João Paulo Soeiro Terra Teodoro

The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function

João S. Teodoro; João A. Amorim; Ivo F. Machado; Ana C. Castela; Clemens Steegborn; David A. Sinclair; Anabela P. Rolo; Carlos M. Palmeira, International Journal of Molecular Sciences. 4896 - 4896. 14. 21. 2020. https://doi.org/10.3390/ijms21144896 . 10.3390/ijms21144896 . International Journal of Molecular Sciences

Exploration of the cellular effects of the high-dose, long-term exposure to coffee roasting product furan and its by-product cis-2-butene-1,4-dial on human and rat hepatocytes

João S. Teodoro; Rui Silva; António Aguiar; Abílio J. F. N. Sobral; Anabela P. Rolo; Carlos M. Palmeira, Toxicology Mechanisms and Methods. 1 - 10. 2020. https://doi.org/10.1080/15376516.2020.1780361 . 10.1080/15376516.2020.1780361 . Toxicology Mechanisms and Methods

Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats

Sara Nunes; Sofia D. Viana; Inês Preguiça; André Alves; Rosa Fernandes; João S. Teodoro; Artur Figueirinha; et al, Pharmaceutics. 2020. https://doi.org/10.3390/pharmaceutics12111094 . 10.3390/pharmaceutics12111094 . Pharmaceutics

Mitohormesis and metabolic health: The interplay between ROS, cAMP and sirtuins

Palmeira, C.M.; Teodoro, J.S.; Amorim, J.A.; Steegborn, C.; Sinclair, D.A.; Rolo, A.P., Free Radical Biology and Medicine. 483 - 491. 141. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85069629808&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2019.07.017 . Free Radical Biology and Medicine

Therapeutic options targeting oxidative stress, mitochondrial dysfunction and inflammation to hinder the progression of vascular complications of diabetes

Teodoro, J.S.; Nunes, S.; Rolo, A.P.; Reis, F.; Palmeira, C.M., Frontiers in Physiology. JAN. 10. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065463466&partnerID=MN8TOARS . 10.3389/fphys.2018.01857 . Frontiers in Physiology

miR-378a: a new emerging microRNA in metabolism

Machado, I.F.; Teodoro, J.S.; Palmeira, C.M.; Rolo, A.P., Cellular and Molecular Life Sciences. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075434955&partnerID=MN8TOARS . 10.1007/s00018-019-03375-z . Cellular and Molecular Life Sciences

Evaluation of bioenergetic and mitochondrial function in liver transplantation

Martins, R.M.; Teodoro, J.S.; Furtado, E.; Rolo, A.P.; Palmeira, C.M.; Tralhão, J.G., Clinical and Molecular Hepatology. 190 - 198. 2. 25. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068517981&partnerID=MN8TOARS . 10.3350/cmh.2018.0087 . Clinical and Molecular Hepatology

Mild hypothermia during the reperfusion phase protects mitochondrial bioenergetics against ischemia-reperfusion injury in an animal model of ex-vivo liver transplantation—An experimental study

Martins, R.M.; Teodoro, J.S.; Furtado, E.; Oliveira, R.C.; Tralhão, J.G.; Rolo, A.P.; Palmeira, C.M., International Journal of Medical Sciences. 1304 - 1312. 9. 16. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072941379&partnerID=MN8TOARS . 10.7150/ijms.34617 . International Journal of Medical Sciences

Indirubin and NAD+ prevent mitochondrial ischaemia/reperfusion damage in fatty livers

João Soeiro Teodoro; Ana Teresa Varela; Filipe Valente Duarte; Ana Patrícia Gomes; Carlos Marques Palmeira; Anabela Pinto Rolo, European Journal of Clinical Investigation. e12932 - e12932. 2018. https://doi.org/10.1111/eci.12932 . 10.1111/eci.12932 . European Journal of Clinical Investigation

Addition of berberine to preservation solution in an animal model of ex vivo liver transplant preserves mitochondrial function and bioenergetics from the damage induced by ischemia/reperfusion

Martins, R.M.; Rolo, A.P.; Teodoro, J.S.; Furtado, E.; Oliveira, R.C.; Tralhão, J.G.; Palmeira, C.M., International Journal of Molecular Sciences. 1. 19. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040938454&partnerID=MN8TOARS . 10.3390/ijms19010284 . International Journal of Molecular Sciences

Recent insights into mitochondrial targeting strategies in liver transplantation

Martins, R.M.; Teodoro, J.S.; Furtado, E.; Rolo, A.P.; Palmeira, C.M.; Tralhão, J.G., International Journal of Medical Sciences. 248 - 256. 3. 15. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045188539&partnerID=MN8TOARS . 10.7150/ijms.22891 . International Journal of Medical Sciences

Unacylated ghrelin prevents mitochondrial dysfunction in a model of ischemia/reperfusion liver injury

Alberto Rossetti; Gabriele Togliatto; Anabela P Rolo; João S Teodoro; Riccarda Granata; Ezio Ghigo; Amedeo Columbano; Carlos M Palmeira; Maria Felice Brizzi, Cell Death Discovery. 1. 3. 2017. https://doi.org/10.1038/cddiscovery.2017.77 . 10.1038/cddiscovery.2017.77 . Cell Death Discovery

Bioenergetic adaptations of the human liver in the ALPPS procedure – how liver regeneration correlates with mitochondrial energy status

Alexandrino, H.; Rolo, A.; Teodoro, J.S.; Donato, H.; Martins, R.; Serôdio, M.; Martins, M.; et al, HPB. 1091 - 1103. 12. 19. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029605721&partnerID=MN8TOARS . 10.1016/j.hpb.2017.08.005 . HPB

Lack of additive effects of resveratrol and energy restriction in the treatment of hepatic steatosis in rats

Milton-Laskibar, I.; Aguirre, L.; Fernández-Quintela, A.; Rolo, A.P.; Teodoro, J.S.; Palmeira, C.M.; Portillo, M.P., Nutrients. 7. 9. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85023760594&partnerID=MN8TOARS . 10.3390/nu9070737 . Nutrients

Adenosine receptors: regulatory players in the preservation of mitochondrial function induced by ischemic preconditioning of rat liver

Duarte, F.V.; Amorim, J.A.; Varela, A.T.; Teodoro, J.S.; Gomes, A.P.; Cunha, R.A.; Palmeira, C.M.; Rolo, A.P., Purinergic Signalling. 179 - 190. 2. 13. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84995486129&partnerID=MN8TOARS . 10.1007/s11302-016-9548-x . Purinergic Signalling

The bile acid chenodeoxycholic acid directly modulates metabolic pathways in white adipose tissue in vitro: insight into how bile acids decrease obesity

Teodoro, J.S.; Rolo, A.P.; Jarak, I.; Palmeira, C.M.; Carvalho, R.A., NMR in Biomedicine. 1391 - 1402. 10. 29. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988530079&partnerID=MN8TOARS . 10.1002/nbm.3583 . NMR in Biomedicine

Hepatic and skeletal muscle mitochondrial toxicity of chitosan oligosaccharides of normal and diabetic rats

Teodoro, J.S.; Gomes, A.P.; Varela, A.T.; Duarte, F.V.; Rolo, A.P.; Palmeira, C.M., Toxicology Mechanisms and Methods. 650 - 657. 9. 26. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84992521755&partnerID=MN8TOARS . 10.1080/15376516.2016.1222643 . Toxicology Mechanisms and Methods

Low-dose, subchronic exposure to silver nanoparticles causes mitochondrial alterations in Sprague-Dawley rats

Teodoro, J.S.; Silva, R.; Varela, A.T.; Duarte, F.V.; Rolo, A.P.; Hussain, S.; Palmeira, C.M., Nanomedicine. 1359 - 1375. 11. 11. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84971483351&partnerID=MN8TOARS . 10.2217/nnm-2016-0049 . Nanomedicine

Mitochondrial bioenergetics and posthepatectomy liver dysfunction

Alexandrino, H.; Varela, A.T.; Teodoro, J.S.; Martins, M.A.; Rolo, A.P.; Tralhão, J.G.; Palmeira, C.M.; Castro e Sousa, F., European Journal of Clinical Investigation. 627 - 635. 7. 46. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84976546519&partnerID=MN8TOARS . 10.1111/eci.12639 . European Journal of Clinical Investigation

High-fat and obesogenic diets: Current and future strategies to fight obesity and diabetes

Teodoro, J.S.; Varela, A.T.; Rolo, A.P.; Palmeira, C.M., Genes and Nutrition. 4. 9. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904443541&partnerID=MN8TOARS . 10.1007/s12263-014-0406-6 . Genes and Nutrition

Enhancement of brown fat thermogenesis using chenodeoxycholic acid in mice

Teodoro, J.S.; Zouhar, P.; Flachs, P.; Bardova, K.; Janovska, P.; Gomes, A.P.; Duarte, F.V.; et al, International Journal of Obesity. 1027 - 1034. 8. 38. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905663740&partnerID=MN8TOARS . 10.1038/ijo.2013.230 . International Journal of Obesity

Declining NAD⁺ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging

Gomes, A.P.; Price, N.L.; Ling, A.J.Y.; Moslehi, J.J.; Montgomery, M.K.; Rajman, L.; White, J.P.; et al, Cell. 1624 - 1638. 7. 155. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893442805&partnerID=MN8TOARS . 10.1016/j.cell.2013.11.037 . Cell

The NAD ratio redox paradox: Why does too much reductive power cause oxidative stress?

Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M., Toxicology Mechanisms and Methods. 297 - 302. 5. 23. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878533789&partnerID=MN8TOARS . 10.3109/15376516.2012.759305 . Toxicology Mechanisms and Methods

Uncovering the beginning of diabetes: The cellular redox status and oxidative stress as starting players in hyperglycemic damage

Teodoro, J.S.; Gomes, A.P.; Varela, A.T.; Duarte, F.V.; Rolo, A.P.; Palmeira, C.M., Molecular and Cellular Biochemistry. 103 - 110. 1-2. 376. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874278002&partnerID=MN8TOARS . 10.1007/s11010-012-1555-9 . Molecular and Cellular Biochemistry

Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: A possible role for SirT3 activation

Teodoro, J.S.; Duarte, F.V.; Gomes, A.P.; Varela, A.T.; Peixoto, F.M.; Rolo, A.P.; Palmeira, C.M.; et al, Mitochondrion. 637 - 646. 6. 13. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884937949&partnerID=MN8TOARS . 10.1016/j.mito.2013.09.002 . Mitochondrion

Dibenzofuran-induced mitochondrial dysfunction: Interaction with ANT carrier

Duarte, F.V.; Gomes, A.P.; Teodoro, J.S.; Varela, A.T.; Moreno, A.J.M.; Rolo, A.P.; Palmeira, C.M., Toxicology in Vitro. 2160 - 2168. 8. 27. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885795993&partnerID=MN8TOARS . 10.1016/j.tiv.2013.08.009 . Toxicology in Vitro

Exposure to dibenzofuran triggers autophagy in lung cells

Duarte, F.V.; Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M., Toxicology Letters. 35 - 42. 1. 209. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84155176935&partnerID=MN8TOARS . 10.1016/j.toxlet.2011.11.029 . Toxicology Letters

Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis

Gomes, A.P.; Duarte, F.V.; Nunes, P.; Hubbard, B.P.; Teodoro, J.S.; Varela, A.T.; Jones, J.G.; et al, Biochimica et Biophysica Acta - Molecular Basis of Disease. 185 - 195. 2. 1822. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-83255163155&partnerID=MN8TOARS . 10.1016/j.bbadis.2011.10.008 . Biochimica et Biophysica Acta - Molecular Basis of Disease

SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function

Price, N.L.; Gomes, A.P.; Ling, A.J.Y.; Duarte, F.V.; Martin-Montalvo, A.; North, B.J.; Agarwal, B.; et al, Cell Metabolism. 675 - 690. 5. 15. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860477354&partnerID=MN8TOARS . 10.1016/j.cmet.2012.04.003 . Cell Metabolism

Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis

Rolo, A.P.; Teodoro, J.S.; Palmeira, C.M., Free Radical Biology and Medicine. 59 - 69. 1. 52. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84655169624&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2011.10.003 . Free Radical Biology and Medicine

Assessment of the toxicity of silver nanoparticles in vitro: A mitochondrial perspective

Teodoro, J.S.; Simões, A.M.; Duarte, F.V.; Rolo, A.P.; Murdoch, R.C.; Hussain, S.M.; Palmeira, C.M., Toxicology in Vitro. 664 - 670. 3. 25. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952039156&partnerID=MN8TOARS . 10.1016/j.tiv.2011.01.004 . Toxicology in Vitro

Exposure to dibenzofuran affects lung mitochondrial function in vitro

Duarte, F.V.; Simões, A.M.; Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M., Toxicology Mechanisms and Methods. 571 - 576. 8. 21. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053260979&partnerID=MN8TOARS . 10.3109/15376516.2011.576714 . Toxicology Mechanisms and Methods

Hepatic FXR: Key regulator of whole-body energy metabolism

Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M., Trends in Endocrinology and Metabolism. 458 - 466. 11. 22. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-82455164172&partnerID=MN8TOARS . 10.1016/j.tem.2011.07.002 . Trends in Endocrinology and Metabolism

Indirubin-3'-oxime prevents hepatic I/R damage by inhibiting GSK-3ß and mitochondrial permeability transition

Varela, A.T.; Simões, A.M.; Teodoro, J.S.; Duarte, F.V.; Gomes, A.P.; Palmeira, C.M.; Rolo, A.P., Mitochondrion. 456 - 463. 5. 10. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955424602&partnerID=MN8TOARS . 10.1016/j.mito.2010.04.006 . Mitochondrion

Exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and tetraethyl lead affects lung mitochondria bioenergetics

Simes, A.M.; Duarte, F.V.; Teodoro, J.S.; Rolo, A.P.; Palmeira, C.M., Toxicology Mechanisms and Methods. 1 - 6. 1. 20. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77149123078&partnerID=MN8TOARS . 10.3109/15376510903527916 . Toxicology Mechanisms and Methods

Prevention of I/R injury in fatty livers by ischemic preconditioning is associated with increased mitochondrial tolerance: The key role of ATPsynthase and mitochondrial permeability transition

Rolo, A.P.; Teodoro, J.S.; Peralta, C.; Rosello-Catafau, J.; Palmeira, C.M., Transplant International. 1081 - 1090. 11. 22. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349668693&partnerID=MN8TOARS . 10.1111/j.1432-2277.2009.00916.x . Transplant International

Differential alterations in mitochondrial function induced by a choline-deficient diet: Understanding fatty liver disease progression

Teodoro, J.S.; Rolo, A.P.; Duarte, F.V.; Simões, A.M.; Palmeira, C.M., Mitochondrion. 367 - 376. 5-6. 8. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-54949089576&partnerID=MN8TOARS . 10.1016/j.mito.2008.07.008 . Mitochondrion

Indirubin-3'-oxime impairs mitochondrial oxidative phosphorylation and prevents mitochondrial permeability transition induction

Varela, A.T.; Gomes, A.P.; Simões, A.M.; Teodoro, J.S.; Duarte, F.V.; Rolo, A.P.; Palmeira, C.M., Toxicology and Applied Pharmacology. 179 - 185. 2. 233. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-56049123388&partnerID=MN8TOARS . 10.1016/j.taap.2008.08.005 . Toxicology and Applied Pharmacology

Decreased ANT content in Zucker fatty rats: Relevance for altered hepatic mitochondrial bioenergetics in steatosis

Teodoro, J.; Rolo, A.P.; Oliveira, P.J.; Palmeira, C.M., FEBS Letters. 2153 - 2157. 8. 580. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645241135&partnerID=MN8TOARS . 10.1016/j.febslet.2006.02.078 . FEBS Letters