Henrique Girão

LAMP2A regulates the loading of proteins into exosomes

Ferreira JV; Soares, AR; Ramalho, J; Carvalho, CM; Cardoso, MH; Pintado, P; Carvalho, AS; et al, Science Advances . 2022. accepted Science Advances

Phagolysosomal remodeling to confine C. albicans in macrophage

Domingues, Neuza; Gonçalves, Teresa; Girao, Henrique, Trends in Microbiology. 2022. accepted Trends in Microbiology

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

van der Velden, Jolanda; Asselbergs, Folkert W; Bakkers, Jeroen; Batkai, Sandor; Bertrand, Luc; Bezzina, Connie R; Bot, Ilze; et al, Cardiovascular Research. 2022. Cardiovascular Research

Microglial Extracellular Vesicles as Vehicles for Neurodegeneration Spreading

Aires, Inês Dinis; Ribeiro-Rodrigues, Teresa; Boia, Raquel; Ferreira-Rodrigues, Magda; Girão, Henrique; Ambrósio, António Francisco; Santiago, Ana Raquel, Biomolecules. 6. 11. 2021. Biomolecules

COVID-19-related cardiac complications from clinical evidences to basic mechanisms: opinion paper of the ESC Working Group on Cellular Biology of the Heart

Pesce, Maurizio; Agostoni, Piergiuseppe; Bøtker, Hans-Erik; Brundel, Bianca; Davidson, Sean M; Caterina, Raffaele De; Ferdinandy, Peter; et al, Cardiovascular Research. 2148 - 2160. 10. 117. 2021. Cardiovascular Research

Cardiac phospholipidome is altered during ischemia and reperfusion in an ex vivo rat model

Montero-Bullon, Javier-Fernando; Aveiro, Susana S.; Melo, Tânia; Martins-Marques, Tânia; Lopes, Diana; Neves, Bruna; Girão, Henrique; Rosário M Domingues, M.; Domingues, Pedro, Biochemistry and Biophysics Reports. 27. 2021. Biochemistry and Biophysics Reports

IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria: guidelines of the EU-CARDIOPROTECTION COST Action

Lecour, Sandrine; Andreadou, Ioanna; Bøtker, Hans Erik; Davidson, Sean M.; Heusch, Gerd; Ruiz-Meana, Marisol; Schulz, Rainer; et al, Basic Research in Cardiology. 1. 116. 2021. Basic Research in Cardiology

Immune cell subsets as a marker of development of heart failure: The application of bioinformatics tools

Abreu, Mónica Teresa; Baptista, Rui; Girão, Henrique, Revista Portuguesa de Cardiologia (English Edition). 849 - 851. 11. 40. 2021. Revista Portuguesa de Cardiologia (English Edition)

Cellular crosstalk in cardioprotection: where and when do reactive oxygen species play a role?

Martins-Marques, Tania; Rodriguez-Sinovas, Antonio; Girao, Henrique, Free Radical Biology and Medicine. 2021. Free Radical Biology and Medicine

A novel cardioprotective strategy targeting mitochondrial reactive oxygen species production independent of antioxidant activity (Editorial Comment)

Girão, Henrique; Martins-Marques, Tania, Revista Portuguesa de Cardiologia. 2021. Revista Portuguesa de Cardiologia

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky; Amal Kamal Abdel-Aziz; Sara Abdelfatah; (...); Girao, Henrique, Autophagy. 2021. Autophagy

The Role of Essential Oils and Their Main Compounds in the Management of Cardiovascular Disease Risk Factors

Alves-Silva, Jorge M.; Zuzarte, Mónica; Girão, Henrique; Salgueiro, Lígia, Molecules. 12. 26. 2021. Molecules

Mitochondrial ion channels as targets for cardioprotection

Hausenloy, Derek; Schulz R; Girao, Henrique; Kwak, Brenda R.; De Stefani D; Rosario Rizzuto R; Bernardi P; Di Lisa F, Journal of Cellular and Molecular Medicine (accepted for publication). 2020. Journal of Cellular and Molecular Medicine (accepted for publication)

Targeting mitochondrial fusion and fission proteins for cardioprotection

Hernandez-Resendiz S; Prunier F; Girao, Henrique; Dorn G; Hausenloy, Derek, J Cell Mol Med (accepted for publication). 2020. J Cell Mol Med (accepted for publication)

Ischaemia impacts on TNT-mediated communication between cardiac cells

Batista-Almeida, Daniela; Ribeiro-Rodrigues, Teresa; Martins-Marques, Tânia; Cortes, Luisa; Antunes, Manuel J; Antunes, Pedro E; Gonçalves, Lino; et al, Current Research in Cell Biology (accepted for publication). 2020. Current Research in Cell Biology (accepted for publication)

EHD1 Modulates Cx43 Gap Junction Remodeling Associated with Cardiac Diseases

Martins-Marques, Tânia; Catarino, Steve; Gonçalves, Alexandre; Miranda-Silva, Daniela; Gonçalves, Lino M; Antunes, Pedro E; Coutinho, Gonçalo Freitas; et al, Circulation Research. 2020. Circulation Research

A Conserved LIR Motif in Connexins Mediates Ubiquitin-Independent Binding to LC3/GABARAP Proteins

Catarino, Steve; Ribeiro-Rodrigues, Teresa M; Sá Ferreira, Rita; Ramalho, José; Abert, Christine; Martens, Sascha; Girão, Henrique, Cells. 4. 9. 2020. Cells

Intercellular Communication in the Heart: Therapeutic Opportunities for Cardiac Ischemia

Martins-Marques, Tania; Hausenloy, Derek J.; Sluijter, Joost P.G.; Leybaert, Luc; Girao, Henrique, Trends in Molecular Medicine. 2020. Trends in Molecular Medicine

Myocardial infarction affects Cx43 content of extracellular vesicles secreted by cardiomyocytes

Martins-Marques, Tania; Ribeiro-Rodrigues, Teresa; de Jager, Saskia C; Zuzarte, Monica; Ferreira, Cátia; Cruz, Pedro; Reis, Liliana; et al, Life Science Alliance. 12. 3. 2020. Life Science Alliance

A new predictive marker of ventricular remodeling associated with aortic stenosis

Girão, Henrique, Revista Portuguesa de Cardiologia. 389 - 390. 7. 39. 2020. Revista Portuguesa de Cardiologia

Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells

Tishchenko, Alexander; Azorín, Daniel D.; Vidal-Brime, Laia; Muñoz, María José; Arenas, Pol Jiménez; Pearce, Christopher; Girao, Henrique; Ramón y Cajal, Santiago; Aasen, Trond, Cancers. 10. 12. 2020. Cancers

Simple and Fast SEC-Based Protocol to Isolate Human Plasma-Derived Extracellular Vesicles for Transcriptional Research

Gaspar, Laetitia S.; Santana, Magda M.; Henriques, Carina; Pinto, Maria M.; Ribeiro-Rodrigues, Teresa M.; Girão, Henrique; Nobre, Rui Jorge; Pereira de Almeida, Luís, Molecular Therapy - Methods & Clinical Development. 723 - 737. 18. 2020. Molecular Therapy - Methods & Clinical Development

Canonical and Non-Canonical Roles of Connexin43 in Cardioprotection

Rusiecka, Olga M.; Montgomery, Jade; Morel, Sandrine; Batista-Almeida, Daniela; Van Campenhout, Raf; Vinken, Mathieu; Girao, Henrique; Kwak, Brenda R., Biomolecules. 9. 10. 2020. Biomolecules

Exosomes derived from microglia exposed to elevated pressure amplify the neuroinflammatory response in retinal cells

Aires, Inês Dinis; Ribeiro-Rodrigues, Teresa; Boia, Raquel; Catarino, Steve; Girão, Henrique; Ambrósio, António Francisco; Santiago, Ana Raquel, Glia. 2705 - 2724. 12. 68. 2020. Glia

Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart

Perrino, Cinzia; Ferdinandy, Péter; Bøtker, Hans E; Brundel, Bianca J J M; Collins, Peter; Davidson, Sean M; den Ruijter, Hester M; et al, Cardiovascular Research. 367 - 385. 2. 117. 2020. Cardiovascular Research

Micro-RNA Analysis in Pulmonary Arterial Hypertension

Santos-Ferreira, Cátia A.; Abreu, Mónica T.; Marques, Carla I.; Gonçalves, Lino M.; Baptista, Rui; Girão, Henrique M., JACC: Basic to Translational Science. 1149 - 1162. 11. 5. 2020. JACC: Basic to Translational Science

Chemical characterization and cytotoxic potential of an ellagitannin-enriched fraction from Fragaria vesca leaves

Liberal, Joana; Costa, Gustavo; Carmo, Anália; Vitorino, Rui; Marques, Carla; Domingues, Maria Rosário; Domingues, Pedro; et al, Arabian Journal of Chemistry. 3652 - 3666. 8. 12. 2019. Arabian Journal of Chemistry

Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis

Ferreira, Joao Vasco; Rosa Soares, Ana; Ramalho, José S.; Ribeiro-Rodrigues, Teresa; Máximo, Catarina; Zuzarte, Mónica; Girão, Henrique; Pereira, Paulo, PLOS ONE. 10. 14. 2019. PLOS ONE

Ischaemia alters the effects of cardiomyocyte-derived extracellular vesicles on macrophage activation

Almeida Paiva, R.; Martins-Marques, T.; Jesus, K.; Ribeiro-Rodrigues, T.; Zuzarte, M.; Silva, A.; Reis, L.; et al, Journal of Cellular and Molecular Medicine. 1137 - 1151. 2. 23. 2019. Journal of Cellular and Molecular Medicine

RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes

Lissoni, Alessio; Hulpiau, Paco; Martins-Marques, Tânia; Wang, Nan; Bultynck, Geert; Schulz, Rainer; Witschas, Katja; et al, Cardiovascular Research. 2019. Cardiovascular Research

PROTEOSTASIS: A European Network to Break Barriers and Integrate Science on Protein Homeostasis

Dissmeyer, Nico; Coux, Olivier; Rodriguez, Manuel S.; Barrio, Rosa, Trends in Biochemical Sciences. 383 - 387. 5. 44. 2019. Trends in Biochemical Sciences

Biological Functions of Connexin43 Beyond Intercellular Communication

Martins-Marques, Tania; Ribeiro-Rodrigues, Teresa; Batista-Almeida, Daniela; Aasen, Trond; Kwak, Brenda R.; Girao, Henrique, Trends in Cell Biology. 835 - 847. 10. 29. 2019. Trends in Cell Biology

Elucidation of the dynamic nature of interactome networks: A practical tutorial

Anjo, Sandra I.; Martins-Marques, Tania; Pereira, Paulo; Girão, Henrique; Manadas, Bruno, Journal of Proteomics. 116 - 126. 171. 2018. Journal of Proteomics

Circulating blood cells and extracellular vesicles in acute cardioprotection

Davidson, Sean M; Andreadou, Ioanna; Barile, Lucio; Birnbaum, Yochai; Cabrera-Fuentes, Hector A; Cohen, Michael V; Downey, James M; et al, Cardiovascular Research. 1156 - 1166. 7. 115. 2018. Cardiovascular Research

Disclosing the functional changes of two genetic alterations in a patient with Chronic Progressive External Ophthalmoplegia: Report of the novel mtDNA m.7486G>A variant

Bacalhau, Mafalda; Simões, Marta; Rocha, Mariana C.; Hardy, Steven A.; Vincent, Amy E.; Durães, João; Macário, Maria C.; et al, Neuromuscular Disorders. 350 - 360. 4. 28. 2018. Neuromuscular Disorders

Intravascular imaging, histopathological analysis, and catecholamine quantification following catheter-based renal denervation in a swine model: the impact of prebifurcation energy delivery

Delgado-Silva, J.; Fernandes, R.; Pita, I.R.; Pereira, F.C.; Jaguszewski, M.; Gutiérrez-Chico, J.L.; Ribeiro-Rodrigues, T.; et al, Hypertension Research. 708 - 717. 9. 41. 2018. Hypertension Research

Realizing the therapeutic potential of novel cardioprotective therapies: The EU-CARDIOPROTECTION COST Action - CA16225

Andreadou, Ioanna; (...); Girao, Henrique; Hausenloy, Derek, Conditioning Medicine. 3. 1. 2018. Conditioning Medicine

Signalling mechanisms that regulate metabolic profile and autophagy of acute myeloid leukaemia cells

Pereira, Olga; Teixeira, Alexandra; Marques, Maria Belém Sousa Sampaio; Castro, Isabel; Girão, Henrique; Ludovico, Paula; Pereira, O.; et al, Journal of Cellular and Molecular Medicine. 4807 - 4817. 10. 22. 2018. Journal of Cellular and Molecular Medicine

Cardiac-released extracellular vesicles can activate endothelial cells

Deddens, Janine C.; Vrijsen, Krijn R.; Girao, Henrique; Doevendans, Pieter A.; Sluijter, Joost P. G., Annals of Translational Medicine. 64 - 64. 3. 5. 2017. Annals of Translational Medicine

Characterization of phospholipid nitroxidation by LC-MS in biomimetic models and in H9c2 Myoblast using a lipidomic approach

Melo, Tânia; Domingues, Pedro; Ribeiro-Rodrigues, Teresa M.; Girão, Henrique; Segundo, Marcela A.; Domingues, M. Rosário M., Free Radical Biology and Medicine. 219 - 227. 106. 2017. Free Radical Biology and Medicine

Hyperglycemia-induced degradation of HIF-1a contributes to impaired response of cardiomyocytes to hypoxia

Ramalho, Ana Rita; Toscano, Adriana; Pereira, Paulo; Girão, Henrique; Gonçalves, Lino; Marques, Carla, Revista Portuguesa de Cardiologia. 367 - 373. 5. 36. 2017. Revista Portuguesa de Cardiologia

The Expression of Connexins and SOX2 Reflects the Plasticity of Glioma Stem-Like Cells

Balça-Silva, Joana; Matias, Diana; Dubois, Luiz Gustavo; Carneiro, Brenno; do Carmo, Anália; Girão, Henrique; Ferreira, Fernanda; et al, Translational Oncology. 555 - 569. 4. 10. 2017. Translational Oncology

Molecular control of chaperone-mediated autophagy

Catarino, S.; Pereira, P.; Girao, H., Essays in Biochemistry. 663 - 674. 6. 61. 2017. Essays in Biochemistry

Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis

Ribeiro-Rodrigues, Teresa M.; Laundos, Tiago L.; Pereira-Carvalho, Rita; Batista-Almeida, Daniela; Pereira, Ricardo; Coelho-Santos, Vanessa; Silva, Ana P.; et al, Cardiovascular Research. 1338 - 1350. 11. 113. 2017. Cardiovascular Research

MicroRNA-424(322) as a new marker of disease progression in pulmonary arterial hypertension and its role in right ventricular hypertrophy by targeting SMURF1

Baptista, Rui; Marques, Carla; Catarino, Steve; Enguita, Francisco J; Costa, Marina C; Matafome, Paulo; Zuzarte, Mónica; et al, Cardiovascular Research. 53 - 64. 1. 114. 2017. Cardiovascular Research

Glioblastoma entities express subtle differences in molecular composition and response to treatment

Balça-Silva, Joana; Matias, Diana; Do Carmo, Anália; Dubois, Luiz Gustavo; Gonçalves, Ana Cristina; Girão, Henrique; Silva Canedo, Nathalie Henriques; et al, Oncology Reports. 1341 - 1352. 3. 38. 2017. Oncology Reports

Role of connexin 43 in different forms of intercellular communication – gap junctions, extracellular vesicles and tunnelling nanotubes

Teresa M. Ribeiro-Rodrigues; Tânia Martins-Marques; Sandrine Morel; Brenda R. Kwak; Henrique Girão, Journal of Cell Science. 3619 - 3630. 21. 130. 2017. Journal of Cell Science

The role of galectin-1 in in vitro and in vivo photodynamic therapy with a galactodendritic porphyrin

Pereira, Patrícia M.R.; Silva, Sandrina; Ramalho, José S.; Gomes, Célia M.; Girão, Henrique; Cavaleiro, José A.S.; Ribeiro, Carlos A.F.; Tomé, João P.C.; Fernandes, Rosa, European Journal of Cancer. 60 - 69. 68. 2016. European Journal of Cancer

Mitochondria-Targeted Photodynamic Therapy with a Galactodendritic Chlorin to Enhance Cell Death in Resistant Bladder Cancer Cells

Pereira, Patrícia M. R.; Silva, Sandrina; Bispo, Mafalda; Zuzarte, Mónica; Gomes, Célia; Girão, Henrique; Cavaleiro, José A. S.; et al, Bioconjugate Chemistry. 2762 - 2769. 11. 27. 2016. Bioconjugate Chemistry

Proteostasis and SUMO in the heart

Da Silva-Ferrada, Elisa; Ribeiro-Rodrigues, Teresa M.; Rodríguez, Manuel S.; Girão, Henrique, The International Journal of Biochemistry & Cell Biology. 443 - 450. 79. 2016. The International Journal of Biochemistry & Cell Biology

Alteration in Phospholipidome Profile of Myoblast H9c2 Cell Line in a Model of Myocardium Starvation and Ischemia.

Girao, Henrique, Journal of cellular physiology. 2016. Journal of cellular physiology

One small step for exosomes, one giant leap for Kawasaki disease

Girão, Henrique, Revista Portuguesa de Cardiologia. 275 - 276. 5. 35. 2016. Revista Portuguesa de Cardiologia

Acetylated bacterial cellulose coated with urinary bladder matrix as a substrate for retinal pigment epithelium

Gonçalves, Sara; Rodrigues, Inês Patrício; Padrão, Jorge; Silva, João Pedro; Sencadas, Vitor; Lanceros-Mendez, Senentxu; Girão, Henrique; et al, Colloids and Surfaces B: Biointerfaces. 1 - 9. 139. 2016. Colloids and Surfaces B: Biointerfaces

Protective Effects of Terpenes on the Cardiovascular System: Current Advances and Future Perspectives

M. Alves-Silva, Jorge; Zuzarte, Monica; Marques, Carla; Salgueiro, Ligia; Girao, Henrique, Current Medicinal Chemistry. 4559 - 4600. 40. 23. 2016. Current Medicinal Chemistry

Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin

Martins-Marques, Tania; Pinho, Maria Joao; Zuzarte, Monica; Oliveira, Carla; Pereira, Paulo; Sluijter, Joost P. G.; Gomes, Celia; Girao, Henrique, Journal of Extracellular Vesicles. 1. 5. 2016. Journal of Extracellular Vesicles

Heart ischemia results in connexin43 ubiquitination localized at the intercalated discs

Martins-Marques, Tânia; Catarino, Steve; Marques, Carla; Matafome, Paulo; Ribeiro-Rodrigues, Teresa; Baptista, Rui; Pereira, Paulo; Girão, Henrique, Biochimie. 196 - 201. 112. 2015. Biochimie

Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes

Martins-Marques, Tania; Catarino, Steve; Zuzarte, Monica; Marques, Carla; Matafome, Paulo; Pereira, Paulo; Girão, Henrique, Biochemical Journal. 231 - 245. 2. 467. 2015. Biochemical Journal

Tamoxifen in combination with temozolomide induce a synergistic inhibition of PKC-pan in GBM cell lines

Balça-Silva, Joana; Matias, Diana; do Carmo, Anália; Girão, Henrique; Moura-Neto, Vivaldo; Sarmento-Ribeiro, Ana Bela; Lopes, Maria Celeste, Biochimica et Biophysica Acta (BBA) - General Subjects. 722 - 732. 4. 1850. 2015. Biochimica et Biophysica Acta (BBA) - General Subjects

Connexin 43 ubiquitination determines the fate of gap junctions: restrict to survive

Ribeiro-Rodrigues, Teresa M.; Catarino, Steve; Pinho, Maria J.; Pereira, Paulo; Girao, Henrique, Biochemical Society Transactions. 471 - 475. 3. 43. 2015. Biochemical Society Transactions

Bacterial Cellulose As a Support for the Growth of Retinal Pigment Epithelium

Gonçalves, Sara; Padrão, Jorge; Rodrigues, Inês Patrício; Silva, João Pedro; Sencadas, Vítor; Lanceros-Mendez, Senentxu; Girão, Henrique; Dourado, Fernando; Rodrigues, Lígia R., Biomacromolecules. 1341 - 1351. 4. 16. 2015. Biomacromolecules

The Force at the Tip - Modelling Tension and Proliferation in Sprouting Angiogenesis

Santos-Oliveira, Patrícia; Correia, António; Rodrigues, Tiago; Ribeiro-Rodrigues, Teresa M; Matafome, Paulo; Rodríguez-Manzaneque, Juan Carlos; Seiça, Raquel; Girão, Henrique; Travasso, Rui D. M., PLOS Computational Biology. 8. 11. 2015. PLOS Computational Biology

Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart

Tania Martins-Marques; Sandra Isabel Anjo; Paulo Pereira; Bruno Manadas; Henrique Girão, Molecular & Cellular Proteomics. 3040 - 3055. 11. 14. 2015. Molecular & Cellular Proteomics

To beat or not to beat: degradation of Cx43 imposes the heart rhythm

Martins-Marques, Tânia; Catarino, Steve; Marques, Carla; Pereira, Paulo; Girão, Henrique, Biochemical Society Transactions. 476 - 481. 3. 43. 2015. Biochemical Society Transactions

Autophagy and Ubiquitination in Cardiovascular Diseases

Martins-Marques, Tania; Ribeiro-Rodrigues, Teresa; Pereira, Paulo; Codogno, Patrice; Girao, Henrique, DNA and Cell Biology. 243 - 251. 4. 34. 2015. DNA and Cell Biology

K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy

Vasco Ferreira, Joao; Rosa Soares, Ana; Silva Ramalho, Jose; Pereira, Paulo; Girao, Henrique, Scientific Reports. 1. 5. 2015. Scientific Reports

Cholinergic stimulation with pyridostigmine protects myocardial infarcted rats against ischemic-induced arrhythmias and preserves connexin43 protein

Santos-Almeida, Fernanda Machado; Girão, Henrique; da Silva, Carlos Alberto Aguiar; Salgado, Helio Cesar; Fazan, Rubens, American Journal of Physiology-Heart and Circulatory Physiology. H101 - H107. 2. 308. 2015. American Journal of Physiology-Heart and Circulatory Physiology

Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells

Soares, Ana Rosa; Martins-Marques, Tania; Ribeiro-Rodrigues, Teresa; Ferreira, Joao Vasco; Catarino, Steve; Pinho, Maria João; Zuzarte, Monica; et al, Scientific Reports. 1. 5. 2015. Scientific Reports

New platinum(II)–bipyridyl corrole complexes: Synthesis, characterization and binding studies with DNA and HSA

Iglesias, Bernardo A.; Barata, Joana F.B.; Pereira, Patrícia M.R.; Girão, Henrique; Fernandes, Rosa; Tomé, João P.C.; Neves, Maria G.P.M.S.; Cavaleiro, José A.S., Journal of Inorganic Biochemistry. 32 - 41. 153. 2015. Journal of Inorganic Biochemistry

Synthesis, characterization and biomolecule-binding properties of novel tetra-platinum(ii)-thiopyridylporphyrins

Lourenço, Leandro M. O.; Iglesias, Bernardo A.; Pereira, Patrícia M. R.; Girão, Henrique; Fernandes, Rosa; Neves, Maria G. P. M. S.; Cavaleiro, José A. S.; Tomé, João P. C., Dalton Transactions. 530 - 538. 2. 44. 2015. Dalton Transactions

AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions

Ribeiro-Rodrigues, Teresa M.; Catarino, Steve; Marques, Carla; Ferreira, João V.; Martins-Marques, Tânia; Pereira, Paulo; Girão, Henrique, The FASEB Journal. 4629 - 4641. 11. 28. 2014. The FASEB Journal

iTRAQ-based proteomic analysis of ellagitannins-enriched fraction from Fragaria vesca leaves on HepG2 cells

Liberal, J; Costa, G; Marques, C; Girão, H; Vitorino, R; Domingues, R; Domingues, P; Cruz, MT; Batista, MT, Planta Medica. 1438 - 1438. 16. 80. 2014. Planta Medica

Bioactivity of Fragaria vesca leaves through inflammation, proteasome and autophagy modulation

Liberal, Joana; Francisco, Vera; Costa, Gustavo; Figueirinha, Artur; Amaral, Maria Teresa; Marques, Carla; Girão, Henrique; et al, Journal of Ethnopharmacology. 113 - 122. 158. 2014. Journal of Ethnopharmacology

STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy

Ferreira, J.V.; Fofo, H.; Bejarano, E.; Bento, C.F.; Ramalho, J.S.; Girao, H.; Pereira, P., Autophagy. 1349 - 1366. 9. 9. 2013. Autophagy

DNAJB4 molecular chaperone distinguishes WT from mutant E-cadherin, determining their fate in vitro and in vivo

Simões-Correia, Joana; Silva, Diana I.; Melo, Soraia; Figueiredo, Joana; Caldeira, Joana; Pinto, Marta T.; Girão, Henrique; Pereira, Paulo; Seruca, Raquel, Human Molecular Genetics. 2094 - 2105. 8. 23. 2013. Human Molecular Genetics

Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner

Bejarano, E.; Girao, H.; Yuste, A.; Patel, B.; Marques, C.; Spray, D.C.; Pereira, P.; Cuervo, A.M., Molecular Biology of the Cell. 2156 - 2169. 11. 23. 2012. Molecular Biology of the Cell

Ubiquitin-mediated internalization of connexin43 is independent of the canonical endocytic tyrosine-sorting signal

Catarino, S.; Ramalho, J.S.; Marques, C.; Pereira, P.; Girão, H., Biochemical Journal. 255 - 267. 2. 437. 2011. Biochemical Journal

Eps15 interacts with ubiquitinated Cx43 and mediates its internalization

Girão, H.; Catarino, S.; Pereira, P., Experimental Cell Research. 3587 - 3597. 20. 315. 2009. Experimental Cell Research

Actin in the endocytic pathway: From yeast to mammals

Girao, H.; Geli, M.-I.; Idrissi, F.-Z., FEBS Letters. 2112 - 2119. 14. 582. 2008. FEBS Letters

The proteasome regulates the interaction between Cx43 and ZO-1

Girão, Henrique; Pereira, Paulo; Girao, H.; Pereira, P., Journal of Cellular Biochemistry. 719 - 728. 3. 102. 2007. Journal of Cellular Biochemistry

Subcellular redistribution of components of the ubiquitin-proteasome pathway during lens differentiation and maturation

Girão, Henrique; Pereira, Paulo; Taylor, Allen; Shang, Fu; Girão, H.; Pereira, P.; Taylor, A.; Shang, F., Investigative Ophthalmology and Visual Science. 1386 - 1392. 4. 46. 2005. Investigative Ophthalmology and Visual Science

7-Ketocholesterol Modulates Intercellular Communication Through Gap-Junction in Bovine Lens Epithelial Cells

Girão, Henrique; Catarino, Steve; Pereira, Paulo, Cell Communication and Signaling. 1. 2. 2004. Cell Communication and Signaling

High glucose down-regulates intercellular communication in retinal endothelial cells by enhancing degradation of connexin 43 by a proteasome-dependent mechanism

Fernandes, Rosa; Girão, Henrique; Pereira, Paulo; Fernandes, R.; Girão, H.; Pereira, P., Journal of Biological Chemistry. 27219 - 27224. 26. 279. 2004. Journal of Biological Chemistry

7-Ketocholesterol stimulates differentiation of lens epithelial cells

Girão, H.; Shang, F.; Pereira, P., Molecular Vision. 497 - 501. 9. 2003. Molecular Vision

Phosphorylation of connexin 43 acts as a stimuli for proteasome-dependent degradation of the protein in lens epithelial cells

Henrique Girao; Paulo Pereira, Molecular Vision. 24 - 30. 9. 2003. Molecular Vision

Cholesterol oxides mediated changes in cytoskeletal organisation involves Rho GTPases

Girão, H.; Pereira, P.; Ramalho, J.; Quinlan, R.; Prescott, A., Experimental Cell Research. 502 - 513. 2. 291. 2003. Experimental Cell Research

Lens fibers have a fully functional ubiquitin-proteasome pathway

Pereira, P.; Shang, F.; Hobbs, M.; Girão, H.; Taylor, A.; Pereira, Paulo; Shang, Fu; et al, Experimental Eye Research. 623 - 631. 5. 76. 2003. Experimental Eye Research

Degradation of connexin 43 by ubiquitin-proteasome pathway in the lens

Paulo Pereira; Girao, Henrique, Investigative Opthalmology & Visual Science. suppl S. 42. 2001. Investigative Opthalmology & Visual Science

Effect of cholesterol oxides in ubiquitin conjugation in the lens

Girao, Henrique; Paulo, P., Investigative Ophthalmology & Visual Science. 2001. Investigative Ophthalmology & Visual Science

Cholesterol may act as an antioxidant in lens membranes

Girao, H.; Mota, C.; Pereira, P., Current Eye Research. 448 - 454. 6. 18. 1999. Current Eye Research

Cholesterol oxides accumulate in human cataracts

Girão, H.; Mota, M.C.; Ramalho, J.; Pereira, P., Experimental Eye Research. 645 - 652. 5. 66. 1998. Experimental Eye Research

Cholesterol may cooperate with vitamin E in the antioxidant protection of human lenses

Girao, Henrique; Pereira, P.; Ramalho, JS; Mota, MC, Investigative Ophthalmology & Visual Science. 1997. Investigative Ophthalmology & Visual Science

Cholesterol oxidation in lens membranes: Implications on cataract development

Girao, Henrique; Paulo Pereira; JS Ramalho; MC Mota, Investigative Ophthalmology & Visual Science. 1996. Investigative Ophthalmology & Visual Science

Cholesterol may modulate membrane susceptibility to oxidation in cataractous lens

Girao, H; Pereira, P.; Ramalho, JS; Mota, MC, Vision Research. 1. 35. 1995. Vision Research