Myeloma
Geraldes, C; Roque, A; Sarmento-Ribeiro, AB; Neves, M; Ionita, A; Gerivaz, R; Tomé, A; et al, Front. Oncol. (Sec. Hematologic Malignancies). 14. 2024. published Front. Oncol. (Sec. Hematologic Malignancies)
Platelet Membrane Proteins as Pain Biomarkers in Patients with Severe Dementia
Ribeiro, Hugo; Alves, Raquel; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Teixeira-Veríssimo, Manuel; Dourado, Marília; Andrade, José Paulo, Biomedicines. 2. 11. 2023. http://dx.doi.org/10.3390/biomedicines11020380 . 10.3390/biomedicines11020380 . Biomedicines
Zinc: From Biological Functions to Therapeutic Potential
Costa, Maria Inês; Sarmento-Ribeiro, Ana Bela; Gonçalves, Ana Cristina, International Journal of Molecular Sciences. 5. 24. 2023. http://dx.doi.org/10.3390/ijms24054822 . 10.3390/ijms24054822 . International Journal of Molecular Sciences
AZD-7648, a DNA-PK Inhibitor, Induces DNA Damage, Apoptosis, and Cell Cycle Arrest in Chronic and Acute Myeloid Leukemia Cells
Beatriz Lapa; Maria Inês Costa; Diana Figueiredo; Joana Jorge; Raquel Alves; Ana Raquel Monteiro; Beatriz Serambeque; et al, International Journal of Molecular Sciences. 2023. https://www.mdpi.com/1422-0067/24/20/15331 . 10.3390/ijms242015331 . International Journal of Molecular Sciences
Alvespimycin Inhibits Heat Shock Protein 90 and Overcomes Imatinib Resistance in Chronic Myeloid Leukemia Cell Lines
Alves, Raquel; Santos, Diogo; Jorge, Joana; Gonçalves, Ana Cristina; Catarino, Steve; Girão, Henrique; Melo, Joana Barbosa; Sarmento-Ribeiro, AB, Molecules. 3. 28. 2023. http://dx.doi.org/10.3390/molecules28031210 . 10.3390/molecules28031210 . Molecules
Recomendações do Grupo Português do Mieloma Múltiplo para Tratamento do Mieloma Múltiplo
João, Cristina; Bergantim, Rui; Santos, Joana; Afonso, Celina; Bernardo, Paulo; Coelho, Henrique; Costa, Carlos; et al, Acta Médica Portuguesa. 517 - 526. 7-8. 36. 2023. http://dx.doi.org/10.20344/amp.19037 . 10.20344/amp.19037 . published Acta Médica Portuguesa
Parthenolide Induces ROS-Mediated Apoptosis in Lymphoid Malignancies
Jorge, Joana; Neves, Joana; Alves, Raquel; Geraldes, Catarina; Gonçalves, Ana Cristina; Sarmento-Ribeiro, AB, International Journal of Molecular Sciences. 11. 24. 2023. http://dx.doi.org/10.3390/ijms24119167 . 10.3390/ijms24119167 . International Journal of Molecular Sciences
Monocytes in the Characterization of Pain in Palliative Patients with Severe Dementia—A Pilot Study
Ribeiro, Hugo; Alves, Raquel; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, AB; Teixeira-Veríssimo, Manuel; Andrade, José Paulo; Dourado, Marília, International Journal of Molecular Sciences. 13. 24. 2023. http://dx.doi.org/10.3390/ijms241310723 . 10.3390/ijms241310723 . International Journal of Molecular Sciences
Zinc Prevents DNA Damage in Normal Cells but Shows Genotoxic and Cytotoxic Effects in Acute Myeloid Leukemia Cells
Costa, Maria Inês; Lapa, Beatriz Santos; Jorge, Joana; Alves, Raquel; Carreira, Isabel Marques; Sarmento-Ribeiro, Ana Bela; Gonçalves, Ana Cristina, International Journal of Molecular Sciences. 5. 23. 2022. http://dx.doi.org/10.3390/ijms23052567 . 10.3390/ijms23052567 . International Journal of Molecular Sciences
Cold Atmospheric Plasma Apoptotic and Oxidative Effects on MCF7 and HCC1806 Human Breast Cancer Cells
Almeida-Ferreira, Catarina; Silva-Teixeira, Rafael; Gonçalves, Ana Cristina; Marto, Carlos Miguel; Sarmento-Ribeiro, Ana Bela; Caramelo, Francisco; Botelho, Maria Filomena; Laranjo, Mafalda, International Journal of Molecular Sciences. 3. 23. 2022. http://dx.doi.org/10.3390/ijms23031698 . 10.3390/ijms23031698 . International Journal of Molecular Sciences
Antitumor Effect of Brusatol in Acute Lymphoblastic Leukemia Models Is Triggered by Reactive Oxygen Species Accumulation
Jorge, Joana; Magalhães, Nisa; Alves, Raquel; Lapa, Beatriz; Gonçalves, Ana Cristina; Sarmento-Ribeiro, AB, Biomedicines. 9. 10. 2022. http://dx.doi.org/10.3390/biomedicines10092207 . 10.3390/biomedicines10092207 . Biomedicines
Genetic Variants of ABC and SLC Transporter Genes and Chronic Myeloid Leukaemia: Impact on Susceptibility and Prognosis
Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Marques, Gilberto; Ribeiro, André B.; Tenreiro, Rita; Coucelo, Margarida; et al, International Journal of Molecular Sciences. 17. 23. 2022. http://dx.doi.org/10.3390/ijms23179815 . 10.3390/ijms23179815 . International Journal of Molecular Sciences
Apoptosis and (in) Pain—Potential Clinical Implications
Ribeiro, Hugo; Sarmento-Ribeiro, AB; Andrade, José Paulo; Dourado, Marília, Biomedicines. 6. 10. 2022. http://dx.doi.org/10.3390/biomedicines10061255 . 10.3390/biomedicines10061255 . Biomedicines
Combination of Elacridar with Imatinib Modulates Resistance Associated with Drug Efflux Transporters in Chronic Myeloid Leukemia
Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Almeida, António M.; Sarmento-Ribeiro, AB, Biomedicines. 5. 10. 2022. http://dx.doi.org/10.3390/biomedicines10051158 . 10.3390/biomedicines10051158 . Biomedicines
Liquid Biopsies: Applications for Cancer Diagnosis and Monitoring
Martins, Ivana; Ribeiro, Ilda Patrícia; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Melo, Joana Barbosa; Carreira, Isabel Marques, Genes. 3. 12. 2021. http://dx.doi.org/10.3390/genes12030349 . 10.3390/genes12030349 . published Genes
A Combined Antitumor Strategy Mediated by a New Targeted Nanosystem to Hepatocellular Carcinoma
Farinha, Dina; Migawa, Michael; Sarmento-Ribeiro, Ana Bela; Faneca, Henrique, International Journal of Nanomedicine. 3385 - 3405. Volume 16. 2021. http://dx.doi.org/10.2147/ijn.s302288 . 10.2147/ijn.s302288 . published International Journal of Nanomedicine
Genomic characterisation of multiple myeloma: study of a Portuguese cohort
Couto Oliveira, Alexandra; Ribeiro, Ilda Patrícia; Pires, Luís Miguel; Gonçalves, Ana Cristina; Paiva, Artur; Geraldes, Catarina; Roque, Adriana; et al, Journal of Clinical Pathology. jclinpath - 2020. 2021. http://dx.doi.org/10.1136/jclinpath-2020-207204 . 10.1136/jclinpath-2020-207204 . published Journal of Clinical Pathology
Plasma activated media and direct exposition can selectively ablate retinoblastoma cells
Silva-Teixeira, Rafael; Laranjo, Mafalda; Lopes, Beatriz; Almeida-Ferreira, Catarina; Gonçalves, Ana Cristina; Rodrigues, Tiago; Matafome, Paulo; et al, Free Radical Biology and Medicine. 302 - 313. 171. 2021. http://dx.doi.org/10.1016/j.freeradbiomed.2021.05.027 . 10.1016/j.freeradbiomed.2021.05.027 . in press Free Radical Biology and Medicine
Oxidative Stress Parameters Can Predict the Response to Erythropoiesis-Stimulating Agents in Myelodysplastic Syndrome Patients
Gonçalves, Ana Cristina; Alves, Raquel; Baldeiras, Inês; Jorge, Joana; Marques, Bárbara; Paiva, Artur; Oliveiros, Bárbara; et al, Frontiers in Cell and Developmental Biology. 9. 2021. http://dx.doi.org/10.3389/fcell.2021.701328 . 10.3389/fcell.2021.701328 . accepted Frontiers in Cell and Developmental Biology
Can peripheral blood provide good DNA methylation biomarkers in myelodysplastic syndrome?
Jorge, Joana; Gonçalves, Ana Cristina; Cortesão, Emília; Pires, Ana Cláudia; Alves, Raquel; Geraldes, Catarina; Pereira, Amélia; et al, Journal of Molecular and Clinical Medicine. 1. 4. 2021. http://dx.doi.org/10.31083/j.jmcm.2021.01.015 . 10.31083/j.jmcm.2021.01.015 . published Journal of Molecular and Clinical Medicine
Bone marrow follicular-like T cells in monoclonal gammopathies
Silva, Ana; Silva, Sandra; Silva, Isabel; Santos, Susana; Laranjeira, Paula; Geraldes, Catarina; Silva, Helena; et al, Cytometry Part B: Clinical Cytometry. 70 - 72. 1. 102. 2021. http://dx.doi.org/10.1002/cyto.b.22029 . 10.1002/cyto.b.22029 . Cytometry Part B: Clinical Cytometry
Accessing the Cytotoxicity and Cell Response to Biomaterials
Paula, Anabela Baptista; Laranjo, Mafalda; Coelho, Ana Sofia; Abrantes, Ana Margarida; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Ferreira, Manuel Marques; et al, Journal of Visualized Experiments. 173. 2021. http://dx.doi.org/10.3791/61512 . 10.3791/61512 . Journal of Visualized Experiments
The Hydropathy Index of the HCDR3 Region of the B-Cell Receptor Identifies Two Subgroups of IGHV-Mutated Chronic Lymphocytic Leukemia Patients With Distinct Outcome
Rodríguez-Caballero, Arancha; Fuentes Herrero, Blanca; Oliva Ariza, Guillermo; Criado, Ignacio; Alcoceba, Miguel; Prieto, Carlos; Pérez Caro, María; et al, Frontiers in Oncology. 11. 2021. http://dx.doi.org/10.3389/fonc.2021.723722 . 10.3389/fonc.2021.723722 . Frontiers in Oncology
Hypoxia as a driver of resistance to immunotherapy
Kopecka, Joanna; Salaroglio, Iris C.; Perez-Ruiz, Elizabeth; Sarmento-Ribeiro, Ana Bela; Saponara, Simona; De Las Rivas, Javier; Riganti, Chiara, Drug Resistance Updates. 59. 2021. http://dx.doi.org/10.1016/j.drup.2021.100787 . 10.1016/j.drup.2021.100787 . Drug Resistance Updates
Impact of cancer metabolism on therapy resistance – Clinical implications
Gonçalves, Ana Cristina; Richiardone, Elena; Jorge, Joana; Polónia, Bárbara; Xavier, Cristina P.R.; Salaroglio, Iris Chiara; Riganti, Chiara; et al, Drug Resistance Updates. 59. 2021. http://dx.doi.org/10.1016/j.drup.2021.100797 . 10.1016/j.drup.2021.100797 . Drug Resistance Updates
DNA Methylation Is Correlated with Oxidative Stress in Myelodysplastic Syndrome—Relevance as Complementary Prognostic Biomarkers
Gonçalves, Ana Cristina; Alves, Raquel; Baldeiras, Inês; Marques, Bárbara; Oliveiros, Bárbara; Pereira, Amélia; Nascimento Costa, José Manuel; et al, Cancers. 13. 13. 2021. http://dx.doi.org/10.3390/cancers13133138 . 10.3390/cancers13133138 . Cancers
Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia—From Molecular Mechanisms to Clinical Relevance
Alves, Raquel; Gonçalves, Ana Cristina; Rutella, Sergio; Almeida, António M.; De Las Rivas, Javier; Trougakos, Ioannis P.; Sarmento Ribeiro, Ana Bela, Cancers. 19. 13. 2021. http://dx.doi.org/10.3390/cancers13194820 . 10.3390/cancers13194820 . Cancers
Genomic characterisation of multiple myeloma: study of a Portuguese cohort
Couto Oliveira, Alexandra; Ribeiro, Ilda Patrícia; Pires, Luís Miguel; Gonçalves, Ana Cristina; Paiva, Artur; Geraldes, Catarina; Roque, Adriana; et al, Journal of Clinical Pathology. 422 - 425. 6. 75. 2021. http://dx.doi.org/10.1136/jclinpath-2020-207204 . 10.1136/jclinpath-2020-207204 . Journal of Clinical Pathology
Bone marrow follicular-like T cells in monoclonal gammopathies
Silva, Ana; Silva, Sandra; Silva, Isabel; Santos, Susana; Laranjeira, Paula; Geraldes, Catarina; Silva, Helena; et al, Cytometry Part B: Clinical Cytometry. 70 - 72. 1. 102. 2021. http://dx.doi.org/10.1002/cyto.b.22029 . 10.1002/cyto.b.22029 . Cytometry Part B: Clinical Cytometry
Effects of Adper™ Scotchbond™ 1 XT, Clearfil™ SE Bond 2 and Scotchbond™ Universal in Odontoblasts
Miguel Cardoso; Ana Coelho; Carlos Miguel Marto; Ana Cristina Gonçalves; Anabela Paula; Ana Bela Sarmento Ribeiro; Manuel Marques Ferreira; et al, Materials. 6435 - 6435. 21. 14. 2021. https://doi.org/10.3390/ma14216435 . 10.3390/ma14216435 . Materials
Flow cytometry and targeted immune transcriptomics identify distinct profiles in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitors with or without interferon-a
Alves, Raquel; McArdle, Stephanie E. B.; Vadakekolathu, Jayakumar; Gonçalves, Ana Cristina; Freitas-Tavares, Paulo; Pereira, Amélia; Almeida, Antonio M.; Sarmento-Ribeiro, Ana Bela; Rutella, Sergio, Journal of Translational Medicine. 1. 18. 2020. http://dx.doi.org/10.1186/s12967-019-02194-x . 10.1186/s12967-019-02194-x . published Journal of Translational Medicine
Cytotoxic Effects of Zoom® Whitening Product in Human Fibroblasts
Marto, Carlos Miguel; Laranjo, Mafalda; Paula, Anabela; Coelho, Ana Sofia; Abrantes, Ana Margarida; Casalta-Lopes, João; Gonçalves, Ana Cristina; et al, Materials. 7. 13. 2020. http://dx.doi.org/10.3390/ma13071491 . 10.3390/ma13071491 . Materials
GuttaFlow® Bioseal Cytotoxicity Assessment: In Vitro Study
Ferreira, Inês; Laranjo, Mafalda; Marto, Carlos Miguel; Casalta-Lopes, João; Serambeque, Beatriz; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; et al, Molecules. 18. 25. 2020. http://dx.doi.org/10.3390/molecules25184297 . 10.3390/molecules25184297 . published Molecules
Acute myeloid leukemia sensitivity to metabolic inhibitors: glycolysis showed to be a better therapeutic target
Lapa, Beatriz; Gonçalves, Ana Cristina; Jorge, Joana; Alves, Raquel; Pires, Ana Salomé; Abrantes, Ana Margarida; Coucelo, Margarida; et al, Medical Oncology. 8. 37. 2020. http://dx.doi.org/10.1007/s12032-020-01394-6 . 10.1007/s12032-020-01394-6 . published Medical Oncology
Platinum(II) ring-fused chlorins as efficient theranostic agents: Dyes for tumor-imaging and photodynamic therapy of cancer
Laranjo, Mafalda; Aguiar, Márcia Campos; Pereira, Nelson A.M.; Brites, Gonçalo; Nascimento, Bruno F.O.; Brito, Ana F.; Casalta-Lopes, João; et al, European Journal of Medicinal Chemistry. 200. 2020. http://dx.doi.org/10.1016/j.ejmech.2020.112468 . 10.1016/j.ejmech.2020.112468 . published European Journal of Medicinal Chemistry
miR-29b and retinoic acid co-delivery: a promising tool to induce a synergistic antitumoral effect in non-small cell lung cancer cells
Magalhães, Mariana; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Carvalho, Rui; Figueiras, Ana; Santos, Ana Cláudia; Veiga, Francisco, Drug Delivery and Translational Research. 1367 - 1380. 5. 10. 2020. http://dx.doi.org/10.1007/s13346-020-00768-7 . 10.1007/s13346-020-00768-7 . published Drug Delivery and Translational Research
Iodine-131 metabolic radiotherapy leads to cell death and genomic alterations through NIS overexpression on cholangiocarcinoma
Brito, Ana; Abrantes, Ana; Teixo, Ricardo; Pires, Ana; Ribeiro, Ana; Ferreira, Rafael; Fernandes, Alexandra; et al, International Journal of Oncology. 2020. http://dx.doi.org/10.3892/ijo.2020.4957 . 10.3892/ijo.2020.4957 . published International Journal of Oncology
Cancer immunotherapy resistance based on immune checkpoints inhibitors: Targets, biomarkers, and remedies
Pérez-Ruiz, Elisabeth; Melero, Ignacio; Kopecka, Joanna; Sarmento-Ribeiro, Ana Bela; García-Aranda, Marilina; De Las Rivas, Javier, Drug Resistance Updates. 53. 2020. http://dx.doi.org/10.1016/j.drup.2020.100718 . 10.1016/j.drup.2020.100718 . published Drug Resistance Updates
Synthetic Calcium Phosphate Ceramics as a Potential Treatment for Bisphosphonate-Related Osteonecrosis of the Jaw
Paulo, Siri; Laranjo, Mafalda; Abrantes, Ana M.; Casalta-Lopes, João; Santos, Kathleen; Gonçalves, Ana C.; Paula, Anabela Baptista; et al, Materials. 11. 12. 2019. http://dx.doi.org/10.3390/ma12111840 . 10.3390/ma12111840 . published Materials
MicroRNA signature refine response prediction in CML
Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Marques, Gilberto; Luís, Dino; Ribeiro, André B.; Freitas-Tavares, Paulo; et al, Scientific Reports. 1. 9. 2019. http://dx.doi.org/10.1038/s41598-019-46132-9 . 10.1038/s41598-019-46132-9 . published Scientific Reports
Everolimus in combination with Imatinib overcomes resistance in Chronic myeloid leukaemia
Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Alves, Joana; Alves da Silva, António; Freitas-Tavares, Paulo; Nascimento Costa, José M.; Almeida, António M.; Sarmento-Ribeiro, Ana B., Medical Oncology. 3. 36. 2019. http://dx.doi.org/10.1007/s12032-019-1253-5 . 10.1007/s12032-019-1253-5 . published Medical Oncology
CD43 and CD49d from the B-Cell Chronic Lymphoproliferative Disorders Diagnostic Panel Are Useful to Detect Erythroid Dysplasia
Oliveira, Melissa; Laranjeira, Paula; Fortuna, Manuela; Bártolo, Rui; Ribeiro, André; Santos, Mónica; Cortesão, Emília; et al, Cytometry Part B: Clinical Cytometry. 417 - 425. 5. 96. 2019. http://dx.doi.org/10.1002/cyto.b.21792 . 10.1002/cyto.b.21792 . published Cytometry Part B: Clinical Cytometry
Apoptosis induction and cell cycle arrest of pladienolide B in erythroleukemia cell lines
Jorge, Joana; Petronilho, Sara; Alves, Raquel; Coucelo, Margarida; Gonçalves, Ana Cristina; Nascimento Costa, José Manuel; Sarmento-Ribeiro, Ana Bela, Investigational New Drugs. 369 - 377. 2. 38. 2019. http://dx.doi.org/10.1007/s10637-019-00796-2 . 10.1007/s10637-019-00796-2 . published Investigational New Drugs
Cellular and molecular mechanisms of glioblastoma malignancy: Implications in resistance and therapeutic strategies
Balça-Silva, Joana; Matias, Diana; Carmo, Anália do; Sarmento-Ribeiro, Ana Bela; Lopes, Maria Celeste; Moura-Neto, Vivaldo, Seminars in Cancer Biology. 130 - 141. 58. 2019. http://dx.doi.org/10.1016/j.semcancer.2018.09.007 . 10.1016/j.semcancer.2018.09.007 . published Seminars in Cancer Biology
The multi-factorial nature of clinical multidrug resistance in cancer
Assaraf, Yehuda G.; Brozovic, Anamaria; Gonçalves, Ana Cristina; Jurkovicova, Dana; Line, Aija; Machuqueiro, Miguel; Saponara, Simona; et al, Drug Resistance Updates. 46. 2019. http://dx.doi.org/10.1016/j.drup.2019.100645 . 10.1016/j.drup.2019.100645 . published Drug Resistance Updates
The emergence of drug resistance to targeted cancer therapies: Clinical evidence
Sarmento-Ribeiro, Ana Bela; Scorilas, Andreas; Gonçalves, Ana Cristina; Efferth, Thomas; Trougakos, Ioannis P., Drug Resistance Updates. 47. 2019. http://dx.doi.org/10.1016/j.drup.2019.100646 . 10.1016/j.drup.2019.100646 . published Drug Resistance Updates
Biodentine™ Boosts, WhiteProRoot®MTA Increases and Life® Suppresses Odontoblast Activity
Paula, Anabela; Laranjo, Mafalda; Marto, Carlos Miguel; Abrantes, Ana Margarida; Casalta-Lopes, João; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; et al, Materials. 7. 12. 2019. http://dx.doi.org/10.3390/ma12071184 . 10.3390/ma12071184 . published Materials
Multiple myeloma in elderly patients—a Portuguese multicentric real-life study
João, Cristina; Bergantim, Rui; Neves, Manuel; Chacim, Sérgio; Afonso, Celina; Barradas, João; Bernardo, Manuela; et al, Annals of Hematology. 1689 - 1701. 7. 98. 2019. http://dx.doi.org/10.1007/s00277-019-03640-y . 10.1007/s00277-019-03640-y . published Annals of Hematology
Nucleolin is expressed in patient-derived samples and glioblastoma cells, enabling improved intracellular drug delivery and cytotoxicity
Balça-Silva, Joana; do Carmo, Anália; Tão, Hermínio; Rebelo, Olinda; Barbosa, Marcos; Moura-Neto, Vivaldo; Sarmento-Ribeiro, Ana Bela; Lopes, Maria Celeste; Moreira, João Nuno, Experimental Cell Research. 68 - 77. 1. 370. 2018. http://dx.doi.org/10.1016/j.yexcr.2018.06.005 . 10.1016/j.yexcr.2018.06.005 . published Experimental Cell Research
Venous thromboembolism risk associated with ABO, F11 and FGG loci
Manco, Licínio; Silva, Catarina; Fidalgo, Teresa; Martinho, Patrícia; Sarmento, Ana B.; Ribeiro, M. Letícia, Blood Coagulation & Fibrinolysis. 528 - 532. 6. 29. 2018. http://dx.doi.org/10.1097/mbc.0000000000000753 . 10.1097/mbc.0000000000000753 . published Blood Coagulation & Fibrinolysis
Quantification and phenotypic characterization of peripheral blood Vd1¿+¿T cells in chronic lymphocytic leukemia and monoclonal B cell lymphocytosis
Simões, Catarina; Silva, Isabel; Carvalho, Anabela; Silva, Sandra; Santos, Susana; Marques, Gilberto; Ribeiro, André; et al, Cytometry Part B: Clinical Cytometry. 164 - 168. 2. 96. 2018. http://dx.doi.org/10.1002/cyto.b.21645 . 10.1002/cyto.b.21645 . published Cytometry Part B: Clinical Cytometry
Clonal shifts in MDS – from SF3B1 to EZH2
Barbosa Ribeiro, André; Coucelo, Margarida; Tenreiro, Rita; Simões, Ana Teresa; Marques, Gilberto; Ribeiro, Letícia; Cortesão, Emília; Sarmento-Ribeiro, Ana Bela, Leukemia & Lymphoma. 2994 - 2997. 12. 59. 2018. http://dx.doi.org/10.1080/10428194.2018.1443452 . 10.1080/10428194.2018.1443452 . published Leukemia & Lymphoma
Epithelial-mesenchymal transition and microRNAs: Challenges and future perspectives in oral cancer
Domingues, Cátia Sofia da Costa; Serambeque, Beatriz Prazeres; Laranjo Cândido, Mafalda Sofia; Marto, Carlos Miguel Machado; Veiga, Francisco José de Baptista; Sarmento Antunes Cruz Ribeiro, Ana Bela; Figueiras, Ana Rita Ramalho; Botelho, Maria Filomena Roque; Dourado, Marília de Assunção Rodrigues Ferre, Head & Neck. 2304 - 2313. 10. 40. 2018. http://dx.doi.org/10.1002/hed.25381 . 10.1002/hed.25381 . published Head & Neck
Advances on photodynamic therapy of melanoma through novel ring-fused 5,15-diphenylchlorins
Pereira, Nelson A.M.; Laranjo, Mafalda; Pina, João; Oliveira, Andreia S.R.; Ferreira, João Dias; Sánchez-Sánchez, Carles; Casalta-Lopes, João; et al, European Journal of Medicinal Chemistry. 395 - 408. 146. 2018. http://dx.doi.org/10.1016/j.ejmech.2017.12.093 . 10.1016/j.ejmech.2017.12.093 . published European Journal of Medicinal Chemistry
TISSULAR GROWTH FACTORS PROFILE AFTER TEDUGLUTIDE ADMINISTRATION ON AN ANIMAL MODEL OF INTESTINAL ANASTOMOSIS; PERFIL TISULAR DE FACTORES DE CRECIMIENTO POST-ADMINISTRACIÓN DE TEDUGLUTIDE EN UN MODELO ANIMAL DE ANASTOMOSIS INTESTINAL
Costa, Beatriz Pinto; Gonçalves, Ana Cristina; Abrantes, Ana Margarida; Alves, Raquel; Matafome, Paulo; Seiça, Raquel; Sarmento-Ribeiro, Ana Bela; Botelho, Maria Filomena; Castro-Sousa, Francisco, Nutrición Hospitalaria. 2018. http://dx.doi.org/10.20960/nh.1326 . 10.20960/nh.1326 . published Nutrición Hospitalaria
Butyrate, a dietary fiber derivative that improves irinotecan effect in colon cancer cells
Encarnação, João Crispim; Pires, Ana Salomé; Amaral, Renata Alexandra; Gonçalves, Telmo José; Laranjo, Mafalda; Casalta-Lopes, João Eduardo; Gonçalves, Ana Cristina; et al, The Journal of Nutritional Biochemistry. 183 - 192. 56. 2018. http://dx.doi.org/10.1016/j.jnutbio.2018.02.018 . 10.1016/j.jnutbio.2018.02.018 . published The Journal of Nutritional Biochemistry
Ascorbic Acid Chemosensitizes Colorectal Cancer Cells and Synergistically Inhibits Tumor Growth
Pires, Ana S.; Marques, Cláudia R.; Encarnação, João C.; Abrantes, Ana M.; Marques, Inês A.; Laranjo, Mafalda; Oliveira, Rui; et al, Frontiers in Physiology. 9. 2018. http://dx.doi.org/10.3389/fphys.2018.00911 . 10.3389/fphys.2018.00911 . published Frontiers in Physiology
Effects of resistance exercise on endothelial progenitor cell mobilization in women
Ribeiro, Fernando; Ribeiro, Ilda P.; Gonçalves, Ana C.; Alves, Alberto J.; Melo, Elsa; Fernandes, Raquel; Costa, Rui; et al, Scientific Reports. 1. 7. 2017. http://dx.doi.org/10.1038/s41598-017-18156-6 . 10.1038/s41598-017-18156-6 . published Scientific Reports
Teduglutide effects on gene regulation of fibrogenesis on an animal model of intestinal anastomosis
Costa, Beatriz P.; Gonçalves, Ana C.; Abrantes, Ana M.; Matafome, Paulo; Seiça, Raquel; Sarmento-Ribeiro, Ana B.; Botelho, Maria Filomena; Castro-Sousa, Francisco, Journal of Surgical Research. 87 - 98. 216. 2017. http://dx.doi.org/10.1016/j.jss.2017.04.022 . 10.1016/j.jss.2017.04.022 . published Journal of Surgical Research
Intestinal Epithelial Stem Cells: Distinct Behavior After Surgical Injury and Teduglutide Administration
Costa, Beatriz P.; Gonçalves, Ana C.; Abrantes, Ana M.; Alves, Raquel; Matafome, Paulo; Seiça, Raquel; Sarmento-Ribeiro, Ana B.; Botelho, M. Filomena; Castro-Sousa, Francisco, Journal of Investigative Surgery. 243 - 252. 3. 31. 2017. http://dx.doi.org/10.1080/08941939.2017.1294217 . 10.1080/08941939.2017.1294217 . published Journal of Investigative Surgery
Intestinal inflammatory and redox responses to the perioperative administration of teduglutide in rats
Costa, Beatriz Pinto da; Gonçalves, Ana Cristina; Abrantes, Ana Margarida; Matafome, Paulo; Seiça, Raquel; Sarmento-Ribeiro, Ana Bela; Botelho, Maria Filomena; Castro-Sousa, Francisco, Acta Cirurgica Brasileira. 648 - 661. 8. 32. 2017. http://dx.doi.org/10.1590/s0102-865020170080000007 . 10.1590/s0102-865020170080000007 . published Acta Cirurgica Brasileira
Effects of teduglutide on histological parameters of intestinal anastomotic healing
Costa, Beatriz P.; Cipriano, Maria A.; Gonçalves, Ana C.; Abrantes, Ana M.; Matafome, Paulo; Seiça, Raquel; Sarmento-Ribeiro, Ana B.; Botelho, M. Filomena; Castro-Sousa, Francisco, European Surgery. 218 - 227. 5. 49. 2017. http://dx.doi.org/10.1007/s10353-017-0478-9 . 10.1007/s10353-017-0478-9 . published European Surgery
Glioblastoma entities express subtle differences in molecular composition and response to treatment
Balça-Silva, Joana; Matias, Diana; Do Carmo, Anália; Dubois, Luiz Gustavo; Gonçalves, Ana Cristina; Girão, Henrique; Silva Canedo, Nathalie Henriques; et al, Oncology Reports. 1341 - 1352. 3. 38. 2017. http://dx.doi.org/10.3892/or.2017.5799 . 10.3892/or.2017.5799 . published Oncology Reports
The Expression of Connexins and SOX2 Reflects the Plasticity of Glioma Stem-Like Cells
Balça-Silva, Joana; Matias, Diana; Dubois, Luiz Gustavo; Carneiro, Brenno; do Carmo, Anália; Girão, Henrique; Ferreira, Fernanda; et al, Translational Oncology. 555 - 569. 4. 10. 2017. http://dx.doi.org/10.1016/j.tranon.2017.04.005 . 10.1016/j.tranon.2017.04.005 . published Translational Oncology
Dual treatment with shikonin and temozolomide reduces glioblastoma tumor growth, migration and glial-to-mesenchymal transition
Matias, Diana; Balça-Silva, Joana; Dubois, Luiz Gustavo; Pontes, Bruno; Ferrer, Valéria Pereira; Rosário, Luciane; do Carmo, Anália; et al, Cellular Oncology. 247 - 261. 3. 40. 2017. http://dx.doi.org/10.1007/s13402-017-0320-1 . 10.1007/s13402-017-0320-1 . published Cellular Oncology
Single Shot Irradiation and Molecular Effects on a Diffuse Large B Cell Lymphoma Cell Line
Mendes, Fernando; Domingues, Cátia; Schugk, Susann; Abrantes, Ana Margarida; Gonçalves, Ana Cristina; Sales, Tiago; Teixo, Ricardo; et al, Journal of Cancer Research and Treatment. 9 - 16. 1. 4. 2016. published Journal of Cancer Research and Treatment
Aberrant p15, p16, p53, and DAPK Gene Methylation in Myelomagenesis: Clinical and Prognostic Implications
Geraldes, Catarina; Gonçalves, Ana Cristina; Cortesão, Emília; Pereira, Marta Isabel; Roque, Adriana; Paiva, Artur; Ribeiro, Letícia; Nascimento-Costa, José Manuel; Sarmento-Ribeiro, Ana Bela, Clinical Lymphoma Myeloma and Leukemia. 713 - 720.e2. 12. 16. 2016. http://dx.doi.org/10.1016/j.clml.2016.08.016 . 10.1016/j.clml.2016.08.016 . published Clinical Lymphoma Myeloma and Leukemia
Impact of splenic artery ligation after major hepatectomy on liver function, regeneration and viability
Carrapita, Jorge; Abrantes, Ana Margarida; Campelos, Sofia; Gonçalves, Ana Cristina; Cardoso, Dulce; Sarmento-Ribeiro, Ana Bela; Rocha, Clara; et al, Scientific Reports. 1. 6. 2016. http://dx.doi.org/10.1038/srep34731 . 10.1038/srep34731 . published Scientific Reports
The role of immune system exhaustion on cancer cell escape and anti-tumor immune induction after irradiation
Mendes, Fernando; Domingues, Cátia; Rodrigues-Santos, Paulo; Abrantes, Ana Margarida; Gonçalves, Ana Cristina; Estrela, Jéssica; Encarnação, João; et al, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 168 - 175. 2. 1865. 2016. http://dx.doi.org/10.1016/j.bbcan.2016.02.002 . 10.1016/j.bbcan.2016.02.002 . published Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Ascorbic acid and colon cancer: an oxidative stimulus to cell death depending on cell profile
Pires, Ana Salomé; Marques, Cláudia Raquel; Encarnação, João Carlos; Abrantes, Ana Margarida; Mamede, Ana Catarina; Laranjo, Mafalda; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Botelho, Maria Filomena, European Journal of Cell Biology. 208 - 218. 6-7. 95. 2016. http://dx.doi.org/10.1016/j.ejcb.2016.04.001 . 10.1016/j.ejcb.2016.04.001 . published European Journal of Cell Biology
Hyperresistinemia and metabolic dysregulation: a risky crosstalk in obese breast cancer
Crisóstomo, Joana; Matafome, Paulo; Santos-Silva, Daniela; Gomes, Ana L.; Gomes, Manuel; Patrício, Miguel; Letra, Liliana; et al, Endocrine. 433 - 442. 2. 53. 2016. http://dx.doi.org/10.1007/s12020-016-0893-x . 10.1007/s12020-016-0893-x . published Endocrine
Genetic variants involved in oxidative stress, base excision repair, DNA methylation, and folate metabolism pathways influence myeloid neoplasias susceptibility and prognosis
Gonçalves, Ana Cristina; Alves, Raquel; Baldeiras, Inês; Cortesão, Emília; Carda, José Pedro; Branco, Claudia C.; Oliveiros, Bárbara; et al, Molecular Carcinogenesis. 130 - 148. 1. 56. 2016. http://dx.doi.org/10.1002/mc.22478 . 10.1002/mc.22478 . published Molecular Carcinogenesis
New Approach for Treatment of Primary Liver Tumors: The Role of Quercetin
Brito, Ana Filipa; Ribeiro, Marina; Abrantes, Ana Margarida; Mamede, Ana Catarina; Laranjo, Mafalda; Casalta-Lopes, João Eduardo; Gonçalves, Ana Cristina; et al, Nutrition and Cancer. 250 - 266. 2. 68. 2016. http://dx.doi.org/10.1080/01635581.2016.1145245 . 10.1080/01635581.2016.1145245 . published Nutrition and Cancer
Chemical characterization and cytotoxic potential of an ellagitannin-enriched fraction from Fragaria vesca leaves
Liberal, Joana; Costa, Gustavo; Carmo, Anália; Vitorino, Rui; Marques, Carla; Domingues, Maria Rosário; Domingues, Pedro; et al, Arabian Journal of Chemistry. 3652 - 3666. 8. 12. 2015. http://dx.doi.org/10.1016/j.arabjc.2015.11.014 . 10.1016/j.arabjc.2015.11.014 . published Arabian Journal of Chemistry
Selective cytotoxicity and cell death induced by human amniotic membrane in hepatocellular carcinoma
Mamede, A. C.; Guerra, S.; Laranjo, M.; Carvalho, M. J.; Oliveira, R. C.; Gonçalves, A. C.; Alves, R.; et al, Medical Oncology. 12. 32. 2015. http://dx.doi.org/10.1007/s12032-015-0702-z . 10.1007/s12032-015-0702-z . published Medical Oncology
Effects of X-radiation on lung cancer cells: the interplay between oxidative stress and P53 levels
Mendes, Fernando; Sales, Tiago; Domingues, Cátia; Schugk, Susann; Abrantes, Ana Margarida; Gonçalves, Ana Cristina; Teixo, Ricardo; et al, Medical Oncology. 12. 32. 2015. http://dx.doi.org/10.1007/s12032-015-0712-x . 10.1007/s12032-015-0712-x . published Medical Oncology
Fluorine-18 Fluorodeoxyglucose Uptake in Hepatocellular Carcinoma: Correlation with Glucose Transporters and p53 Expression
Brito, Ana F.; Abrantes, Ana M.; Ribeiro, Marina; Oliveira, Rui; Casalta-Lopes, João; Gonçalves, Ana C.; Sarmento-Ribeiro, Ana B.; Tralhão, José G.; Botelho, Maria F., Journal of Clinical and Experimental Hepatology. 183 - 189. 3. 5. 2015. http://dx.doi.org/10.1016/j.jceh.2015.05.003 . 10.1016/j.jceh.2015.05.003 . published Journal of Clinical and Experimental Hepatology
Influence of P53 on the radiotherapy response of hepatocellular carcinoma
Gomes, Ana R.; Abrantes, Ana M.; Brito, Ana F.; Laranjo, Mafalda; Casalta-Lopes, João E.; Gonçalves, Ana C.; Sarmento-Ribeiro, Ana B.; Botelho, Maria F.; Tralhão, José G., Clinical and Molecular Hepatology. 3. 21. 2015. http://dx.doi.org/10.3350/cmh.2015.21.3.257 . 10.3350/cmh.2015.21.3.257 . published Clinical and Molecular Hepatology
L744,832 and Everolimus Induce Cytotoxic and Cytostatic Effects in Non-Hodgkin Lymphoma Cells
Mendes, José; Gonçalves, Ana Cristina; Alves, Raquel; Jorge, Joana; Pires, Ana; Ribeiro, Ana; Sarmento-Ribeiro, Ana Bela, Pathology & Oncology Research. 301 - 309. 2. 22. 2015. http://dx.doi.org/10.1007/s12253-015-9998-4 . 10.1007/s12253-015-9998-4 . published Pathology & Oncology Research
The importance of radiotherapy on diffuse large B cell lymphoma treatment: a current review
Mendes, Fernando; Domingues, Cátia; Teixo, Ricardo; Abrantes, Ana Margarida; Gonçalves, Ana Cristina; Nobre-Gois, Inês; Jacobetty, Miguel; et al, Cancer and Metastasis Reviews. 511 - 525. 3. 34. 2015. http://dx.doi.org/10.1007/s10555-015-9581-1 . 10.1007/s10555-015-9581-1 . published Cancer and Metastasis Reviews
Oxidative stress and mitochondrial dysfunction play a role in myelodysplastic syndrome development, diagnosis, and prognosis: A pilot study
Gonçalves, A. C.; Cortesão, E.; Oliveiros, B.; Alves, V.; Espadana, A. I.; Rito, L.; Magalhães, E.; et al, Free Radical Research. 1081 - 1094. 9. 49. 2015. http://dx.doi.org/10.3109/10715762.2015.1035268 . 10.3109/10715762.2015.1035268 . published Free Radical Research
Oxidative stress levels are correlated with P15 and P16 gene promoter methylation in myelodysplastic syndrome patients
Gonçalves, Ana Cristina; Cortesão, Emília; Oliveiros, Barbara; Alves, Vera; Espadana, Ana Isabel; Rito, Luís; Magalhães, Emília; et al, Clinical and Experimental Medicine. 333 - 343. 3. 16. 2015. http://dx.doi.org/10.1007/s10238-015-0357-2 . 10.1007/s10238-015-0357-2 . published Clinical and Experimental Medicine
Eritropoietina Sérica como Marcador Prognóstico em Síndrome Mielodisplásica
Cortesão, Emília; Tenreiro, Rita; Ramos, Sofia; Pereira, Marta; César, Paula; Carda, José P.; Gomes, Marília; et al, Acta Médica Portuguesa. 720 - 725. 6. 28. 2015. http://dx.doi.org/10.20344/amp.6518 . 10.20344/amp.6518 . published Acta Médica Portuguesa
Drug transporters play a key role in the complex process of Imatinib resistance in vitro
Alves, Raquel; Fonseca, Ana Raquel; Gonçalves, Ana C.; Ferreira-Teixeira, Margarida; Lima, Joana; Abrantes, Ana M.; Alves, Vera; et al, Leukemia Research. 355 - 360. 3. 39. 2015. http://dx.doi.org/10.1016/j.leukres.2014.12.008 . 10.1016/j.leukres.2014.12.008 . published Leukemia Research
Novel 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine fused chlorins as very active photodynamic agents for melanoma cells
Pereira, Nelson A.M.; Laranjo, Mafalda; Pineiro, Marta; Serra, Arménio C.; Santos, Kathleen; Teixo, Ricardo; Abrantes, Ana Margarida; et al, European Journal of Medicinal Chemistry. 374 - 380. 103. 2015. http://dx.doi.org/10.1016/j.ejmech.2015.08.059 . 10.1016/j.ejmech.2015.08.059 . published European Journal of Medicinal Chemistry
Lung cancer: the immune system and radiation
Mendes, F.; Antunes, C.; Abrantes, A. M.; Gonçalves, A. C.; Nobre-Gois, I.; Sarmento, A. B.; Botelho, M. F.; Rosa, M. S., British Journal of Biomedical Science. 78 - 84. 2. 72. 2015. http://dx.doi.org/10.1080/09674845.2015.11666801 . 10.1080/09674845.2015.11666801 . published British Journal of Biomedical Science
Tamoxifen in combination with temozolomide induce a synergistic inhibition of PKC-pan in GBM cell lines
Balça-Silva, Joana; Matias, Diana; do Carmo, Anália; Girão, Henrique; Moura-Neto, Vivaldo; Sarmento-Ribeiro, Ana Bela; Lopes, Maria Celeste, Biochimica et Biophysica Acta (BBA) - General Subjects. 722 - 732. 4. 1850. 2015. http://dx.doi.org/10.1016/j.bbagen.2014.12.022 . 10.1016/j.bbagen.2014.12.022 . Biochimica et Biophysica Acta (BBA) - General Subjects
Targeting triple-negative breast cancer cells with 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles
Santos, Kathleen; Laranjo, Mafalda; Abrantes, Ana Margarida; Brito, Ana F.; Gonçalves, Cristina; Sarmento Ribeiro, Ana Bela; Botelho, M. Filomena; et al, European Journal of Medicinal Chemistry. 273 - 281. 79. 2014. http://dx.doi.org/10.1016/j.ejmech.2014.04.008 . 10.1016/j.ejmech.2014.04.008 . published European Journal of Medicinal Chemistry
Gamapatias Monoclonais de Significado Indeterminado: Critérios de Diagnóstico e Acompanhamento Clínico
Parreira, Joana; Lúcio, Paulo; João, Cristina; Macedo, Ana; Sarmento, Ana Bela; Geraldes, Catarina; Gonçalves, Cristina; Esteves, Graça, Acta Médica Portuguesa. 661 - 664. 5. 27. 2014. http://dx.doi.org/10.20344/amp.5411 . 10.20344/amp.5411 . published Acta Médica Portuguesa
Beyond the Limits of Oxygen: Effects of Hypoxia in a Hormone-Independent Prostate Cancer Cell Line
Mamede, A. C.; Abrantes, A. M.; Pedrosa, L.; Casalta-Lopes, J. E.; Pires, A. S.; Teixo, R. J.; Gonçalves, A. C.; et al, ISRN Oncology. 1 - 8. 2013. 2013. http://dx.doi.org/10.1155/2013/918207 . 10.1155/2013/918207 . published ISRN Oncology
Study of hepatocellular function in the murine model following hepatic artery selective clamping
Tralhão, José Guilherme; Abrantes, Ana Margarida; Gonçalves, Ana Cristina; Hoti, Emir; Laranjo, Mafalda; Martins, Ricardo; Oliveiros, Bárbara; et al, Acta Cirurgica Brasileira. 657 - 663. 9. 28. 2013. http://dx.doi.org/10.1590/s0102-86502013000900006 . 10.1590/s0102-86502013000900006 . published Acta Cirurgica Brasileira
Selenium Compounds Induced ROS-Dependent Apoptosis in Myelodysplasia Cells
Gonçalves, Ana Cristina; Barbosa-Ribeiro, André; Alves, Vera; Silva, Teresa; Sarmento-Ribeiro, Ana Bela, Biological Trace Element Research. 440 - 447. 3. 154. 2013. http://dx.doi.org/10.1007/s12011-013-9749-x . 10.1007/s12011-013-9749-x . published Biological Trace Element Research
Oxidative stress mediates apoptotic effects of ascorbate and dehydroascorbate in human Myelodysplasia cells in vitro
Gonçalves, Ana Cristina; Alves, Vera; Silva, Teresa; Carvalho, Cristina; Oliveira, Catarina Resende de; Sarmento-Ribeiro, Ana Bela, Toxicology in Vitro. 1542 - 1549. 5. 27. 2013. http://dx.doi.org/10.1016/j.tiv.2013.03.009 . 10.1016/j.tiv.2013.03.009 . published Toxicology in Vitro
Polycyclic Aromatic Hydrocarbons May Contribute for Prostate Cancer Progression
Freitas, Mariana; Alves, Vera; Sarmento-Ribeiro, Ana; Mota-Pinto, Anabela, Journal of Cancer Therapy. 37 - 46. 04. 04. 2013. http://dx.doi.org/10.4236/jct.2013.44a005 . 10.4236/jct.2013.44a005 . published Journal of Cancer Therapy
2-Bromo-5-hydroxyphenylporphyrins for photodynamic therapy: Photosensitization efficiency, subcellular localization and in vivo studies
Laranjo, Mafalda; Serra, Arménio C.; Abrantes, Margarida; Piñeiro, Marta; Gonçalves, Ana C.; Casalta-Lopes, João; Carvalho, Lina; et al, Photodiagnosis and Photodynamic Therapy. 51 - 61. 1. 10. 2013. http://dx.doi.org/10.1016/j.pdpdt.2012.05.003 . 10.1016/j.pdpdt.2012.05.003 . published Photodiagnosis and Photodynamic Therapy
Acção anti-cancerígena da quercetina no Carcinoma Hepatocelular: O papel do GLUT-1
Brito, AF; Ribeiro, M; Abrantes, AM; Gonçalves, AC; Sarmento-Ribeiro, AB; Tralhão, JG; Botelho, MF, Revista Portuguesa de Cirurgia. 23 - 30. 25. 2013. published Revista Portuguesa de Cirurgia
Microenvironment influence on human colon adenocarcinoma phenotypes and matrix metalloproteinase-2, p53 and ß-catenin tumor expressions from identical monoclonal cell tumor in the orthotopic model in athymic nude rats
Priolli, Denise Gonçalves; Abrantes, Ana Margarida; Neves, Silvia; Gonçalves, Ana Cristina; Lopes, Camila Oliveira; Martinez, Natalia Peres; Cardinalli, Izilda Aparecida; Sarmento Ribeiro, Ana Bela; Botelho, Maria Filomena, Scandinavian Journal of Gastroenterology. 309 - 316. 3. 49. 2013. http://dx.doi.org/10.3109/00365521.2013.869350 . 10.3109/00365521.2013.869350 . published Scandinavian Journal of Gastroenterology
Farnesyltransferase Inhibitors: Molecular Evidence of Therapeutic Efficacy in Acute Lymphoblastic Leukemia Through Cyclin D1 Inhibition
Costa, Carlos; Casalta-Lopes, João; Andrade, Carlos; Moreira, Diana; Oliveira, Ana; Gonçalves, Ana Cristina; Alves, Vera; et al, Anticancer Research. 831 - 838. 3. 32. 2012. published Anticancer Research
Effect of miR-34b Overexpression on the Radiosensitivity of Non-small Cell Lung Cancer Cell Lines
Balça-Silva, Joana; Neves, Sílvia; Gonçalves, Ana Cristina; Abrantes, Ana Margarida; Casalta-Lopes, João; Botelho, Maria Filomena; Sarmento-Ribeiro, AB; Silva, Henriqueta, Anticancer Research. 1603 - 1609. 5. 32. 2012. published Anticancer Research
Synthesis of new 2-galactosylthiazolidine-4-carboxylic acid amides. Antitumor evaluation against melanoma and breast cancer cells
Serra, Arménio C.; Rocha Gonsalves, António M. d'A.; Laranjo, Mafalda; Abrantes, Ana M.; Gonçalves, Ana C.; Sarmento-Ribeiro, Ana B.; Botelho, M. Filomena, European Journal of Medicinal Chemistry. 398 - 402. 53. 2012. http://dx.doi.org/10.1016/j.ejmech.2012.04.003 . 10.1016/j.ejmech.2012.04.003 . published European Journal of Medicinal Chemistry
Apoptosis Deregulation Influences Chemoresistance to Azaguanine in Human Leukemic Cell Lines
Sarmento-Ribeiro, A. B.; Dourado, M.; Paiva, A.; Freitas, A.; Silva, T.; Regateiro, F.; Oliveira, C. R., Cancer Investigation. 331 - 342. 5. 30. 2012. http://dx.doi.org/10.3109/07357907.2012.659925 . 10.3109/07357907.2012.659925 . published Cancer Investigation
A possible role for oxidation stress in lymphoid leukaemias and therapeutic failure
Sarmento-Ribeiro, Ana Bela; Proença, Maria T.; Sousa, Isabel; Pereira, Amélia; Guedes, Fátima; Teixeira, Adriana; Oliveira, Catarina R., Leukemia Research. 1041 - 1048. 8. 36. 2012. http://dx.doi.org/10.1016/j.leukres.2012.03.015 . 10.1016/j.leukres.2012.03.015 . published Leukemia Research
Oxidative stress adaptation in aggressive prostate cancer may be counteracted by the reduction of glutathione reductase
Freitas, Mariana; Baldeiras, Inês; Proença, Teresa; Alves, Vera; Mota-Pinto, Anabela; Sarmento-Ribeiro, Ana, FEBS Open Bio. 119 - 128. 1. 2. 2012. http://dx.doi.org/10.1016/j.fob.2012.05.001 . 10.1016/j.fob.2012.05.001 . published FEBS Open Bio
Hepatocellular Carcinoma and Chemotherapy: The Role of p53
Brito, A.F.; Abrantes, A.M.; Pinto-Costa, C.; Gomes, A.R.; Mamede, A.C.; Casalta-Lopes, J.; Gonçalves, A.C.; et al, Chemotherapy. 381 - 386. 5. 58. 2012. http://dx.doi.org/10.1159/000343656 . 10.1159/000343656 . published Chemotherapy
Tumour Hypoxia and Technetium Tracers: In Vivo Studies
M. Abrantes, A.; Serra, E.; Goncalves, C.; Oliveiros, B.; Laranjo, M.; B. Sarmento-Ribeiro, A.; Rocha-Gonsalves, A.; F. Botelho, M., Current Radiopharmaceuticalse. 99 - 105. 2. 5. 2012. http://dx.doi.org/10.2174/1874471011205020099 . 10.2174/1874471011205020099 . published Current Radiopharmaceuticalse
Cytotoxicity of Ascorbic Acid in a Human Colorectal Adenocarcinoma Cell Line (WiDr): In Vitro and In Vivo Studies
Mamede, Ana Catarina; Pires, Ana Salomé; Abrantes, Ana Margarida; Tavares, Sónia Dorilde; Gonçalves, Ana Cristina; Casalta-Lopes, João Eduardo; Sarmento-Ribeiro, Ana Bela; Maia, Jorge Manuel; Botelho, Maria Filomena, Nutrition and Cancer. 1049 - 1057. 7. 64. 2012. http://dx.doi.org/10.1080/01635581.2012.713539 . 10.1080/01635581.2012.713539 . published Nutrition and Cancer
Combined effect of sodium selenite and docetaxel on PC3 metastatic prostate cancer cell line
Freitas, Mariana; Alves, Vera; Sarmento-Ribeiro, Ana Bela; Mota-Pinto, Anabela, Biochemical and Biophysical Research Communications. 713 - 719. 4. 408. 2011. http://dx.doi.org/10.1016/j.bbrc.2011.04.109 . 10.1016/j.bbrc.2011.04.109 . published Biochemical and Biophysical Research Communications
Efflux Pumps Modulation in Colorectal Adenocarcinoma Cell Lines: The Role of Nuclear Medicine
Casalta-Lopes, João; Abrantes, Ana Margarida; Laranjo, Mafalda; Rio, Joana; Gonçalves, Ana Cristina; Oliveiros, Bárbara; Sarmento-Ribeiro, Ana Bela; Botelho, Maria Filomena, Journal of Cancer Therapy. 408 - 417. 03. 02. 2011. http://dx.doi.org/10.4236/jct.2011.23056 . 10.4236/jct.2011.23056 . published Journal of Cancer Therapy
Hypoxia-induced redox alterations and their correlation with 99mTc-MIBI and 99mTc-HL-91 uptake in colon cancer cells
Abrantes, Ana Margarida; Serra, Maria Elisa Silva; Gonçalves, Ana Cristina; Rio, Joana; Oliveiros, Bárbara; Laranjo, Mafalda; Rocha-Gonsalves, António Manuel; Sarmento-Ribeiro, Ana Bela; Botelho, Maria Filomena, Nuclear Medicine and Biology. 125 - 132. 2. 37. 2010. http://dx.doi.org/10.1016/j.nucmedbio.2009.11.001 . 10.1016/j.nucmedbio.2009.11.001 . published Nuclear Medicine and Biology
Development of an Analytical Methodology for Simultaneous Determination of Vincristine and Doxorubicin in Pharmaceutical Preparations for Oncology by HPLC--UV
Rodrigues, A. S.; Lopes, A. R.; Leao, A.; Couceiro, A.; Ribeiro, A. B. S.; Ramos, F.; da Silveira, M. I. N.; de Oliveira, C. R., Journal of Chromatographic Science. 387 - 391. 5. 47. 2009. http://dx.doi.org/10.1093/chromsci/47.5.387 . 10.1093/chromsci/47.5.387 . published Journal of Chromatographic Science
Modelos experimentais em oncologia: O contributo da cultura de células para o conhecimento da biologia do cancro
Cruz, Mariana; Enes, Margarida; Pereira, Marta; Dourado, Marília; Sarmento Ribeiro, Ana Bela; Ribeiro, Ana Bela Sarmento, Revista Portuguesa de Pneumologia (English Edition). 669 - 682. 4. 15. 2009. http://dx.doi.org/10.1016/s2173-5115(09)70140-x . 10.1016/s2173-5115(09)70140-x . published Revista Portuguesa de Pneumologia (English Edition)
Estudo experimental do impacto da clampagem selectiva da veia porta na função hepatocelular
Tralhão, J Guilherme; Abrantes, Ana Margarida; Gonçalves, Ana Cristina; Carvalho, César; Portela, Ivan; Laranjo, Mafalda; Oliveiros, Bárbara; et al, Revista Portuguesa de Cirurgia Cardio-Torácica e Vascular. 171 - 176. 3. 16. 2009. published Revista Portuguesa de Cirurgia Cardio-Torácica e Vascular
Simultaneous evaluation of viability and Bcl-2 in small-cell lung cancer
Santos, A.; Sarmento-Ribeiro, A. B.; de Lima, M. C. Pedroso; Simões, S.; Moreira, J. N., Cytometry Part A. 1165 - 1172. 12. 73A. 2008. http://dx.doi.org/10.1002/cyto.a.20634 . 10.1002/cyto.a.20634 . published Cytometry Part A
Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington’s disease patients
Almeida, Sandra; Sarmento-Ribeiro, Ana Bela; Januário, Cristina; Rego, A Cristina; Oliveira, Catarina R, Biochemical and Biophysical Research Communications. 599 - 603. 4. 374. 2008. http://dx.doi.org/10.1016/j.bbrc.2008.07.009 . 10.1016/j.bbrc.2008.07.009 . published Biochemical and Biophysical Research Communications
CD26/DPPIV expression and 8-azaguanine response in T-acute lymphoblastic leukaemia cell lines in culture
Dourado, Marília; Sarmento, Ana Bela; Pereira, Sofia Vale; Alves, Vera; Silva, Teresa; Pinto, Anabela Mota; Rosa, Manuel Santos, Pathophysiology. 3 - 10. 1. 14. 2007. http://dx.doi.org/10.1016/j.pathophys.2006.09.003 . 10.1016/j.pathophys.2006.09.003 . published Pathophysiology
Cigarette Smoking Increases Oxidative Stress in Prostate Cancer Patients – A Preliminary Study
Freitas, Mariana; Baldeiras, Inês; Proença, Teresa; Pascoal, Rui; Rabaça, Carlos; Valido, Frederico; Mota-Pinto, Anabela; Sarmento-Ribeiro, AB, European Meeting of the Society for Free Radical Research, In Free Radical Research. 51 - 54. 2007. published European Meeting of the Society for Free Radical Research, In Free Radical Research
Transfection of oral cancer cells mediated by transferrin-associated lipoplexes: Mechanisms of cell death induced by herpes simplex virus thymidine kinase/ganciclovir therapy
Neves, Sílvia S.; Sarmento-Ribeiro, Ana B.; Simões, Sérgio P.; Pedroso de Lima, Maria C., Biochimica et Biophysica Acta (BBA) - Biomembranes. 1703 - 1712. 11. 1758. 2006. http://dx.doi.org/10.1016/j.bbamem.2006.08.021 . 10.1016/j.bbamem.2006.08.021 . published Biochimica et Biophysica Acta (BBA) - Biomembranes
Doseamento das granzimas A e B na sarcoidose pulmonar (estudo experimental)
Dourado, Marília; Bento, Joana; Mesquita, Luís; Marques, Alcide; Vale-Pereira, Sofia; Ribeiro, Ana Bela Sarmento; Pinto, Anabela Mota, Revista Portuguesa de Pneumologia. 111 - 133. 2. 11. 2005. http://dx.doi.org/10.1016/s0873-2159(15)30495-5 . 10.1016/s0873-2159(15)30495-5 . published Revista Portuguesa de Pneumologia
Partition of Dopamine Antagonists into Synthetic Lipid Bilayers: the Effect of Membrane Structure and Composition
SARMENTO, ANA BELA; LIMA, M. C. PEDROSO; OLIVEJRA, C. R., Journal of Pharmacy and Pharmacology. 601 - 605. 7. 45. 1993. http://dx.doi.org/10.1111/j.2042-7158.1993.tb05660.x . 10.1111/j.2042-7158.1993.tb05660.x . published Journal of Pharmacy and Pharmacology
5 120 out of 120 Publications
All projects
Information of exclusive responsibility of the researcher 24-11-2024 , from platform CIÊNCIAVITAE.
2024
Relevance of NF-kB and NRF2/KEAP1 pathways as biomarkers of drug response in patients with Multiple Myeloma
LPCC/GSK
Researcher
Funders: Liga Portuguesa Contra o Cancro; GlaxoSmithKline Produtos Farmacêuticos Lda
2023
Relevância clínica das plaquetas como biomarcadores não invasivos no Mieloma Múltiplo - Um estudo piloto
APCL 2023
Principal investigator
Associação Portuguesa Contra a Leucemia; Sociedade Portuguesa de Hematologia; Amgen Biofarmaceutica Lda
Funders: Associação Portuguesa Contra a Leucemia; Sociedade Portuguesa de Hematologia; Amgen Biofarmaceutica Lda
2023
Clinical Relevance of non-invasive biomarkers in bone and soft tissue tumors
NRC-LPCC/CIMAGO 2023
Researcher
Funders: Liga Portuguesa Contra o Cancro Núcleo Regional do Centro
2023
Circular RNAs in hematological neoplasms: Potentialbiomarker from diagnosis to therapy
NRC-LPCC/CIMAGO 2023
Researcher
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro
2022
HemaCirc: CircRNAs as an innovative tool in hematological neoplasms
CIMAGO 08/22
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2022 -
The role of platelets in diagnosis, prognosis and therapeutic monitoring in diffuse large B-cell lymphoma
CIMAGO 06/22
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2022 -
The role of platelets in diagnosis, prognosis and therapeutic monitoring in diffuse large B-cell lymphoma
CIMAGO 06/22
Principal investigator
2022 -
Evaluation of molecular mechanisms of resistance to proteasome inhibitors and immunomodulatory drugs in multiple myeloma
CIMAGO 05/22
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2022 -
Synthetic lethality in acute myeloid leukemia – Role of DNA damage response
CIMAGO 04/22
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2021/02 -
Clinical relevance of platelets as non-invasive biomarkers in diffuse large B-cell lymphoma - A pilot study
NRC-LPCC/CIMAGO 2020,
Supervisor
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro
2021/02 -
Clinical implications of DNA damage repair in acute myeloid leukemia.
SPH02/22
Researcher
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro
2021/01/01 - 2025/12/31
Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
LA/P/0058/2020
Universidade de Coimbra; Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2019/01/01 - 2019/12/31
CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra; Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação; Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2019 -
Molecular characterization and Clinical Relevance of the crosstalk between the NRF2/KEAP1 axis and Erythropoietin in Hematopoietic Stem Cell - Clinical Relevance in Myelodysplastic Syndromes
02/19
Principal investigator
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro; Sociedade Portuguesa de Hematologia
2019 - 2021
Red Transfronteriza de Innovation en Diagnóstico Precoz de Leucemia para envejecimiento saludable IDIAL-NET
POCTEP 2308
Researcher
2018 -
Characterization and Clinical Relevance of the NRF2/KEAP1 axis in the Hematopoietic Stem Cell of Myelodysplastic Syndromes
08/18
Researcher
Sociedade Portuguesa de Hematologia
2018 - 2022
Development of an innovative nanosystem to mediate a combined and multi-target therapeutic strategy to hepatocellular carcinoma
PTDC/BTM-MAT/30916/2017
Researcher
Fundação para a Ciência e a Tecnologia
2018 -
The NRF2-KEAP1 axis as a potential prognostic biomarker and therapeutic target in chronic lymphocytic leukemia.
03/18
Supervisor
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia; Sociedade Portuguesa de Hematologia
2018 - 2020
New diagnostic and therapeutic tools against multidrug resistant tumors - COST action
CA17104
Researcher
2018 -
Identification of new response markers to Bortezomib and Lenalidomide treatment in patients with multiple myeloma - The role of NF-kB and NRF2/KEAP1
04/18
Supervisor
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro; Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2016 - 2018
Epigenetic in Chronic Lymphocytic Leukemia B – Impact in prognosis and therapy.
FMUC-BST-2016-220
Researcher
Universidade de Coimbra Faculdade de Medicina
2015 - 2016
Modulação redox em neoplasias hematológicas – O NRF2 com novo marcador e alvo terapêutico
LPCC-CIMAGO 2015
Supervisor
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro
2015 - 2016
Role of Wingless and Hedgehog signaling pathways in pediatric B acute lymphoblastic leukemia as new prognostic markers and therapeutic targets
LPCC-2015
Supervisor
Liga Portuguesa Contra o Cancro; Pfizer Portugal
2015 - 2017
The role of Hedgehog signaling pathway in pediatric B acute lymphoblastic leukemia as a new prognostic marker and therapeutic target
GAI/2015
Principal investigator
Universidade de Coimbra Faculdade de Medicina
2015 - 2016
Local anesthetics as a new therapeutic approach in oral squamous cell carcinoma - An in vitro study
GAI-2015
Researcher
Universidade de Coimbra Faculdade de Medicina
2014 - 2019
The role of microRNAs for chronic myeloid leukemia therapeutic selection
FMUC-BST-2016-214
Principal investigator
Universidade de Coimbra Faculdade de Medicina; Banco Santander Totta; Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2013 - 2015
Aging, Stress And Chronic Diseases: From Mechanisms to Therapeutics
CENTRO-07-ST24-FEDER-002006
Researcher
2012/04/01 - 2015/09/30
Pathways of adipose tissue dysfunction: a route for obesity- related cancer
PTDC/SAU-MET/121133/2010
Universidade de Coimbra; Universidade de Coimbra Faculdade de Medicina; Unidade Local de Saúde de Coimbra EPE; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2012 - 2013
The cross-talk between oxidative stress and epigenetics – A possible route in myeloid leukaemia
GAI-2012
Principal investigator
Universidade de Coimbra Faculdade de Medicina
2012 - 2018
Characterization of Cellular and Molecular mechanisms involved in Sensitivity and Resistance to BCR-ABL targeted therapies in Chronic Myelogenous Leukemia
18/12
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2012 - 2014
MicroRNAs profile expression in hepatocellular carcinoma – Potencial prognostic and therapeutic value
11/12
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2012 - 2016
Modulação redox em neoplasias hematológicas – O NRF2 com novo marcador e alvo terapêutico
10/12
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2011 - 2012
Strategic Project -LA 1
PEst-C/SAU/LA0001/2011
Researcher
2011/04/04 - 2014/10/02
Synthesis and Pre-clinical Evaluation of Novel Estradiol-Based Indium Complexes for Targeted Radiotherapy of Tumors
PTDC/QUI-QUI/111891/2009
Universidade de Lisboa Instituto Superior Técnico; Universidade de Coimbra; Universidade de Coimbra Faculdade de Medicina; Fundação para a Ciência e a Tecnologia
Funders: Fundação para a Ciência e a Tecnologia
2009 - 2016
Caracterização clínica e molecular da síndrome mielodisplásica – papel da apoptose e dos microRNAs no prognóstico e terapêutica
24/09
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2009 - 2015
Cancro da cavidade oral – Estudo experimental do microambiente tumoral e novos alvos terapêuticos
26/09
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2009 - 2016
Avaliação de Novos Marcadores Moleculares no Cancro Colorectal
25/09
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2009 - 2015
Alterações celulares e moleculares no Mieloma Múltiplo – Implicações clínicas e terapêuticas
23/09
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2009 - 2013
Molecular and Epigenetic Mechanisms Involved in Hepatocarcinoma – The Potential Prognostic Value And Therapeutic Targeted Approach
96560
Researcher
Fundação Calouste Gulbenkian
2009 - 2011
Síndrome metabólica e cancro da mama: implicações no prognóstico e terapêutica
21/09
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2009 - 2016
Avaliação da relação entre o stress oxidativo e modulação epigenética em neoplasias hematológicas - Papel da variabilidade genética/epigenética no risco de desenvolver neoplasias hematológicas e/ou resistência ao tratamento
22/09
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2008 - 2010
Apo2L/TRAIL as a new therapeutic approach in cancer
02/08
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2007 - 2009
O papel do metabolismo energético no desenvolvimento do cancro
26/07
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2007 - 2008
Protocolo ES(H)AP - etopósido, metilprednisolona, citarabina e cisplatina - Estabilidade físico-química e biológica in vitro
01/07
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2007 - 2009
Nutrição e alterações epigenéticas na síndrome mielodisplásica – implicações prognósticas e terapêuticas
07/07
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2007 - 2009
Implementation of a new methodology for prostate cancer diagnosis and prognosis
01/07
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2006 - 2007
Epigenetic Modulation – A new therapeutic approach in hematological neoplasias
GAI-2006
Principal investigator
Universidade de Coimbra Faculdade de Medicina
2006 - 2010
Molecular and genetic targets involved in prostate cancer susceptibility – The influence of oxidative stress and cigarette smoke
03/06
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2006 - 2008
Development of a cellular system for the study of Cr(VI)-induced lung carcinogenesis
16/06
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2006 - 2008
Novas abordagens terapêuticas no cancro da boca - O papel dos inibidores da tirosina cinase e do proteasoma
06/07
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2005 - 2007
Mitochondrial dysfunction in prostate cancer
14/05
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2005 - 2006
Cell signalling and cancer – The role of farnesyl transferase inhibitors in leukemia
GAI-2005
Principal investigator
Universidade de Coimbra Faculdade de Medicina
2005 - 2006
Evaluation of Ubiquitin proteasome system in patients with Chronic Lymphocytic Leukaemias – Bortezomib as a potential therapeutic approach
JC-2005
Principal investigator
Janssen-Cilag Farmacêutica Lda
2005 - 2007
Protein Kinase inhibitors – Molecular and cellular mechanisms of drug resistance to Enzastaurin (LY317615) – a study in cell culture
LILLY 2005
Principal investigator
Lilly Portugal Produtos Farmacêuticos Lda
2004 - 2006
Apoptosis and Hemato-oncological Diseases – TRAIL/Apo2L as a Potential Therapeutics Approach
01/04
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2004 - 2005
Ubiquitin/proteasome System in Hematological Neoplasia – The Proteasome Inhibitors of as Potential Therapeutic Approach
03/04
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2004 - 2005
Apopptosis and new anticarcinogenic agents – The therapeutic potential of TRAIL/Apo2L
GAI-2004
Principal investigator
Universidade de Coimbra Faculdade de Medicina
2004 - 2006
Molecular Alterations in Prostate Cancer – Evaluation of Chromosomal Alterations and Resistance to Apoptosis
02/04
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2002 - 2003
Role of nitric oxide in limphomagenesis – Relation with resistance to chemotherapy
01/02
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2002 - 2003
Proteasome inhibitors and its use in chemotherapy resistance – A Study in leukemic cells in culture
GAI-19/02
Principal investigator
Universidade de Coimbra Faculdade de Medicina
2002 - 2003
DPPIV/CD26 and Cytotoxicity Induced by Anticancer Drugs
IPG-FMUC
Researcher
Universidade de Coimbra Faculdade de Medicina
2002 - 2004
Role of mitochondria in cell death observed in Huntington’s Disease
GAI-2002
Researcher
Universidade de Coimbra Faculdade de Medicina
1997 - 1998
Influence of oxidative stress and membrane alterations in leukemia pathogenesis and in resistance to chemotherapy.
136/97
Principal investigator
1996 - 2000
Phenotypic alterations of the tumor cell and its involvement in resistance to anti-neoplasic drugs
PRODEP
Principal investigator
1990 - 1992
Retina oxidative stress. Involvement in aging and diabetes
JNICT 90/92
Researcher
1989 - 1991
Partition of Dopamine Antagonists into Synthetic Lipid Bilayers - The Effect of Membrane Structure and Composition
JNICT nº87583
Researcher
5 66 out of 66 projects
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