Cátia Filipa Lourenço Marques

A High Fat/Cholesterol Diet Recapitulates Some Alzheimer’s Disease-Like Features in Mice: Focus on Hippocampal Mitochondrial Dysfunction

Mancini, Gianni; Dias, Candida; Lourenço, Catia F.; Laranjinha, Joao; de Bem, Andreza; Ledo, Ana, Journal of Alzheimer's Disease. 1619 - 1633. 4. 82. 2021. http://dx.doi.org/10.3233/jad-210122 . 10.3233/jad-210122 . Journal of Alzheimer's Disease

The bioactivity of neuronal-derived nitric oxide in aging and neurodegeneration: Switching signaling to degeneration

Ledo, A; Lourenço, C.F.; Cadenas, E; Barbosa, R.M.; Laranjinha, J., Free Radical Biology and Medicine. 2020. http://dx.doi.org/10.1016/j.freeradbiomed.2020.11.005 . 10.1016/j.freeradbiomed.2020.11.005 . Free Radical Biology and Medicine

Platinized carbon fiber-based glucose microbiosensor designed for metabolic studies in brain slices

Lourenço, Cátia F.; Caetano, Miguel; Ledo, Ana; Barbosa, Rui M., Bioelectrochemistry. 130. 2019. http://dx.doi.org/10.1016/j.bioelechem.2019.06.010 . 10.1016/j.bioelechem.2019.06.010 . Bioelectrochemistry

Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices

Dias, C.; Lourenço, C.F.; Barbosa, R.M.; Laranjinha, J.; Ledo, A., Analytical Biochemistry. 43 - 50. 551. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85047068802&partnerID=MN8TOARS . 10.1016/j.ab.2018.05.010 . Analytical Biochemistry

Age-Dependent Impairment of Neurovascular and Neurometabolic Coupling in the Hippocampus

Lourenço, Cátia F.; Ledo, Ana; Caetano, Miguel; Barbosa, Rui M.; Laranjinha, João, Frontiers in Physiology. 9. 2018. http://dx.doi.org/10.3389/fphys.2018.00913 . 10.3389/fphys.2018.00913 . Frontiers in Physiology

Concurrent measurements of neurochemical and electrophysiological activity with microelectrode arrays: New perspectives for constant potential amperometry

Ana Ledo; Cátia F. Lourenço; João Laranjinha; Greg A. Gerhardt; Rui M. Barbosa, Current Opinion in Electrochemistry. 129 - 140. 12. 2018. https://doi.org/10.1016/j.coelec.2018.05.018 . 10.1016/j.coelec.2018.05.018 . Current Opinion in Electrochemistry

Neurometabolic and electrophysiological changes during cortical spreading depolarization: multimodal approach based on a lactate-glucose dual microbiosensor arrays

Cátia F. Lourenço; Ana Ledo; Greg A. Gerhardt; João Laranjinha; Rui M. Barbosa, Scientific Reports. 1. 7. 2017. https://doi.org/10.1038/s41598-017-07119-6 . 10.1038/s41598-017-07119-6 . Scientific Reports

Combined in Vivo Amperometric Oximetry and Electrophysiology in a Single Sensor: A Tool for Epilepsy Research

Ana Ledo; Cátia F. Lourenço; João Laranjinha; Greg A. Gerhardt; Rui M. Barbosa, Analytical Chemistry. 2017. https://doi.org/10.1021/acs.analchem.7b03452 . 10.1021/acs.analchem.7b03452 . Analytical Chemistry

Ceramic-Based Multisite Platinum Microelectrode Arrays: Morphological Characteristics and Electrochemical Performance for Extracellular Oxygen Measurements in Brain Tissue

Ana Ledo; Cátia F. Lourenço; João Laranjinha; Christopher M. A. Brett; Greg A. Gerhardt; Rui M. Barbosa, Analytical Chemistry. 1674 - 1683. 3. 89. 2017. https://doi.org/10.1021/acs.analchem.6b03772 . 10.1021/acs.analchem.6b03772 . Analytical Chemistry

Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling

Lourenço, C.F.; Ledo, A.; Barbosa, R.M.; Laranjinha, J., Experimental Neurology. 36 - 43. 291. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85011654048&partnerID=MN8TOARS . 10.1016/j.expneurol.2017.01.013 . Experimental Neurology

Neurovascular-neuroenergetic coupling axis in the brain: master regulation by nitric oxide and consequences in aging and neurodegeneration

Lourenço, C.F.; Ledo, A.; Barbosa, R.M.; Laranjinha, J., Free Radical Biology and Medicine. 668 - 682. 108. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018262522&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2017.04.026 . Free Radical Biology and Medicine

Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation

Dias, C.; Lourenço, C.F.; Ferreiro, E.; Barbosa, R.M.; Laranjinha, J.; Ledo, A., Neurobiology of Aging. 84 - 95. 46. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84978903965&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2016.06.012 . Neurobiology of Aging

Microelectrode array biosensor for high-resolution measurements of extracellular glucose in the brain

Lourenço, C.F.; Ledo, A.; Laranjinha, J.; Gerhardt, G.A.; Barbosa, R.M., Sensors and Actuators, B: Chemical. 298 - 307. 237. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84976594136&partnerID=MN8TOARS . 10.1016/j.snb.2016.06.083 . Sensors and Actuators, B: Chemical

Coupling of ascorbate and nitric oxide dynamics in vivo in the rat hippocampus upon glutamatergic neuronal stimulation: A novel functional interplay.

Ferreira NR; Lourenço CF; Barbosa RM; Laranjinha J, Brain Research Bulletin. 13 - 19. 114:13-9.. 2015. http://europepmc.org/abstract/med/25783673 . 10.1016/j.brainresbull.2015.03.002 . Brain Research Bulletin

Age-associated changes of nitric oxide concentration dynamics in the central nervous system of Fisher 344 rats.

Ledo A; Lourenço CF; Caetano M; Barbosa RM; Laranjinha J, Cellular and Molecular Neurobiology. 1. 35. 2015. http://europepmc.org/abstract/med/25274046 . 10.1007/s10571-014-0115-0 . Cellular and Molecular Neurobiology

Neurovascular and neurometabolic derailment in aging and alzheimer's disease

Lourenço, C.F.; Ledo, A.; Dias, C.; Barbosa, R.M.; Laranjinha, J., Frontiers in Aging Neuroscience. MAY. 7. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84931266835&partnerID=MN8TOARS . 10.3389/fnagi.2015.00103 . Frontiers in Aging Neuroscience

The pattern of glutamate-induced nitric oxide dynamics in vivo and its correlation with nNOS expression in rat hippocampus, cerebral cortex and striatum.

Lourenço CF; Ferreira NR; Santos RM; Lukacova N; Barbosa RM; Laranjinha J, Brain Research. 1 - 11. 1554. 2014. http://europepmc.org/abstract/med/24495843 . 10.1016/j.brainres.2014.01.030 . Brain Research

Neurovascular coupling in hippocampus is mediated via diffusion by neuronal-derived nitric oxide.

Lourenço CF; Santos RM; Barbosa RM; Cadenas E; Radi R; Laranjinha J, Free Radical Biology and Medicine. 421 - 429. 73. 2014. http://europepmc.org/abstract/med/24887095 . 10.1016/j.freeradbiomed.2014.05.021 . Free Radical Biology and Medicine

Self-mixing microprobe for monitoring microvascular perfusion in rat brain

Figueiras, E.; Oliveira, R.; Lourenço, C.F.; Campos, R.; Humeau-Heurtier, A.; Barbosa, R.M.; Laranjinha, J.; Requicha Ferreira, L.F.; De Mul, F.F.M., Medical and Biological Engineering and Computing. 103 - 112. 1-2. 51. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874633368&partnerID=MN8TOARS . 10.1007/s11517-012-0973-x . Medical and Biological Engineering and Computing

Nitric oxide inactivation mechanisms in the brain: Role in bioenergetics and neurodegeneration

Santos, R.M.; Lourenço, C.F.; Ledo, A.; Barbosa, R.M.; Laranjinha, J., International Journal of Cell Biology. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863706810&partnerID=MN8TOARS . 10.1155/2012/391914 . International Journal of Cell Biology

Nitric oxide signaling in the brain: translation of dynamics into respiration control and neurovascular coupling

Laranjinha, João; Santos, Ricardo M.; Lourenço, Cátia F.; Ledo, Ana; Barbosa, Rui M.; Laranjinha, J.; Santos, R.M.; et al, Annals of the New York Academy of Sciences. 10 - 18. 1. 1259. 2012. http://dx.doi.org/10.1111/j.1749-6632.2012.06582.x . 10.1111/j.1749-6632.2012.06582.x . Annals of the New York Academy of Sciences

Brain nitric oxide inactivation is governed by the vasculature

Santos, R.M.; Lourenço, C.F.; Pomerleau, F.; Huettl, P.; Gerhardt, G.A.; Laranjinha, J.; Barbosa, R.M., Antioxidants and Redox Signaling. 1011 - 1021. 6. 14. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79951864475&partnerID=MN8TOARS . 10.1089/ars.2010.3297 . Antioxidants and Redox Signaling

In vivo modulation of nitric oxide concentration dynamics upon glutamatergic neuronal activation in the hippocampus

LourençO, C.F.; Santos, R.; Barbosa, R.M.; Gerhardt, G.; Cadenas, E.; Laranjinha, J., Hippocampus. 622 - 630. 6. 21. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79956360575&partnerID=MN8TOARS . 10.1002/hipo.20774 . Hippocampus

Evidence for a pathway that facilitates nitric oxide diffusion in the brain.

Santos RM; Lourenço CF; Gerhardt GA; Cadenas E; Laranjinha J; Barbosa RM, Neurochemistry International. 90 - 96. 1. 59. 2011. http://europepmc.org/abstract/med/21672575 . 10.1016/j.neuint.2011.05.016 . Neurochemistry International

Cyclosporine A-induced nitration of tyrosine 34 MnSOD in endothelial cells: role of mitochondrial superoxide.

Redondo-Horcajo M; Romero N; Martínez-Acedo P; Martínez-Ruiz A; Quijano C; Lourenço CF; Movilla N; et al, Cardiovascular Research. 356 - 365. 2. 87. 2010. http://europepmc.org/abstract/med/20106845 . 10.1093/cvr/cvq028 . Cardiovascular Research

A comparative study of carbon fiber-based microelectrodes for the measurement of nitric oxide in brain tissue

Santos, R.M.; Lourenço, C.F.; Piedade, A.P.; Andrews, R.; Pomerleau, F.; Huettl, P.; Gerhardt, G.A.; Laranjinha, J.; Barbosa, R.M., Biosensors and Bioelectronics. 704 - 709. 4. 24. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-53049092283&partnerID=MN8TOARS . 10.1016/j.bios.2008.06.034 . Biosensors and Bioelectronics

LDL isolated from plasma-loaded red wine procyanidins resist lipid oxidation and tocopherol depletion

Lourenço, C.F.; Gago, B.; Barbosa, R.M.; De Freitas, V.; Laranjinha, J., Journal of Agricultural and Food Chemistry. 3798 - 3804. 10. 56. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-45549089760&partnerID=MN8TOARS . 10.1021/jf0733259 . Journal of Agricultural and Food Chemistry

Dietary flavonoids with a catechol structure increase a-tocopherol in rats and protect the vitamin from oxidation in vitro1

Frank, J.; Budek, A.; Lundh, T.; Parker, R.S.; Swanson, J.E.; Lourenço, C.F.; Gago, B.; et al, Journal of Lipid Research. 2718 - 2725. 12. 47. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845570860&partnerID=MN8TOARS . 10.1194/jlr.M600291-JLR200 . Journal of Lipid Research

Effects of natural prenylated flavones in the phenotypical ER (+) MCF-7 and ER (-) MDA-MB-231 human breast cancer cells

Pedro, M.; Lourenço, C.F.; Cidade, H.; Kijjoa, A.; Pinto, M.; Nascimento, M.S.J., Toxicology Letters. 24 - 36. 1. 164. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646096970&partnerID=MN8TOARS . 10.1016/j.toxlet.2005.11.007 . Toxicology Letters