Ildete Luisa Araujo Ferreira

Modified Glutamatergic Postsynapse in Neurodegenerative Disorders

Moraes, BJ; Coelho, P; Fão, L; Ferreira, IL; Rego, AC, Neuroscience. 2021. http://dx.doi.org/10.1016/j.neuroscience.2019.12.002 . 10.1016/j.neuroscience.2019.12.002 . published Neuroscience

Boldine Attenuates Synaptic Failure and Mitochondrial Deregulation in Cellular Models of Alzheimer's Disease

Toledo, JP; Fernández-Pérez, EJ; Ferreira, IL; Marinho, D; Riffo-Lepe, NO; Pineda-Cuevas, BN; Pinochet-Pino, LF; et al, Frontiers in Neuroscience. 15. 2021. http://dx.doi.org/10.3389/fnins.2021.617821 . 10.3389/fnins.2021.617821 . Frontiers in Neuroscience

Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer's disease mouse model

Ferreiro, E; Lanzillo, M; Canhoto, D; Carvalho da Silva, AM; Mota, SI; Dias, IS; Ferreira, IL; et al, Neurobiology of Aging. 98 - 113. 92. 2020. http://dx.doi.org/10.1016/j.neurobiolaging.2020.04.003 . 10.1016/j.neurobiolaging.2020.04.003 . published Neurobiology of Aging

Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer's disease features in cortical neurons

Silva, DF; Candeias, E; Esteves, AR; Magalhães, JD; Ferreira, IL; Nunes-Costa, D; Rego, AC; Empadinhas, N; Cardoso, SM, Journal of Neuroinflammation. 1. 17. 2020. http://dx.doi.org/10.1186/s12974-020-02004-y . 10.1186/s12974-020-02004-y . published Journal of Neuroinflammation

Characterization of subventricular zone-derived progenitor cells from mild and late symptomatic YAC128 mouse model of Huntington's disease

Silva, AC; Ferreira, IL; Hayden, MR; Ferreiro, E; Rego, AC, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 34 - 44. 1. 1864. 2018. http://dx.doi.org/10.1016/j.bbadis.2017.09.009 . 10.1016/j.bbadis.2017.09.009 . published Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Mitochondrial Ca2+ handling in Huntington's and Alzheimer's diseases – Role of ER-mitochondria crosstalk

Naia, L; Ferreira, IL; Ferreiro, E; Rego, AC, Biochemical and Biophysical Research Communications. 1069 - 1077. 4. 483. 2017. http://dx.doi.org/10.1016/j.bbrc.2016.07.122 . 10.1016/j.bbrc.2016.07.122 . Biochemical and Biophysical Research Communications

Aß and NMDAR activation cause mitochondrial dysfunction involving ER calcium release

Ferreira, IL; Ferreiro, E; Schmidt, J; Cardoso, JM; Pereira, CM; Carvalho, AL; Oliveira, CR; Rego, AC, Neurobiology of Aging. 680 - 692. 2. 36. 2015. http://dx.doi.org/10.1016/j.neurobiolaging.2014.09.006 . 10.1016/j.neurobiolaging.2014.09.006 . published Neurobiology of Aging

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

Mota, SI; Costa, RO; Ferreira, IL; Santana, I; Caldeira, GL; Padovano, C; Fonseca, AC; et al, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1428 - 1441. 7. 1852. 2015. http://dx.doi.org/10.1016/j.bbadis.2015.03.015 . 10.1016/j.bbadis.2015.03.015 . published Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Dysfunctional synapse in Alzheimer's disease: A focus on NMDA receptors

Mota, SI; Ferreira, IL; Rego, AC, Neuropharmacology. 16 - 26. 76. 2014. http://dx.doi.org/10.1016/j.neuropharm.2013.08.013 . 10.1016/j.neuropharm.2013.08.013 . published Neuropharmacology

OXPHOS dysfunction regulates integrin- 1 modifications and enhances cell motility and migration

Nunes, JB; Peixoto, J; Soares, P; Maximo, V; Carvalho, S.; Pinho, SS; Vieira, AF; et al, Human Molecular Genetics. 1977 - 1990. 7. 24. 2014. http://dx.doi.org/10.1093/hmg/ddu612 . 10.1093/hmg/ddu612 . published Human Molecular Genetics

Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human Lymphoblasts

Naia, L; Ferreira, IL; Cunha-Oliveira, T; Duarte, AI; Ribeiro, M; Rosenstock, TR; Laço, MN; et al, Molecular Neurobiology. 331 - 348. 1. 51. 2014. http://dx.doi.org/10.1007/s12035-014-8735-4 . 10.1007/s12035-014-8735-4 . published Molecular Neurobiology

Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus — Linking NMDA receptors and the reelin pathway

Mota, SI; Ferreira, IL; Valero, J; Ferreiro, E; Carvalho, AL; Oliveira, CR; Rego, AC, Experimental Neurology. 698 - 709. 261. 2014. http://dx.doi.org/10.1016/j.expneurol.2014.07.023 . 10.1016/j.expneurol.2014.07.023 . published Experimental Neurology

Impaired transcription in Alzheimer's disease: key role in mitochondrial dysfunction and oxidative stress

Caldeira, GL; Ferreira, IL; Rego, AC, Journal of Alzheimer's Disease. 115 - 131. 1. 34. 2013. https://doi.org/10.3233/jad-121444 . 10.3233/JAD-121444 . published Journal of Alzheimer's Disease

Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells

Ribeiro, M; Rosenstock, TR; Cunha-Oliveira, T; Ferreira, IL; Oliveira, CR; Rego, AC, Free Radical Biology and Medicine. 1857 - 1867. 10. 53. 2012. http://dx.doi.org/10.1016/j.freeradbiomed.2012.09.004 . 10.1016/j.freeradbiomed.2012.09.004 . published Free Radical Biology and Medicine

Endoplasmic reticulum stress occurs downstream of GluN2B subunit ofN-methyl-D-aspartate receptor in mature hippocampal cultures treated with amyloid-ß oligomers

Costa, RO; Lacor, PN; Ferreira, IL; Resende, R; Auberson, YP; Klein, WL; Oliveira, CR; Rego, AC; Pereira, CM, Aging Cell. 823 - 833. 5. 11. 2012. http://dx.doi.org/10.1111/j.1474-9726.2012.00848.x . 10.1111/j.1474-9726.2012.00848.x . published Aging Cell

Amyloid-Beta Peptide 1-42 Causes Microtubule Deregulation through N-methyl-D-aspartate Receptors in Mature Hippocampal Cultures

Mota, SI; Ferreira, IL; Pereira, CM; Oliveira, CR; Rego, AC, Current Alzheimer Research. 844 - 856. 7. 9. 2012. http://dx.doi.org/10.2174/156720512802455322 . 10.2174/156720512802455322 . published Current Alzheimer Research

Mitochondrial- and Endoplasmic Reticulum-Associated Oxidative Stress in Alzheimer's Disease: From Pathogenesis to Biomarkers

Ferreiro, E; Baldeiras, I; Ferreira, IL; Costa, RO; Rego, AC; Pereira, CM; Oliveira, CR, International Journal of Cell Biology. 1 - 23. 2012. 2012. http://dx.doi.org/10.1155/2012/735206 . 10.1155/2012/735206 . published International Journal of Cell Biology

Amyloid beta peptide 1–42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures

Ferreira, IL; Bajouco, LM; Mota, SI; Auberson, YP; Oliveira, CR; Rego, AC, Cell Calcium. 95 - 106. 2. 51. 2012. http://dx.doi.org/10.1016/j.ceca.2011.11.008 . 10.1016/j.ceca.2011.11.008 . published Cell Calcium

FK506 ameliorates cell death features in Huntington’s disease striatal cell models

Rosenstock, TR; de Brito, OM; Lombardi, V; Louros, S; Ribeiro, M; Almeida, S; Ferreira, IL; Oliveira, CR; Rego, AC, Neurochemistry International. 600 - 609. 5. 59. 2011. http://dx.doi.org/10.1016/j.neuint.2011.04.009 . 10.1016/j.neuint.2011.04.009 . published Neurochemistry International

Bioenergetic dysfunction in Huntington's disease human cybrids

Ferreira, IL; Cunha-Oliveira, T; Nascimento, MV; Ribeiro, M; Proença, MT; Januário, C; Oliveira, CR; Rego, AC, Experimental Neurology. 127 - 134. 1. 231. 2011. https://doi.org/10.1016/j.expneurol.2011.05.024 . 10.1016/j.expneurol.2011.05.024 . published Experimental Neurology

Northeast Portuguese propolis protects against staurosporine and hydrogen peroxide-induced neurotoxicity in primary cortical neurons

Cardoso, SM; Ribeiro, M; Ferreira, IL; Rego, AC, Food and Chemical Toxicology. 2862 - 2868. 11. 49. 2011. http://dx.doi.org/10.1016/j.fct.2011.08.010 . 10.1016/j.fct.2011.08.010 . published Food and Chemical Toxicology

Multiple Defects in Energy Metabolism in Alzheimers Disease

Ferreira, IL; Resende, R; Ferreiro, E; Rego, AC; Pereira, CM, Current Drug Targets. 1193 - 1206. 10. 11. 2010. http://dx.doi.org/10.2174/1389450111007011193 . 10.2174/1389450111007011193 . published Current Drug Targets

Mitochondrial-dependent apoptosis in Huntington's disease human cybrids

Ferreira, IL; Nascimento, MV; Ribeiro, M; Almeida, S; Cardoso, SM; Grazina, M; Pratas, J; et al, Experimental Neurology. 243 - 255. 2. 222. 2010. http://dx.doi.org/10.1016/j.expneurol.2010.01.002 . 10.1016/j.expneurol.2010.01.002 . published Experimental Neurology

Mitochondrial function in Parkinson’s disease cybrids containing an nt2 neuron-like nuclear background

Esteves, AR; Domingues, AF; Ferreira, IL; Januário, C; Swerdlow, RH; Oliveira, CR; Cardoso, SM, Mitochondrion. 219 - 228. 3. 8. 2008. http://dx.doi.org/10.1016/j.mito.2008.03.004 . 10.1016/j.mito.2008.03.004 . published Mitochondrion

Glutamate in Life and Death of Retinal Amacrine Cells

Duarte, CB; Ferreira, IL; Santos, PF; Carvalho, AL; Agostinho, PM; Carvalho, AP, General Pharmacology: The Vascular System. 289 - 295. 3. 30. 1998. http://dx.doi.org/10.1016/s0306-3623(97)00360-1 . 10.1016/s0306-3623(97)00360-1 . published General Pharmacology: The Vascular System

Kainate-induced retina amacrine-like cell damage is mediated by AMPA receptors

Ferreira, IL; Duarte, CB; Carvalho, AP, NeuroReport. 3471 - 3475. 15. 9. 1998. http://dx.doi.org/10.1097/00001756-199810260-00025 . 10.1097/00001756-199810260-00025 . published NeuroReport

Culture medium components modulate retina cell damage induced by glutamate, kainate or “chemical ischemia”

Ferreira, IL; Duarte, CB; Neves, AR; Carvalho, AP, Neurochemistry International. 387 - 396. 4. 32. 1998. http://dx.doi.org/10.1016/s0197-0186(97)00099-5 . 10.1016/s0197-0186(97)00099-5 . published Neurochemistry International

'Chemical ischemia' in cultured retina cells: The role of excitatory amino acid receptors and of energy levels on cell death

Ferreira, IL; Duarte, CB; Carvalho, AP, Brain Research. 157 - 166. 1-2. 768. 1997. https://doi.org/10.1016/s0006-8993(97)00634-3 . 10.1016/S0006-8993(97)00634-3 . published Brain Research

Ca2+ influx through glutamate receptor-associated channels in retina cells correlates with neuronal cell death

Ferreira, IL; Duarte, CB; Carvalho, AP, European Journal of Pharmacology. 153 - 162. 1-3. 302. 1996. http://dx.doi.org/10.1016/0014-2999(96)00044-1 . 10.1016/0014-2999(96)00044-1 . published European Journal of Pharmacology

Relation of [Ca2+]i to dopamine release in striatal synaptosomes: role of Ca2+ channels

Carvalho, CM; Ferreira, IL; Duarte, CB; Malva, JO; Tretter, L; Adam-Vizi, V; Carvalho, AP, Brain Research. 234 - 244. 2. 669. 1995. https://doi.org/10.1016/0006-8993(94)01252-d . 10.1016/0006-8993(94)01252-d . Brain Research

Glutamate Receptor Modulation of [3H]GABA Release and Intracellular Calcium in Chick Retina Cellsa

Carvalho, AP; Ferreira, IL; Carvalho, AL; Duarte, CB, Annals of the New York Academy of Sciences. 439 - 456. 1. 757. 1995. http://dx.doi.org/10.1111/j.1749-6632.1995.tb17504.x . 10.1111/j.1749-6632.1995.tb17504.x . published Annals of the New York Academy of Sciences

Domoic acid induced release of [3H]GABA in cultured chick retina cells

Alfonso, M; Duran, R; Duarte, CB; Ferreira, IL; Carvalho, AP, Neurochemistry International. 267 - 274. 3. 24. 1994. https://doi.org/10.1016/0197-0186(94)90084-1 . 10.1016/0197-0186(94)90084-1 . published Neurochemistry International

Release of [3H]GABA evoked by glutamate receptor agonists in cultured chick retina cells: effect of Ca2+

Ferreira, I.L.; Duarte, C.B.; Santos, P.F.; Carvalho, C.M.; Carvalho, A.P., Brain Research. 252 - 256. 1-2. 664. 1994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028172872&partnerID=MN8TOARS . 10.1016/0006-8993(94)91981-x . Brain Research

Relation of exocytotic release of ¿-aminobutyric acid to Ca2+ entry through Ca2+ channels or by reversal of the Na+/Ca2+ exchanger in synaptosomes

Duarte, CB; Ferreira, IL; Carvalho, AP; Carvalho, CM, Pflügers Archiv European Journal of Physiology. 314 - 323. 3-4. 423. 1993. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027263283&partnerID=MN8TOARS . 10.1007/BF00374411 . published Pflügers Archiv European Journal of Physiology

Glutamate increases the [Ca2+]i but stimulates Ca2+-independent release of [3H]GABA in cultured chick retina cells

Duarte, C.B.; Ferreira, I.L.; Santos, P.F.; Oliveira, C.R.; Carvalho, A.P., Brain Research. 130 - 138. 1. 611. 1993. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027335488&partnerID=MN8TOARS . Brain Research

Ca2+-dependent release of [3H]GABA in cultured chick retina cells

Duarte, CB; Ferreira, IL; Santos, PF; Oliveira, CR; Carvalho, AP, Brain Research. 27 - 32. 1. 591. 1992. http://dx.doi.org/10.1016/0006-8993(92)90974-e . 10.1016/0006-8993(92)90974-e . published Brain Research

Synaptosomal [Ca2+]i as influenced by Na+ Ca2+ exchange and K+ depolarization

Duarte, CB; Carvalho, CM; Ferreira, IL; Carvalho, AP, Cell Calcium. 623 - 633. 9. 12. 1991. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025917963&partnerID=MN8TOARS . 10.1016/0143-4160(91)90059-n . published Cell Calcium

Regulation of carrier-mediated and exocytotic release of [3H]GABA in rat brain synaptosomes

Carvalho, CM; Duarte, CB; Ferreira, IL; Carvalho, AP, Neurochemical Research. 763 - 772. 7. 16. 1991. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025820698&partnerID=MN8TOARS . 10.1007/BF00965685 . published Neurochemical Research

Calcium stores in electropermeabilized HL-60 cells before and after differentiation

Regateiro, FJ; Carvalho, CM; Ferreira, IL; Bairos, VA; Carvalho, AP, Cellular Signalling. 41 - 49. 1. 3. 1991. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026064436&partnerID=MN8TOARS . 10.1016/0898-6568(91)90006-g . published Cellular Signalling

Sodium-calcium exchange in nerve terminals: Influence on internal Ca2+ and neurosecretion

Carvalho, AP; Bandeira-Duarte, C.; Ferreira, I.L.; Coutinho, O.P.; Carvalho, CM, Annals of the New York Academy of Sciences. 300 - 311. 639. 1991. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026377475&partnerID=MN8TOARS . Annals of the New York Academy of Sciences