Ana Salomé dos Santos Pires Lourenço

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Overview

Salomé Pires is Assistant Professor at the Faculty of Medicine of the University of Coimbra (UC). She finished the PhD in Biomedical Engineering in 2017 at the Faculty of Sciences and Technology of the University of Coimbra. For the past years, she is part of a multidisciplinary team whose domain includes Oncology and Biophysics. Her main research interests embraces the field of Oncology, exploring new cancer treatment strategies by using cellular and animal models of disease and integrating global networks in oncology; and Radiobiology, characterizing the effects of ionizing radiation on several types of cancers and studying new radiation-based therapeutic anti-cancer approaches. She published 48 full-text papers, 1 book and 6 book chapters, more than 100 abstracts in periodic journals, more than 100 abstracts in conference proceedings, and 19 communications by invitation, all publications with scientific refereeing, having an h-index of 16 (ISI Web of Science (WOS)). She has experience in PhD (4 ongoing) and master students supervision (19 completed and 9 ongoing). As an assistant professor, she currently participates in 29 curricular units of 12 different master's or postgraduate courses. She has already partaken in 17 financed projects, including 4 international consortia, 2 of which I integrated the Management Committee in representation of Portugal. She is also member of the Editorial Board Molecular and Cellular Oncology, a specialty section of Frontiers in Oncology and Frontiers in Cell and Developmental Biology and Topic Editor of the research topic "Advances in Molecular Radiobiology: From Dosimetry to Precision Medicine in Cancer Treatment". She has been awarded 15 prizes and distinctions.

Affiliation

Univ Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR) area of Environment Genetics and Oncobiology (CIMAGO), Institute of Biophysics, Faculty of Medicine, Coimbra, Portugal; Univ Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), Coimbra, Portugal; Clinical Academic Center of Coimbra (CACC), Coimbra, Portugal

Publications

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Information about journal articles, updated at 01-12-2024, from platform CIÊNCIAVITAE.

Evaluation of the Marginal Adaptation of Two Hydraulic Calcium Silicate Cements Used in Apical Plugs: An In Vitro Study

Sara Filipe; José Pedro Martinho; Siri Paulo; Catarina Carvalho; Ana Coelho; Inês Amaro; Eunice Carrilho; et al, Applied Sciences. 2024. https://www.mdpi.com/2076-3417/14/2/480 . 10.3390/app14020480 . Applied Sciences

The Role of Apical Periodontitis Disease in the Development of Bisphosphonate-Related Osteonecrosis of the Jaw: An Animal Study

Manuel Marques-Ferreira; Ana Margarida Abrantes; Anabela Paula; Mafalda Laranjo; Ana Salomé Pires; Francisco Caramelo; Juan José Segura-Egea; et al, Dentistry Journal. 2023. https://doi.org/10.3390/dj11070168 . 10.3390/dj11070168 . Dentistry Journal

Guidelines to Analyze Preclinical Studies Using Perinatal Derivatives

Ana Salomé Pires; Sveva Bollini; Maria Filomena Botelho; Ingrid Lang-Olip; Peter Ponsaerts; Carolina Balbi; Anna Lange-Consiglio; et al, Methods and Protocols. 2023. https://doi.org/10.3390/mps6030045 . 10.3390/mps6030045 . Methods and Protocols

Microleakage Study of a Bulk Fill over an Uncured Adhesive System

Mariana Vaz Pinto; Salomé Pires; Carlos Miguel Marto; Inês Amaro; Ana Coelho; José Sousa; Manuel Marques Ferreira; et al, Journal of Composites Science. 2023. https://doi.org/10.3390/jcs7010040 . 10.3390/jcs7010040 . Journal of Composites Science

The Structural Diversity and Biological Activity of Steroid Oximes

Ana R. Gomes; Ana S. Pires; Fernanda M. F. Roleira; Elisiário J. Tavares-da-Silva, Molecules. 2023. https://doi.org/10.3390/molecules28041690 . 10.3390/molecules28041690 . Molecules

Anti-Algics in the Therapeutic Response of Breast and Urological Cancers

Ana Catarina Matos; João Lorigo; Inês Marques; Ana M Abrantes; Matilde Jóia-Gomes; Sa Couto P; Sa Couto PM; Ana Cristina Gonçalves; et al, International Journal of Molecular Sciences. 2023. https://www.mdpi.com/1422-0067/25/1/468 . 10.3390/ijms25010468 . International Journal of Molecular Sciences

Risk of Second Tumors in Retinoblastoma Survivors after Ionizing Radiation: A Review

Diana Figueiredo; Inês A. Marques; Ana Salomé Pires; Claudia F. Cavaleiro; Luís C. Costa; Guilherme Castela; Joaquim N. Murta; Maria Filomena Botelho; Ana Margarida Abrantes, Cancers. 2023. https://doi.org/10.3390/cancers15225336 . 10.3390/cancers15225336 . Cancers

Synthetic and natural guanidine derivatives as antitumor and antimicrobial agents: A review

Gomes, Ana R.; Varela, Carla L.; Pires, Ana S.; Tavares-da-Silva, Elisiario J.; Roleira, Fernanda M. F., Bioorganic Chemistry. 2023. https://publons.com/wos-op/publon/60991723/ . 10.1016/J.BIOORG.2023.106600 . Bioorganic Chemistry

Application of Perinatal Derivatives on Oncological Preclinical Models: A Review of Animal Studies

Ricardo Teixo; Ana Salomé Pires; Eurico Pereira; Beatriz Serambeque; Inês Alexandra Marques; Mafalda Laranjo; Slavko Mojsilovic; et al, International Journal of Molecular Sciences. 2022. https://doi.org/10.3390/ijms23158570 . 10.3390/ijms23158570 . International Journal of Molecular Sciences

Evaluation of Microleakage of a New Bioactive Material for Restoration of Posterior Teeth: An In Vitro Radioactive Model

Pedro Neves; Salomé Pires; Carlos Miguel Marto; Inês Amaro; Ana Coelho; José Sousa; Manuel Marques Ferreira; et al, Applied Sciences. 2022. https://doi.org/10.3390/app122211827 . 10.3390/app122211827 . Applied Sciences

The Potential Effect of Lidocaine, Ropivacaine, Levobupivacaine and Morphine on Breast Cancer Pre-Clinical Models: A Systematic Review

Matos, Ana Catarina; Marques, Inês Alexandra; Pires, Ana Salomé; Valentim, Ana; Abrantes, Ana Margarida; Botelho, Maria Filomena, International Journal of Molecular Sciences. 3. 23. 2022. http://dx.doi.org/10.3390/ijms23031894 . 10.3390/ijms23031894 . International Journal of Molecular Sciences

Magnetic-Based Human Tissue 3D Cell Culture: A Systematic Review

Inês Alexandra Marques; Carolina Fernandes; Nuno Tiago Tavares; Ana Salomé Pires; Ana Margarida Abrantes; Maria Filomena Botelho, International Journal of Molecular Sciences. 2022. https://doi.org/10.3390/ijms232012681 . 10.3390/ijms232012681 . International Journal of Molecular Sciences

An Overview on Radiation Sensitivity in Hereditary Breast and Ovarian Cancer Syndrome

Diana Gonçalves; Ana Salomé Pires; Inês A. Marques; Inês Gomes; Gabriela Sousa; Maria Filomena Botelho; Ana Margarida Abrantes, Cancers. 3254 - 3254. 13. 14. 2022. https://doi.org/10.3390/cancers14133254 . 10.3390/cancers14133254 . Cancers

Methods and criteria for validating the multimodal functions of perinatal derivatives when used in oncological and antimicrobial applications

Silini, Antonietta R.; Ramuta, Taja Zeleznik; Pires, Ana Salome; Banerjee, Asmita; Dubus, Marie; Gindraux, Florelle; Kerdjoudj, Halima; et al, Frontiers in Bioengineering and Biotechnology. 2022. https://publons.com/wos-op/publon/55432509/ . 10.3389/FBIOE.2022.958669 . Frontiers in Bioengineering and Biotechnology

Acrocomia aculeata (Jacq.) Lodd ex Mart. leaves aqeous extract improves redox-homeostasis and diabetes complications

Monteiro, Tamaeh; Rosendo-Silva, Daniela; Oliveira, S.; Antunes, K.A.; AS Pires; Teixo, Ricardo Jorge Marques; Abrantes, Ana Margarida; et al, European Journal of Clinical Investigation. S1. 51. 2021. http://dx.doi.org/10.1111/eci.13564 . 10.1111/eci.13564 . European Journal of Clinical Investigation

Hypoglycaemic and Antioxidant Properties of Acrocomia aculeata (Jacq.) Lodd Ex Mart. Extract Are Associated with Better Vascular Function of Type 2 Diabetic Rats

Monteiro-Alfredo, Tamaeh; Oliveira, Sara; Amaro, Andreia; Rosendo-Silva, Daniela; Antunes, Katia; Pires, Ana Salomé; Teixo, Ricardo; et al, Nutrients. 8. 13. 2021. http://dx.doi.org/10.3390/nu13082856 . 10.3390/nu13082856 . Nutrients

Alterations of the ghrelin/NPY adipose tissue system as a therapeutic target in type 2 diabetes

Rosendo-Silva, Daniela; Eickhoff, H; Gomes, P.; Viana, S.; AS Pires; Abrantes, Ana Margarida; Reis, F.; et al, European Journal of Clinical Investigation. S1. 51. 2021. http://dx.doi.org/10.1111/eci.13564 . 10.1111/eci.13564 . European Journal of Clinical Investigation

Promising benefits of cold atmospheric plasma-based therapies against bladder cancer

Tavares-Da-Silva, E.; Fernandes, L.; Pereira, E.; Pires, A.S.; Caramelo, F.; Teixeira, P.; Oliveira, R.; et al, European Urology Open Science. 32. 2021. http://dx.doi.org/10.1016/s2666-1683(21)01226-x . 10.1016/s2666-1683(21)01226-x . European Urology Open Science

Study Protocol of a Multicenter Randomized Controlled Trial to Tackle Obesity through a Mediterranean Diet vs. a Traditional Low-Fat Diet in Adolescents: The MED4Youth Study

Boqué, Noemi; Tarro, Lucía; Rosi, Alice; Torrell, Helena; Saldaña, Guillermo; Luengo, Elisa; Rachman, Zeev; et al, International Journal of Environmental Research and Public Health. 9. 18. 2021. http://dx.doi.org/10.3390/ijerph18094841 . 10.3390/ijerph18094841 . International Journal of Environmental Research and Public Health

Design, synthesis, and antitumor activity evaluation of steroidal oximes

Gomes, Ana R.; Pires, Ana S.; Abrantes, Ana M.; Gonçalves, Ana C.; Costa, Saul C.; Varela, Carla L.; Silva, Elisiário T.; Botelho, Maria F.; Roleira, Fernanda M.F., Bioorganic & Medicinal Chemistry. 46. 2021. http://dx.doi.org/10.1016/j.bmc.2021.116360 . 10.1016/j.bmc.2021.116360 . Bioorganic & Medicinal Chemistry

Metabolomic Profiling in Lung Cancer: A Systematic Review

Madama, Daniela; Martins, Rosana; Pires, Ana S.; Botelho, Maria F.; Alves, Marco G.; Abrantes, Ana M.; Cordeiro, Carlos R., Metabolites. 9. 11. 2021. http://dx.doi.org/10.3390/metabo11090630 . 10.3390/metabo11090630 . Metabolites

Oxidative stress in bladder cancer: an ally or an enemy?

Fernando Mendes; Eurico Pereira; Diana Martins; Edgar Tavares-Silva; Ana Salomé Pires; Ana Margarida Abrantes; Arnaldo Figueiredo; Maria Filomena Botelho, Molecular Biology Reports. 2021. https://doi.org/10.1007/s11033-021-06266-4 . 10.1007/s11033-021-06266-4 . Molecular Biology Reports

Impairment of the angiogenic process may contribute to lower success rate of root canal treatments in diabetes mellitus

José P. Martinho; Ana Coelho; Bárbara Oliveiros; Salomé Pires; Ana Margarida Abrantes; Siri Paulo; Ana Catarina Carvalho; et al, International Endodontic Journal. 2021. https://doi.org/10.1111/iej.13572 . 10.1111/iej.13572 . International Endodontic Journal

Oxymestane, a cytostatic steroid derivative of exemestane with greater antitumor activity in non-estrogen-dependent cell lines

Ana S. Pires; Carla L. Varela; Inês A. Marques; Ana M. Abrantes; Cristina Gonçalves; Tiago Rodrigues; Paulo Matafome; et al, The Journal of Steroid Biochemistry and Molecular Biology. 105950 - 105950. 2021. https://doi.org/10.1016/j.jsbmb.2021.105950 . 10.1016/j.jsbmb.2021.105950 . The Journal of Steroid Biochemistry and Molecular Biology

Kinetics of radium-223 and its effects on survival, proliferation and DNA damage in lymph-node and bone metastatic prostate cancer cell lines

Inês A. Marques; Ana M. Abrantes; Ana S. Pires; Ana R. Neves; Francisco J. Caramelo; Tiago Rodrigues; Paulo Matafome; et al, International Journal of Radiation Biology. 1 - 31. 2021. https://doi.org/10.1080/09553002.2021.1906462 . 10.1080/09553002.2021.1906462 . International Journal of Radiation Biology

Oxidative stress in bladder cancer: an ally or an enemy?

Mendes, Fernando José Figueiredo Agostinho D'Abreu; Martins, Diana; Tavares-Silva, Edgar; Pires AS; Pereira, Eurico; Abrantes, Ana Margarida; Figueiredo, Arnaldo; Botelho, Maria Filomena, Molecular Biology Reports. 2021. accepted Molecular Biology Reports

Cold Atmospheric Plasma, a Novel Approach against Bladder Cancer, with Higher Sensitivity for the High-Grade Cell Line

Edgar Tavares-da-Silva; Eurico Pereira; Ana S. Pires; Ana R. Neves; Catarina Braz-Guilherme; Inês A. Marques; Ana M. Abrantes; et al, Biology. 41 - 41. 1. 10. 2021. https://doi.org/10.3390/biology10010041 . 10.3390/biology10010041 . Biology

Acrocomia aculeata (Jacq.) Lodd ex Mart. Leaves Aqeous Extract Improves Redox-Homeostasis and Diabetes Complications

Monteiro, T.; Rosendo-Silva, D.; Oliveira, S.; Antunes, K. A.; Pires, A. S.; Teixo, R.; Abrantes, A. M.; et al, European Journal of Clinical Investigation. 2021. https://publons.com/wos-op/publon/48588676/ . European Journal of Clinical Investigation

Tumour functional imaging by PET

Abrantes, Ana Margarida; Pires, Ana Salomé; Monteiro, Lúcia; Teixo, Ricardo Jorge Marques; Neves, Ana Rita; Tavares, Nuno Tiago; Marques, Inês Alexandra; Botelho, Maria Filomena, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 6. 1866. 2020. http://dx.doi.org/10.1016/j.bbadis.2020.165717 . 10.1016/j.bbadis.2020.165717 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Acute myeloid leukemia sensitivity to metabolic inhibitors: glycolysis showed to be a better therapeutic target

Beatriz Lapa; Ana Cristina Gonçalves; Joana Jorge; Raquel Alves; Ana Salomé Pires; Ana Margarida Abrantes; Margarida Coucelo; et al, Medical Oncology. 8. 37. 2020. https://doi.org/10.1007/s12032-020-01394-6 . 10.1007/s12032-020-01394-6 . Medical Oncology

GLP-1 improves adipose tissue glyoxalase activity and capillarization improving insulin sensitivity in type 2 diabetes

Rodrigues, Tiago; Borges, Patrícia; Mar, Laura; Marques, Daniela; Albano, Miguel; Eickhoff, Hans; Carrêlo, Catarina; et al, Pharmacological Research. 161. 2020. http://dx.doi.org/10.1016/j.phrs.2020.105198 . 10.1016/j.phrs.2020.105198 . Pharmacological Research

Synthesis, Characterization and Evaluation of the Antibacterial and Antitumor Activity of HalogenatedSalen Copper (II) Complexes derived from Camphoric Acid

Pires, Ana Salomé; Batista, João; Murtinho, Dina; Nogueira, Célia; Karamysheva, Anna; Luísa Ramos, M.; Milne, Bruce F.; et al, Applied Organometallic Chemistry. 2020. http://dx.doi.org/10.1002/aoc.5569 . 10.1002/aoc.5569 . Applied Organometallic Chemistry

Iodine-131 metabolic radiotherapy leads to cell death and genomic alterations through NIS overexpression on cholangiocarcinoma

Brito, Ana; Abrantes, Ana; Teixo, Ricardo; Pires, Ana; Ribeiro, Ana; Ferreira, Rafael; Fernandes, Alexandra; et al, International Journal of Oncology. 2020. http://dx.doi.org/10.3892/ijo.2020.4957 . 10.3892/ijo.2020.4957 . published International Journal of Oncology

Efficacy of cold atmospheric plasma against bladder cancer, <i>in vitro</i> studies

Pereira, Eurico; Tavares-da-Silva, Edgar; Neves, Ana R.; Pires, Ana S.; Guilherme, Catarina; Marques, Ines; Abrantes, Ana M.; et al, Medicine. 2020. https://publons.com/wos-op/publon/34354212/ . Medicine

Establishment of a 3D cell culture model of metastatic prostate cancer to evaluate the effects of Radium-223

Tavares, Nuno Tiago; Marques, Ines Alexandra; Pires, Ana Salome; Teixeira, Paulo; Silva, Sandra; Tavares-Silva, Edgar; Caramelo, Francisco; et al, Medicine. 2020. https://publons.com/wos-op/publon/34354214/ . Medicine

Synthesis and antitumor evaluation of new steroidal oximes in several cancer cell lines

Gomes, Ana Rita; Pires, Ana Salome; Abrantes, Ana Margarida; Varela, Carla; Tavares-da-Silva, Elisiario; Botelho, Maria Filomena; Roleira, Fernanda Maria Fernandes, Medicine. 2020. https://publons.com/wos-op/publon/34354215/ . Medicine

Surface-PASylation of ferritin to form stealth nanovehicles enhances in vivo therapeutic performance of encapsulated ellipticine

Pires AS, Applied Materials Today. 2019. http://dx.doi.org/10.1016/j.apmt.2019.100501 . 10.1016/j.apmt.2019.100501 . Applied Materials Today

Evaluation of the efficacy of dentin hypersensitivity treatments - A systematic review and follow-up analysis

Pires AS, Journal of Oral Rehabilitation. 2019. http://dx.doi.org/10.1111/joor.12842 . 10.1111/joor.12842 . Journal of Oral Rehabilitation

The radiobiological effects of Radium-223 in metastatic prostate cancer cells

Marques, I.; Abrantes, Ana Margarida; Pires, A.S.; Neves, A.R.; Tavares, N.T.; Caramelo, F.; Tavares-Silva, E.; et al, European Urology Supplements. e3129 - e3130. 8. 18. 2019. http://dx.doi.org/10.1016/s1569-9056(19)33372-x . 10.1016/s1569-9056(19)33372-x . European Urology Supplements

Radium-223 in metastatic prostate cancer: comparison of 2D and 3D cultures

Tavares, N.T.; Pires, A.S.; Marques, I.; Teixeira, P.; Silva, S.; Tavares-Silva, E.; Costa, G.; et al, European Urology Supplements. 8. 18. 2019. http://dx.doi.org/10.1016/s1569-9056(19)33382-2 . 10.1016/s1569-9056(19)33382-2 . European Urology Supplements

Synthesis of steroidal oximes and epoxides and its antitumor effect against prostate cancer

Gomes, A.R.; Pires, A.S.; Abrantes, A.M.; Varela-Lopes, C.; Marques, I.; Tavares Da Silva, E.; Roleira, F.M.; Botelho, Maria Filomena, European Urology Supplements. e3142 - e3143. 8. 18. 2019. http://dx.doi.org/10.1016/s1569-9056(19)33384-6 . 10.1016/s1569-9056(19)33384-6 . European Urology Supplements

Radium-223 therapy in Metastatic Castration-Resistant Prostate Cancer: effects on tumor and normal cell lines

Balteiro, G; Marques, I; Abrantes, M; Neves, A; Meireles, I; Pires, AS; Costa, G; et al, European Journal of Public Health. Supplement. 29. 2019. http://dx.doi.org/10.1093/eurpub/ckz034.090 . 10.1093/eurpub/ckz034.090 . European Journal of Public Health

Ascorbic Acid Chemosensitizes Colorectal Cancer Cells and Synergistically Inhibits Tumor Growth

Pires AS, Frontiers in Physiology. 2018. http://dx.doi.org/10.3389/fphys.2018.00911 . 10.3389/fphys.2018.00911 . Frontiers in Physiology

Doping ß-TCP as a Strategy for Enhancing the Regenerative Potential of Composite ß-TCP-Alkali-Free Bioactive Glass Bone Grafts. Experimental Study in Rats

Ferreira, Manuel; Brito, Ana; Brazete, Daniela; Pereira, Inês; Carrilho, Eunice; Abrantes, Ana; Pires, Ana; et al, Materials. 1. 12. 2018. http://dx.doi.org/10.3390/ma12010004 . 10.3390/ma12010004 . Materials

Butyrate, a dietary fiber derivative that improves irinotecan effect in colon cancer cells

Encarnação, JC; Pires AS; Amaral, R; Gonçalves, TJ; Laranjo, M; Casalta-Lopes, JE; Gonçalves, AC; et al, The Journal of Nutritional Biochemistry. x. 2018. accepted The Journal of Nutritional Biochemistry

A Radiação: Má ou Boa

Caramelo, Francisco; Abrantes, Ana Margarida; Pires, Ana Salomé; Botelho, Maria Filomena, Revista Internacional em Língua Portuguesa. 137 - 147. 34. 2018. http://dx.doi.org/10.31492/2184-2043.rilp2018.34/pp.137-147 . 10.31492/2184-2043.rilp2018.34/pp.137-147 . Revista Internacional em Língua Portuguesa

Revisiting colorectal cancer animal model - An improved metastatic model for distal rectosigmoid colon carcinoma

Rui Caetano-Oliveira; Marcos António Gomes; Ana Margarida Abrantes; Edgar Tavares-Silva; Marco Carvalho Oliveira; Mafalda Laranjo; Débora Basílio Queirós; et al, Pathophysiology. 89 - 99. 2. 25. 2018. https://doi.org/10.1016/j.pathophys.2018.02.002 . 10.1016/j.pathophys.2018.02.002 . Pathophysiology

Targeted alpha therapy using Radium-223: From physics to biological effects

Marques, I. A.; Neves, A. R.; Abrantes, A. M.; Pires, A. S.; Tavares-da-Silva, E.; Figueiredo, A.; Botelho, M. F., Cancer Treatment Reviews. 2018. https://publons.com/wos-op/publon/14499359/ . 10.1016/J.CTRV.2018.05.011 . Cancer Treatment Reviews

Butyrate, a dietary fiber derivative that improves irinotecan effect in colon cancer cells

Encarnacao, Joao Crispim; Pires, Ana Salome; Amaral, Renata Alexandra; Goncalves, Telmo Jose; Laranjo, Mafalda; Casalta-Lopes, Joao Eduardo; Goncalves, Ana Cristina; et al, The Journal of Nutritional Biochemistry. 2018. https://publons.com/wos-op/publon/14499354/ . 10.1016/J.JNUTBIO.2018.02.018 . The Journal of Nutritional Biochemistry

Radium-223 and metastatic prostate cancer: new insights from cellular studies

Marques, I. A.; Abrantes, A. M.; Neves, A. R.; Pires, A. S.; Costa, G.; Caramelo, F.; Rodrigues, T.; et al, European Journal of Nuclear Medicine and Molecular Imaging. 2017. https://publons.com/wos-op/publon/14937710/ . European Journal of Nuclear Medicine and Molecular Imaging

Dibrominated camphoric acid derived salen complexes: Synthesis, characterization and cytotoxic activity

Silva Serra, M.E.; Murtinho, D.; da Rocha, Z.N.; Pires, A.S.; Baptista, J.G.; Abrantes, A.M.; Laranjo, M.; et al, Polyhedron. 147 - 156. 137. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85028955641&partnerID=MN8TOARS . 10.1016/j.poly.2017.08.038 . Polyhedron

Radium-223 and metastatic prostate cancer: new insights from cellular studies

Marques, IA; Abrantes, AM; Neves, AR; Pires, AS; Costa, G; Caramelo, F; Rodrigues, T; et al, European Journal of Nuclear Medicine and Molecular Imaging. 119 - 956. S2. 44. 2017. 10.1007/s00259-017-3822-1 . published European Journal of Nuclear Medicine and Molecular Imaging

Can the regenerative potential of an alkali-free bioactive glass composition be enhanced when mixed with resorbable ß-TCP?

Ferreira, Manuel M.; Brito, Ana F.; Marques, Catarina F.; Freitas, Luis F.; Carrilho, Eunice; Abrantes, Ana M.; Pires, Ana S.; et al, Ceramics International. Inpress - Inpress. Inpress. 2017. 10.1016/j.ceramint.2017.12.099 . published Ceramics International

Radiotherapy Effects on Immune System of Patients with Solid and Hematopoietic Tumors

Mendes, FJ; Domingues, C; Rodrigues-Santos, P; Alves, V; Góis, IN; Abrantes, AM; Gonçalves, AC; et al, Cell Biology: Research & Therapy. n_a - n_a. 01. 05. 2016. 10.4172/2324-9293.1000124 . published Cell Biology: Research & Therapy

Hyperbaric oxygen therapy combined with photodynamic therapy as a new therapeutic approach against retinoblastoma

Neves, A.; Abrantes, A.; Pires, A.; Teixo, R.; Botelho, MF; Neves, AR; Abrantes, AM; Pires, AS; Teixo, RJ, European Journal of Cancer. S144 - S144. S1. 61. 2016. 10.1016/S0959-8049(16)61507-1 . published European Journal of Cancer

The role of immune system exhaustion on cancer cell escape and anti-tumor immune induction after irradiation

Mendes, FJ; Domingues, C; Rodrigues-Santos, P; Abrantes, AM; Gonçalves, AC; Estrela, J; Encarnação, JC; et al, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 168 - 175. 2. 1865. 2016. 10.1016/j.bbcan.2016.02.002 . published Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Ascorbic acid and colon cancer: an oxidative stimulus to cell death depending on cell profile

Pires, AS; Marques, CR; Encarnação, JC; Abrantes, AM; Mamede, AC; Laranjo, M; Gonçalves, AC; Sarmento-Ribeiro, AB; Botelho, MF, European Journal of Cell Biology. 208 - 218. 6-7. 95. 2016. 10.1016/j.ejcb.2016.04.001 . published European Journal of Cell Biology

Combined dual effect of modulation of human neutrophils - oxidative burst and inhibition of colon cancer cells proliferation by hydroxycinnamic acid derivatives

Tavares-da-Silva, EJ; Varela, C; Pires, AS; Encarnação, JC; Abrantes, AM; Botelho, MF; Carvalho, RA; et al, Bioorganic & Medicinal Chemistry. 3556 - 3564. 16. 24. 2016. 10.1016/j.bmc.2016.05.065 . published Bioorganic & Medicinal Chemistry

Radium-223: kinetics and therapeutic response against metastatic prostate cancer

Marques, I. A.; Abrantes, A. M.; Pires, A. S.; Costa, G.; Caramelo, F.; Tavares-Silva, E.; Botelho, M. F., European Journal of Nuclear Medicine and Molecular Imaging. 2016. https://publons.com/wos-op/publon/6366050/ . European Journal of Nuclear Medicine and Molecular Imaging

Quercetin in Cancer Treatment, Alone or in Combination with Conventional Therapeutics?

Brito, Ana Filipa; Ribeiro, Marina; Abrantes, Ana Margarida; Pires, Ana Salome; Teixo, Ricardo Jorge; Tralhao, Jose Guilherme; Botelho, Maria Filomena, Current Medicinal Chemistry. 2015. https://publons.com/wos-op/publon/6365992/ . 10.2174/0929867322666150812145435 . Current Medicinal Chemistry

Revisit dietary fiber on colorectal cancer: butyrate and its role on prevention and treatment

Encarnação, JC; Abrantes, AM; Pires, AS; Botelho, MF, Cancer and Metastasis Reviews. 465 - 478. 3. 34. 2015. 10.1007/s10555-015-9578-9 . published Cancer and Metastasis Reviews

Synthesis, characterization and assessment of the cytotoxic activity of Cu(II), Fe(III) and Mn(III) complexes of camphoric acid-derived salen ligands

Murtinho, D; da Rocha, ZN; Pires, AS; Jiménez, RP; Abrantes, AM; Laranjo, M; Mamede, AC; et al, Applied Organometallic Chemistry. 425 - 432. 7. 29. 2015. 10.1002/aoc.3309 . published Applied Organometallic Chemistry

Quercetin in cancer treatment, alone or in combination with conventional therapeutics?

Brito, AF; Ribeiro, M; Abrantes, AM; Pires, AS; Teixo, RJ; Tralhão, JG; Botelho, MF; et al, Current Medicinal Chemistry. 3025 - 3039. 26. 22. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942155857&partnerID=MN8TOARS . published Current Medicinal Chemistry

May butyrate interfere with Warburg effect in colon cancer cells?

Goncalves, T. J.; Pires, A. S.; Encarnacao, J. C.; Casalta, J. E.; Goncalves, A. C.; Abrantes, A. M.; Sarmento-Ribeiro, A. B.; Botelho, M. F., European Journal of Nuclear Medicine and Molecular Imaging. 2014. https://publons.com/wos-op/publon/6366027/ . European Journal of Nuclear Medicine and Molecular Imaging

Ascorbic acid-induced cytotoxicity in colon cancer cell lines

Pires, A. S.; Marques, C. R.; Encarnacao, J. C.; Goncalves, T. J.; Mamede, A. C.; Casalta-Lopes, J. E.; Goncalves, A. C.; et al, European Journal of Cancer. 2014. https://publons.com/wos-op/publon/6366039/ . 10.1016/S0959-8049(14)50664-8 . European Journal of Cancer

Effect of Amniotic Membrane Proteins in Human Cancer Cell Lines: An Exploratory Study

Mamede, AC; Laranjo, M; Carvalho, MJ; Abrantes, AM; Pires, AS; Brito, AF; Moura, P; Maia, CJ; Botelho, MF, The Journal of Membrane Biology. 357 - 360. 4. 247. 2014. 10.1007/s00232-014-9642-3 . published The Journal of Membrane Biology

Butyrate and irinotecan combination as a new therapeutic approach for colon cancer

Encarnação, JC; Gonçalves, TJ; Casalta-Lopes, JE; Gonçalves, AC; Abrantes, AM; Sarmento-Ribeiro, AB; Botelho, MF; Pires, AS, European Journal of Cancer. S180 - S180. S5. 50. 2014. 10.1016/S0959-8049(14)50659-4 . published European Journal of Cancer

Exploring the metabolic profile of colorectal cancer cells from different origin

Abrantes, A.; Tavares, L.; Pires, AS; Laranjo, M; Casalta-Lopes, J.; Carvalho, RA; Botelho, MF; et al, European Journal of Cancer. S33 - S33. S5. 50. 2014. 10.1016/S0959-8049(14)50124-4 . published European Journal of Cancer

752: Anti-cancer proteins found in amniotic membrane: extraction, identification and cellular effects

Mamede, AC; Guerra, S; Laranjo, M; Brito, AF; Pires, AS; Carvalho, MJ; Moura, P; et al, European Journal of Cancer. S181 - S181. S5. 50. 2014. 10.1016/S0959-8049(14)50660-0 . published European Journal of Cancer

Metabolic Effects of Hypoxia in Colorectal Cancer by 13C NMR Isotopomer Analysis

Abrantes, AM; Tavares, LC; Pires, AS; Casalta-Lopes, JE; Mendes, C; Simões, M; Grazina, MM; Carvalho, RA; Botelho, MF, BioMed Research International. 1 - 10. 2014. 2014. 2014. 10.1155/2014/759791 . published BioMed Research International

Beyond the limits of oxygen: effects of hypoxia in a hormone-independent prostate cancer cell line

Mamede, AC; Abrantes, AM; Pedrosa, L; Casalta-Lopes, JE; Pires, AS; Teixo, RJ; Gonçalves, AC; et al, ISRN Oncology. 1 - 8. 918207. 2013. 2013. 10.1155/2013/918207 . published ISRN Oncology

Effects of amniotic membrane proteins on mitochondrial activity, protein synthesis, cell viability and DNA of prostate cancer cell lines: Preliminary results

Mamede, A. C.; Laranjo, M.; Moreira, S.; Carvalho, M. J.; Abrantes, A. M.; Pires, A. S.; Casalta-Lopes, J. E.; Maia, C. J.; Botelho, M. F., European Journal of Cancer. 2013. https://publons.com/wos-op/publon/1429477/ . European Journal of Cancer

Is there a true correlation between cytotoxic effect and uptake of ascorbic acid in colorectal cancer cells?

Pires, A. S.; Marques, C. R.; Almeida, A. R.; Mamede, A. C.; Abrantes, A. M.; Tralhao, J. G.; Sarmento-Ribeiro, A. B.; Botelho, M. F., European Journal of Nuclear Medicine and Molecular Imaging. 2013. https://publons.com/wos-op/publon/6366003/ . European Journal of Nuclear Medicine and Molecular Imaging

Is there a synergistic effect between ascorbic acid and conventional chemotherapy in the treatment of colorectal carcinoma?

Marques, C. R.; Pires, A. S.; Encarnacao, J. C.; Goncalves, T. J.; Mamede, A. C.; Casalta-Lopes, J.; Goncalves, A. C.; et al, European Journal of Cancer. 2013. https://publons.com/wos-op/publon/6365977/ . European Journal of Cancer

Hypoxia induced alterations on cell metabolism - an in vitro study in three different colorectal carcinoma cell lines

Abrantes, A.; Pires, A. S.; Laranjo, M.; Mamede, A. C.; Brito, A. F.; Casalta-Lopes, J.; Goncalves, A. C.; Sarmento-Ribeiro, A. B.; Botelho, M. F., European Journal of Cancer. 2013. https://publons.com/wos-op/publon/2326903/ . European Journal of Cancer

Sodium butyrate reduces 18F-FDG uptake in two colon cancer cell lines

Goncalves, T. J.; Pires, A. S.; Encamacao, J. C.; Marques, C. R.; Casalta-Lopes, J. E.; Tralhao, J. G.; Abrantes, A. M.; Botelho, M. F., European Journal of Nuclear Medicine and Molecular Imaging. 2013. https://publons.com/wos-op/publon/6366002/ . European Journal of Nuclear Medicine and Molecular Imaging

Ascorbic acid and colon carcinoma: correlation between uptake and cytotoxic effect

Almeida, A. R.; Pires, A. S.; Marques, C. R.; Mamede, A. C.; Casalta-Lopes, J.; Abrantes, A. M.; Sarmento-Ribeiro, A. B.; Botelho, M. F., European Journal of Cancer. 2013. https://publons.com/wos-op/publon/6366008/ . European Journal of Cancer

Influence of sodium butyrate on 18F-FDG uptake in two colon cancer cell lines

Goncalves, T. J.; Pires, A. S.; Encarnacao, J. C.; Marques, C. R.; Casalta-Lopes, J.; Abrantes, A. M.; Botelho, M. F., European Journal of Cancer. 2013. https://publons.com/wos-op/publon/6365982/ . European Journal of Cancer

Cytotoxicity of Ascorbic Acid in a Human Colorectal Adenocarcinoma Cell Line (WiDr): In Vitro and In Vivo Studies

Mamede, AC; Pires, AS; Abrantes, AM; Tavares, SD; Gonçalves, AC; Casalta-Lopes, JE; Sarmento-Ribeiro, AB; Maia, JM; Botelho, MF, Nutrition and Cancer. 1049 - 1057. 7. 64. 2012. 10.1080/01635581.2012.713539 . published Nutrition and Cancer

Prostate Cancer - What Happens Beyond the Limits of Oxygen?

Pedrosa, L.; Abrantes, A. M.; Mamede, A. C.; Pires, A. S.; Botelho, M. F., European Journal of Cancer. 2012. https://publons.com/wos-op/publon/6365891/ . 10.1016/S0959-8049(12)70990-5 . European Journal of Cancer

18F-FDG: WHAT IS ITS ROLE IN PROSTATE CANCER?

Pedrosa, L.; Mamede, A. C.; Abrantes, A. M.; Pires, A. S.; Teixo, R. J.; Goncalves, A. C.; Sarmento-Ribeiro, A. B.; Botelho, M. F., Annals of Oncology. 2012. https://publons.com/wos-op/publon/6365914/ . Annals of Oncology

ASCORBIC ACID AND ITS THERAPEUTIC POTENTIAL AGAINST COLORECTAL ADENOCARCINOMA

Pires, Ana; Mamede, Ana; Silva, Vanessa; Abrantes, Ana; Brito, Ana; Goncalves, Ana; Sarmento-Ribeiro, Ana; Botelho, Maria, Annals of Oncology. 2012. https://publons.com/wos-op/publon/6366014/ . Annals of Oncology

ANTI-PROLIFERATIVE EFFECT OF CISPLATIN, DOXORUBICIN AND EPIRUBICIN IN TWO PROSTATE CANCER CELL LINES

Mamede, A. C.; Abrantes, A. M.; Pedrosa, L.; Pires, A. S.; Maia, C. J.; Botelho, M. F., Annals of Oncology. 2012. https://publons.com/wos-op/publon/1007500/ . Annals of Oncology

Ascorbic Acid Effect in Two Different Cell Lines of Colorectal Adenocarcinoma - in Vitro and in Vivo Studies

Pires, A. S.; Mamede, A. C.; Silva, V. S.; Abrantes, A. M.; Goncalves, A. C.; Sarmento-Ribeiro, A. B.; Botelho, M. F., European Journal of Cancer. 2012. https://publons.com/wos-op/publon/6365889/ . 10.1016/S0959-8049(12)71006-7 . European Journal of Cancer

AN IN VIVO STUDY TO ANALYSE THE POTENTIAL OF 188RE-PEI-MP FOR METABOLIC RADIOTHERAPY OF BLADDER CARCINOMA

Ferreira, S.; Laranjo, M.; Abrantes, A. M.; Brito, A.; Pires, A. S.; Metello, L. F.; Zeevaart, J.; et al, Annals of Oncology. 2012. https://publons.com/wos-op/publon/2326909/ . Annals of Oncology

Radiolabelling of ascorbic acid: A new clue to clarify its action as an anticancer agent?

Mamede, A.C.; Abrantes, A.M.; Pires, A.S.; Tavares, S.D.; Serra, M.E.; Maia, J.M.; Botelho, M.F.; et al, Current Radiopharmaceuticals. 106 - 112. 2. 5. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857135554&partnerID=MN8TOARS . 10.2174/1874471011205020106 . published Current Radiopharmaceuticals

EFFECT OF a-TOCOFERIL SUCCINATE IN TWO DIFFERENT CELL LINES OF COLORECTAL ADENOCARCINOMA

Silva, Vanessa; Pires, Ana; Abrantes, Ana; Brito, Ana; Goncalves, Ana; Sarmento-Ribeiro, Ana; Botelho, Maria, Annals of Oncology. 2012. https://publons.com/wos-op/publon/6366058/ . Annals of Oncology

THE IN VITRO AND IN VIVO EFFECT OF ASCORBIC ACID IN A MELANOMA CELL LINE: A NEW MECHANISM OF ACTION?

Pires, A. S.; Mamede, A. C.; Abrantes, A. M.; Brito, A. F.; Laranjo, M.; Goncalves, A. C.; Sarmento-Ribeiro, A. B.; Botelho, M. F., Annals of Oncology. 2012. https://publons.com/wos-op/publon/2326926/ . Annals of Oncology

THE ROLE OF GOSSYPOL IN THE TREATMENT OF HEPATOCELLULAR CARCINOMA: STUDIES WITH 18F-FDG

Brito, A. F.; Abrantes, A. M.; Mamede, A. C.; Pires-Lourenco, A. S.; Tralhao, J. G.; Botelho, M. F., Annals of Oncology. 2012. https://publons.com/wos-op/publon/6365913/ . Annals of Oncology

CHEMOTHERAPY OR RADIOTHERAPY PLUS ASCORBIC ACID: A SYNERGIC EFFECT AGAINST COLORECTAL ADENOCARCINOMA?

Pires, Ana Salome; Mamede, Ana Catarina; Abrantes, Ana Margarida; Matos, Carolina Caetano; Brito, Ana Filipa; Casalta-Lopes, Joao Eduardo; Laranjo, Mafalda; et al, Annals of Oncology. 2011. https://publons.com/wos-op/publon/2326928/ . Annals of Oncology

Auger Electrons and Metabolic Therapy: Wanted, Needed ... and Coming Soon to a Place Near You!

Metello, L. F.; Cunha, L.; Tavares, A.; Fonseca, A.; Soares, S.; Abrantes, A. M.; Pires, A. S.; Laranjo, M.; Botelho, M. F., European Journal of Nuclear Medicine and Molecular Imaging. 2008. https://publons.com/wos-op/publon/2326970/ . European Journal of Nuclear Medicine and Molecular Imaging

All projects

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Information of exclusive responsibility of the researcher 01-12-2024 , from platform CIÊNCIAVITAE.

2022/10/26 - 2026/10/25

INE-CSC- Implementation Network Europe for Cancer Survivorship Care

CA21152

Researcher

Universidade de Coimbra Faculdade de Medicina

Funders: European Cooperation in Science and Technology

2020/01

Estratificação do Risco na resposta à radiação ionizante na Síndrome Hereditária para cancro da mama e do ovário associada aos genes BRCA1/2

ND

Researcher

Faculdade de Medicina da Universidade de Coimbra; Coimbra Institute for Clinical and Biomedical Research

Funders: Núcleo Regional do Centro da Liga Portuguesa Contra o Cancro (NRC-LPCC) / Centro de Investigação em Meio Ambiente Genética e Oncobiologia (CIMAGO)

2019/05 - 2022

Mediterranean Enriched Diet for tackling Youth Obesity

PRIMA/0004/2018

Researcher

Universidade de Coimbra Faculdade de Medicina

Funders: Fundação para a Ciência e a Tecnologia

2018/10/16 - 2022/10/15

International Network for Translating Research on Perinatal Derivatives into Therapeutic Approaches

CA17116

Researcher

Funders: European Cooperation in Science and Technology

2017/01 - 2017/12

O sistema cancro-imunidade como alvo da terapia com a membrana amniótica humana no carcinoma hepatocelular

CIMAGO 04/2017

Researcher

Faculdade de Medicina da Universidade de Coimbra; Coimbra Institute for Clinical and Biomedical Research

Funders: Núcleo Regional do Centro da Liga Portuguesa Contra o Cancro (NRC-LPCC) / Centro de Investigação em Meio Ambiente Genética e Oncobiologia (CIMAGO)

2017/01 -

Estudo de novos factores de prognóstico genético em tumores vesicais

CIMAGO 03/2017

Researcher

Faculdade de Medicina da Universidade de Coimbra; Coimbra Institute for Clinical and Biomedical Research

Funders: Núcleo Regional do Centro da Liga Portuguesa Contra o Cancro (NRC-LPCC) / Centro de Investigação em Meio Ambiente Genética e Oncobiologia (CIMAGO)

2016 -

Estudo de novos factores de prognóstico genético em tumores vesicais

CIMAGO 02/2016

Researcher

Faculdade de Medicina da Universidade de Coimbra; Centro Hospitalar e Universitário de Coimbra

Funders: Associação Portuguesa de Urologia; Bayer Portugal SA

2016/01 -

O papel da microflora e do microbioma na patologia intestinal: da nutrição à clínica.

CIMAGO 01/2016

Researcher

Faculdade de Medicina da Universidade de Coimbra

2016/07 - 2019/06

Réseau Européen de Recherche translationnelle et d'Innovation en oncologie

SOE1/P1/F0082

Researcher

Universidade de Coimbra Faculdade de Medicina

Funders: European Regional Development Fund

2016 - 2017

O sistema cancro-imunidade como alvo da terapia com a membrana amniótica humana no carcinoma hepatocelular

FIS-FIS-2015-01_ONC

Funders: INFARMED

2015/01 - 2015/12

GLUT-1: um alvo terapêutico para tumores primários do fígado?

CIMAGO 09/12

Researcher

Universidade de Coimbra

2015 -

Células Tumorais Circulantes no Carcinoma da Próstata Localizado - Perfil Metabólico e Imunológico e Correlação com Agressividade Clínica do Tumor

CIMAGO 01/2014

Researcher

Faculdade de Medicina da Universidade de Coimbra; Centro Hospitalar e Universitário de Coimbra

Funders: Associação Portuguesa de Urologia; Jaba Recordati SA

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