Publications
Information about journal articles, updated at 14-05-2024, from platform CIÊNCIAVITAE.
The NDR/LATS protein kinases in neurobiology: key regulator of cell proliferation, differentiation and migration in the ocular and central nervous system
Léger, Hélène; Santos, Paulo Fernando Martins dos, European Journal of Cell Biology. 2023. under revision European Journal of Cell Biology
Grandma's stress programs transgenerational transmission of hippocampal glutamatergic synaptopathy associated with stress-related responses
Morley-Fletcher, Sara; Marrocco, Jordan; Leger, Helène; Mairesse, Jerome; Reynaert, Marie-Line; Van Camp, Gilles; Bouwalerh, Hammou; et al, Psychoneuroendocrinology. 107. 2019. http://dx.doi.org/10.1016/j.psyneuen.2019.07.168 . 10.1016/j.psyneuen.2019.07.168 . published Psychoneuroendocrinology
Preparation of Mouse Retinal Cryo-sections for Immunohistochemistry.
Léger, Hélène, Journal of visualized experiments : JoVE. 2019. https://doi.org/10.3791/59683 . 10.3791/59683 . Journal of visualized experiments : JoVE
Ndr kinases regulate retinal interneuron proliferation and homeostasis
Hélène Léger; Evelyn Santana; N. Adrian Leu; Eliot T. Smith; William A. Beltran; Gustavo D. Aguirre; Francis C. Luca, Scientific Reports. 1. 8. 2018. https://doi.org/10.1038/s41598-018-30492-9 . 10.1038/s41598-018-30492-9 . Scientific Reports
Alternative Splicing of TAF6: Downstream Transcriptome Impacts and Upstream RNA Splice Control Elements
Kamtchueng, Catherine; Stébenne, Marie-Éve; Delannoy, Aurélie; Wilhelm, Emmanuelle; Léger, Hélène; Benecke, Arndt G.; Bell, Brendan, PLoS ONE. 7. 9. 2014. http://dx.doi.org/10.1371/journal.pone.0102399 . 10.1371/journal.pone.0102399 . PLoS ONE
A TDG/CBP/RARa Ternary Complex Mediates the Retinoic Acid-dependent Expression of DNA Methylation-sensitive Genes
Léger, Hélène; Smet-Nocca, Caroline; Attmane-Elakeb, Amel; Morley-Fletcher, Sara; Benecke, Arndt G.; Eilebrecht, Sebastian, Genomics, Proteomics & Bioinformatics. 8 - 18. 1. 12. 2014. http://dx.doi.org/10.1016/j.gpb.2013.11.001 . 10.1016/j.gpb.2013.11.001 . Genomics, Proteomics & Bioinformatics
Toll-like receptor 4 orchestrates neutrophil recruitment into airways during the first hours of Bordetella pertussis infection
Moreno, Griselda; Errea, Agustina; Van Maele, Laurye; Roberts, Roy; Léger, Hélène; Sirard, Jean Claude; Benecke, Arndt; Rumbo, Martin; Hozbor, Daniela, Microbes and Infection. 708 - 718. 10-11. 15. 2013. http://dx.doi.org/10.1016/j.micinf.2013.06.010 . 10.1016/j.micinf.2013.06.010 . Microbes and Infection
Protection against Streptococcus pneumoniae serotype 1 acute infection shows a signature of Th17- and IFN-¿-mediated immunity
Marqués, Juan M.; Rial, Analía; Muñoz, Natalia; Pellay, Francois-Xavier; Van Maele, Laurye; Léger, Hélène; Camou, Teresa; et al, Immunobiology. 420 - 429. 4. 217. 2012. http://dx.doi.org/10.1016/j.imbio.2011.10.012 . 10.1016/j.imbio.2011.10.012 . Immunobiology
Key Role for Respiratory CD103+ Dendritic Cells, IFN- , and IL-17 in Protection Against Streptococcus pneumoniae Infection in Response to -Galactosylceramide
Ivanov, S.; Fontaine, J.; Paget, C.; Macho Fernandez, E.; Van Maele, L.; Renneson, J.; Maillet, I.; et al, Journal of Infectious Diseases. 723 - 734. 5. 206. 2012. http://dx.doi.org/10.1093/infdis/jis413 . 10.1093/infdis/jis413 . Journal of Infectious Diseases
HMGA1-dependent and independent 7SK RNA gene regulatory activity
Eilebrecht, S.; Bécavin, C.; Léger, H.; Benecke, B.-J.; Benecke, A.; Eilebrecht, Sebastian; Bécavin, Christophe; et al, RNA Biology. 143 - 157. 1. 8. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952213061&partnerID=MN8TOARS . 10.4161/rna.V.I.14261 . RNA Biology
SUMO-1 regulates the conformational dynamics of Thymine-DNA Glycosylase regulatory domain and competes with its DNA binding activity
Smet-Nocca, Caroline; Wieruszeski, Jean-Michel; Léger, Hélène; Eilebrecht, Sebastian; Benecke, Arndt, BMC Biochemistry. 1. 12. 2011. http://dx.doi.org/10.1186/1471-2091-12-4 . 10.1186/1471-2091-12-4 . BMC Biochemistry
Characterization of the transcriptional networks involving PEA3 transcription factors during mammary morphogenesis and tumourigenesis
Ladam, F.; Leger, H.; Kherrouche, Z.; Tulasne, D.; Benecke, A.; de Launoit, Y.; Chotteau-Lelièvre, A., European Journal of Cancer Supplements. 5. 8. 2010. http://dx.doi.org/10.1016/s1359-6349(10)71158-7 . 10.1016/s1359-6349(10)71158-7 . European Journal of Cancer Supplements
TLR5 Signaling Stimulates the Innate Production of IL-17 and IL-22 by CD3negCD127+ Immune Cells in Spleen and Mucosa
Van Maele, L.; Carnoy, C.; Cayet, D.; Songhet, P.; Dumoutier, L.; Ferrero, I.; Janot, L.; et al, The Journal of Immunology. 1177 - 1185. 2. 185. 2010. http://dx.doi.org/10.4049/jimmunol.1000115 . 10.4049/jimmunol.1000115 . The Journal of Immunology
5 13 out of 13 Publications
All projects
Information of exclusive responsibility of the researcher 14-05-2024 , from platform CIÊNCIAVITAE.
2023/01 - 2024/06
Ndr2 kinase: a novel player in the regulation of microglia in Diabetic Retinopathy
2022.06170.PTDC
Principal investigator
Funders: Fundação para a Ciência e Tecnologia
2020/01
The effect of DPP-4 inhibitor sitagliptin on inflammation mediated by microglial cells
unknown
Researcher
2020/01/01
Investigate the mechanisms of NDR kinases in inflammation-induced angiogenesis in mouse retinas
IT057-19-8135
Principal investigator
Coimbra Institute for Clinical and Biomedical Research
2016 - 2019
Investigate the molecular mechanisms of NDR kinases and their substrates on cell division and cell fate in the retina
unknown
Post-doc
University of Pennsylvania
Funders: University of Pennsylvania
2016 - 2019
Investigate the molecular mechanisms of NDR kinases and their substrates on cell division and cell fate in the retina
unknown
Post-doc
University of Pennsylvania
Funders: University of Pennsylvania
2015 - 2016
A Zebrafish model for investigating Ndr kinase-dependent retina development
Unknown
Post-doc
University of Pennsylvania School of Veterinary Medicine
2015 - 2016
A Zebrafish model for investigating Ndr kinase-dependent retina development
Unknown
Post-doc
University of Pennsylvania School of Veterinary Medicine
2014 - 2019
Examining the role of Cbk1/NDR kinase in regulating mRNA localization
5R01GM097327-03
Post-doc
Funders: National Institute of General Medical Sciences
2014 - 2019
Examining the role of Cbk1/NDR kinase in regulating mRNA localization
5R01GM097327-03
Post-doc
Funders: National Institute of General Medical Sciences
2012 - 2014
Functional studies of TDG and its partners in epigenetic regulation of transcription
Unknown
Post-doc
5 10 out of 10 projects
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