Inês Morgado Martins

Extracellular vesicle-based delivery of silencing sequences for the treatment of Machado-Joseph disease/spinocerebellar ataxia type 3

Rufino-Ramos, David; Albuquerque, Patrícia R.; Leandro, Kevin; Carmona, Vitor; Martins, Inês M.; Fernandes, Rita; Henriques, Carina; et al, Molecular Therapy. 1275 - 1292. 5. 31. 2023. http://dx.doi.org/10.1016/j.ymthe.2023.04.001 . 10.1016/j.ymthe.2023.04.001 . Molecular Therapy

ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease

Vasconcelos-Ferreira, Ana; Martins, Inês Morgado; Lobo, Diana; Pereira, Dina; Lopes, Miguel M.; Faro, Rosário; Lopes, Sara M.; et al, Molecular Therapy. 370 - 387. 1. 30. 2022. http://dx.doi.org/10.1016/j.ymthe.2021.07.012 . 10.1016/j.ymthe.2021.07.012 . published Molecular Therapy

Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders

Silva, Ana C; Lobo, Diana D; Martins, Inês M; Lopes, Sara M; Henriques, Carina; Duarte, Sónia P; Dodart, Jean-Cosme; Nobre, Rui Jorge; Pereira de Almeida, Luis, Brain. 2019. http://dx.doi.org/10.1093/brain/awz328 . 10.1093/brain/awz328 . published Brain

Karyopherin a-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3

Sowa, Anna Sergeevna; Martin, Elodie; Martins, Inês Morgado; Schmidt, Jana; Depping, Reinhard; Weber, Jonasz Jeremiasz; Rother, Franziska; et al, Proceedings of the National Academy of Sciences. E2624 - E2633. 11. 115. 2018. http://dx.doi.org/10.1073/pnas.1716071115 . 10.1073/pnas.1716071115 . published Proceedings of the National Academy of Sciences

Divalproex sodium modulates nuclear localization of ataxin-3 and prevents cellular toxicity caused by expanded ataxin-3

Wang, Zi-Jian; Hanet, Aoife; Weishäupl, Daniel; Martins, Inês M.; Sowa, Anna S.; Riess, Olaf; Schmidt, Thorsten, CNS Neuroscience & Therapeutics. 404 - 411. 5. 24. 2018. http://dx.doi.org/10.1111/cns.12795 . 10.1111/cns.12795 . CNS Neuroscience & Therapeutics