Publications

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Information about journal articles, updated at 19-01-2025, from platform CIÊNCIAVITAE.

Oxidized cholesteryl ester induces exocytosis of dysfunctional lysosomes in lipidotic macrophages

Neuza Domingues; André R. A. Marques; Rita Diogo Almeida Calado; Inês Ferreira; Cristiano Ramos; José Ramalho; Maria I. L. Soares; et al, Traffic. 2023. http://dx.doi.org/10.1111/tra.12888 . 10.1111/tra.12888 . Traffic

Cx43-mediated hyphal folding counteracts phagosome integrity loss during fungal infection

Beatriz Cristovao; Lisa Rodrigues; Steve Catarino; Monica Abreu; Teresa Gonçalves; Domingues, Neuza; Girao H, Microbiology Spectrum. 2023. http://dx.doi.org/10.1128/spectrum.01238-23 . 10.1128/spectrum.01238-23 . Microbiology Spectrum

Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation

Neuza Domingues; Joana Gaifem; Rune Matthiesen; Diana P. Saraiva; Luís Bento; André R.A. Marques; Maria I.L. Soares; et al, Journal of Lipid Research. 2023. https://doi.org/10.1016/j.jlr.2023.100419 . 10.1016/j.jlr.2023.100419 . Journal of Lipid Research

Phagolysosomal remodeling to confine C. albicans in macrophage

Domingues, Neuza; Gonçalves, Teresa; Girao, Henrique, Trends in microbiology. 2022. accepted Trends in microbiology

1,8-cineole Ameliorates Right Ventricle Dysfunction Associated With Pulmonary Arterial Hypertension by Restoring Connexin 43 and Mitochondrial Homeostasis

Pharmacological Research. 106151 - 106151. 2022. http://dx.doi.org/10.1016/j.phrs.2022.106151 . 10.1016/j.phrs.2022.106151 . Pharmacological Research

Insulin resistance as a predictor of cardiovascular diseases

Revista Portuguesa de Cardiologia. 545 - 546. 8. 40. 2021. http://dx.doi.org/10.1016/j.repc.2021.06.004 . 10.1016/j.repc.2021.06.004 . Revista Portuguesa de Cardiologia

Shotgun mass spectrometry-based lipid profiling identifies and distinguishes between chronic inflammatory diseases

EBioMedicine. 103504 - 103504. 70. 2021. http://dx.doi.org/10.1016/j.ebiom.2021.103504 . 10.1016/j.ebiom.2021.103504 . EBioMedicine

Cholesteryl Hemiazelate Induces Lysosome Dysfunction and Exocytosis in Macrophages

Domingues, Neuza; Rita Diogo Almeida Calado; Patrícia H. Brito; Rune Matthiesen; José Ramalho; Maria I. L. Soares; Telmo Pereira; et al, Arteriosclerosis, Thrombosis and Vascular Biology. 2020. under revision Arteriosclerosis, Thrombosis and Vascular Biology

Molecular crowding effects on the distribution of amphiphiles in biological media

Martins, Patrícia A.T.; Domingues, Neuza; Pires, Cristiana; Alves, Ana Maria; Palmeira, Tiago; Samelo, Jaime; Cardoso, Renato; Velazquez-Campoy, Adrian; Moreno, Maria João, Colloids and Surfaces B: Biointerfaces. 319 - 325. 180. 2019. http://dx.doi.org/10.1016/j.colsurfb.2019.04.065 . 10.1016/j.colsurfb.2019.04.065 . Colloids and Surfaces B: Biointerfaces

Lipid and Non-lipid Factors Affecting Macrophage Dysfunction and Inflammation in Atherosclerosis

Gibson, Mark S.; Domingues, Neuza; Vieira, Otilia V., Frontiers in Physiology. 9. 2018. http://dx.doi.org/10.3389/fphys.2018.00654 . 10.3389/fphys.2018.00654 . Frontiers in Physiology

Cholesterol is Inefficiently Converted to Cholesteryl Esters in the Blood of Cardiovascular Disease Patients

Domingues, Neuza, Scientific Reports. 2018. http://dx.doi.org/10.1038/s41598-018-33116-4 . 10.1038/s41598-018-33116-4 . Scientific Reports

Involvement of the p62/NRF2 signal transduction pathway on erythrophagocytosis

Santarino, I.B.; Viegas, M.S.; Domingues, N.S.; Ribeiro, A.M.; Soares, M.P.; Vieira, O.V., Scientific Reports. 1. 7. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85025474729&partnerID=MN8TOARS . 10.1038/s41598-017-05687-1 . Scientific Reports

Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages

Domingues, Neuza; Estronca, Luís M.B.B.; Silva, João; Encarnação, Marisa R.; Mateus, Rita; Silva, Diogo; Santarino, Inês B.; et al, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 210 - 220. 2. 1862. 2017. http://dx.doi.org/10.1016/j.bbalip.2016.10.009 . 10.1016/j.bbalip.2016.10.009 . Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

In vitro effects of bis(1,2-dimethyl-3-hydroxy-4-pyridinonato)oxidovanadium(IV), or VO(dmpp)2, on insulin secretion in pancreatic islets of type 2 diabetic Goto-Kakizaki rats

Pelletier, Julien; Domingues, Neuza; Castro, M.Margarida C.A.; Östenson, Claes-Göran, Journal of Inorganic Biochemistry. 29 - 34. 154. 2016. http://dx.doi.org/10.1016/j.jinorgbio.2015.11.004 . 10.1016/j.jinorgbio.2015.11.004 . Journal of Inorganic Biochemistry

Quaternary ammonium surfactant structure determines selective toxicity towards bacteria: mechanisms of action and clinical implications in antibacterial prophylaxis

Inácio, Ângela S.; Domingues, Neuza S.; Nunes, Alexandra; Martins, Patrícia T.; Moreno, Maria J.; Estronca, Luís M.; Fernandes, Rui; et al, 2016. http://hdl.handle.net/10400.18/3438 . 10.1093/jac/dkv405 .

Therapeutic properties of VO(dmpp)2 as assessed by in vitro and in vivo studies in type 2 diabetic GK rats

Domingues, N.; Pelletier, J.; Ostenson, C.-G.; Castro, M.M.C.A., Journal of Inorganic Biochemistry. 115 - 122. 131. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890462956&partnerID=MN8TOARS . 10.1016/j.jinorgbio.2013.11.005 . Journal of Inorganic Biochemistry

Unveiling the Interaction of Vanadium Compounds with Human Serum Albumin by Using1H STD NMR and Computational Docking Studies

Dias, David M.; Rodrigues, João P. G. L. M.; Domingues, Neuza S.; Bonvin, Alexandre M. J. J.; Castro, M. Margarida C. A., European Journal of Inorganic Chemistry. 4619 - 4627. 26. 2013. 2013. http://dx.doi.org/10.1002/ejic.201300419 . 10.1002/ejic.201300419 . European Journal of Inorganic Chemistry

Mitochondrial Dysfunction Is the Focus of Quaternary Ammonium Surfactant Toxicity to Mammalian Epithelial Cells

Inácio, Ângela S.; Costa, Gabriel N.; Domingues, Neuza S.; Santos, Maria S.; Moreno, António J. M.; Vaz, Winchil L. C.; Vieira, Otília V., Antimicrobial Agents and Chemotherapy. 2631 - 2639. 6. 57. 2013. http://dx.doi.org/10.1128/aac.02437-12 . 10.1128/aac.02437-12 . Antimicrobial Agents and Chemotherapy

Mitochondrial dysfunction is the focus of quaternary ammonium surfactant toxicity to mammalian epithelial cells

Inácio, A.S.; Costa, G.N.; Domingues, N.S.; Santos, M.S.; Moreno, A.J.M.; Vaz, W.L.C.; Vieiraa, O.V., Antimicrobial Agents and Chemotherapy. 2631 - 2639. 6. 57. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877862108&partnerID=MN8TOARS . 10.1128/AAC.02437-12 . Antimicrobial Agents and Chemotherapy

All projects

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Information of exclusive responsibility of the researcher 19-01-2025 , from platform CIÊNCIAVITAE.

2019/01/26 - 2022

Re-Pair - A novel mechanism to re-pair HFpEF and endothelial damage

Re-Pair - A novel mechanism to re-pair HFpEF and endothelial damage

Researcher

2018/01/01 - 2018/12/31

The role of cholesteryl hemiesters in the etiology, development and instability of atheromata

UID/Multi/ 04462/2013

Integration into Research Grant Fellow

2017/01/01 - 2017/12/31

Exocytosis of Dysfunctional Lysosomes as a New Paradigm Shift in the Pathogenesis of Atherosclerosis.

PTDC/MED-PAT/ 29395/2017

PhD Student Fellow

Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas

2016/01/01 - 2019/12/31

New Targets in DIAstolic heart failure: from coMOrbidities to persoNalizeD medicine

SAICTPAC/0047/2015

Integration into Research Grant Fellow

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