Ana Patrícia Figueiredo Rocha Simões

Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions

Canas, Paula M.; Porciúncula, Lisiane O.; Simões, Ana Patrícia; Augusto, Elisabete; Silva, Henrique B.; Machado, Nuno J.; Gonçalves, Nélio; et al, eneuro. ENEURO.0385 - 18.2018. 6. 5. 2018. http://dx.doi.org/10.1523/eneuro.0385-18.2018 . 10.1523/eneuro.0385-18.2018 . published eneuro

Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses

Machado, Nuno J.; Simões, Ana Patrícia; Silva, Henrique B.; Ardais, Ana Paula; Kaster, Manuella P.; Garção, Pedro; Rodrigues, Diana I.; et al, Molecular Neurobiology. 1552 - 1563. 2. 54. 2017. http://dx.doi.org/10.1007/s12035-016-9774-9 . 10.1007/s12035-016-9774-9 . published Molecular Neurobiology

Adenosine A2A Receptors in the Amygdala Control Synaptic Plasticity and Contextual Fear Memory

Simões, Ana Patrícia; Machado, Nuno J; Gonçalves, Nélio; Kaster, Manuella P; Simões, Ana T; Nunes, Ana; Pereira de Almeida, Luís; et al, Neuropsychopharmacology. 2862 - 2871. 12. 41. 2016. http://dx.doi.org/10.1038/npp.2016.98 . 10.1038/npp.2016.98 . published Neuropsychopharmacology

ATP P2Y1 receptors control cognitive deficits and neurotoxicity but not glial modifications induced by brain ischemia in mice

Carmo, Marta R. S.; Simões, Ana Patrícia; Fonteles, Analu A.; Souza, Carolina M.; Cunha, Rodrigo A.; Andrade, Geanne M., European Journal of Neuroscience. 614 - 622. 4. 39. 2014. http://dx.doi.org/10.1111/ejn.12435 . 10.1111/ejn.12435 . published European Journal of Neuroscience

Predominant loss of glutamatergic terminal markers in a ß-amyloid peptide model of Alzheimer's disease

Canas, Paula M.; Simões, Ana Patrícia; Rodrigues, Ricardo J.; Cunha, Rodrigo A., Neuropharmacology. 51 - 56. 76. 2014. http://dx.doi.org/10.1016/j.neuropharm.2013.08.026 . 10.1016/j.neuropharm.2013.08.026 . published Neuropharmacology

Blockade of adenosine A2A receptors prevents interleukin-1ß-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway

Simões, Ana Patrícia; Duarte, João A; Agasse, Fabienne; Canas, Paula Margarida; Tomé, Angelo R; Agostinho, Paula; Cunha, Rodrigo A, Journal of Neuroinflammation. 1. 9. 2012. http://dx.doi.org/10.1186/1742-2094-9-204 . 10.1186/1742-2094-9-204 . published Journal of Neuroinflammation

Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction

Rebola, Nelson; Simões, Ana Patrícia; Canas, Paula M.; Tomé, Angelo R.; Andrade, Geanne M.; Barry, Claire E.; Agostinho, Paula M.; Lynch, Marina A.; Cunha, Rodrigo A., Journal of Neurochemistry. 100 - 111. 1. 117. 2011. http://dx.doi.org/10.1111/j.1471-4159.2011.07178.x . 10.1111/j.1471-4159.2011.07178.x . published Journal of Neurochemistry

Key Modulatory Role of Presynaptic Adenosine A2AReceptors in Cortical Neurotransmission to the Striatal Direct Pathway

Quiroz, César; Luján, Rafael; Uchigashima, Motokazu; Simoes, Ana Patrícia; Lerner, Talia N.; Borycz, Janusz; Kachroo, Anil; et al, The Scientific World JOURNAL. 1321 - 1344. 9. 2009. http://dx.doi.org/10.1100/tsw.2009.143 . 10.1100/tsw.2009.143 . published The Scientific World JOURNAL

GDNF control of the glutamatergic cortico-striatal pathway requires tonic activation of adenosine A2A receptors

Gomes, Catarina A. R. V.; Simões, Patrícia F.; Canas, Paula M.; Quiroz, César; Sebastião, Ana M.; Ferré, Sergi; Cunha, Rodrigo A.; Ribeiro, Joaquim A., Journal of Neurochemistry. 1208 - 1219. 5. 108. 2009. http://dx.doi.org/10.1111/j.1471-4159.2009.05876.x . 10.1111/j.1471-4159.2009.05876.x . published Journal of Neurochemistry

Methamphetamine Changes NMDA and AMPA Glutamate Receptor Subunit Levels in the Rat Striatum and Frontal Cortex

Simões, Patrícia F.; Silva, Ana P.; Pereira, Frederico C.; Marques, Elsa; Milhazes, Nuno; Borges, Fernanda; Ribeiro, Carlos F.; Macedo, Tice R., Annals of the New York Academy of Sciences. 232 - 241. 1. 1139. 2008. http://dx.doi.org/10.1196/annals.1432.028 . 10.1196/annals.1432.028 . published Annals of the New York Academy of Sciences

Methamphetamine induces alterations on hippocampal NMDA and AMPA receptor subunit levels and impairs spatial working memory

Simões, P.F.; Silva, A.P.; Pereira, F.C.; Marques, E.; Grade, S.; Milhazes, N.; Borges, F.; Ribeiro, C.F.; Macedo, T.R., Neuroscience. 433 - 441. 2. 150. 2007. http://dx.doi.org/10.1016/j.neuroscience.2007.09.044 . 10.1016/j.neuroscience.2007.09.044 . published Neuroscience

Activity and expression of a virulence factor, gelatinase, in dairy enterococci

Lopes, Maria de Fátima Silva; Simões, Ana Patrícia; Tenreiro, Rogério; Marques, José Joaquim Figueiredo; Crespo, Maria Teresa Barreto, International Journal of Food Microbiology. 208 - 214. 3. 112. 2006. http://dx.doi.org/10.1016/j.ijfoodmicro.2006.09.004 . 10.1016/j.ijfoodmicro.2006.09.004 . published International Journal of Food Microbiology