Maria Isabel Santana

Prodromal language impairment in genetic frontotemporal dementia within the GENFI cohort

Samra, Kiran; MacDougall, Amy M.; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; et al, Journal of the Neurological Sciences. 451. 2023. http://dx.doi.org/10.1016/j.jns.2023.120711 . 10.1016/j.jns.2023.120711 . Journal of the Neurological Sciences

Textural properties of microglial activation in Alzheimer’s disease as measured by (R)-[11C]PK11195 PET

Lapo Pais, Marta; Jorge, Lília; Martins, Ricardo; Canário, Nádia; Xavier, Ana Carolina; Bernardes, Rui; Abrunhosa, Antero; Santana, Isabel; Castelo-Branco, Miguel, Brain Communications. 3. 5. 2023. http://dx.doi.org/10.1093/braincomms/fcad148 . 10.1093/braincomms/fcad148 . Brain Communications

Characterization of Progranulin Gene Mutations in Portuguese Patients with Frontotemporal Dementia

Almeida, Maria Rosário; Tábuas-Pereira, Miguel; Baldeiras, Inês; Lima, Marisa; Durães, João; Massano, João; Pinto, Madalena; Cruto, Catarina; Santana, Isabel, International Journal of Molecular Sciences. 1. 25. 2023. http://dx.doi.org/10.3390/ijms25010511 . 10.3390/ijms25010511 . International Journal of Molecular Sciences

Genetic forms of primary progressive aphasia within the GENetic Frontotemporal dementia Initiative (GENFI) cohort: comparison with sporadic primary progressive aphasia

Samra, Kiran; MacDougall, Amy M; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M; Greaves, Caroline V; Convery, Rhian S; et al, Brain Communications. 2. 5. 2023. http://dx.doi.org/10.1093/braincomms/fcad036 . 10.1093/braincomms/fcad036 . Brain Communications

Early neurotransmitters changes in prodromal frontotemporal dementia: A GENFI study

Premi, Enrico; Pengo, Marta; Mattioli, Irene; Cantoni, Valentina; Dukart, Juergen; Gasparotti, Roberto; Buratti, Emanuele; et al, Neurobiology of Disease. 179. 2023. http://dx.doi.org/10.1016/j.nbd.2023.106068 . 10.1016/j.nbd.2023.106068 . Neurobiology of Disease

Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementia

Bussy, Aurélie; Levy, Jake P.; Best, Tristin; Patel, Raihaan; Cupo, Lani; Van Langenhove, Tim; Nielsen, Jørgen E.; et al, Human Brain Mapping. 2684 - 2700. 7. 44. 2023. http://dx.doi.org/10.1002/hbm.26220 . 10.1002/hbm.26220 . Human Brain Mapping

Blood biomarkers in mild cognitive impairment patients: Relationship between analytes and progression to Alzheimer disease dementia

Silva-Spínola, Anuschka; Lima, Marisa; Leitão, Maria João; Bernardes, Catarina; Durães, João; Duro, Diana; Tábuas-Pereira, Miguel; Santana, Isabel; Baldeiras, Inês, European Journal of Neurology. 1565 - 1573. 6. 30. 2023. http://dx.doi.org/10.1111/ene.15762 . 10.1111/ene.15762 . European Journal of Neurology

Reconsidering the role of blood-brain barrier in Alzheimer’s disease: From delivery to target

Sousa, João André; Bernardes, Catarina; Bernardo-Castro, Sara; Lino, Miguel; Albino, Inês; Ferreira, Lino; Brás, José; et al, Frontiers in Aging Neuroscience. 15. 2023. http://dx.doi.org/10.3389/fnagi.2023.1102809 . 10.3389/fnagi.2023.1102809 . Frontiers in Aging Neuroscience

The Benson Complex Figure Test detects deficits in visuoconstruction and visual memory in symptomatic familial frontotemporal dementia: A GENFI study

Jiskoot, Lize C.; Russell, Lucy L.; Peakman, Georgia; Convery, Rhian S.; Greaves, Caroline V.; Bocchetta, Martina; Poos, Jackie M.; et al, Journal of the Neurological Sciences. 446. 2023. http://dx.doi.org/10.1016/j.jns.2023.120590 . 10.1016/j.jns.2023.120590 . Journal of the Neurological Sciences

Neuropsychiatric symptoms in genetic frontotemporal dementia: developing a new module for Clinical Rating Scales

Samra, Kiran; Macdougall, Amy; Peakman, Georgia; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M; Greaves, Caroline V; et al, Journal of Neurology, Neurosurgery & Psychiatry. 357 - 368. 5. 94. 2023. http://dx.doi.org/10.1136/jnnp-2022-330152 . 10.1136/jnnp-2022-330152 . Journal of Neurology, Neurosurgery & Psychiatry

Two Phase 3 Trials of Gantenerumab in Early Alzheimer’s Disease

Bateman, Randall J.; Smith, Janice; Donohue, Michael C.; Delmar, Paul; Abbas, Rachid; Salloway, Stephen; Wojtowicz, Jakub; et al, New England Journal of Medicine. 1862 - 1876. 20. 389. 2023. http://dx.doi.org/10.1056/nejmoa2304430 . 10.1056/nejmoa2304430 . New England Journal of Medicine

Neuropsychological Assessment in the Distinction Between Biomarker Defined Frontal-Variant of Alzheimer’s Disease and Behavioral-Variant of Frontotemporal Dementia

Lima, Marisa; Tábuas-Pereira, Miguel; Durães, João; Vieira, Daniela; Faustino, Pedro; Baldeiras, Inês; Santana, Isabel, Journal of Alzheimer's Disease. 1303 - 1312. 4. 91. 2023. http://dx.doi.org/10.3233/jad-220897 . 10.3233/jad-220897 . Journal of Alzheimer's Disease

Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease

Daniela Marinho; Ildete Luísa Ferreira; Ricardo Lorenzoni; Sandra M. Cardoso; Isabel Santana; A. Cristina Rego, Aging Cell. 2023. https://doi.org/10.1111/acel.13895 . 10.1111/acel.13895 . Aging Cell

Hemispheric Patterns of Recruitment of Object Processing Regions in Early Alzheimer’s Disease: A Study Along the Entire Ventral Stream

Canário, Nádia S.; Jorge, Lília P.; Santana, Isabel J.; Castelo-Branco, Miguel S., Journal of Alzheimer's Disease. 1151 - 1164. 3. 91. 2023. http://dx.doi.org/10.3233/jad-220055 . 10.3233/jad-220055 . Journal of Alzheimer's Disease

TREX1 p.A129fs and p.Y305C variants in a large multi-ethnic cohort of CADASIL-like unrelated patients

Foddis, Marco; Blumenau, Sonja; Holtgrewe, Manuel; Paquette, Kimberly; Westra, Kaitlyn; Alonso, Isabel; Macario, Maria do Carmo; et al, Neurobiology of Aging. 208 - 215. 123. 2023. http://dx.doi.org/10.1016/j.neurobiolaging.2022.11.013 . 10.1016/j.neurobiolaging.2022.11.013 . Neurobiology of Aging

Altered plasma protein profiles in genetic FTD – a GENFI study

Ullgren, Abbe; Öijerstedt, Linn; Olofsson, Jennie; Bergström, Sofia; Remnestål, Julia; van Swieten, John C.; Jiskoot, Lize C.; et al, Molecular Neurodegeneration. 1. 18. 2023. http://dx.doi.org/10.1186/s13024-023-00677-6 . 10.1186/s13024-023-00677-6 . Molecular Neurodegeneration

In vivo molecular imaging of the neuroinflammatory response to peripheral acute bacterial infection in older patients with cognitive dysfunction: A cross-sectional controlled study

Silva, Ana Rita; Regueira, Patricia; Peres, André; Cardoso, Ana Luísa; Baldeiras, Inês; Santana, Isabel; Cerejeira, Joaquim, Frontiers in Aging Neuroscience. 14. 2022. http://dx.doi.org/10.3389/fnagi.2022.984178 . 10.3389/fnagi.2022.984178 . published Frontiers in Aging Neuroscience

The Assessment of Cognitive Reserve: A Systematic Review of the Most Used Quantitative Measurement Methods of Cognitive Reserve for Aging

Nogueira, Joana; Gerardo, Bianca; Santana, Isabel; Simões, Mário R.; Freitas, Sandra, Frontiers in Psychology. 13. 2022. http://dx.doi.org/10.3389/fpsyg.2022.847186 . 10.3389/fpsyg.2022.847186 . published Frontiers in Psychology

Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study

van der Ende, Emma L.; Heller, Carolin; Sogorb-Esteve, Aitana; Swift, Imogen J.; McFall, David; Peakman, Georgia; Bouzigues, Arabella; et al, Journal of Neuroinflammation. 1. 19. 2022. http://dx.doi.org/10.1186/s12974-022-02573-0 . 10.1186/s12974-022-02573-0 . published Journal of Neuroinflammation

Exome Sequencing of a Portuguese Cohort of Frontotemporal Dementia Patients: Looking Into the ALS-FTD Continuum

Tábuas-Pereira, Miguel; Santana, Isabel; Gibbons, Elizabeth; Paquette, Kimberly; Almeida, Maria Rosário; Baldeiras, Inês; Bras, Jose; Guerreiro, Rita, Frontiers in Neurology. 13. 2022. http://dx.doi.org/10.3389/fneur.2022.886379 . 10.3389/fneur.2022.886379 . published Frontiers in Neurology

Motor symptoms in genetic frontotemporal dementia: developing a new module for clinical rating scales

Samra, Kiran; MacDougall, Amy M.; Peakman, Georgia; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; et al, Journal of Neurology. 2022. http://dx.doi.org/10.1007/s00415-022-11442-y . 10.1007/s00415-022-11442-y . published Journal of Neurology

Hierarchical spectral clustering reveals brain size and shape changes in asymptomatic carriers of <i>C9orf72</i>

Bruffaerts, Rose; Gors, Dorothy; Bárcenas Gallardo, Alicia; Vandenbulcke, Mathieu; Van Damme, Philip; Suetens, Paul; van Swieten, John C; et al, Brain Communications. 4. 4. 2022. http://dx.doi.org/10.1093/braincomms/fcac182 . 10.1093/braincomms/fcac182 . published Brain Communications

Dual PET-fMRI reveals a link between neuroinflammation, amyloid binding and compensatory task-related brain activity in Alzheimer’s disease

Canário, Nádia; Jorge, Lília; Martins, Ricardo; Santana, Isabel; Castelo-Branco, Miguel, Communications Biology. 1. 5. 2022. http://dx.doi.org/10.1038/s42003-022-03761-7 . 10.1038/s42003-022-03761-7 . published Communications Biology

CSF glial markers are elevated in a subset of patients with genetic frontotemporal dementia

Woollacott, Ione O. C.; Swift, Imogen J.; Sogorb-Esteve, Aitana; Heller, Carolin; Knowles, Kathryn; Bouzigues, Arabella; Russell, Lucy L.; et al, Annals of Clinical and Translational Neurology. 1764 - 1777. 11. 9. 2022. http://dx.doi.org/10.1002/acn3.51672 . 10.1002/acn3.51672 . published Annals of Clinical and Translational Neurology

Generation and Characterization of Novel iPSC Lines from a Portuguese Family Bearing Heterozygous and Homozygous GRN Mutations

Oliveira, Ana Rafaela; Martins, Solange; Cammarata, Giuseppe; Martins, Mariana; Cardoso, Ana Maria; Almeida, Maria Rosário; do Carmo Macário, Maria; et al, Biomedicines. 8. 10. 2022. http://dx.doi.org/10.3390/biomedicines10081905 . 10.3390/biomedicines10081905 . published Biomedicines

Clinical Application of Pharmacokinetics to Appraise Adherence to Levetiracetam in Portuguese Epileptic Patients

Silva, Rui; Bicker, Joana; Almeida, Anabela; Carona, Andreia; Silva, Ana; Sales, Francisco; Santana, Isabel; Falcão, Amílcar; Fortuna, Ana, Biomedicines. 9. 10. 2022. http://dx.doi.org/10.3390/biomedicines10092127 . 10.3390/biomedicines10092127 . published Biomedicines

Lewy body dementia is associated with an increased risk of atrial fibrillation: A case-control study

Tábuas-Pereira, Miguel; Durães, João; Beato-Coelho, José; Rita Nogueira, Ana; Duro, Diana; Baldeiras, Inês; Santana, Isabel, Journal of Clinical Neuroscience. 62 - 65. 99. 2022. http://dx.doi.org/10.1016/j.jocn.2022.02.038 . 10.1016/j.jocn.2022.02.038 . published Journal of Clinical Neuroscience

Frequency and Longitudinal Course of Motor Signs in Genetic Frontotemporal Dementia

Schönecker, Sonja; Martinez-Murcia, Francisco J.; Rauchmann, Boris-Stephan; Franzmeier, Nicolai; Prix, Catharina; Wlasich, Elisabeth; Loosli, Sandra V.; et al, Neurology. e1032 - e1044. 10. 99. 2022. http://dx.doi.org/10.1212/wnl.0000000000200828 . 10.1212/wnl.0000000000200828 . published Neurology

Examining empathy deficits across familial forms of frontotemporal dementia within the GENFI cohort

Foster, Phoebe H.; Russell, Lucy L.; Peakman, Georgia; Convery, Rhian S.; Bouzigues, Arabella; Greaves, Caroline V.; Bocchetta, Martina; et al, Cortex. 12 - 28. 150. 2022. http://dx.doi.org/10.1016/j.cortex.2022.01.012 . 10.1016/j.cortex.2022.01.012 . Cortex

Corrigendum to “Dissemination in time and space in presymptomatic granulin mutation carriers: A spatial chronnectome study” [Neurobiology of Aging Volume 108, December 2021, Pages 155–167]

Premi, Enrico; Giunta, Marcello; Iraji, Armin; Rachakonda, Srinivas; Calhoun, VinceD.; Gazzina, Stefano; Benussi, Alberto; et al, Neurobiology of Aging. 140 - 144. 119. 2022. http://dx.doi.org/10.1016/j.neurobiolaging.2022.08.005 . 10.1016/j.neurobiolaging.2022.08.005 . published Neurobiology of Aging

Whole-exome sequencing reveals PSEN1 and ATP7B combined variants as a possible cause of early-onset Lewy body dementia: a case study of genotype–phenotype correlation

Tábuas-Pereira, Miguel; Guerreiro, Rita; Kun-Rodrigues, Célia; Almeida, Maria Rosário; Brás, José; Santana, Isabel, neurogenetics. 279 - 283. 4. 23. 2022. http://dx.doi.org/10.1007/s10048-022-00699-0 . 10.1007/s10048-022-00699-0 . published neurogenetics

Alzheimer’s Disease Diagnosis Based on the Amyloid, Tau, and Neurodegeneration Scheme (ATN) in a Real-Life Multicenter Cohort of General Neurological Centers

Baldeiras, Inês; Silva-Spínola, Anuschka; Lima, Marisa; Leitão, Maria João; Durães, João; Vieira, Daniela; Tábuas-Pereira, Miguel; et al, Journal of Alzheimer's Disease. 419 - 432. 1. 90. 2022. http://dx.doi.org/10.3233/jad-220587 . 10.3233/jad-220587 . published Journal of Alzheimer's Disease

Loss of brainstem white matter predicts onset and motor neuron symptoms in C9orf72 expansion carriers: a GENFI study

Pérez-Millan, Agnès; Borrego-Écija, Sergi; van Swieten, John C.; Jiskoot, Lize; Moreno, Fermin; Laforce, Robert; Graff, Caroline; et al, Journal of Neurology. 2022. http://dx.doi.org/10.1007/s00415-022-11435-x . 10.1007/s00415-022-11435-x . published Journal of Neurology

Cognitive composites for genetic frontotemporal dementia: GENFI-Cog

Poos, Jackie M.; Moore, Katrina M.; Nicholas, Jennifer; Russell, Lucy L.; Peakman, Georgia; Convery, Rhian S.; Jiskoot, Lize C.; et al, Alzheimer's Research & Therapy. 1. 14. 2022. http://dx.doi.org/10.1186/s13195-022-00958-0 . 10.1186/s13195-022-00958-0 . published Alzheimer's Research & Therapy

An Automated Toolbox to Predict Single Subject Atrophy in Presymptomatic Granulin Mutation Carriers

Premi, Enrico; Costa, Tommaso; Gazzina, Stefano; Benussi, Alberto; Cauda, Franco; Gasparotti, Roberto; Archetti, Silvana; et al, Journal of Alzheimer's Disease. 1 - 14. 2022. http://dx.doi.org/10.3233/jad-215447 . 10.3233/jad-215447 . published Journal of Alzheimer's Disease

The European Portuguese version of the Oxford Cognitive Screening (OCS-Pt): a screening test for acute stroke patients

Valério, Daniela; Almeida, Jorge; Demeyere, Nele; Lima, Marisa; Nogueira, Joana; Santana, Isabel, Neurological Sciences. 2022. http://dx.doi.org/10.1007/s10072-022-05880-9 . 10.1007/s10072-022-05880-9 . published Neurological Sciences

Rare variants in TP73 in a frontotemporal dementia cohort link this gene with primary progressive aphasia phenotypes

Tábuas-Pereira, Miguel; Santana, Isabel; Almeida, Maria Rosário; Durães, João; Lima, Marisa; Duro, Diana; Kun-Rodrigues, Célia; Bras, Jose; Guerreiro, Rita, European Journal of Neurology. 2022. http://dx.doi.org/10.1111/ene.15248 . 10.1111/ene.15248 . published European Journal of Neurology

Data-driven staging of genetic frontotemporal dementia using multi-modal MRI

McCarthy, Jillian; Borroni, Barbara; Sanchez-Valle, Raquel; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthis; et al, Human Brain Mapping. 2022. http://dx.doi.org/10.1002/hbm.25727 . 10.1002/hbm.25727 . published Human Brain Mapping

Plasma Lipocalin 2 in Alzheimer’s disease: potential utility in the differential diagnosis and relationship with other biomarkers

Hermann, Peter; Villar-Piqué, Anna; Schmitz, Matthias; Schmidt, Christian; Varges, Daniela; Goebel, Stefan; Bunck, Timothy; et al, Alzheimer's Research & Therapy. 1. 14. 2022. http://dx.doi.org/10.1186/s13195-021-00955-9 . 10.1186/s13195-021-00955-9 . Alzheimer's Research & Therapy

Combined Structural MR and Diffusion Tensor Imaging Classify the Presence of Alzheimer’s Disease With the Same Performance as MR Combined With Amyloid Positron Emission Tomography: A Data Integration Approach

Agostinho, Daniel; Caramelo, Francisco; Moreira, Ana Paula; Santana, Isabel; Abrunhosa, Antero; Castelo-Branco, Miguel, Frontiers in Neuroscience. 15. 2022. http://dx.doi.org/10.3389/fnins.2021.638175 . 10.3389/fnins.2021.638175 . Frontiers in Neuroscience

Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum

Jansen, Willemijn J.; Janssen, Olin; Tijms, Betty M.; Vos, Stephanie J. B.; Ossenkoppele, Rik; Visser, Pieter Jelle; Aarsland, Dag; et al, JAMA Neurology. 2022. http://dx.doi.org/10.1001/jamaneurol.2021.5216 . 10.1001/jamaneurol.2021.5216 . JAMA Neurology

Resective Epilepsy Surgery and Respective Histopathological Diagnoses: A Retrospective Cohort Study

Jesus-Ribeiro, Joana; Rebelo, Olinda; Bento, Conceição; Pereira, Cristina; Robalo, Conceição; Rito, Manuel; Pereira, Ricardo; et al, Acta Médica Portuguesa. 2022. http://dx.doi.org/10.20344/amp.18712 . 10.20344/amp.18712 . published Acta Médica Portuguesa

Anomia is present pre-symptomatically in frontotemporal dementia due to MAPT mutations

Bouzigues, Arabella; Russell, Lucy L.; Peakman, Georgia; Bocchetta, Martina; Greaves, Caroline V.; Convery, Rhian S.; Todd, Emily; et al, Journal of Neurology. 4322 - 4332. 8. 269. 2022. http://dx.doi.org/10.1007/s00415-022-11068-0 . 10.1007/s00415-022-11068-0 . published Journal of Neurology

Network structure and transcriptomic vulnerability shape atrophy in frontotemporal dementia

Shafiei, Golia; Bazinet, Vincent; Dadar, Mahsa; Manera, Ana L; Collins, D Louis; Dagher, Alain; Borroni, Barbara; et al, Brain. 2022. http://dx.doi.org/10.1093/brain/awac069 . 10.1093/brain/awac069 . published Brain

Prion-like a-synuclein pathology in the brain of infants with Krabbe disease

Hatton, Christopher; Ghanem, Simona S.; Koss, David J.; Abdi, Ilham Y.; Gibbons, Elizabeth; Guerreiro, Rita; Bras, Jose; et al, Brain. 1257 - 1263. 4. 145. 2022. http://dx.doi.org/10.1093/brain/awac002 . 10.1093/brain/awac002 . Brain

Serum GFAP differentiates Alzheimer’s disease from frontotemporal dementia and predicts MCI-to-dementia conversion

Oeckl, Patrick; Anderl-Straub, Sarah; Von Arnim, Christine A F; Baldeiras, Inês; Diehl-Schmid, Janine; Grimmer, Timo; Halbgebauer, Steffen; et al, Journal of Neurology, Neurosurgery &amp; Psychiatry. 659 - 667. 6. 93. 2022. http://dx.doi.org/10.1136/jnnp-2021-328547 . 10.1136/jnnp-2021-328547 . Journal of Neurology, Neurosurgery &amp; Psychiatry

Longitudinal Cognitive Changes in Genetic Frontotemporal Dementia Within the GENFI Cohort

Poos, Jackie M.; MacDougall, Amy; van den Berg, Esther; Jiskoot, Lize C.; Papma, Janne M.; van der Ende, Emma L.; Seelaar, Harro; et al, Neurology. 3. 99. 2022. http://dx.doi.org/10.1212/wnl.0000000000200384 . 10.1212/wnl.0000000000200384 . Neurology

The landscape of common genetic drivers and <scp>DNA</scp> methylation in low-grade (epilepsy-associated) neuroepithelial tumors: A review

Jesus-Ribeiro, Joana; Rebelo, Olinda; Ribeiro, Ilda Patrícia; Pires, Luís Miguel; Melo, João Daniel; Sales, Francisco; Santana, Isabel; Freire, António; Melo, Joana Barbosa, Neuropathology. 467 - 482. 6. 42. 2022. http://dx.doi.org/10.1111/neup.12846 . 10.1111/neup.12846 . Neuropathology

Frequency and Longitudinal Course of Motor Signs in Genetic Frontotemporal Dementia

Schönecker, Sonja; Martinez-Murcia, Francisco J.; Rauchmann, Boris-Stephan; Franzmeier, Nicolai; Prix, Catharina; Wlasich, Elisabeth; Loosli, Sandra V.; et al, Neurology. 10. 99. 2022. http://dx.doi.org/10.1212/wnl.0000000000200828 . 10.1212/wnl.0000000000200828 . Neurology

Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia

Sogorb-Esteve, Aitana; Nilsson, Johanna; Swift, Imogen J.; Heller, Carolin; Bocchetta, Martina; Russell, Lucy L.; Peakman, Georgia; et al, Alzheimer's Research &amp; Therapy. 1. 14. 2022. http://dx.doi.org/10.1186/s13195-022-01042-3 . 10.1186/s13195-022-01042-3 . Alzheimer's Research &amp; Therapy

Assessing Older Community Members Using a Social Work Tool: Developing an Organizational Response

Ogrin, Rajna; Meyer, Claudia; Karantzoulis, Aliki; Santana, Isabel Jane; Hampson, Ralph, Gerontology and Geriatric Medicine. 8. 2022. http://dx.doi.org/10.1177/23337214221119322 . 10.1177/23337214221119322 . Gerontology and Geriatric Medicine

Longitudinal Cognitive Changes in Genetic Frontotemporal Dementia Within the GENFI Cohort

Poos, Jackie M.; MacDougall, Amy; van den Berg, Esther; Jiskoot, Lize C.; Papma, Janne M.; van der Ende, Emma L.; Seelaar, Harro; et al, Neurology. e281 - e295. 3. 99. 2022. http://dx.doi.org/10.1212/wnl.0000000000200384 . 10.1212/wnl.0000000000200384 . published Neurology

Clinical Application of Pharmacokinetics to Appraise Adherence to Levetiracetam in Portuguese Epileptic Patients

Silva, Rui; Bicker, Joana; Almeida, Anabela; Carona, Andreia; Silva, Ana; Sales, Francisco; Santana, Isabel; Falcão, Amílcar; Fortuna, Ana, Biomedicines. 9. 10. 2022. http://dx.doi.org/10.3390/biomedicines10092127 . 10.3390/biomedicines10092127 . Biomedicines

Temporal dynamics predict symptom onset and cognitive decline in familial frontotemporal dementia

Whiteside, David J.; Malpetti, Maura; Jones, P. Simon; Ghosh, Boyd C. P.; Coyle-Gilchrist, Ian; van Swieten, John C.; Seelaar, Harro; et al, Alzheimer's &amp; Dementia. 1947 - 1962. 5. 19. 2022. http://dx.doi.org/10.1002/alz.12824 . 10.1002/alz.12824 . Alzheimer's &amp; Dementia

Feasibility of a standard cognitive assessment in European academic memory clinics

Grazia, Alice; Altomare, Daniele; Preis, Lukas; Monsch, Andreas U.; Cappa, Stefano F.; Gauthier, Serge; Frölich, Lutz; et al, Alzheimer's &amp; Dementia. 2276 - 2286. 6. 19. 2022. http://dx.doi.org/10.1002/alz.12830 . 10.1002/alz.12830 . Alzheimer's &amp; Dementia

Neurodevelopmental effects of genetic frontotemporal dementia in young adult mutation carriers

Finger, Elizabeth; Malik, Rubina; Bocchetta, Martina; Coleman, Kristy; Graff, Caroline; Borroni, Barbara; Masellis, Mario; et al, Brain. 2120 - 2131. 5. 146. 2022. http://dx.doi.org/10.1093/brain/awac446 . 10.1093/brain/awac446 . Brain

Language impairment in the genetic forms of behavioural variant frontotemporal dementia

Samra, Kiran; MacDougall, Amy M.; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; et al, Journal of Neurology. 1976 - 1988. 4. 270. 2022. http://dx.doi.org/10.1007/s00415-022-11512-1 . 10.1007/s00415-022-11512-1 . Journal of Neurology

Associations between cortical ß-amyloid burden, fornix microstructure and cognitive processing of faces, places, bodies and other visual objects in early Alzheimer's disease

Bourbon-Teles, José; Jorge, Lília; Canário, Nádia; Martins, Ricardo; Santana, Isabel; Castelo-Branco, Miguel, Hippocampus. 112 - 124. 2. 33. 2022. http://dx.doi.org/10.1002/hipo.23493 . 10.1002/hipo.23493 . Hippocampus

Peripheral inflammatory markers during an acute bacterial infection in older patients with and without cognitive dysfunction: A case control study

Regueira, Patrícia; Silva, Ana Rita; Cardoso, Ana Luísa; Cardoso, Ana Maria; Baldeiras, Inês; Santana, Isabel; Cerejeira, Joaquim, Brain, Behavior, &amp; Immunity - Health. 25. 2022. http://dx.doi.org/10.1016/j.bbih.2022.100503 . 10.1016/j.bbih.2022.100503 . Brain, Behavior, &amp; Immunity - Health

Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum

Jansen, Willemijn J.; Janssen, Olin; Tijms, Betty M.; Vos, Stephanie J. B.; Ossenkoppele, Rik; Visser, Pieter Jelle; Aarsland, Dag; et al, JAMA Neurology. 3. 79. 2022. http://dx.doi.org/10.1001/jamaneurol.2021.5216 . 10.1001/jamaneurol.2021.5216 . published JAMA Neurology

Cytogenomic Analysis of Long-Term Epilepsy-Associated Tumors Using an Array-Based CGH Strategy

Jesus-Ribeiro, Joana; Ribeiro, Ilda Patrícia; Pires, Luís Miguel; Paiva, Patrícia; Simões, Sandra; Pereira, Cristina; Robalo, Conceição; et al, Cytogenetic and Genome Research. 28 - 33. 1-2. 162. 2022. http://dx.doi.org/10.1159/000524130 . 10.1159/000524130 . published Cytogenetic and Genome Research

Portuguese version of the CDR plus NACC FTLD: Validation studies

Lima, Marisa; Tábuas-Pereira, Miguel; Durães, João; Faustino, Pedro; Simões, Mário R.; Kukull, Walter; Knopman, David S.; Santana, Isabel, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 1. 14. 2022. http://dx.doi.org/10.1002/dad2.12355 . 10.1002/dad2.12355 . published Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

The Road to Personalized Medicine in Alzheimer’s Disease: The Use of Artificial Intelligence

Silva-Spínola, Anuschka; Baldeiras, Inês; Arrais, Joel P.; Santana, Isabel, Biomedicines. 2. 10. 2022. http://dx.doi.org/10.3390/biomedicines10020315 . 10.3390/biomedicines10020315 . published Biomedicines

Structural brain splitting is a hallmark of Granulin-related frontotemporal dementia

Gazzina, Stefano; Grassi, Mario; Premi, Enrico; Alberici, Antonella; Benussi, Alberto; Archetti, Silvana; Gasparotti, Roberto; et al, Neurobiology of Aging. 94 - 104. 114. 2022. http://dx.doi.org/10.1016/j.neurobiolaging.2022.02.009 . 10.1016/j.neurobiolaging.2022.02.009 . published Neurobiology of Aging

The CBI-R detects early behavioural impairment in genetic frontotemporal dementia

Nelson, Annabel; Russell, Lucy L.; Peakman, Georgia; Convery, Rhian S.; Bouzigues, Arabella; Greaves, Caroline V.; Bocchetta, Martina; et al, Annals of Clinical and Translational Neurology. 644 - 658. 5. 9. 2022. http://dx.doi.org/10.1002/acn3.51544 . 10.1002/acn3.51544 . published Annals of Clinical and Translational Neurology

Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia

Sogorb-Esteve, Aitana; Nilsson, Johanna; Swift, Imogen J.; Heller, Carolin; Bocchetta, Martina; Russell, Lucy L.; Peakman, Georgia; et al, Alzheimer's Research & Therapy. 1. 14. 2022. http://dx.doi.org/10.1186/s13195-022-01042-3 . 10.1186/s13195-022-01042-3 . published Alzheimer's Research & Therapy

Diagnostic accuracy of cerebrospinal fluid biomarkers in genetic prion diseases

Schmitz, Matthias; Villar-Piqué, Anna; Hermann, Peter; Escaramís, Geòrgia; Calero, Miguel; Chen, Cao; Kruse, Niels; et al, Brain. 700 - 712. 2. 145. 2022. http://dx.doi.org/10.1093/brain/awab350 . 10.1093/brain/awab350 . published Brain

Temporal order of clinical and biomarker changes in familial frontotemporal dementia

Staffaroni, Adam M.; Quintana, Melanie; Wendelberger, Barbara; Heuer, Hilary W.; Russell, Lucy L.; Cobigo, Yann; Wolf, Amy; et al, Nature Medicine. 2194 - 2206. 10. 28. 2022. http://dx.doi.org/10.1038/s41591-022-01942-9 . 10.1038/s41591-022-01942-9 . published Nature Medicine

Development of a sensitive trial-ready poly(GP) CSF biomarker assay for C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis

Wilson, Katherine M; Katona, Eszter; Glaria, Idoia; Carcolé, Mireia; Swift, Imogen J; Sogorb-Esteve, Aitana; Heller, Carolin; et al, Journal of Neurology, Neurosurgery &amp; Psychiatry. 761 - 771. 7. 93. 2022. http://dx.doi.org/10.1136/jnnp-2021-328710 . 10.1136/jnnp-2021-328710 . published Journal of Neurology, Neurosurgery &amp; Psychiatry

Impairment of episodic memory in genetic frontotemporal dementia: A GENFI study

Poos, Jackie M.; Russell, Lucy L.; Peakman, Georgia; Bocchetta, Martina; Greaves, Caroline V.; Jiskoot, Lize C.; Ende, Emma L.; et al, Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 1. 13. 2021. http://dx.doi.org/10.1002/dad2.12185 . 10.1002/dad2.12185 . published Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

HPLC method for the determination of antiepileptic drugs in human saliva and its application in therapeutic drug monitoring

Carona, Andreia; Bicker, Joana; Silva, Rui; Silva, Ana; Santana, Isabel; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana, Journal of Pharmaceutical and Biomedical Analysis. 197. 2021. http://dx.doi.org/10.1016/j.jpba.2021.113961 . 10.1016/j.jpba.2021.113961 . published Journal of Pharmaceutical and Biomedical Analysis

Differential early subcortical involvement in genetic FTD within the GENFI cohort

Bocchetta, Martina; Todd, Emily G.; Peakman, Georgia; Cash, David M.; Convery, Rhian S.; Russell, Lucy L.; Thomas, David L.; et al, NeuroImage: Clinical. 30. 2021. http://dx.doi.org/10.1016/j.nicl.2021.102646 . 10.1016/j.nicl.2021.102646 . published NeuroImage: Clinical

Practice effects in genetic frontotemporal dementia and at-risk individuals: a GENFI study

Öijerstedt, Linn; Andersson, Christin; Jelic, Vesna; van Swieten, John Cornelis; Jiskoot, Lize C; Seelaar, Harro; Borroni, Barbara; et al, Journal of Neurology, Neurosurgery & Psychiatry. jnnp - 2021. 2021. http://dx.doi.org/10.1136/jnnp-2021-327005 . 10.1136/jnnp-2021-327005 . published Journal of Neurology, Neurosurgery & Psychiatry

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

Chia, Ruth; Sabir, Marya S.; Bandres-Ciga, Sara; Saez-Atienzar, Sara; Reynolds, Regina H.; Gustavsson, Emil; Walton, Ronald L.; et al, Nature Genetics. 2021. http://dx.doi.org/10.1038/s41588-021-00785-3 . 10.1038/s41588-021-00785-3 . published Nature Genetics

Investigating the Spatial Associations Between Amyloid-ß Deposition, Grey Matter Volume, and Neuroinflammation in Alzheimer’s Disease

Jorge, Lília; Martins, Ricardo; Canário, Nádia; Xavier, Carolina; Abrunhosa, Antero; Santana, Isabel; Castelo-Branco, Miguel, Journal of Alzheimer's Disease. 1 - 20. 2021. http://dx.doi.org/10.3233/jad-200840 . 10.3233/jad-200840 . published Journal of Alzheimer's Disease

Neuropsychological features of progranulin-associated frontotemporal dementia: a nested case-control study

Lima, Marisa; Tábuas-Pereira, Miguel; Duro, Diana; Durães, João; Vieira, Daniela; Baldeiras, Inês; Almeida, MariaRosário; Santana, Isabel, Neural Regeneration Research. 5. 16. 2021. http://dx.doi.org/10.4103/1673-5374.297082 . 10.4103/1673-5374.297082 . published Neural Regeneration Research

Disease-related cortical thinning in presymptomatic granulin mutation carriers

Borrego-Écija, Sergi; Sala-Llonch, Roser; van Swieten, John; Borroni, Barbara; Moreno, Fermín; Masellis, Mario; Tartaglia, Carmela; et al, NeuroImage: Clinical. 29. 2021. http://dx.doi.org/10.1016/j.nicl.2020.102540 . 10.1016/j.nicl.2020.102540 . published NeuroImage: Clinical

Protective effects of cognitive and brain reserve in multiple sclerosis: Differential roles on social cognition and ‘classic cognition’

Machado, Rita; Lima, Cláudia; d'Almeida, Otília C.; Afonso, Ana; Macário, Carmo; Castelo-Branco, Miguel; Sousa, Lívia; Santana, Isabel; Batista, Sónia, Multiple Sclerosis and Related Disorders. 48. 2021. http://dx.doi.org/10.1016/j.msard.2020.102716 . 10.1016/j.msard.2020.102716 . published Multiple Sclerosis and Related Disorders

Progression of Behavioral Disturbances and Neuropsychiatric Symptoms in Patients With Genetic Frontotemporal Dementia

Benussi, Alberto; Premi, Enrico; Gazzina, Stefano; Brattini, Chiara; Bonomi, Elisa; Alberici, Antonella; Jiskoot, Lize; et al, JAMA Network Open. 1. 4. 2021. http://dx.doi.org/10.1001/jamanetworkopen.2020.30194 . 10.1001/jamanetworkopen.2020.30194 . published JAMA Network Open

A data-driven disease progression model of fluid biomarkers in genetic frontotemporal dementia

van der Ende, Emma L; Bron, Esther E; Poos, Jackie M; Jiskoot, Lize C; Panman, Jessica L; Papma, Janne M; Meeter, Lieke H; et al, Brain. 2021. http://dx.doi.org/10.1093/brain/awab382 . 10.1093/brain/awab382 . published Brain

Development and application of an HPLC-DAD technique for human plasma concentration monitoring of perampanel and lamotrigine in drug-resistant epileptic patients

Sabença, Rosa; Bicker, Joana; Silva, Rui; Carona, Andreia; Silva, Ana; Santana, Isabel; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana, Journal of Chromatography B. 1162. 2021. http://dx.doi.org/10.1016/j.jchromb.2020.122491 . 10.1016/j.jchromb.2020.122491 . published Journal of Chromatography B

Modelling the cascade of biomarker changes in GRN-related frontotemporal dementia

Panman, Jessica L; Venkatraghavan, Vikram; van der Ende, Emma L; Steketee, Rebecca M E; Jiskoot, Lize C; Poos, Jackie M; Dopper, Elise G P; et al, Journal of Neurology, Neurosurgery & Psychiatry. jnnp - 2020. 2021. http://dx.doi.org/10.1136/jnnp-2020-323541 . 10.1136/jnnp-2020-323541 . published Journal of Neurology, Neurosurgery & Psychiatry

Outcomes on Social and Classic Cognition in adults with Pediatric-onset Multiple Sclerosis

Massano, Catarina; Lima, Marisa; Monteiro, Isabel; Machado, Rita; Correia, Inês; Nunes, Carla Cecília; Macário, Carmo; et al, Multiple Sclerosis and Related Disorders. 53. 2021. http://dx.doi.org/10.1016/j.msard.2021.103071 . 10.1016/j.msard.2021.103071 . published Multiple Sclerosis and Related Disorders

Stratifying the Presymptomatic Phase of Genetic Frontotemporal Dementia by Serum NfL and pNfH: A Longitudinal Multicentre Study

Wilke, Carlo; Reich, Selina; Swieten, John C.; Borroni, Barbara; Sanchez-Valle, Raquel; Moreno, Fermin; Laforce, Robert; et al, Annals of Neurology. 33 - 47. 1. 91. 2021. http://dx.doi.org/10.1002/ana.26265 . 10.1002/ana.26265 . published Annals of Neurology

Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration

Rojas, Julio C.; Wang, Ping; Staffaroni, Adam M.; Heller, Carolin; Cobigo, Yann; Wolf, Amy; Goh, Sheng-Yang M.; et al, Neurology. e2296 - e2312. 18. 96. 2021. http://dx.doi.org/10.1212/wnl.0000000000011848 . 10.1212/wnl.0000000000011848 . published Neurology

Conceptual framework for the definition of preclinical and prodromal frontotemporal dementia

Benussi, Alberto; Alberici, Antonella; Samra, Kiran; Russell, Lucy L.; Greaves, Caroline V.; Bocchetta, Martina; Ducharme, Simon; et al, Alzheimer's &amp; Dementia. 1408 - 1423. 7. 18. 2021. http://dx.doi.org/10.1002/alz.12485 . 10.1002/alz.12485 . published Alzheimer's &amp; Dementia

Cognitive Trajectories Following Acute Infection in Older Patients With and Without Cognitive Impairment: An 1-Year Follow-Up Study

Silva, Ana Rita; Regueira, Patrícia; Cardoso, Ana Luísa; Baldeiras, Inês; Santana, Isabel; Cerejeira, Joaquim, Frontiers in Psychiatry. 12. 2021. http://dx.doi.org/10.3389/fpsyt.2021.754489 . 10.3389/fpsyt.2021.754489 . Frontiers in Psychiatry

Comparison of clinical rating scales in genetic frontotemporal dementia within the GENFI cohort

Peakman, Georgia; Russell, Lucy L; Convery, Rhian S; Nicholas, Jennifer M; Van Swieten, John C; Jiskoot, Lize C; Moreno, Fermin; et al, Journal of Neurology, Neurosurgery & Psychiatry. jnnp - 2021. 2021. http://dx.doi.org/10.1136/jnnp-2021-326868 . 10.1136/jnnp-2021-326868 . published Journal of Neurology, Neurosurgery & Psychiatry

Toulouse-Piéron Cancellation Test: Normative scores for the portuguese population

Marisa Lima; Élia Baeta; Diana Duro; Miguel Tábuas-Pereira; Daniela Valério; Sandra Freitas; Mário R. Simões; Isabel Santana, Applied Neuropsychology: Adult. 1 - 7. 2021. https://doi.org/10.1080/23279095.2021.1918694 . 10.1080/23279095.2021.1918694 . Applied Neuropsychology: Adult

The Revised Self-Monitoring Scale detects early impairment of social cognition in genetic frontotemporal dementia within the GENFI cohort

Franklin, Hannah D.; Russell, Lucy L.; Peakman, Georgia; Greaves, Caroline V.; Bocchetta, Martina; Nicholas, Jennifer; Poos, Jackie; et al, Alzheimer's Research & Therapy. 1. 13. 2021. http://dx.doi.org/10.1186/s13195-021-00865-w . 10.1186/s13195-021-00865-w . published Alzheimer's Research & Therapy

PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice

Messerschmidt, Clemens; Foddis, Marco; Blumenau, Sonja; Müller, Susanne; Bentele, Kajetan; Holtgrewe, Manuel; Kun-Rodrigues, Celia; et al, Scientific Reports. 1. 11. 2021. http://dx.doi.org/10.1038/s41598-021-84919-x . 10.1038/s41598-021-84919-x . published Scientific Reports

Serum neurofilament light chain as a surrogate of cognitive decline in sporadic and familial frontotemporal dementia

Silva-Spínola, Anuschka; Lima, Marisa; Leitão, Maria João; Durães, João; Tábuas-Pereira, Miguel; Almeida, Maria Rosário; Santana, Isabel; Baldeiras, Inês, European Journal of Neurology. 2021. http://dx.doi.org/10.1111/ene.15058 . 10.1111/ene.15058 . published European Journal of Neurology

A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study

Bergström, Sofia; Öijerstedt, Linn; Remnestål, Julia; Olofsson, Jennie; Ullgren, Abbe; Seelaar, Harro; van Swieten, John C.; et al, Molecular Neurodegeneration. 1. 16. 2021. http://dx.doi.org/10.1186/s13024-021-00499-4 . 10.1186/s13024-021-00499-4 . Molecular Neurodegeneration

Knowing how to do it or doing it? A double dissociation between tool-gesture production and tool-gesture knowledge

Valério, Daniela; Santana, Isabel; Aguiar de Sousa, Diana; Schu, Guilherme; Leal, Gabriela; Pavão Martins, Isabel; Almeida, Jorge, Cortex. 449 - 464. 141. 2021. http://dx.doi.org/10.1016/j.cortex.2021.05.008 . 10.1016/j.cortex.2021.05.008 . published Cortex

Dissemination in time and space in presymptomatic granulin mutation carriers: a GENFI spatial chronnectome study

Premi, Enrico; Giunta, Marcello; Iraji, Armin; Rachakonda, Srinivas; Calhoun, Vince D.; Gazzina, Stefano; Benussi, Alberto; et al, Neurobiology of Aging. 155 - 167. 108. 2021. http://dx.doi.org/10.1016/j.neurobiolaging.2021.09.001 . 10.1016/j.neurobiolaging.2021.09.001 . published Neurobiology of Aging

Vitamin D deficiency in a Portuguese epilepsy cohort: who is at risk and how to treat

Cunha, Inês Antunes; Saraiva, Ana MR.; Lopes, Pedro; Jesus-Ribeiro, Joana; Duarte, Cátia; Leitão, Fátima; Sales, Francisco; Santana, Isabel; Bento, Conceição, Epileptic Disorders. 291 - 298. 2. 23. 2021. http://dx.doi.org/10.1684/epd.2021.1268 . 10.1684/epd.2021.1268 . published Epileptic Disorders

Identification of a novel mutation in MEF2C gene in an atypical patient with frontotemporal lobar degeneration

Adrião, Andreia; Santana, Isabel; Ribeiro, Carolina; Cancela, M. Leonor; Conceição, Natércia; Grazina, Manuela, Neurological Sciences. 2021. http://dx.doi.org/10.1007/s10072-021-05269-0 . 10.1007/s10072-021-05269-0 . published Neurological Sciences

Characterizing the Clinical Features and Atrophy Patterns of MAPT-Related Frontotemporal Dementia With Disease Progression Modeling

Young, Alexandra L.; Bocchetta, Martina; Russell, Lucy L.; Convery, Rhian S.; Peakman, Georgia; Todd, Emily; Cash, David M.; et al, Neurology. e941 - e952. 9. 97. 2021. http://dx.doi.org/10.1212/wnl.0000000000012410 . 10.1212/wnl.0000000000012410 . published Neurology

Single Word Repetition Predicts Long-Term Outcome of Aphasia Caused by an Ischemic Stroke

Tábuas-Pereira, Miguel; Beato-Coelho, José; Ribeiro, Joana; Nogueira, Ana Rita; Cruz, Luis; Silva, Fernando; Sargento-Freitas, João; Cordeiro, Gustavo; Santana, Isabel, Journal of Stroke and Cerebrovascular Diseases. 2. 29. 2020. http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.104566 . 10.1016/j.jstrokecerebrovasdis.2019.104566 . published Journal of Stroke and Cerebrovascular Diseases

A new tetra-plex fluorimetric assay for the quantification of cerebrospinal fluid ß-amyloid42, total-tau, phospho-tau and a-synuclein in the differential diagnosis of neurodegenerative dementia

Diaz-Lucena, Daniela; Escaramis, Geòrgia; Villar-Piqué, Anna; Hermann, Peter; Schmitz, Matthias; Varges, Daniela; Santana, Isabel; et al, Journal of Neurology. 2567 - 2581. 9. 267. 2020. http://dx.doi.org/10.1007/s00415-020-09870-9 . 10.1007/s00415-020-09870-9 . published Journal of Neurology

Incidental findings in peer neurological examination

Reis Carneiro, Diogo; Tábuas-Pereira, Miguel; Santana, Isabel, Journal of the Neurological Sciences. 417. 2020. http://dx.doi.org/10.1016/j.jns.2020.117065 . 10.1016/j.jns.2020.117065 . published Journal of the Neurological Sciences

Early symptoms in symptomatic and preclinical genetic frontotemporal lobar degeneration

Tavares, Tamara Paulo; Mitchell, Derek G V; Coleman, Kristy KL; Coleman, Brenda L; Shoesmith, Christen L; Butler, Christopher R; Santana, Isabel; et al, Journal of Neurology, Neurosurgery & Psychiatry. 975 - 984. 9. 91. 2020. http://dx.doi.org/10.1136/jnnp-2020-322987 . 10.1136/jnnp-2020-322987 . published Journal of Neurology, Neurosurgery & Psychiatry

Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia

van der Ende, Emma L; Xiao, Meifang; Xu, Desheng; Poos, Jackie M; Panman, Jessica L; Jiskoot, Lize C; Meeter, Lieke H; et al, Journal of Neurology, Neurosurgery & Psychiatry. 612 - 621. 6. 91. 2020. http://dx.doi.org/10.1136/jnnp-2019-322493 . 10.1136/jnnp-2019-322493 . published Journal of Neurology, Neurosurgery & Psychiatry

C-reactive protein as a predictor of mild cognitive impairment conversion into Alzheimer's disease dementia

Fernandes, Andreia; Tábuas-Pereira, Miguel; Duro, Diana; Lima, Marisa; Gens, Helena; Santiago, Beatriz; Durães, João; et al, Experimental Gerontology. 2020. http://dx.doi.org/10.1016/j.exger.2020.111004 . 10.1016/j.exger.2020.111004 . published Experimental Gerontology

Neuropsychological Contribution to Predict Conversion to Dementia in Patients with Mild Cognitive Impairment Due to Alzheimer’s Disease

Silva, Dina; Cardoso, Sandra; Guerreiro, Manuela; Maroco, João; Mendes, Tiago; Alves, Luísa; Nogueira, Joana; et al, Journal of Alzheimer's Disease. 1 - 12. 2020. http://dx.doi.org/10.3233/jad-191133 . 10.3233/jad-191133 . Journal of Alzheimer's Disease

Faster Cortical Thinning and Surface Area Loss in Presymptomatic and Symptomatic C9orf72 Repeat Expansion Adult Carriers

Le Blanc, Gabriella; Jetté Pomerleau, Vincent; McCarthy, Jillian; Borroni, Barbara; van Swieten, John; Galimberti, Daniela; Sanchez-Valle, Raquel; et al, Annals of Neurology. 2020. http://dx.doi.org/10.1002/ana.25748 . 10.1002/ana.25748 . published Annals of Neurology

Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia

Llorens, Franc; Hermann, Peter; Villar-Piqué, Anna; Diaz-Lucena, Daniela; Nägga, Katarina; Hansson, Oskar; Santana, Isabel; et al, Nature Communications. 1. 11. 2020. http://dx.doi.org/10.1038/s41467-020-14373-2 . 10.1038/s41467-020-14373-2 . published Nature Communications

Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study

Moore, Katrina M; Nicholas, Jennifer; Grossman, Murray; McMillan, Corey T; Irwin, David J; Massimo, Lauren; Van Deerlin, Vivianna M; et al, The Lancet Neurology. 145 - 156. 2. 19. 2020. http://dx.doi.org/10.1016/s1474-4422(19)30394-1 . 10.1016/s1474-4422(19)30394-1 . published The Lancet Neurology

A modified Camel and Cactus Test detects presymptomatic semantic impairment in genetic frontotemporal dementia within the GENFI cohort

Moore, Katrina; Convery, Rhian; Bocchetta, Martina; Neason, Mollie; Cash, David M.; Greaves, Caroline; Russell, Lucy L.; et al, Applied Neuropsychology: Adult. 1 - 8. 2020. http://dx.doi.org/10.1080/23279095.2020.1716357 . 10.1080/23279095.2020.1716357 . published Applied Neuropsychology: Adult

Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies

Orme, Tatiana; Hernandez, Dena; Ross, Owen A.; Kun-Rodrigues, Celia; Darwent, Lee; Shepherd, Claire E.; Parkkinen, Laura; et al, Acta Neuropathologica Communications. 1. 8. 2020. http://dx.doi.org/10.1186/s40478-020-0879-z . 10.1186/s40478-020-0879-z . published Acta Neuropathologica Communications

Neuropsychological profile of amyloid-positive versus amyloid-negative amnestic Mild Cognitive Impairment

Alves, Luísa; Cardoso, Sandra; Silva, Dina; Mendes, Tiago; Marôco, João; Nogueira, Joana; Lima, Marisa; et al, Journal of Neuropsychology. 2020. http://dx.doi.org/10.1111/jnp.12218 . 10.1111/jnp.12218 . published Journal of Neuropsychology

Face-Specific Perceptual Distortions Reveal A View- and Orientation-Independent Face Template

Almeida, Jorge; Freixo, Andreia; Tábuas-Pereira, Miguel; Herald, Sarah B.; Valério, Daniela; Schu, Guilherme; Duro, Diana; et al, Current Biology. 2020. http://dx.doi.org/10.1016/j.cub.2020.07.067 . 10.1016/j.cub.2020.07.067 . published Current Biology

CYLD variants in frontotemporal dementia associated with severe memory impairment in a Portuguese cohort

Tábuas-Pereira, Miguel; Santana, Isabel; Kun-Rodrigues, Célia; Bras, Jose; Guerreiro, Rita, Brain. e67 - e67. 8. 143. 2020. http://dx.doi.org/10.1093/brain/awaa183 . 10.1093/brain/awaa183 . published Brain

Biomarker counseling, disclosure of diagnosis and follow-up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey

Frederiksen, Kristian S.; Nielsen, Thomas R.; Appollonio, Ildebrando; Andersen, Birgitte Bo; Riverol, Mario; Boada, Mercè; Ceccaldi, Mathieu; et al, International Journal of Geriatric Psychiatry. 2020. http://dx.doi.org/10.1002/gps.5427 . 10.1002/gps.5427 . published International Journal of Geriatric Psychiatry

The temporal stability of premorbid intelligence: A non-clinical 10-year follow-up study using the Irregular Word Reading Test (TeLPI)

Nogueira, J.; Gerardo, B.; Alves, L.; Santana, I.; Simões, M. R.; Freitas, S., Applied Neuropsychology: Adult. 1 - 6. 2020. http://dx.doi.org/10.1080/23279095.2020.1817744 . 10.1080/23279095.2020.1817744 . published Applied Neuropsychology: Adult

Estimates of Geriatric Delirium Frequency in Noncardiac Surgeries and Its Evaluation Across the Years: A Systematic Review and Meta-analysis

Silva, Ana Rita; Regueira, Patrícia; Albuquerque, Elisabete; Baldeiras, Inês; Cardoso, Ana Luísa; Santana, Isabel; Cerejeira, Joaquim, Journal of the American Medical Directors Association. 2020. http://dx.doi.org/10.1016/j.jamda.2020.08.017 . 10.1016/j.jamda.2020.08.017 . published Journal of the American Medical Directors Association

Alzheimer’s Disease Genetics: Review of Novel Loci Associated with Disease

Tábuas-Pereira, Miguel; Santana, Isabel; Guerreiro, Rita; Brás, José, Current Genetic Medicine Reports. 1 - 16. 1. 8. 2020. http://dx.doi.org/10.1007/s40142-020-00182-y . 10.1007/s40142-020-00182-y . Current Genetic Medicine Reports

Patients with progranulin mutations overlap with the progressive dysexecutive syndrome: towards the definition of a frontoparietal dementia phenotype

Tábuas-Pereira, Miguel; Almeida, Maria Rosário; Duro, Diana; Lima, Marisa; Durães, João; Guerreiro, Rita; Brás, José; Baldeiras, Inês; Santana, Isabel, Brain Communications. 2. 2. 2020. http://dx.doi.org/10.1093/braincomms/fcaa126 . 10.1093/braincomms/fcaa126 . published Brain Communications

Increased C-X-C Motif Chemokine Ligand 12 Levels in Cerebrospinal Fluid as a Candidate Biomarker in Sporadic Amyotrophic Lateral Sclerosis

Andrés-Benito, Pol; Povedano, Mònica; Domínguez, Raúl; Marco, Carla; Colomina, Maria J.; López-Pérez, Óscar; Santana, Isabel; et al, International Journal of Molecular Sciences. 22. 21. 2020. http://dx.doi.org/10.3390/ijms21228680 . 10.3390/ijms21228680 . published International Journal of Molecular Sciences

APOE ¿4-TOMM40L Haplotype Increases the Risk of Mild Cognitive Impairment Conversion to Alzheimer’s Disease

Cardoso, Remy; Lemos, Carolina; Oliveiros, Bárbara; Almeida, Maria Rosário; Baldeiras, Inês; Pereira, Cláudia Fragão; Santos, Ana; et al, Journal of Alzheimer's Disease. 587 - 601. 2. 78. 2020. http://dx.doi.org/10.3233/jad-200556 . 10.3233/jad-200556 . published Journal of Alzheimer's Disease

Brain functional network integrity sustains cognitive function despite atrophy in presymptomatic genetic frontotemporal dementia

Tsvetanov, Kamen A.; Gazzina, Stefano; Jones, P. Simon; Swieten, John; Borroni, Barbara; Sanchez-Valle, Raquel; Moreno, Fermin; et al, Alzheimer's & Dementia. 500 - 514. 3. 17. 2020. http://dx.doi.org/10.1002/alz.12209 . 10.1002/alz.12209 . published Alzheimer's & Dementia

Early-onset phenotype of bi-allelic GRN mutations

Neuray, Caroline; Sultan, Tipu; Alvi, Javeira Raza; Franca, Marcondes C; Assmann, Birgit; Wagner, Matias; Canafoglia, Laura; et al, Brain. e22 - e22. 2. 144. 2020. http://dx.doi.org/10.1093/brain/awaa414 . 10.1093/brain/awaa414 . published Brain

Pathophysiology of Blood–Brain Barrier Permeability Throughout the Different Stages of Ischemic Stroke and Its Implication on Hemorrhagic Transformation and Recovery

Bernardo-Castro, Sara; Sousa, João André; Brás, Ana; Cecília, Carla; Rodrigues, Bruno; Almendra, Luciano; Machado, Cristina; et al, Frontiers in Neurology. 11. 2020. http://dx.doi.org/10.3389/fneur.2020.594672 . 10.3389/fneur.2020.594672 . published Frontiers in Neurology

Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia

Heller, Carolin; Foiani, Martha S; Moore, Katrina; Convery, Rhian; Bocchetta, Martina; Neason, Mollie; Cash, David M; et al, Journal of Neurology, Neurosurgery & Psychiatry. 263 - 270. 3. 91. 2020. http://dx.doi.org/10.1136/jnnp-2019-321954 . 10.1136/jnnp-2019-321954 . published Journal of Neurology, Neurosurgery & Psychiatry

Apathy in presymptomatic genetic frontotemporal dementia predicts cognitive decline and is driven by structural brain changes

Malpetti, Maura; Jones, P. Simon; Tsvetanov, Kamen A.; Rittman, Timothy; Swieten, John C.; Borroni, Barbara; Sanchez-Valle, Raquel; et al, Alzheimer's & Dementia. 2020. http://dx.doi.org/10.1002/alz.12252 . 10.1002/alz.12252 . published Alzheimer's & Dementia

Abnormal pain perception is associated with thalamo-cortico-striatal atrophy in C9orf72 expansion carriers in the GENFI cohort

Convery, Rhian S; Bocchetta, Martina; Greaves, Caroline V; Moore, Katrina M; Cash, David M; Van Swieten, John; Moreno, Fermin; et al, Journal of Neurology, Neurosurgery & Psychiatry. jnnp - 2020. 2020. http://dx.doi.org/10.1136/jnnp-2020-323279 . 10.1136/jnnp-2020-323279 . published Journal of Neurology, Neurosurgery & Psychiatry

Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study

van Maurik, Ingrid S; Vos, Stephanie J; Bos, Isabelle; Bouwman, Femke H; Teunissen, Charlotte E; Scheltens, Philip; Barkhof, Frederik; et al, The Lancet Neurology. 1034 - 1044. 11. 18. 2019. http://dx.doi.org/10.1016/s1474-4422(19)30283-2 . 10.1016/s1474-4422(19)30283-2 . published The Lancet Neurology

Increased CSF tau is associated with a higher risk of seizures in patients with Alzheimer's disease

Tábuas-Pereira, Miguel; Durães, João; Lopes, Joana; Sales, Francisco; Bento, Conceição; Duro, Diana; Santiago, Beatriz; et al, Epilepsy & Behavior. 207 - 209. 98. 2019. http://dx.doi.org/10.1016/j.yebeh.2019.06.033 . 10.1016/j.yebeh.2019.06.033 . published Epilepsy & Behavior

Can Subjective Memory Complaints Identify Aß Positive and Aß Negative Amnestic Mild Cognitive Impairment Patients?

Mendes, Tiago; Cardoso, Sandra; Guerreiro, Manuela; Maroco, João; Silva, Dina; Alves, Luísa; Schmand, Ben; et al, Journal of Alzheimer's Disease. 1103 - 1111. 4. 70. 2019. http://dx.doi.org/10.3233/jad-190414 . 10.3233/jad-190414 . published Journal of Alzheimer's Disease

Education modulates brain maintenance in presymptomatic frontotemporal dementia

Gazzina, Stefano; Grassi, Mario; Premi, Enrico; Cosseddu, Maura; Alberici, Antonella; Archetti, Silvana; Gasparotti, Roberto; et al, Journal of Neurology, Neurosurgery & Psychiatry. 1124 - 1130. 10. 90. 2019. http://dx.doi.org/10.1136/jnnp-2019-320439 . 10.1136/jnnp-2019-320439 . published Journal of Neurology, Neurosurgery & Psychiatry

Retinal texture biomarkers may help to discriminate between Alzheimer’s, Parkinson’s, and healthy controls

Nunes, Ana; Silva, Gilberto; Duque, Cristina; Januário, Cristina; Santana, Isabel; Ambrósio, António Francisco; Castelo-Branco, Miguel; Bernardes, Rui, PLOS ONE. 6. 14. 2019. http://dx.doi.org/10.1371/journal.pone.0218826 . 10.1371/journal.pone.0218826 . published PLOS ONE

Semi-quantification and grading of amyloid PET: A project of the European Alzheimer's Disease Consortium (EADC)

Chincarini, A.; Peira, E.; Morbelli, S.; Pardini, M.; Bauckneht, M.; Arbizu, J.; Castelo-Branco, M.; et al, NeuroImage: Clinical. 23. 2019. http://dx.doi.org/10.1016/j.nicl.2019.101846 . 10.1016/j.nicl.2019.101846 . published NeuroImage: Clinical

Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study

Lleó, Alberto; Alcolea, Daniel; Martínez-Lage, Pablo; Scheltens, Philip; Parnetti, Lucilla; Poirier, Judes; Simonsen, Anja H.; et al, Alzheimer's & Dementia. 742 - 753. 6. 15. 2019. http://dx.doi.org/10.1016/j.jalz.2019.01.015 . 10.1016/j.jalz.2019.01.015 . published Alzheimer's & Dementia

Heritability and genetic variance of dementia with Lewy bodies

Guerreiro, Rita; Escott-Price, Valentina; Hernandez, Dena G.; Kun-Rodrigues, Celia; Ross, Owen A.; Orme, Tatiana; Neto, Joao Luis; et al, Neurobiology of Disease. 492 - 501. 127. 2019. http://dx.doi.org/10.1016/j.nbd.2019.04.004 . 10.1016/j.nbd.2019.04.004 . published Neurobiology of Disease

The inner fluctuations of the brain in presymptomatic Frontotemporal Dementia: The chronnectome fingerprint

Premi, Enrico; Calhoun, Vince D.; Diano, Matteo; Gazzina, Stefano; Cosseddu, Maura; Alberici, Antonella; Archetti, Silvana; et al, NeuroImage. 645 - 654. 189. 2019. http://dx.doi.org/10.1016/j.neuroimage.2019.01.080 . 10.1016/j.neuroimage.2019.01.080 . published NeuroImage

Association between Adipokines and Biomarkers of Alzheimer’s Disease: A Cross-Sectional Study

Letra, Liliana; Matafome, Paulo; Rodrigues, Tiago; Duro, Diana; Lemos, Raquel; Baldeiras, Inês; Patrício, Miguel; et al, Journal of Alzheimer's Disease. 725 - 735. 2. 67. 2019. http://dx.doi.org/10.3233/jad-180669 . 10.3233/jad-180669 . published Journal of Alzheimer's Disease

Interplay Between Macular Retinal Changes and White Matter Integrity in Early Alzheimer’s Disease

Alves, Carolina; Jorge, Lília; Canário, Nádia; Santiago, Beatriz; Santana, Isabel; Castelhano, João; Ambrósio, António Francisco; Bernardes, Rui; Castelo-Branco, Miguel, Journal of Alzheimer's Disease. 723 - 732. 3. 70. 2019. http://dx.doi.org/10.3233/jad-190152 . 10.3233/jad-190152 . published Journal of Alzheimer's Disease

Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study

van der Ende, Emma L; Meeter, Lieke H; Poos, Jackie M; Panman, Jessica L; Jiskoot, Lize C; Dopper, Elise G P; Papma, Janne M; et al, The Lancet Neurology. 1103 - 1111. 12. 18. 2019. http://dx.doi.org/10.1016/s1474-4422(19)30354-0 . 10.1016/s1474-4422(19)30354-0 . published The Lancet Neurology

Clock drawing test in mild cognitive impairment: Correlation with cerebral perfusion in single-photon emission computed tomography.

Duro, Diana; Cerveira, Pedro; Santiago, Beatriz; Cunha, Maria João; Pedroso de Lima, João Manuel; Botelho, Maria Amália; Santana, Isabel, Neuropsychology. 617 - 632. 5. 33. 2019. http://dx.doi.org/10.1037/neu0000549 . 10.1037/neu0000549 . published Neuropsychology

Clinical validation of the Lumipulse G cerebrospinal fluid assays for routine diagnosis of Alzheimer’s disease

Leitão, Maria João; Silva-Spínola, Anuschka; Santana, Isabel; Olmedo, Veronica; Nadal, Alicia; Le Bastard, Nathalie; Baldeiras, Inês, Alzheimer's Research & Therapy. 1. 11. 2019. http://dx.doi.org/10.1186/s13195-019-0550-8 . 10.1186/s13195-019-0550-8 . published Alzheimer's Research & Therapy

Validation study of the Toulouse-Piéron cancellation test for Portuguese patients with Mild Cognitive Impairment and Alzheimer's disease

Lima, Marisa; Duro, Diana; Freitas, Sandra; Simões, Mário; Santana, I, Sinapse. 26 - 35. 1-2. 19. 2019. http://www.sinapse.pt/section.php?id=29 . published Sinapse

Lower CSF Amyloid-Beta1–42 Predicts a Higher Mortality Rate in Frontotemporal Dementia

Vieira, Daniela; Durães, João; Baldeiras, Inês; Santiago, Beatriz; Duro, Diana; Lima, Marisa; Leitão, Maria João; Tábuas-Pereira, Miguel; Santana, Isabel, Diagnostics. 4. 9. 2019. http://dx.doi.org/10.3390/diagnostics9040162 . 10.3390/diagnostics9040162 . published Diagnostics

Validity and Clinical Utility of Different Clock Drawing Test Scoring Systems in Multiple Forms of Dementia

Duro, Diana; Tábuas-Pereira, Miguel; Freitas, Sandra; Santiago, Beatriz; Botelho, Maria Amália; Santana, Isabel, Journal of Geriatric Psychiatry and Neurology. 114 - 122. 3. 31. 2018. http://dx.doi.org/10.1177/0891988718774432 . 10.1177/0891988718774432 . published Journal of Geriatric Psychiatry and Neurology

Using the Rasch analysis for the psychometric validation of the Irregular Word Reading Test (TeLPI): A Portuguese test for the assessment of premorbid intelligence

Freitas, Sandra; Prieto, Gerardo; Simões, Mário R.; Nogueira, Joana; Santana, Isabel; Martins, Cristina; Alves, Lara, The Clinical Neuropsychologist. 60 - 76. sup1. 32. 2018. http://dx.doi.org/10.1080/13854046.2018.1468481 . 10.1080/13854046.2018.1468481 . published The Clinical Neuropsychologist

Prevalence of the apolipoprotein E e4 allele in amyloid ß positive subjects across the spectrum of Alzheimer's disease

Mattsson, Niklas; Groot, Colin; Jansen, Willemijn J.; Landau, Susan M.; Villemagne, Victor L.; Engelborghs, Sebastiaan; Mintun, Mark M.; et al, Alzheimer's & Dementia. 913 - 924. 7. 14. 2018. http://dx.doi.org/10.1016/j.jalz.2018.02.009 . 10.1016/j.jalz.2018.02.009 . published Alzheimer's & Dementia

Escala de Avaliação da Doença de Alzheimer - Subescala Cognitiva (ADAS-Cog): Dados Normativos para a População Portuguesa

Nogueira, Joana; Freitas, Sandra; Duro, Diana; Tábuas-Pereira, Miguel; Guerreiro, Manuela; Almeida, Jorge; Santana, Isabel, Acta Médica Portuguesa. 2. 31. 2018. http://dx.doi.org/10.20344/amp.8859 . 10.20344/amp.8859 . published Acta Médica Portuguesa

Validation study of the Alzheimer’s disease assessment scale–cognitive subscale (ADAS-Cog) for the Portuguese patients with mild cognitive impairment and Alzheimer’s disease

Nogueira, Joana; Freitas, Sandra; Duro, Diana; Almeida, Jorge; Santana, Isabel, The Clinical Neuropsychologist. 46 - 59. sup1. 32. 2018. http://dx.doi.org/10.1080/13854046.2018.1454511 . 10.1080/13854046.2018.1454511 . published The Clinical Neuropsychologist

Addition of the Aß42/40 ratio to the cerebrospinal fluid biomarker profile increases the predictive value for underlying Alzheimer’s disease dementia in mild cognitive impairment

Baldeiras, Inês; Santana, Isabel; Leitão, Maria João; Gens, Helena; Pascoal, Rui; Tábuas-Pereira, Miguel; Beato-Coelho, José; et al, Alzheimer's Research & Therapy. 1. 10. 2018. http://dx.doi.org/10.1186/s13195-018-0362-2 . 10.1186/s13195-018-0362-2 . published Alzheimer's Research & Therapy

Rare nonsynonymous variants in SORT1 are associated with increased risk for frontotemporal dementia

Philtjens, Stéphanie; Van Mossevelde, Sara; van der Zee, Julie; Wauters, Eline; Dillen, Lubina; Vandenbulcke, Mathieu; Vandenberghe, Rik; et al, Neurobiology of Aging. 181.e3 - 181.e10. 66. 2018. http://dx.doi.org/10.1016/j.neurobiolaging.2018.02.011 . 10.1016/j.neurobiolaging.2018.02.011 . published Neurobiology of Aging

Advanced MRI study of migrainous infarction presenting as cortical laminar necrosis – Case report and literature review

Morais, Ricardo; Sobral, Filipe; Cunha, Gil; Brito, Olga; Santana, Isabel, Clinical Neurology and Neurosurgery. 82 - 85. 167. 2018. http://dx.doi.org/10.1016/j.clineuro.2018.02.016 . 10.1016/j.clineuro.2018.02.016 . published Clinical Neurology and Neurosurgery

Cerebrospinal fluid neurofilament light levels in neurodegenerative dementia: Evaluation of diagnostic accuracy in the differential diagnosis of prion diseases

Zerr, Inga; Schmitz, Matthias; Karch, André; Villar-Piqué, Anna; Kanata, Eirini; Golanska, Ewa; Díaz-Lucena, Daniela; et al, Alzheimer's & Dementia. 751 - 763. 6. 14. 2018. http://dx.doi.org/10.1016/j.jalz.2017.12.008 . 10.1016/j.jalz.2017.12.008 . published Alzheimer's & Dementia

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

Guerreiro, Rita; Ross, Owen A; Kun-Rodrigues, Celia; Hernandez, Dena G; Orme, Tatiana; Eicher, John D; Shepherd, Claire E; et al, The Lancet Neurology. 64 - 74. 1. 17. 2018. http://dx.doi.org/10.1016/s1474-4422(17)30400-3 . 10.1016/s1474-4422(17)30400-3 . published The Lancet Neurology

Influence of Butyrylcholinesterase in Progression of Mild Cognitive Impairment to Alzheimer’s Disease

Gabriel, António José; Almeida, Maria Rosário; Ribeiro, Maria Helena; Carneiro, Diogo; Valério, Daniela; Pinheiro, Ana Cristina; Pascoal, Rui; Santana, Isabel; Baldeiras, Inês, Journal of Alzheimer's Disease. 1097 - 1105. 3. 61. 2018. http://dx.doi.org/10.3233/jad-170695 . 10.3233/jad-170695 . published Journal of Alzheimer's Disease

Association of Cerebral Amyloid-ß Aggregation With Cognitive Functioning in Persons Without Dementia

Jansen, Willemijn J.; Ossenkoppele, Rik; Tijms, Betty M.; Fagan, Anne M.; Hansson, Oskar; Klunk, William E.; van der Flier, Wiesje M.; et al, JAMA Psychiatry. 1. 75. 2018. http://dx.doi.org/10.1001/jamapsychiatry.2017.3391 . 10.1001/jamapsychiatry.2017.3391 . published JAMA Psychiatry

Common and rare TBK1 variants in early-onset Alzheimer disease in a European cohort

Verheijen, Jan; van der Zee, Julie; Gijselinck, Ilse; Van den Bossche, Tobi; Dillen, Lubina; Heeman, Bavo; Gómez-Tortosa, Estrella; et al, Neurobiology of Aging. 245.e1 - 245.e7. 62. 2018. http://dx.doi.org/10.1016/j.neurobiolaging.2017.10.012 . 10.1016/j.neurobiolaging.2017.10.012 . published Neurobiology of Aging

No supportive evidence for TIA1 gene mutations in a European cohort of ALS-FTD spectrum patients

Baradaran-Heravi, Yalda; Dillen, Lubina; Nguyen, Hung Phuoc; Van Mossevelde, Sara; Baets, Jonathan; De Jonghe, Peter; Engelborghs, Sebastiaan; et al, Neurobiology of Aging. 293.e9 - 293.e11. 69. 2018. http://dx.doi.org/10.1016/j.neurobiolaging.2018.05.005 . 10.1016/j.neurobiolaging.2018.05.005 . published Neurobiology of Aging

Aphasia Rapid Test: Estudos de Tradução, Adaptação e Validação para a População Portuguesa

Tábuas-Pereira, Miguel; Freitas, Sandra; Beato-Coelho, José; Ribeiro, Joana; Parra, Joana; Martins, Cristina; Silva, Miguel; et al, Acta Médica Portuguesa. 5. 31. 2018. http://dx.doi.org/10.20344/amp.9090 . 10.20344/amp.9090 . published Acta Médica Portuguesa

Underlying Biological Processes in Mild Cognitive Impairment: Amyloidosis Versus Neurodegeneration

Santana, Isabel; Baldeiras, Inês; Santiago, Beatriz; Duro, Diana; Freitas, Sandra; Pereira, Miguel Tábuas; Almeida, Maria Rosário; Oliveira, Catarina Resende, Journal of Alzheimer's Disease. S647 - S657. s1. 64. 2018. http://dx.doi.org/10.3233/jad-179908 . 10.3233/jad-179908 . published Journal of Alzheimer's Disease

The Head Turning Sign in Dementia and Mild Cognitive Impairment: Its Relationship to Cognition, Behavior, and Cerebrospinal Fluid Biomarkers

Durães, João; Tábuas-Pereira, Miguel; Araújo, Rui; Duro, Diana; Baldeiras, Inês; Santiago, Beatriz; Santana, Isabel, Dementia and Geriatric Cognitive Disorders. 42 - 49. 1-2. 46. 2018. http://dx.doi.org/10.1159/000486531 . 10.1159/000486531 . published Dementia and Geriatric Cognitive Disorders

Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aß species

Oliveira, Francisco; Leuzy, Antoine; Castelhano, João; Chiotis, Konstantinos; Hasselbalch, Steen Gregers; Rinne, Juha; Mendonça, Alexandre; et al, NeuroImage: Clinical. 603 - 610. 20. 2018. http://dx.doi.org/10.1016/j.nicl.2018.08.023 . 10.1016/j.nicl.2018.08.023 . published NeuroImage: Clinical

Discriminative capacity and construct validity of the Clock Drawing Test in Mild Cognitive Impairment and Alzheimer’s disease

Duro, Diana; Freitas, Sandra; Tábuas-Pereira, Miguel; Santiago, Beatriz; Botelho, Maria Amália; Santana, Isabel, The Clinical Neuropsychologist. 1159 - 1174. 7. 33. 2018. http://dx.doi.org/10.1080/13854046.2018.1532022 . 10.1080/13854046.2018.1532022 . published The Clinical Neuropsychologist

Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer’s Disease Cerebrospinal Fluid Biomarkers

Ramos de Matos, Mafalda; Ferreira, Catarina; Herukka, Sanna-Kaisa; Soininen, Hilkka; Janeiro, André; Santana, Isabel; Baldeiras, Inês; et al, Journal of Alzheimer's Disease. 639 - 652. 2. 66. 2018. http://dx.doi.org/10.3233/jad-180512 . 10.3233/jad-180512 . published Journal of Alzheimer's Disease

The neural basis of fatigue in multiple sclerosis: a multimodal MRI approach

Novo, Ana Margarida; Batista, Sonia; Alves, Carolina; d’Almeida, Otília C.; Marques, Inês Brás; Macário, Carmo; Santana, Isabel; et al, Neurology: Clinical Practice. 492 - 500. 6. 8. 2018. http://dx.doi.org/10.1212/cpj.0000000000000545 . 10.1212/cpj.0000000000000545 . published Neurology: Clinical Practice

The Quadruple Helix-Based Innovation Model of Reference Sites for Active and Healthy Ageing in Europe: The Ageing@Coimbra Case Study

Malva, João O.; Amado, Alda; Rodrigues, Alexandra; Mota-Pinto, Anabela; Cardoso, Ana F.; Teixeira, Ana M.; Todo-Bom, Ana; et al, Frontiers in Medicine. 5. 2018. http://dx.doi.org/10.3389/fmed.2018.00132 . 10.3389/fmed.2018.00132 . published Frontiers in Medicine

Cerebrospinal Fluid Total Prion Protein in the Spectrum of Prion Diseases

Villar-Piqué, Anna; Schmitz, Matthias; Lachmann, Ingolf; Karch, André; Calero, Olga; Stehmann, Christiane; Sarros, Shannon; et al, Molecular Neurobiology. 2811 - 2821. 4. 56. 2018. http://dx.doi.org/10.1007/s12035-018-1251-1 . 10.1007/s12035-018-1251-1 . published Molecular Neurobiology

Predicting progression of mild cognitive impairment to dementia using neuropsychological data: a supervised learning approach using time windows

Pereira, Telma; Lemos, Luís; Cardoso, Sandra; Silva, Dina; Rodrigues, Ana; Santana, Isabel; de Mendonça, Alexandre; Guerreiro, Manuela; Madeira, Sara C., BMC Medical Informatics and Decision Making. 1. 17. 2017. http://dx.doi.org/10.1186/s12911-017-0497-2 . 10.1186/s12911-017-0497-2 . published BMC Medical Informatics and Decision Making

Clinical Reasoning: A 55-year-old man with rapidly progressive dementia and parkinsonism

Tábuas-Pereira, Miguel; Santana, Isabel; Santo, Gustavo Cordeiro, Neurology. e182 - e187. 15. 89. 2017. http://dx.doi.org/10.1212/wnl.0000000000004495 . 10.1212/wnl.0000000000004495 . published Neurology

Adiponectin and sporadic Alzheimer’s disease: Clinical and molecular links

Letra, Liliana; Rodrigues, Tiago; Matafome, Paulo; Santana, Isabel; Seiça, Raquel, Frontiers in Neuroendocrinology. 1 - 11. 52. 2017. http://dx.doi.org/10.1016/j.yfrne.2017.10.002 . 10.1016/j.yfrne.2017.10.002 . published Frontiers in Neuroendocrinology

Theory of Mind and Executive Functions are Dissociated in Multiple Sclerosis

Batista, Sonia; Freitas, Sandra; Afonso, Ana; Macário, Carmo; Sousa, Lívia; Cunha, Luís; Santana, Isabel, Archives of Clinical Neuropsychology. 541 - 551. 5. 33. 2017. http://dx.doi.org/10.1093/arclin/acx101 . 10.1093/arclin/acx101 . Archives of Clinical Neuropsychology

TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

van der Zee, Julie; Gijselinck, Ilse; Van Mossevelde, Sara; Perrone, Federica; Dillen, Lubina; Heeman, Bavo; Bäumer, Veerle; et al, Human Mutation. 297 - 309. 3. 38. 2017. http://dx.doi.org/10.1002/humu.23161 . 10.1002/humu.23161 . published Human Mutation

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer’s Disease Patients and Controls after Correction for Ventricular Volumes

van Waalwijk van Doorn, Linda J.C.; Gispert, Juan D.; Kuiperij, H. Bea; Claassen, Jurgen A.H.R.; Arighi, Andrea; Baldeiras, Inês; Blennow, Kaj; et al, Journal of Alzheimer's Disease. 543 - 555. 2. 56. 2017. http://dx.doi.org/10.3233/jad-160668 . 10.3233/jad-160668 . published Journal of Alzheimer's Disease

Association between butyrylcholinesterase and cerebrospinal fluid biomarkers in Alzheimer’s disease patients

Gabriel, António José; Almeida, Maria Rosário; Ribeiro, Maria Helena; Durães, João; Tábuas-Pereira, Miguel; Pinheiro, Ana Cristina; Pascoal, Rui; Santana, Isabel; Baldeiras, Inês, Neuroscience Letters. 101 - 106. 641. 2017. http://dx.doi.org/10.1016/j.neulet.2017.01.036 . 10.1016/j.neulet.2017.01.036 . published Neuroscience Letters

The impact of automated hippocampal volumetry on diagnostic confidence in patients with suspected Alzheimer's disease: A European Alzheimer's Disease Consortium study

Bosco, Paolo; Redolfi, Alberto; Bocchetta, Martina; Ferrari, Clarissa; Mega, Anna; Galluzzi, Samantha; Austin, Mark; et al, Alzheimer's & Dementia. 1013 - 1023. 9. 13. 2017. http://dx.doi.org/10.1016/j.jalz.2017.01.019 . 10.1016/j.jalz.2017.01.019 . published Alzheimer's & Dementia

Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer’s disease

De Roeck, Arne; Van den Bossche, Tobi; van der Zee, Julie; Verheijen, Jan; De Coster, Wouter; Van Dongen, Jasper; Dillen, Lubina; et al, Acta Neuropathologica. 475 - 487. 3. 134. 2017. http://dx.doi.org/10.1007/s00401-017-1714-x . 10.1007/s00401-017-1714-x . published Acta Neuropathologica

Disconnection as a mechanism for social cognition impairment in multiple sclerosis

Batista, Sonia; Alves, Carolina; d’Almeida, Otília C.; Afonso, Ana; Félix-Morais, Ricardo; Pereira, João; Macário, Carmo; et al, Neurology. 38 - 45. 1. 89. 2017. http://dx.doi.org/10.1212/wnl.0000000000004060 . 10.1212/wnl.0000000000004060 . published Neurology

Transthyretin stability is critical in assisting beta amyloid clearance- Relevance of transthyretin stabilization in Alzheimer's disease

Alemi, Mobina; Silva, Sara C.; Santana, Isabel; Cardoso, Isabel, CNS Neuroscience & Therapeutics. 605 - 619. 7. 23. 2017. http://dx.doi.org/10.1111/cns.12707 . 10.1111/cns.12707 . published CNS Neuroscience & Therapeutics

The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

Bos, Isabelle; Vos, Stephanie J.; Frölich, Lutz; Kornhuber, Johannes; Wiltfang, Jens; Maier, Wolfgang; Peters, Oliver; et al, Neurobiology of Aging. 33 - 40. 56. 2017. http://dx.doi.org/10.1016/j.neurobiolaging.2017.03.034 . 10.1016/j.neurobiolaging.2017.03.034 . published Neurobiology of Aging

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies

Kun-Rodrigues, Celia; Ross, Owen A.; Orme, Tatiana; Shepherd, Claire; Parkkinen, Laura; Darwent, Lee; Hernandez, Dena; et al, Neurobiology of Aging. 214.e13 - 214.e15. 49. 2017. http://dx.doi.org/10.1016/j.neurobiolaging.2016.08.023 . 10.1016/j.neurobiolaging.2016.08.023 . published Neurobiology of Aging

Construct and diagnostic validities of the Free and Cued Selective Reminding Test in the Alzheimer’s disease spectrum

Lemos, Raquel; Marôco, João; Simões, Mário R.; Santana, Isabel, Journal of Clinical and Experimental Neuropsychology. 913 - 924. 8. 38. 2016. http://dx.doi.org/10.1080/13803395.2016.1176996 . 10.1080/13803395.2016.1176996 . published Journal of Clinical and Experimental Neuropsychology

Sporadic Creutzfeldt–Jakob disease diagnostic accuracy is improved by a new CSF ELISA 14-3-3¿ assay

Leitão, M.J.; Baldeiras, I.; Almeida, M.R.; Ribeiro, M.H.; Santos, A.C.; Ribeiro, M.; Tomás, J.; et al, Neuroscience. 398 - 407. 322. 2016. http://dx.doi.org/10.1016/j.neuroscience.2016.02.057 . 10.1016/j.neuroscience.2016.02.057 . Neuroscience

Portuguese version of Wechsler Memory Scale–3rd edition’s utility with demented elderly adults

Gonçalves, Cátia; Pinho, Maria S.; Cruz, Vítor; Gens, Helena; Oliveira, Fátima; Pais, Joana; Rente, José; Santana, Isabel; Santos, José M., Applied Neuropsychology: Adult. 212 - 225. 3. 24. 2016. http://dx.doi.org/10.1080/23279095.2015.1135440 . 10.1080/23279095.2015.1135440 . published Applied Neuropsychology: Adult

Neuroimaging Correlates of Frontotemporal Dementia Associated with SQSTM1 Mutations

Luis, Elkin; Ortiz, Alexandra; Eudave, Luis; Ortega-Cubero, Sara; Borroni, Barbara; van der Zee, Julie; Gazzina, Stefano; et al, Journal of Alzheimer's Disease. 303 - 313. 1. 53. 2016. http://dx.doi.org/10.3233/jad-160006 . 10.3233/jad-160006 . published Journal of Alzheimer's Disease

Pittsburgh compound B imaging and cerebrospinal fluid amyloid-ß in a multicentre European memory clinic study

Leuzy, Antoine; Chiotis, Konstantinos; Hasselbalch, Steen G.; Rinne, Juha O.; de Mendonça, Alexandre; Otto, Markus; Lleó, Alberto; et al, Brain. 2540 - 2553. 9. 139. 2016. http://dx.doi.org/10.1093/brain/aww160 . 10.1093/brain/aww160 . published Brain

Three-Dimensional Face Recognition in Mild Cognitive Impairment: A Psychophysical and Structural MR Study

Lemos, Raquel; Santana, Isabel; Caetano, Gina; Bernardino, Inês; Morais, Ricardo; Farivar, Reza; Castelo-Branco, Miguel, Journal of the International Neuropsychological Society. 744 - 754. 7. 22. 2016. http://dx.doi.org/10.1017/s135561771600059x . 10.1017/s135561771600059x . published Journal of the International Neuropsychological Society

Portuguese family with the co-occurrence of frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis phenotypes due to progranulin gene mutation

Almeida, Maria R.; Macário, Maria C.; Ramos, Lina; Baldeiras, Inês; Ribeiro, Maria H.; Santana, Isabel, Neurobiology of Aging. 200.e1 - 200.e5. 41. 2016. http://dx.doi.org/10.1016/j.neurobiolaging.2016.02.019 . 10.1016/j.neurobiolaging.2016.02.019 . published Neurobiology of Aging

Prosopagnosia as the Presenting Symptom of Whipple Disease

Tábuas-Pereira, Miguel; Vicente, Margarida; Coelho, Filomena; Santana, Isabel, Cognitive And Behavioral Neurology. 100 - 106. 2. 29. 2016. http://dx.doi.org/10.1097/wnn.0000000000000091 . 10.1097/wnn.0000000000000091 . published Cognitive And Behavioral Neurology

ABCA7 p.G215S as potential protective factor for Alzheimer's disease

Sassi, Celeste; Nalls, Michael A.; Ridge, Perry G.; Gibbs, Jesse R.; Ding, Jinhui; Lupton, Michelle K.; Troakes, Claire; et al, Neurobiology of Aging. 235.e1 - 235.e9. 46. 2016. http://dx.doi.org/10.1016/j.neurobiolaging.2016.04.004 . 10.1016/j.neurobiolaging.2016.04.004 . published Neurobiology of Aging

Mini-Mental State Examination: Screening and diagnosis of cognitive decline, using new normative data

Santana, I; Duro, Diana; Lemos, Raquel; Simões, Mário; Freitas, Sandra, Acta Médica Portuguesa. 240 - 248. 4. 29. 2016. https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6889 . published Acta Médica Portuguesa

MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's disease

Guedes, J.R.; Santana, I.; Cunha, C.; Duro, D.; Almeida, M.R.; Cardoso, A.M.; de Lima, M.C.P.; Cardoso, A.L., Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 7 - 17. 3. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956620147&partnerID=MN8TOARS . 10.1016/j.dadm.2015.11.004 . Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring

The Montreal Cognitive Assessment (MoCA) as a screening test for cognitive dysfunction in multiple sclerosis

Freitas, Sandra; Batista, Sónia; Afonso, Ana Cristina; Simões, Mário R.; de Sousa, Lívia; Cunha, Luís; Santana, Isabel, Applied Neuropsychology: Adult. 57 - 70. 1. 25. 2016. http://dx.doi.org/10.1080/23279095.2016.1243108 . 10.1080/23279095.2016.1243108 . published Applied Neuropsychology: Adult

CSF Tau proteins reduce misdiagnosis of sporadic Creutzfeldt–Jakob disease suspected cases with inconclusive 14-3-3 result

Leitão, M. J.; Baldeiras, I.; Almeida, M. R.; Ribeiro, M. H.; Santos, A. C.; Ribeiro, M.; Tomás, J.; et al, Journal of Neurology. 1847 - 1861. 9. 263. 2016. http://dx.doi.org/10.1007/s00415-016-8209-x . 10.1007/s00415-016-8209-x . published Journal of Neurology

Impairment of social cognition in multiple sclerosis: Amygdala atrophy is the main predictor

Batista, Sonia; d’Almeida, Otília C; Afonso, Ana; Freitas, Sandra; Macário, Carmo; Sousa, Lívia; Castelo-Branco, Miguel; Santana, Isabel; Cunha, Luís, Multiple Sclerosis Journal. 1358 - 1366. 10. 23. 2016. http://dx.doi.org/10.1177/1352458516680750 . 10.1177/1352458516680750 . published Multiple Sclerosis Journal

Pseudohypoparathyroidism type I-b with neurological involvement is associated with a homozygousPTH1Rmutation

Guerreiro, R.; Brás, J.; Batista, S.; Pires, P.; Ribeiro, M. H.; Almeida, M. R.; Oliveira, C.; Hardy, J.; Santana, I., Genes, Brain and Behavior. 669 - 677. 7. 15. 2016. http://dx.doi.org/10.1111/gbb.12308 . 10.1111/gbb.12308 . published Genes, Brain and Behavior

The epidemiology of dementia and Alzheimer disease in Portugal: Estimations of prevalence and treatment-costs | Epidemiologia da demência e da doença de Alzheimer em Portugal: Estimativas da prevalência e dos encargos financeiros com a medicação

Santana, I.; Farinha, F.; Freitas, S.; Rodrigues, V.; Carvalho, Á., Acta Medica Portuguesa. 182 - 188. 2. 28. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930450663&partnerID=MN8TOARS . Acta Medica Portuguesa

Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage

Vos, S.J.B.; Verhey, F.; Frölich, L.; Kornhuber, J.; Wiltfang, J.; Maier, W.; Peters, O.; et al, Brain. 1327 - 1338. 5. 138. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929363392&partnerID=MN8TOARS . 10.1093/brain/awv029 . Brain

The Portuguese version of Addenbrooke's cognitive examination-revised (ACE-R) in the diagnosis of subcortical vascular dementia and Alzheimers disease

Gonçalves, C.; Pinho, M.S.; Cruz, V.; Pais, J.; Gens, H.; Oliveira, F.; Santana, I.; Rente, J.; Santos, J.M., Aging, Neuropsychology, and Cognition. 473 - 485. 4. 22. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84927799324&partnerID=MN8TOARS . 10.1080/13825585.2014.984652 . Aging, Neuropsychology, and Cognition

The free and cued selective reminding test for predicting progression to Alzheimer's disease in patients with mild cognitive impairment: A prospective longitudinal study

Lemos, R.; Marôco, J.; Simões, M.R.; Santiago, B.; Tomás, J.; Santana, I., Journal of Neuropsychology. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930725382&partnerID=MN8TOARS . 10.1111/jnp.12075 . Journal of Neuropsychology

The use of biomarkers for the etiologic diagnosis of MCI in Europe: An EADC survey

Bocchetta, M.; Galluzzi, S.; Kehoe, P.G.; Aguera, E.; Bernabei, R.; Bullock, R.; Ceccaldi, M.; et al, Alzheimer's and Dementia. 195 - 206.e1. 2. 11. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929751761&partnerID=MN8TOARS . 10.1016/j.jalz.2014.06.006 . Alzheimer's and Dementia

[The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs].

Santana I; Farinha F; Freitas S; Rodrigues V; Carvalho Å, 2015. http://europepmc.org/abstract/med/26061508 .

Free and Cued Selective Reminding Test is superior to the Wechsler Memory Scale in discriminating mild cognitive impairment from Alzheimer's disease

Lemos, R.; Cunha, C.; Marôco, J.; Afonso, A.; Simões, M.R.; Santana, I., Geriatrics and Gerontology International. 961 - 968. 8. 15. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937921570&partnerID=MN8TOARS . 10.1111/ggi.12374 . Geriatrics and Gerontology International

Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases

Lleó, A.; Cavedo, E.; Parnetti, L.; Vanderstichele, H.; Herukka, S.K.; Andreasen, N.; Ghidoni, R.; et al, Nature Reviews Neurology. 41 - 55. 1. 11. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84926244431&partnerID=MN8TOARS . 10.1038/nrneurol.2014.232 . Nature Reviews Neurology

Does Caffeine Consumption Modify Cerebrospinal Fluid Amyloid-ß Levels in Patients with Alzheimer's Disease?

Travassos, M.; Santana, I.; Baldeiras, I.; Tsolaki, M.; Gkatzima, O.; Genc, S.; Yener, G.G.; et al, Journal of Alzheimer's Disease. 1069 - 1078. 4. 47. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939450783&partnerID=MN8TOARS . 10.3233/JAD-150374 . Journal of Alzheimer's Disease

Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: A European early-onset dementia consortium study

Cuyvers, E.; van der Zee, J.; Bettens, K.; Engelborghs, S.; Vandenbulcke, M.; Robberecht, C.; Dillen, L.; et al, Neurobiology of Aging. 2005.e15 - 2005.e22. 5. 36. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84933180683&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2015.02.014 . Neurobiology of Aging

Genetic variation of MT-ND genes in frontotemporal lobar degeneration: Biochemical phenotype-genotype correlation

Gaspar, R.; Santana, I.; Mendes, C.; Fernandes, A.S.; Duro, D.; Simões, M.; Luís, D.; Santos, M.J.; Grazina, M., Neurodegenerative Diseases. 70 - 80. 2. 15. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928938610&partnerID=MN8TOARS . 10.1159/000380766 . Neurodegenerative Diseases

Scaling cognitive domains of the Montreal Cognitive Assessment: An analysis using the Partial Credit Model

Freitas, S.; Prieto, G.; Simões, M.R.; Santana, I., Archives of Clinical Neuropsychology. 435 - 447. 5. 30. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84943645294&partnerID=MN8TOARS . 10.1093/arclin/acv027 . Archives of Clinical Neuropsychology

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

Mota, S.I.; Costa, R.O.; Ferreira, I.L.; Santana, I.; Caldeira, G.L.; Padovano, C.; Fonseca, A.C.; et al, Biochimica et Biophysica Acta - Molecular Basis of Disease. 1428 - 1441. 7. 1852. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928128412&partnerID=MN8TOARS . 10.1016/j.bbadis.2015.03.015 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Severe post-influenza (H1N1) encephalitis involving pulvinar nuclei in an adult patient

Tomás, J.; Macário, M.C.; Gaspar, E.; Santana, I., BMJ Case Reports. 2015. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84951838741&partnerID=MN8TOARS . 10.1136/bcr-2015-212667 . BMJ Case Reports

Selective reminding and free and cued selective reminding in mild cognitive impairment and alzheimer disease

Lemos, R.; Afonso, A.; Martins, C.; Waters, J.H.; Blanco, F.S.; Simões, M.R.; Santana, I., Applied Neuropsychology:Adult. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941686789&partnerID=MN8TOARS . 10.1080/23279095.2015.1012761 . Applied Neuropsychology:Adult

The free and cued selective reminding test: Validation for mild cognitive impairment and Alzheimer's disease

Lemos, R.; Simões, M.R.; Santiago, B.; Santana, I., Journal of Neuropsychology. 242 - 257. 2. 9. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941192522&partnerID=MN8TOARS . 10.1111/jnp.12048 . Journal of Neuropsychology

Biparietal variant of alzheimer's disease: A rare presentation of a common disease

Marques, I.B.; Tábuas-Pereira, M.; Milheiro, M.; Santana, I., BMJ Case Reports. 2015. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921631412&partnerID=MN8TOARS . 10.1136/bcr-2014-207011 . BMJ Case Reports

Rare Variants in PLD3 Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort

Cacace, R.; Van den Bossche, T.; Engelborghs, S.; Geerts, N.; Laureys, A.; Dillen, L.; Graff, C.; et al, Human Mutation. 1226 - 1235. 12. 36. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946555494&partnerID=MN8TOARS . 10.1002/humu.22908 . Human Mutation

Cerebrospinal fluid Aß40 is similarly reduced in patients with Frontotemporal Lobar Degeneration and Alzheimer's Disease

Baldeiras, I.; Santana, I.; Leitão, M.J.; Ribeiro, M.H.; Pascoal, R.; Duro, D.; Lemos, R.; et al, Journal of the Neurological Sciences. 308 - 316. 1-2. 358. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956762726&partnerID=MN8TOARS . 10.1016/j.jns.2015.09.022 . Journal of the Neurological Sciences

Characterization of an FTLD-PDB family with the coexistence of SQSTM1 mutation and hexanucleotide (G4C2) repeat expansion in C9orf72 gene.

Almeida MR; Letra L; Pires P; Santos A; Rebelo O; Guerreiro R; van der Zee J; Van Broeckhoven C; Santana I, 2015. http://europepmc.org/abstract/med/26839080 . 10.1016/j.neurobiolaging.2015.12.015 .

The Relevance of Sociodemographic and Health Variables on MMSE Normative Data

Freitas, S.; Simões, M.R.; Alves, L.; Santana, I., Applied Neuropsychology:Adult. 311 - 319. 4. 22. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84934437185&partnerID=MN8TOARS . 10.1080/23279095.2014.926455 . Applied Neuropsychology:Adult

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

Jansen WJ; Ossenkoppele R; Knol DL; Tijms BM; Scheltens P; Verhey FR; Visser PJ; et al, 2015. http://europepmc.org/abstract/med/25988462 . 10.1001/jama.2015.4668 .

The free and cued selective reminding test for predicting progression to Alzheimer's disease in patients with mild cognitive impairment: A prospective longitudinal study.

Lemos R; Marôco J; Simões MR; Santiago B; Tomás J; Santana I, 2015. http://europepmc.org/abstract/med/26058529 .

Selective reminding and free and cued selective reminding in mild cognitive impairment and alzheimer disease.

Lemos R; Afonso A; Martins C; Waters JH; Blanco FS; Simões MR; Santana I, 2015. http://europepmc.org/abstract/med/26375308 .

Montreal cognitive assessment (MoCA): Cutoff points for mild cognitive impairment, Alzheimer's disease, frontotemporal dementia and vascular dementia | Montreal cognitive assessment (MoCA): Pontos de corte no défice cognitivo ligeiro, doença de alzheimer, demência frontotemporal e demência vascular

Freitas, S.; Simões, M.R.; Santana, I., Sinapse. 18 - 30. 1. 14. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900445658&partnerID=MN8TOARS . Sinapse

Pharmacological treatment of Alzheimer's Disease: Results and expectations after two decades of investigation and treatment | Tratamento farmacológico da Doença de Alzheimer: Resultados e expectativas de duas décadas de investigação e tratamento

Santana, I.; Santiago, B.; Cunha, L., Sinapse. 9 - 20. 1 SUPPL. 1. 14. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900434426&partnerID=MN8TOARS . Sinapse

Progranulin peripheral levels as a screening tool for the identification of subjects with progranulin mutations in a portuguese cohort

Almeida, M.R.; Baldeiras, I.; Ribeiro, M.H.; Santiago, B.; Machado, C.; Massano, J.; Guimarães, J.; Oliveira, C.R.; Santana, I., Neurodegenerative Diseases. 214 - 223. 4. 13. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893838273&partnerID=MN8TOARS . 10.1159/000352022 . Neurodegenerative Diseases

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

Van Der Zee, J.; Van Langenhove, T.; Kovacs, G.G.; Dillen, L.; Deschamps, W.; Engelborghs, S.; Matej, R.; et al, Acta Neuropathologica. 397 - 410. 3. 128. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906313820&partnerID=MN8TOARS . 10.1007/s00401-014-1298-7 . Acta Neuropathologica

Psychometric properties of the montreal cognitive assessment (MoCA): An analysis using the Rasch Model

Freitas, S.; Prieto, G.; Simões, M.R.; Santana, I., Clinical Neuropsychologist. 65 - 83. 1. 28. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893919349&partnerID=MN8TOARS . 10.1080/13854046.2013.870231 . Clinical Neuropsychologist

The free and cued selective reminding test distinguishes frontotemporal dementia from Alzheimer's disease

Lemos, R.; Duro, D.; Simões, M.R.; Santana, I., Archives of Clinical Neuropsychology. 670 - 679. 7. 29. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84911385641&partnerID=MN8TOARS . 10.1093/arclin/acu031 . Archives of Clinical Neuropsychology

Frontotemporal dementia: Neuroanatomical correlates of an atypical presentation

Felix-Morais, R.; Letra, L.; Duro, D.; Santana, I., BMJ Case Reports. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904893226&partnerID=MN8TOARS . 10.1136/bcr-2014-205089 . BMJ Case Reports

Obesity as a risk factor for Alzheimer's disease: the role of adipocytokines

Letra, L.; Santana, I.; Seiça, R., Metabolic brain disease. 563 - 568. 3. 29. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944152641&partnerID=MN8TOARS . 10.1007/s11011-014-9501-z . Metabolic brain disease

The clock drawing test: Portuguese norms, by age and education, for three different scoring systems

Santana, I.; Duro, D.; Freitas, S.; Alves, L.; Simões, M.R., Archives of Clinical Neuropsychology. 375 - 387. 4. 28. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879179846&partnerID=MN8TOARS . 10.1093/arclin/act016 . Archives of Clinical Neuropsychology

Do MCI patients with vitamin B12 deficiency have distinctive cognitive deficits?

Silva, D.; Albers, U.; Santana, I.; Vicente, M.; Martins, I.P.; Verdelho, A.; Guerreiro, M.; De-Mendonça, A., BMC Research Notes. 1. 6. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883519459&partnerID=MN8TOARS . 10.1186/1756-0500-6-357 . BMC Research Notes

Impaired processing of 3D motion-defined faces in mild cognitive impairment and healthy aging: An fMRI study

Graewe, B.; Lemos, R.; Ferreira, C.; Santana, I.; Farivar, R.; De Weerd, P.; Castelo-Branco, M., Cerebral Cortex. 2489 - 2499. 10. 23. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887901963&partnerID=MN8TOARS . 10.1093/cercor/bhs246 . Cerebral Cortex

TeLPI performance in subjects with mild cognitive impairment and alzheimer disease: A validation study

Alves, L.; Simões, M.R.; Martins, C.; Freitas, S.; Santana, I., Alzheimer Disease and Associated Disorders. 324 - 329. 4. 27. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888133081&partnerID=MN8TOARS . 10.1097/WAD.0b013e31827bdc8c . Alzheimer Disease and Associated Disorders

TREM2 variants in Alzheimer's disease.

Guerreiro R; Wojtas A; Bras J; Carrasquillo M; Rogaeva E; Majounie E; Cruchaga C; et al, 2013. http://europepmc.org/abstract/med/23150934 . 10.1056/NEJMoa1211851 .

Prediction of long-term (5 years) conversion to dementia using neuropsychological tests in a memory clinic setting

Silva, D.; Guerreiro, M.; Santana, I.; Rodrigues, A.; Cardoso, S.; Maroco, J.; De Mendonça, A., Journal of Alzheimer's Disease. 681 - 689. 3. 34. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876368687&partnerID=MN8TOARS . 10.3233/JAD-122098 . Journal of Alzheimer's Disease

Premorbid IQ influence on screening tests' scores in healthy patients and patients with cognitive impairment

Alves, L.; Simões, M.R.; Martins, C.; Freitas, S.; Santana, I., Journal of Geriatric Psychiatry and Neurology. 117 - 126. 2. 26. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884483148&partnerID=MN8TOARS . 10.1177/0891988713484194 . Journal of Geriatric Psychiatry and Neurology

Montreal cognitive assessment: Validation study for mild cognitive impairment and alzheimer disease

Freitas, S.; Simões, M.R.; Alves, L.; Santana, I., Alzheimer Disease and Associated Disorders. 37 - 43. 1. 27. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874272210&partnerID=MN8TOARS . 10.1097/WAD.0b013e3182420bfe . Alzheimer Disease and Associated Disorders

A Pan-European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats

van der Zee, J.; Gijselinck, I.; Dillen, L.; Van Langenhove, T.; Theuns, J.; Engelborghs, S.; Philtjens, S.; et al, Human Mutation. 363 - 373. 2. 34. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873093810&partnerID=MN8TOARS . 10.1002/humu.22244 . Human Mutation

Prodromal metabolic phenotype in MCI cybrids: Implications for Alzheimer's disease

Silva, D.F.; Santana, I.; Esteves, A.R.; Baldeiras, I.; Arduino, D.M.; Oliveira, C.R.; Cardoso, S.M., Current Alzheimer Research. 180 - 190. 2. 10. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875000768&partnerID=MN8TOARS . 10.2174/1567205011310020008 . Current Alzheimer Research

Transthyretin decrease in plasma of MCI and AD patients: Investigation of mechanisms for disease modulation

Ribeiro, C.A.; Santana, I.; Oliveira, C.; Baldeiras, I.; Moreira, J.; Saraiva, M.J.; Cardoso, I., Current Alzheimer Research. 881 - 889. 8. 9. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867714724&partnerID=MN8TOARS . 10.2174/156720512803251057 . Current Alzheimer Research

Serial position effects in Alzheimer's disease, mild cognitive impairment, and normal aging: Predictive value for conversion to dementia

Cunha, C.; Guerreiro, M.; De Mendona, A.; Oliveira, P.E.; Santana, I., Journal of Clinical and Experimental Neuropsychology. 841 - 852. 8. 34. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866618686&partnerID=MN8TOARS . 10.1080/13803395.2012.689814 . Journal of Clinical and Experimental Neuropsychology

Epigenetic regulation of BACE1 in Alzheimer's disease patients and in transgenic mice

Marques, S.C.F.; Lemos, R.; Ferreiro, E.; Martins, M.; de Mendonça, A.; Santana, I.; Outeiro, T.F.; Pereira, C.M.F., Neuroscience. 256 - 266. 220. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864770859&partnerID=MN8TOARS . 10.1016/j.neuroscience.2012.06.029 . Neuroscience

Differences between early and late-onset Alzheimer's disease in neuropsychological tests

Sá, F.; Pinto, P.; Cunha, C.; Lemos, R.; Letra, L.; Simões, M.; Santana, I., Frontiers in Neurology. MAY. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865835722&partnerID=MN8TOARS . 10.3389/fneur.2012.00081 . Frontiers in Neurology

CSF biomarkers for the early diagnosis of Alzheimer's disease in a routine clinical setting - The first Portuguese study | Biomarcadores do LCR no diagnóstico precoce da doença de Alzheimer em ambiente clínico de rotina - o primeiro estudo em Portugal

Baldeiras, I.; Santana, I.; Garrucho, M.H.; Pascoal, R.; Lemos, R.; Santiago, B.; de Oliveira, C.R., Sinapse. 14 - 22. 2. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872921979&partnerID=MN8TOARS . Sinapse

Montreal cognitive assessment (MoCA): Validation study for vascular dementia

Freitas, S.; Simões, M.R.; Alves, L.; Vicente, M.; Santana, I., Journal of the International Neuropsychological Society. 1031 - 1040. 6. 18. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868377857&partnerID=MN8TOARS . 10.1017/S135561771200077X . Journal of the International Neuropsychological Society

Montreal cognitive assessment: Influence of sociodemographic and health variables

Freitas, S.; Simões, M.R.; Alves, L.; Santana, I., Archives of Clinical Neuropsychology. 165 - 175. 2. 27. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862255082&partnerID=MN8TOARS . 10.1093/arclin/acr116 . Archives of Clinical Neuropsychology

Construct validity of the Montreal Cognitive Assessment (MoCA)

Freitas, S.; Simões, M.R.; Marôco, J.; Alves, L.; Santana, I., Journal of the International Neuropsychological Society. 242 - 250. 2. 18. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857757347&partnerID=MN8TOARS . 10.1017/S1355617711001573 . Journal of the International Neuropsychological Society

Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer's disease

Guerreiro, R.J.; Lohmann, E.; Kinsella, E.; Brás, J.M.; Luu, N.; Gurunlian, N.; Dursun, B.; et al, Neurobiology of Aging. 5. 33. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858335381&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2011.10.009 . Neurobiology of Aging

The clock drawing test: Influence of sociodemographic and health variables in the portuguese population | O teste do desenho do relógio: Influência das variáveis sóciodemográficas e de saúde na população portuguesa

Duro, D.; Freitas, S.; Alves, L.; Simões, M.R.; Santana, I., Sinapse. 5 - 12. 1. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863808623&partnerID=MN8TOARS . Sinapse

Amyloid ß-induced ER stress is enhanced under mitochondrial dysfunction conditions

Costa, R.O.; Ferreiro, E.; Martins, I.; Santana, I.; Cardoso, S.M.; Oliveira, C.R.; Pereira, C.M.F., Neurobiology of Aging. 4. 33. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856951448&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2011.04.011 . Neurobiology of Aging

Montreal Cognitive Assessment (MoCA): Validation study for frontotemporal dementia

Freitas, S.; Simões, M.R.; Alves, L.; Duro, D.; Santana, I., Journal of Geriatric Psychiatry and Neurology. 146 - 154. 3. 25. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868372524&partnerID=MN8TOARS . 10.1177/0891988712455235 . Journal of Geriatric Psychiatry and Neurology

Multiple dural arteriovenous fistulas presenting as rapidly progressive dementia

Mendonça, N.; Santos, G.; Duro, D.; MacHado, E.; Goulão, A.; Santana, I., Neurologist. 130 - 132. 3. 18. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861145878&partnerID=MN8TOARS . 10.1097/NRL.0b013e318251e695 . Neurologist

Temporal integration of 3D coherent motion cues defining visual objects of unknown orientation is impaired in amnestic mild cognitive impairment and Alzheimer's disease

Lemos, R.; Figueiredo, P.; Santana, I.; Simões, M.R.; Castelo-Branco, M., Journal of Alzheimer's Disease. 885 - 896. 4. 28. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858018563&partnerID=MN8TOARS . 10.3233/JAD-2011-110719 . Journal of Alzheimer's Disease

P2-277: The clock drawing test: Normative data for the Portuguese population

Santana, Isabel; Duro, Diana; Alves, Lara; Freitas, Sandra; Simões, Mário, Alzheimer's & Dementia. P359 - P360. 4S_Part_10. 8. 2012. http://dx.doi.org/10.1016/j.jalz.2012.05.985 . 10.1016/j.jalz.2012.05.985 . Alzheimer's & Dementia

Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer's disease.

Guerreiro, R.J.; Lohmann, E.; Kinsella, E.; Brás, J.M.; Luu, N.; Gurunlian, N.; Dursun, B.; et al, Neurobiology of aging. 5. 33. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866136235&partnerID=MN8TOARS . Neurobiology of aging

P2-009: The chemokines IL8 and MIP-1b distinguish mild cognitive impairment from early stage Alzheimer's disease

Gonçalves, Milene; Santana, Isabel; Francisco, Natália; Cunha, Catarina; Batista, Sonia; Kodandaraman, Geema; Souto-Carneiro, Margarida, Alzheimer's & Dementia. P266 - P267. 4S_Part_7. 8. 2012. http://dx.doi.org/10.1016/j.jalz.2012.05.712 . 10.1016/j.jalz.2012.05.712 . published Alzheimer's & Dementia

Comparison of four verbal memory tests for the diagnosis and predictive value of mild cognitive impairment.

Silva D; Guerreiro M; Maroco J; Santana I; Rodrigues A; Bravo Marques J; de Mendonça A, 2012. http://europepmc.org/abstract/med/22590473 . 10.1159/000336224 .

Differences between Early and Late-Onset Alzheimer's Disease in Neuropsychological Tests.

Sá F; Pinto P; Cunha C; Lemos R; Letra L; Simões M; Santana I, 2012. http://europepmc.org/abstract/med/22593755 .

P2-019: Memory decline and cerebrospinal fluid biomarkers in MCI

Baldeiras, Ines; Lemos, Raquel; Cunha, Catarina; Ribeiro, Maria Helena; Santiago, Beatriz; Oliveira, Catarina; Santana, Isabel, Alzheimer's & Dementia. S313 - S313. 7. 2011. http://dx.doi.org/10.1016/j.jalz.2011.05.909 . 10.1016/j.jalz.2011.05.909 . published Alzheimer's & Dementia

P1-470: Validity study of the Montreal cognitive assessment in patients with vascular dementia

Santana, Isabel; Freitas, Sandra; Simões, Mário Rodrigues, Alzheimer's & Dementia. S264 - S264. 7. 2011. http://dx.doi.org/10.1016/j.jalz.2011.05.752 . 10.1016/j.jalz.2011.05.752 . published Alzheimer's & Dementia

Data mining methods in the prediction of Dementia: A real-data comparison of the accuracy, sensitivity and specificity of linear discriminant analysis, logistic regression, neural networks, support vector machines, classification trees and random forests

Maroco, J.; Silva, D.; Rodrigues, A.; Guerreiro, M.; Santana, I.; De Mendonça, A., BMC Research Notes. 4. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051660823&partnerID=MN8TOARS . 10.1186/1756-0500-4-299 . BMC Research Notes

P1-435: Free and cued selective reminding in mild cognitive impairment and Alzheimer's disease

Lemos, Raquel; Afonso, Ana; Martins, Cristina; Simões, Mário; Santana, Isabel, Alzheimer's & Dementia. S252 - S252. 7. 2011. http://dx.doi.org/10.1016/j.jalz.2011.05.717 . 10.1016/j.jalz.2011.05.717 . Alzheimer's & Dementia

P1-476: Comparison of two verbal memory tests for the diagnosis and predictive value of MCI

Silva, Dina; de Mendonça, Alexandre; Santana, Isabel; Rodrigues, Ana; Maroco, João; Guerreiro, Manuela, Alzheimer's & Dementia. S266 - S266. 7. 2011. http://dx.doi.org/10.1016/j.jalz.2011.05.759 . 10.1016/j.jalz.2011.05.759 . published Alzheimer's & Dementia

Montreal Cognitive Assessment (MoCA): Normative study for the Portuguese population

Freitas, S.; Simões, M.R.; Alves, L.; Santana, I., Journal of Clinical and Experimental Neuropsychology. 989 - 996. 9. 33. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855657605&partnerID=MN8TOARS . 10.1080/13803395.2011.589374 . Journal of Clinical and Experimental Neuropsychology

The Portuguese who could no longer speak French: Primary progressive aphasia in a bilingual man

Machado, Á.; Rodrigues, M.; Simões, S.; Santana, I.; Soares-Fernandes, J., Journal of Neuropsychiatry and Clinical Neurosciences. 1. 22. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-76749161467&partnerID=MN8TOARS . Journal of Neuropsychiatry and Clinical Neurosciences

Oxidative damage and progression to Alzheimer's disease in patients with mild cognitive impairment.

Baldeiras I; Santana I; Proença MT; Garrucho MH; Pascoal R; Rodrigues A; Duro D; Oliveira CR, 2010. http://europepmc.org/abstract/med/21504121 .

Oxidative damage and progression to Alzheimer's disease in patients with mild cognitive impairment

Baldeiras, I.; Santana, I.; Proença, M.T.; Garrucho, M.H.; Pascoal, R.; Rodrigues, A.; Duro, D.; Oliveira, C.R., Journal of Alzheimer's Disease. 1165 - 1177. 4. 21. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650467580&partnerID=MN8TOARS . 10.3233/JAD-2010-091723 . Journal of Alzheimer's Disease

Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP

Guerreiro, R.J.; Baquero, M.; Blesa, R.; Boada, M.; Brás, J.M.; Bullido, M.J.; Calado, A.; et al, Neurobiology of Aging. 725 - 731. 5. 31. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950529014&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2008.06.012 . Neurobiology of Aging

Validation studies of the Portuguese experimental version of the Montreal Cognitive Assessment (MoCA): Confirmatory factor analysis

Duro, D.; Simões, M.R.; Ponciano, E.; Santana, I., Journal of Neurology. 728 - 734. 5. 257. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954457477&partnerID=MN8TOARS . 10.1007/s00415-009-5399-5 . Journal of Neurology

The Portuguese who could no longer speak French: primary progressive aphasia in a bilingual man.

Machado A; Rodrigues M; Simões S; Santana I; Soares-Fernandes J, 2010. http://europepmc.org/abstract/med/20160239 . 10.1176/appi.neuropsych.22.1.123-s.e31 .

Genetic variability in CLU and its association with Alzheimer's disease

Guerreiro, R.J.; Beck, J.; Gibbs, J.R.; Santana, I.; Rossor, M.N.; Schott, J.M.; Nalls, M.A.; et al, PLoS ONE. 3. 5. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949784437&partnerID=MN8TOARS . 10.1371/journal.pone.0009510 . PLoS ONE

Primary bilateral thalamic astrocytoma presenting with head tremor, ataxia, and dementia

Machado, Á.; Ribeiro, M.; Rodrigues, M.; Ferreira, C.; Almeida, R.; Santana, I.; Castro, L.; Carpenter, S., Journal of Neuropsychiatry and Clinical Neurosciences. 3. 22. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955455926&partnerID=MN8TOARS . Journal of Neuropsychiatry and Clinical Neurosciences

Primary bilateral thalamic astrocytoma presenting with head tremor, ataxia, and dementia.

Machado A; Ribeiro M; Rodrigues M; Ferreira C; Almeida R; Santana I; Castro L; Carpenter S, 2010. http://europepmc.org/abstract/med/20686149 . 10.1176/appi.neuropsych.22.3.352-e.e7 .

Cognitive deficits in middle-aged and older adults with bipolar disorder and cognitive complaints: Comparison with mild cognitive impairment

Silva, D.; Santana, I.; do Couto, F.S.; Maroco, J.; Guerreiro, M.; de Mendonça, A., International Journal of Geriatric Psychiatry. 624 - 631. 6. 24. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649354789&partnerID=MN8TOARS . 10.1002/gps.2166 . International Journal of Geriatric Psychiatry

Diagnostic value of CSF protein profile in a Portuguese population of sCJD patients

Baldeiras, I.E.; Ribeiro, M.H.; Pacheco, P.; MacHado, Á.; Santana, I.; Cunha, L.; Oliveira, C.R., Journal of Neurology. 1540 - 1550. 9. 256. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-69549118450&partnerID=MN8TOARS . 10.1007/s00415-009-5160-0 . Journal of Neurology

Sporadic Creutzfeldt-Jakob disease causing a 2-years slowly progressive isolated dementia

MacHado, A.; Ribeiro, M.; Rodrigues, M.; Ferreira, C.; Baldeiras, I.; Ribeiro, M.H.; Santana, I.; et al, Behavioural Neurology. 175 - 179. 3-4. 21. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-72949094841&partnerID=MN8TOARS . 10.3233/BEN-2009-0238 . Behavioural Neurology

Novel progranulin mutation: Screening for PGRN mutations in a Portuguese series of FTD/CBS cases

Guerreiro, R.J.; Santana, I.; Bras, J.M.; Revesz, T.; Rebelo, O.; Ribeiro, M.H.; Santiago, B.; et al, Movement Disorders. 1269 - 1273. 9. 23. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-51449107701&partnerID=MN8TOARS . 10.1002/mds.22078 . Movement Disorders

Peripheral oxidative damage in mild cognitive impairment and mild Alzheimer's disease

Baldeiras, I.; Santana, I.; Proença, M.T.; Garrucho, M.H.; Pascoal, R.; Rodrigues, A.; Duro, D.; Oliveira, C.R., Journal of Alzheimer's Disease. 117 - 128. 1. 15. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-52449117220&partnerID=MN8TOARS . Journal of Alzheimer's Disease

Variant Creutzfeldt-Jacob disease: The second case in Portugal and in the same geographical region

Machado, Á.; Soares, H.; Antunes, H.; Magalhães, Z.; Ferreira, C.; Baldeiras, I.; Ribeiro, M.H.; et al, Journal of Neurology, Neurosurgery and Psychiatry. 180 - 182. 2. 79. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-38849188806&partnerID=MN8TOARS . 10.1136/jnnp.2007.128389 . Journal of Neurology, Neurosurgery and Psychiatry

Dementia genetics - A brief review | Genética das demências - Uma breve revisão

Guerreiro, R.J.; Brás, J.M.; Santana, I.; Oliveira, C., Sinapse. 13 - 20. 1. 8. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-54249130812&partnerID=MN8TOARS . Sinapse

Peripheral oxidative damage in mild cognitive impairment and mild Alzheimer's disease.

Baldeiras I; Santana I; Proença MT; Garrucho MH; Pascoal R; Rodrigues A; Duro D; Oliveira CR, 2008. http://europepmc.org/abstract/med/18780972 .

Adaptive visual memory reorganization in right medial temporal lobe epilepsy

Figueiredo, P.; Santana, I.; Teixeira, J.; Cunha, C.; Machado, E.; Sales, F.; Almeida, E.; Castelo-Branco, M., Epilepsia. 1395 - 1408. 8. 49. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-48149087971&partnerID=MN8TOARS . 10.1111/j.1528-1167.2008.01629.x . Epilepsia

Peripheral inflammatory cytokines as biomarkers in Alzheimer's disease and mild cognitive impairment

Guerreiro, R.J.; Santana, I.; Brás, J.M.; Santiago, B.; Paiva, A.; Oliveira, C., Neurodegenerative Diseases. 406 - 412. 6. 4. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35048877702&partnerID=MN8TOARS . 10.1159/000107700 . Neurodegenerative Diseases

Association of HFE common mutations with Parkinson's disease, Alzheimer's disease and mild cognitive impairment in a Portuguese cohort

Guerreiro, R.J.; Bras, J.M.; Santana, I.; Januario, C.; Santiago, B.; Morgadinho, A.S.; Ribeiro, M.H.; et al, BMC Neurology. 6. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747179546&partnerID=MN8TOARS . 10.1186/1471-2377-6-24 . BMC Neurology

Genetic basis of Alzheimer's dementia: Role of mtDNA mutations

Grazina, M.; Pratas, J.; Silva, F.; Oliveira, S.; Santana, I.; Oliveira, C., Genes, Brain and Behavior. 92 - 107. SUPPL. 2. 5. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646236099&partnerID=MN8TOARS . 10.1111/j.1601-183X.2006.00225.x . Genes, Brain and Behavior

Mitochondrial DNA variants in a Portuguese population of patients with Alzheimer's disease

Grazina, M.; Silva, F.; Santana, I.; Pratas, J.; Santiago, B.; Oliveira, M.; Carreira, I.; Cunha, L.; Oliveira, C., European Neurology. 121 - 124. 3. 53. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-20844462230&partnerID=MN8TOARS . 10.1159/000085555 . European Neurology

Frontotemporal dementia and mitochondrial DNA transitions

Grazina, M.; Silva, F.; Santana, I.; Santiago, B.; Mendes, C.; Simões, M.; Oliveira, M.; Cunha, L.; Oliveira, C., Neurobiology of Disease. 306 - 311. 2. 15. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1542300730&partnerID=MN8TOARS . 10.1016/j.nbd.2003.11.004 . Neurobiology of Disease

Cytochrome c oxidase is decreased in Alzheimer's disease platelets

Cardoso, S.M.; Proença, M.T.; Santos, S.; Santana, I.; Oliveira, C.R., Neurobiology of Aging. 105 - 110. 1. 25. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-0348111546&partnerID=MN8TOARS . 10.1016/S0197-4580(03)00033-2 . Neurobiology of Aging

Mitochondria dysfunction of Alzheimer's disease cybrids enhances Aß toxicity

Cardoso, S.M.; Santana, I.; Swerdlow, R.H.; Oliveira, C.R., Journal of Neurochemistry. 1417 - 1426. 6. 89. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-3042513691&partnerID=MN8TOARS . 10.1111/j.1471-4159.2004.02438.x . Journal of Neurochemistry

[Cognitive effects of therapy with topiramate in patients with refractory partial epilepsy].

Baeta E; Santana I; Castro G; Gonçalves S; Gonçalves T; Carmo I; Caritas AI, 2002. http://europepmc.org/abstract/med/12080493 .

Cognitive effects of therapy with topiramate in patients with refractory partial epilepsy | Efectos cognitivos del tratamiento con topiramato en pacientes con epilepsia parcial refractaria

Baeta, E.; Santana, I.; Castro, G.; Gonçalves, S.; Gonçalves, T.; Carmo, I.; Caritas, A.I., Revista de Neurologia. 737 - 741. 8. 34. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037117438&partnerID=MN8TOARS . Revista de Neurologia

Malformations of cortical development in patients with epilepsy: Neuroimaging study of 17 patients | Malformações do desenvolvimento cortical em doentes com epilepsia: Estudo neuroimagiológico de 17 casos

Carvalho, S.; Brito, O.; Machado, E.; Santos, N.; Freitas, P.M.; Bento, C.; Santana, I.; Sales, F.; Martins, F., Acta Medica Portuguesa. 103 - 106. 1. 14. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346405516&partnerID=MN8TOARS . Acta Medica Portuguesa

[Malformations in cortical development in patients with epilepsy. Neuroimaging of 17 cases]

Carvalho S; Brito O; Machado E; Santos N; Freitas PM; Bento C; Santana I; Sales F; Martins F, 2001. http://europepmc.org/abstract/med/11321963 .

Apolipoprotein E e4 allele is a risk factor for Alzheimer's disease: The central region of Portugal (Coimbra) as a case study

Fernandes, M.A.S.; Oliveira, C.R.; Oliveira, L.M.V.; Nogueira, A.J.A.; Santiago, B.; Santana, I., European Neurology. 183 - 184. 3. 42. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032589726&partnerID=MN8TOARS . 10.1159/000008098 . European Neurology

Effects of apolipoprotein E genotype on blood lipid composition and membrane platelet fluidity in Alzheimer's disease

Fernandes, M.A.S.; Proença, M.T.; Nogueira, A.J.A.; Oliveira, L.M.V.; Santiago, B.; Santana, I.; Oliveira, C.R., Biochimica et Biophysica Acta - Molecular Basis of Disease. 89 - 96. 1. 1454. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032937469&partnerID=MN8TOARS . 10.1016/S0925-4439(99)00030-7 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Influence of apolipoprotein E genotype on blood redox status of Alzheimer's disease patients.

Fernandes, M.A.; Proenca, M.T.; Nogueira, A.J.; Grazina, M.M.; Oliveira, L.M.; Fernandes, A.I.; Santiago, B.; Santana, I.; Oliveira, C.R., International journal of molecular medicine. 179 - 186. 2. 4. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033175761&partnerID=MN8TOARS . International journal of molecular medicine

Apolipoprotein E genotype has no effect on the free intracellular Ca2+ concentration of platelets from Alzheimer's disease patients.

Fernandes MA; Proença MT; Nogueira AJ; Oliveira LM; Santiago B; Santana I; Oliveira CR, 1999. http://europepmc.org/abstract/med/10085419 .

Influence of apolipoprotein E genotype on blood redox status of Alzheimer's disease patients.

Fernandes MA; Proenca MT; Nogueira AJ; Grazina MM; Oliveira LM; Fernandes AI; Santiago B; Santana I; Oliveira CR, 1999. http://europepmc.org/abstract/med/10402486 .

Apolipoprotein e genotype has no effect on the free intracellular Ca 2+ concentration of platelets from Alzheimer's disease patients

Fernandes, M.A.S.; Proenca, M.T.; Nogueira, A.J.A.; Oliveira, L.M.V.; Santiago, B.; Santana, I.; Oliveira, C.R., International Journal of Molecular Medicine. 431 - 434. 4. 3. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033109294&partnerID=MN8TOARS . International Journal of Molecular Medicine

Studies of the aluminium effect on superoxide dismutase activity of healthy human erythrocytes and osmotic fragility of erythrocytes in Alzheimer's disease

Fernandes, M.A.S.; Santana, I.; Oliveira, C.R., Alzheimer's Research. 73 - 78. 3. 2. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030037891&partnerID=MN8TOARS . Alzheimer's Research

[Frontal lobe-type dementia associated with motor neuron disease]

Santana I; Macario MC; Rebelo O; Pires MM, 1995. http://europepmc.org/abstract/med/8713508 .

Frontal lobe-type dementia associated with motor neuron disease | Demencia do tipo frontal associada a doenca do neuronio motor.

Santana, I.; Macario, M.C.; Rebelo, O.; Pires, M.M., Acta médica portuguesa. 629 - 634. 11. 8. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029399649&partnerID=MN8TOARS . Acta médica portuguesa

Decreased superoxide dismutase activity in erythrocytes from patients with Alzheimer's disease

Fernandes, M.A.S.; Santana, I.; Januario, C.; Cunha, L.; Oliveira, C.R., Medical Science Research. 679 - 682. 18. 21. 1993. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027366364&partnerID=MN8TOARS . Medical Science Research