Maria João Freitas

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Researcher

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mjfreitas@uc.pt
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Overview

I hold a PhD in Biology and I have decade of experience in Molecular and Cellular Biology research. Throughout my career, I have developed excellent communication skills, by producing various scientific and medical communication activities, written successful scientific grant proposals, and earning recognition as a patented author. As a dedicated science communicator, I have experience in medical writing and effectively bridging the gap between scientific complexities and public understanding. In my role at MIA-Portugal, I am responsible for creating, organizing, and executing communication strategies that foster meaningful engagement between scientists and diverse audiences. I organize science dissemination events, including monthly scientific seminars, and actively contribute to initiatives such as the European Researcher's Night and International Brain Week. Furthermore, I successfully fundraised efforts to support science communication initiatives. At MIA-Portugal, I am in charge for managing all external communication endeavors, including media coverage and social media presence. Through these efforts, I am committed to promoting public awareness of the importance of scientific research.

Publications

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Information about journal articles, updated at 15-12-2024, from platform CIÊNCIAVITAE.

Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility

Silva, Joana Vieira; Freitas, Maria João; Santiago, Joana; Jones, Sarah; Guimarães, Sofia; Vijayaraghavan, Srinivasan; Publicover, Steven; et al, Fertility and Sterility. 348 - 362. 2. 115. 2021. http://dx.doi.org/10.1016/j.fertnstert.2020.08.013 . 10.1016/j.fertnstert.2020.08.013 . Fertility and Sterility

Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyrimidine-based protein kinase D inhibitors

Gilles, Philippe; Kashyap, Rudra S.; Freitas, Maria João; Ceusters, Sam; Van Asch, Koen; Janssens, Anke; De Jonghe, Steven; et al, European Journal of Medicinal Chemistry. 205. 2020. http://dx.doi.org/10.1016/j.ejmech.2020.112638 . 10.1016/j.ejmech.2020.112638 . European Journal of Medicinal Chemistry

Isoform-specific GSK3A activity is negatively correlated with human sperm motility

Freitas, M J; Silva, J V; Brothag, C; Regadas-Correia, B; Fardilha, M; Vijayaraghavan, S, MHR: Basic science of reproductive medicine. 171 - 183. 4. 25. 2019. http://dx.doi.org/10.1093/molehr/gaz009 . 10.1093/molehr/gaz009 . MHR: Basic science of reproductive medicine

Signaling proteins as biomarkers for sperm quality evaluation

Vieira Silva, J.; Freitas, M. J.; Correia, B.; Patricio, A.; Pelech, S.; Fardilha, M., Human Reproduction. 154 - 154. 32. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000416390501128&KeyUID=WOS:000416390501128 . Human Reproduction

Signaling mechanisms in mammalian sperm motility

Freitas, M.J.; Vijayaraghavan, S.; Fardilha, M., Biology of Reproduction. 2 - 12. 1. 96. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85022323534&partnerID=MN8TOARS . 10.1095/biolreprod.116.144337 . Biology of Reproduction

Study on the short-term effects of increased alcohol and cigarette consumption in healthy young men's seminal quality

Silva, J.V.; Cruz, D.; Gomes, M.; Correia, B.R.; Freitas, M.J.; Sousa, L.; Silva, V.; Fardilha, M., Scientific Reports. 7. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017028715&partnerID=MN8TOARS . 10.1038/srep45457 . Scientific Reports

Unravelling the Power of Omics for the Infertile Aging Male

Bastos, Paulo; Freitas, Maria Joao; Gomes, Andre; Vitorino, Rui; Fardilha, Margarida, Current Pharmaceutical Design. 4451 - 4469. 30. 23. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000416929300004&KeyUID=WOS:000416929300004 . 10.2174/1381612822666161018155247 . Current Pharmaceutical Design

Signaling fingerprint of the human spermatozoa: correlation with clinical data

Silva, Joana V.; Freitas, Maria Joao; Correia, Barbara R.; Korrodi-Gregorio, Luis; Patricio, Antonio; Pelech, Steven; Fardilha, Margarida, Medicine. 10. 95. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000375209300103&KeyUID=WOS:000375209300103 . Medicine

Protein Profile in Human Prostate Cancer

Freitas, Maria Joao; Silva, Joana V.; Felgueiras, Juliana; Patricio, Antonio; Maia, Nuno; Pelech, Steven; Fardilha, Margarida, Medicine. 10. 95. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000375209300178&KeyUID=WOS:000375209300178 . Medicine

Non-Stop Lab Week: A Real Laboratory Experience for Life Sciences Postgraduate Courses

Freitas, Maria Joao; Silva, Joana Vieira; Korrodi-Gregorio, Luis; Fardilha, Margarida, Biochemistry and Molecular Biology Education. 297 - 303. 3. 44. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000380265400010&KeyUID=WOS:000380265400010 . 10.1002/bmb.20947 . Biochemistry and Molecular Biology Education

Profiling signaling proteins in human spermatozoa: Biomarker identification for sperm quality evaluation

Silva, J.V.; Freitas, M.J.; Correia, B.R.; Korrodi-Gregório, L.; Patrício, A.; Pelech, S.; Fardilha, M., Fertility and Sterility. 845 - 856e8. 4. 104. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942817659&partnerID=MN8TOARS . 10.1016/j.fertnstert.2015.06.039 . Fertility and Sterility

Physical Activity, Exercise, and Mammalian Testis Function: Emerging Preclinical Protein Biomarker and Integrative Biology Insights

Gomes, M.; Freitas, M.J.; Fardilha, M., OMICS A Journal of Integrative Biology. 499 - 511. 9. 19. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941043263&partnerID=MN8TOARS . 10.1089/omi.2015.0065 . OMICS A Journal of Integrative Biology

The power of the yeast two-hybrid system in the identification of novel drug targets: Building and modulating PPP1 interactomes

Silva, J.V.; Freitas, M.J.; Felgueiras, J.; Fardilha, M., Expert Review of Proteomics. 147 - 158. 2. 12. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925301188&partnerID=MN8TOARS . 10.1586/14789450.2015.1024226 . Expert Review of Proteomics

Intraflagellar Protein 88 Interactome Analysis: A Bioinformatics Approach Highlights Its Role in Testis and Sperm Function

Freitas, Maria João; Fardilha, Margarida, Journal of Biophysical Chemistry. 99 - 106. 03. 05. 2014. http://dx.doi.org/10.4236/jbpc.2014.53011 . 10.4236/jbpc.2014.53011 . Journal of Biophysical Chemistry

Vias de sinalização reguladoras das funções do espermatozoide

Cruz, Daniel Filipe; Freitas, Maria João; Patrício, António; Fardilha, Margarida, Revista Internacional de Andrología. 104 - 111. 3. 12. 2014. http://dx.doi.org/10.1016/j.androl.2014.04.006 . 10.1016/j.androl.2014.04.006 . Revista Internacional de Andrología

Phosphoprotein phosphatase 1 complexes in spermatogenesis

Silva, J.V.; Freitas, M.J.; Fardilha, M., Current Molecular Pharmacology. 136 - 146. 2. 7. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930979437&partnerID=MN8TOARS . Current Molecular Pharmacology

TCTEX1D4 interactome in human testis: Unraveling the function of dynein light Chain in spermatozoa

Freitas, M.J.; Korrodi-Gregório, L.; Morais-Santos, F.; Da Cruz E Silva, E.; Fardilha, M., OMICS A Journal of Integrative Biology. 242 - 253. 4. 18. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897506850&partnerID=MN8TOARS . 10.1089/omi.2013.0133 . OMICS A Journal of Integrative Biology

TGF-ß cascade regulation by PPP1 and its interactors -impact on prostate cancer development and therapy

Korrodi-Gregório, L.; Silva, J.V.; Santos-Sousa, L.; Freitas, M.J.; Felgueiras, J.; Fardilha, M., Journal of Cellular and Molecular Medicine. 555 - 567. 4. 18. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897964073&partnerID=MN8TOARS . 10.1111/jcmm.12266 . Journal of Cellular and Molecular Medicine

TCTEX1D4, a novel protein phosphatase 1 interactor: Connecting the phosphatase to the microtubule network

Korrodi-Gregório, L.; Vieira, S.I.; Esteves, S.L.C.; Silva, J.V.; Freitas, M.J.; Brauns, A.-K.; Luers, G.; et al, Biology Open. 453 - 465. 5. 2. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84974652624&partnerID=MN8TOARS . 10.1242/bio.20131065 . Biology Open

Identification of therapeutic and diagnotic targets through yeast two hybrid system: Molecular biology in medicine | Identificação de alvos terapêuticos e de diagnóstico através do yeast two hybrid system: A biologia molecular na medicina

Freitas, M.J.; Korrodi-Gregório, L.; Esteves, S.; Fardilha, M., Acta Medica Portuguesa. 427 - 432. 6. 25. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873514438&partnerID=MN8TOARS . Acta Medica Portuguesa

TCTEX1D4 interactome: relevance for male reproductive function

Freitas, M. J.; Korrodi-Gregorio, L.; Esteves, S. L. C.; Fardilha, M., Febs Journal. 163 - 163. 279. 2012. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000308128601355&KeyUID=WOS:000308128601355 . Febs Journal

5 21 out of 21 Publications

All projects

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Information of exclusive responsibility of the researcher 15-12-2024 , from platform CIÊNCIAVITAE.

2021/10/01 - 2022/04/30

Deciphering the functional role of PKD2 driver mutations in Multiple Myeloma via an integrated multiomics approach.

00000

Post-doc Fellow

Katholieke Universiteit Leuven

2019/01/01 - 2019/12/31

Instituto de Biomedicina - Aveiro

UID/BIM/04501/2019

Universidade de Aveiro; Universidade de Aveiro Instituto de Biomedicina

Funders: Fundação para a Ciência e a Tecnologia

2018/10/01 - 2021/09/01

Selective tyrosine phosphorylation of the PKD2 activation segment: a novel regulatory mechanism to achieve isoenzyme specific signaling within the protein kinase D family.

G0C4118N

Post-doc Fellow

Katholieke Universiteit Leuven

Funders: Fonds Wetenschappelijk Onderzoek Vlaanderen

2016/07/01 - 2019/12/31

Interacções proteína-proteína como alvos terapêuticos: modulação de complexos da Fosfoproteina Fosfatase 1 na fertilidade masculina

PTDC/BBB-BQB/3804/2014

Universidade de Aveiro

Funders: Fundação para a Ciência e a Tecnologia

2016/07/01 - 2019/12/31

Interacções proteína-proteína como alvos terapêuticos: modulação de complexos da Fosfoproteina Fosfatase 1 na fertilidade masculina

PTDC/BBB-BQB/3804/2014

Universidade de Aveiro

Funders: Fundação para a Ciência e a Tecnologia

2013/12/01 - 2017/11/30

ADDRESSING SPERM MOTILITY REGULATION BY SPECIFIC PPP1 INHIBITORS

SFRH/BD/84876/2012

Universidade de Aveiro

Funders: Fundação para a Ciência e a Tecnologia

2013/07/01 - 2015/06/30

Plataforma para o diagnóstico e tratamento da infertilidade masculina baseada em vias de sinalização nos espermatozóides humanos

PTDC/DTP-PIC/0460/2012

Universidade de Aveiro

Funders: Fundação para a Ciência e a Tecnologia

5 7 out of 7 projects

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