Magda Matos Santana

A standardised protocol for blood and cerebrospinal fluid collection and processing for biomarker research in ataxia

Santana, Magda M.; Gaspar, Laetitia S.; Pinto, Maria M.; Silva, Patrick; Adão, Diana; Pereira, Dina; Ribeiro, Joana Afonso; et al, Neuropathology and Applied Neurobiology. 2. 49. 2023. http://dx.doi.org/10.1111/nan.12892 . 10.1111/nan.12892 . Neuropathology and Applied Neurobiology

SCAview: an Intuitive Visual Approach to the Integrative Analysis of Clinical Data in Spinocerebellar Ataxias

Uebachs, Mischa; Wegner, Philipp; Schaaf, Sebastian; Kugai, Simon; Jacobi, Heike; Kuo, Sheng-Han; Ashizawa, Tetsuo; et al, The Cerebellum. 2023. http://dx.doi.org/10.1007/s12311-023-01546-0 . 10.1007/s12311-023-01546-0 . The Cerebellum

Extracellular communication between brain cells through functional transfer of Cre mRNA

David Rufino-Ramos; Kevin Leandro; Pedro R.L. Perdigão; Killian O’Brien; Maria Manuel Pinto; Magda M. Santana; Thomas S van Solinge; et al, 2023. https://doi.org/10.1101/2023.01.29.525937 . 10.1101/2023.01.29.525937 .

The frequency of non-motor symptoms in SCA3 and their association with disease severity and lifestyle factors

Hengel, Holger; Martus, Peter; Faber, Jennifer; Giunit, Paola; Garcia-Moreno, Hector; Solanky, Nita; Klockgether, Thomas; et al, Journal of Neurology. 944 - 952. 2. 270. 2022. http://dx.doi.org/10.1007/s00415-022-11441-z . 10.1007/s00415-022-11441-z . Journal of Neurology

Establishment and characterization of human pluripotent stem cells-derived brain organoids to model cerebellar diseases

Brás, João; Henriques, Daniel; Moreira, Ricardo; Santana, Magda M.; Silva-Pedrosa, Rita; Adão, Diana; Braz, Sandra; et al, Scientific Reports. 1. 12. 2022. http://dx.doi.org/10.1038/s41598-022-16369-y . 10.1038/s41598-022-16369-y . Scientific Reports

Tau and neurofilament light-chain as fluid biomarkers in spinocerebellar ataxia type 3

Hector Garcia-Moreno; Mercedes Prudencio; Gilbert Thomas-Black; Nita Solanky; Karen R. Jansen-West; Rana Hanna AL-Shaikh; Amanda Heslegrave; et al, European Journal of Neurology. 2022. https://doi.org/10.1111/ene.15373 . 10.1111/ene.15373 . European Journal of Neurology

Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph Disease

Miranda, Catarina Oliveira; Nobre, Rui Jorge; Paiva, Vitor Hugo; Duarte, João Valente; Castelhano, João; Petrella, Lorena Itatí; Sereno, José; et al, Acta Neuropathologica Communications. 1. 10. 2022. http://dx.doi.org/10.1186/s40478-022-01329-4 . 10.1186/s40478-022-01329-4 . Acta Neuropathologica Communications

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Santana, Magda M, Autophagy. 2021. https://pubmed.ncbi.nlm.nih.gov/33634751/ . published Autophagy

Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood

Hübener-Schmid, Jeannette; Kuhlbrodt, Kirsten; Peladan, Julien; Faber, Jennifer; Santana, Magda M.; Hengel, Holger; Jacobi, Heike; et al, Movement Disorders. 2675 - 2681. 11. 36. 2021. http://dx.doi.org/10.1002/mds.28749 . 10.1002/mds.28749 . Movement Disorders

Characterization of Lifestyle in Spinocerebellar Ataxia Type 3 and Association with Disease Severity

Hengel, Holger; Martus, Peter; Faber, Jennifer; Garcia-Moreno, Hector; Solanky, Nita; Giunti, Paola; Klockgether, Thomas; et al, Movement Disorders. 405 - 410. 2. 37. 2021. http://dx.doi.org/10.1002/mds.28844 . 10.1002/mds.28844 . Movement Disorders

Simple and Fast Size Exclusion Chromatography-based Protocol to Isolate Human Plasma-derived Extracellular Vesicles for Transcriptional Research

Gaspar, Laetitia S.; Santana, Magda M.; Henriques, Carina; Pinto, Maria M.; Ribeiro-Rodrigues, Teresa M.; Girão, Henrique; Nobre, Rui Jorge; Pereira de Almeida, Luís, Molecular Therapy - Methods & Clinical Development. 2020. http://dx.doi.org/10.1016/j.omtm.2020.07.012 . 10.1016/j.omtm.2020.07.012 . Molecular Therapy - Methods & Clinical Development

Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and mice

Wilke, Carlo; Haas, Eva; Reetz, Kathrin; Faber, Jennifer; Garcia-Moreno, Hector; Santana, Magda M; Warrenburg, Bart; et al, EMBO Molecular Medicine. 7. 12. 2020. http://dx.doi.org/10.15252/emmm.201911803 . 10.15252/emmm.201911803 . EMBO Molecular Medicine

Trehalose alleviates the phenotype of Machado-Joseph disease mouse models

Santana, Magda M.; Paixão, Susana; Cunha-Santos, Janete; Silva, Teresa Pereira; Trevino-Garcia, Allyson; Gaspar, Laetitia S.; Nóbrega, Clévio; et al, Journal of Translational Medicine. 1. 18. 2020. http://dx.doi.org/10.1186/s12967-020-02302-2 . 10.1186/s12967-020-02302-2 . Journal of Translational Medicine

Neuropeptide Y stimulates autophagy in hypothalamic neurons.

Aveleira CA; Botelho M; Carmo-Silva S; Pascoal JF; Ferreira-Marques M; Nóbrega C; Cortes L; et al, 2015. http://europepmc.org/abstract/med/25775546 . 10.1073/pnas.1416609112 .

Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress.

Kaster MP; Machado NJ; Silva HB; Nunes A; Ardais AP; Santana M; Baqi Y; et al, 2015. http://europepmc.org/abstract/med/26056314 . 10.1073/pnas.1423088112 .

Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress

Santana, Magda M.; Rosmaninho-Salgado, Joana; Cortez, Vera; Pereira, Frederico C.; Kaster, Manuella P.; Aveleira, Célia A.; Ferreira, Marisa; et al, European Neuropsychopharmacology. 1753 - 1766. 10. 25. 2015. http://dx.doi.org/10.1016/j.euroneuro.2015.06.013 . 10.1016/j.euroneuro.2015.06.013 . published European Neuropsychopharmacology

Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress

Faria, R.; Santana, M.M.; Aveleira, C.A.; Simões, C.; Maciel, E.; Melo, T.; Santinha, D.; et al, Neuroscience. 1 - 11. 273. 2014. http://dx.doi.org/10.1016/j.neuroscience.2014.04.042 . 10.1016/j.neuroscience.2014.04.042 . published Neuroscience

Progenitor cells in chromospheres: in response to Arthur S. Tischler.

Santana MM; Ehrhart-Bornstein M; Cavadas C, 2013. http://europepmc.org/abstract/med/24282325 . 10.5966/sctm.2013-0062 .

Isolation, characterization, and differentiation of progenitor cells from human adult adrenal medulla.

Santana MM; Chung KF; Vukicevic V; Rosmaninho-Salgado J; Kanczkowski W; Cortez V; Hackmann K; et al, 2012. http://europepmc.org/abstract/med/23197690 . 10.5966/sctm.2012-0022 .

Regulation of catecholamine release in human adrenal chromaffin cells by ß-adrenoceptors

Cortez, Vera; Santana, Magda; Marques, Ana Patrícia; Mota, Alfredo; Rosmaninho-Salgado, Joana; Cavadas, Cláudia, Neurochemistry International. 387 - 393. 4. 60. 2012. http://dx.doi.org/10.1016/j.neuint.2011.12.018 . 10.1016/j.neuint.2011.12.018 . published Neurochemistry International

Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-¿ expression

Rosmaninho-Salgado, Joana; Marques, Ana Patricia; Estrada, Marta; Santana, Magda; Cortez, Vera; Grouzmann, Eric; Cavadas, Cláudia, Peptides. 49 - 54. 1. 37. 2012. http://dx.doi.org/10.1016/j.peptides.2012.06.014 . 10.1016/j.peptides.2012.06.014 . published Peptides

Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes

Rosmaninho-Salgado, Joana; Cortez, Vera; Estrada, Marta; Santana, Magda M.; Gonçalves, Alexandra; Marques, Ana Patrícia; Cavadas, Cláudia, Neuropeptides. 359 - 366. 6. 46. 2012. http://dx.doi.org/10.1016/j.npep.2012.08.006 . 10.1016/j.npep.2012.08.006 . published Neuropeptides

Proliferative Hypothalamic Neurospheres Express NPY, AGRP, POMC, CART and Orexin-A and Differentiate to Functional Neurons

Sousa-Ferreira, Lígia; Álvaro, Ana Rita; Aveleira, Célia; Santana, Magda; Brandão, Inês; Kügler, Sebastian; Pereira de Almeida, Luís; Cavadas, Cláudia, PLoS ONE. 5. 6. 2011. http://dx.doi.org/10.1371/journal.pone.0019745 . 10.1371/journal.pone.0019745 . published PLoS ONE