Publications
Information about journal articles, updated at 06-09-2026, from platform CIÊNCIAVITAE.
Leucine-rich repeat kinase 2 impairs the release sites of Parkinson’s disease vulnerable dopamine axons
Chen, Chuyu; He, Qianzi; Tombesi, Giulia; Napier, Eve; Jaconelli, Matthew; Moreno-Ramos, Oscar Andrés; Serio, Hannah; et al, Nature Communications. 1. 17. 2026. https://doi.org/10.1038/s41467-026-75194-3 . 10.1038/s41467-026-75194-3 . Nature Communications
LRRK2 regulates synaptic function through modulation of actin cytoskeletal dynamics
Giulia Tombesi; Shiva Kompella; Giulia Favetta; Chuyu Chen; Marta Ornaghi; Yibo Zhao; Ester Morosin; et al, eLife. 2026. https://doi.org/10.7554/eLife.95987.4 . 10.7554/eLife.95987.4 . eLife
LRRK2 and the fragile synapse: a molecular prelude to Parkinson’s disease?
Beatrice Masotti; Giulia Tombesi; Loukia Parisiadou; Elisa Greggio, Biochemical Journal. 2025. https://doi.org/10.1042/BCJ20253351 . 10.1042/BCJ20253351 . Biochemical Journal
LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons
Chuyu Chen; Meghan Masotti; Nathaniel Shepard; Vanessa Promes; Giulia Tombesi; Daniel Arango; Claudia Manzoni; et al, Molecular Psychiatry. 2025. https://doi.org/10.1038/s41380-025-03030-z . 10.1038/s41380-025-03030-z . Molecular Psychiatry
PAK6-mediated phosphorylation of PPP2R2C regulates LRRK2-PP2A complex formation
Iannotta, Lucia; Emanuele, Marco; Favetta, Giulia; Tombesi, Giulia; Vandewynckel, Laurine; Lara Ordóñez, Antonio Jesús; Saliou, Jean-Michel; et al, Frontiers in Molecular Neuroscience. 16. 2023. https://doi.org/10.3389/fnmol.2023.1269387 . 10.3389/fnmol.2023.1269387 . published Frontiers in Molecular Neuroscience
Cortical, Striatal and Dopaminergic Neurons Cultures Protocol
Giulia Tombesi, protocols.io. 2023. https://www.protocols.io/view/cortical-striatal-and-dopaminergic-neurons-culture-cwbsxane . dx.doi.org/10.17504/protocols.io.rm7vzxn48gx1/v1 . protocols.io
Genotyping protocol for mice
Giulia Tombesi, protocols.io. 2023. https://www.protocols.io/view/genotyping-protocol-for-mice-cwbyxapw . dx.doi.org/10.17504/protocols.io.kxygx3mjwg8j/v1 . protocols.io
Duodenal alpha-Synuclein Pathology and Enteric Gliosis in Advanced Parkinson's Disease.
Aron Emmi; Michele Sandre; FRANCESCO PAOLO RUSSO; Tombesi G; Garrì F; Marta Campagnolo; Carecchio M; et al, Movement disorders : official journal of the Movement Disorder Society. 2023. https://doi.org/10.1002/mds.29358 . 10.1002/mds.29358 . Movement disorders : official journal of the Movement Disorder Society
Immunocytochemistry of primary neurons
Giulia Tombesi, protocols.io. 2023. https://www.protocols.io/view/immunocytochemistry-of-primary-neurons-cwbpxamn . dx.doi.org/10.17504/protocols.io.eq2lyjdkmlx9/v1 . protocols.io
Human frataxin, the Friedreich ataxia deficient protein, interacts with mitochondrial respiratory chain
Davide Doni; Federica Cavion; Marco Bortolus; Elisa Baschiera; Silvia Muccioli; Giulia Tombesi; Federica d’Ettorre; et al, Cell Death & Disease. 2023. http://dx.doi.org/10.1038/s41419-023-06320-y . 10.1038/s41419-023-06320-y . Cell Death & Disease
Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues
Iannotta, L.; Biosa, A.; Kluss, J.H.; Tombesi, G.; Kaganovich, A.; Cogo, S.; Plotegher, N.; et al, Cells. 11. 9. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85094861674&partnerID=MN8TOARS . 10.3390/cells9112344 . Cells
An agonist of the CXCR4 receptor strongly promotes regeneration of degenerated motor axon terminals
Negro, S.; Zanetti, G.; Mattarei, A.; Valentini, A.; Megighian, A.; Tombesi, G.; Zugno, A.; et al, Cells. 10. 8. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075177963&partnerID=MN8TOARS . 10.3390/cells8101183 . Cells
5 12 out of 12 Publications
All projects
Information of exclusive responsibility of the researcher 06-09-2026 , from platform CIÊNCIAVITAE.
2023/01 - 2024/12
Redefining Parkinson’s Disease Pathophysiology Mechanisms in the Context of Heterogeneous Substantia Nigra Neuron Subtypes
ASAP
Post-doc Fellow
2022/01 - 2022/03
Ruolo della proteina LRRK2 nel rimodellamento delle spine dendritiche
BIRD 2021 - PRID SEED
Post-doc Fellow
2022/05 - 2022/11
GBA stabilization and activation through nanobodies and derived peptide mimetics in neuronal models
MJFF 2021_ GRANT ID MJFF-020706
Post-doc Fellow
2018/10 - 2021/12
LRRKing - Role of the Parkinson’s disease kinase LRRK2 in shaping neurites and synapses
STARS-2017-CoG
PhD Student Fellow
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