Paula Laranjeira

CD8+ Treg cells play a role in the obesity-associated insulin resistance

Pedro Barbosa; Aryane Pinho; André Lázaro; Daniela Rosendo-Silva; Diogo Paula; José Campos; José G. Tralhão; et al, Life Sciences. 2024. http://dx.doi.org/10.1016/j.lfs.2023.122306 . 10.1016/j.lfs.2023.122306 . Life Sciences

Whole Blood and Plasma-Based Lipid Profiling Reveals Distinctive Metabolic Changes in Systemic Lupus Erythematosus and Systemic Sclerosis

Helena Beatriz Ferreira; Tânia Melo; Inês M. S. Guerra; Ana S. P. Moreira; Paula Laranjeira; Artur Paiva; Laura Goracci; et al, Journal of Proteome Research. 2023. https://doi.org/10.1021/acs.jproteome.3c00321 . 10.1021/acs.jproteome.3c00321 . Journal of Proteome Research

Umbilical-Cord-Derived Mesenchymal Stromal Cells Modulate 26 Out of 41 T Cell Subsets from Systemic Sclerosis Patients

Paula Laranjeira; Francisco dos Santos; Maria João Salvador; Irina N. Simões; Carla M. P. Cardoso; Bárbara M. Silva; Helena Henriques-Antunes; et al, Biomedicines. 2023. https://doi.org/10.3390/biomedicines11051329 . 10.3390/biomedicines11051329 . Biomedicines

Reduced numbers of regulatory T cells in chronic heart failure seems not to be restored by cardiac resynchronization therapy

Sílvia Martins; Natália António; Tiago Carvalheiro; Paula Laranjeira; Ricardo Rodrigues; Lino Gonçalves; Cândida Tomaz; Artur Paiva, BMC Cardiovascular Disorders. 2023. https://doi.org/10.1186/s12872-023-03109-x . 10.1186/s12872-023-03109-x . BMC Cardiovascular Disorders

Human Bone Marrow Mesenchymal Stromal/Stem Cells Regulate the Proinflammatory Response of Monocytes and Myeloid Dendritic Cells from Patients with Rheumatoid Arthritis

Paula Laranjeira; Mónia Pedrosa; Cátia Duarte; Susana Pedreiro; Brígida Antunes; Tânia Ribeiro; Francisco dos Santos; et al, Pharmaceutics. 2022. https://doi.org/10.3390/pharmaceutics14020404 . 10.3390/pharmaceutics14020404 . Pharmaceutics

A single dose of COVID-19 vaccine induces a strong T cell and B cell response in healthcare professionals recovered from SARS-CoV-2 infection

Paula Laranjeira; Tiago Rodrigues; Ana Silva; Pedro Barbosa; Teresa Reis; Cristiana Lopes; Aryane Pinho; et al, Clinical and Experimental Medicine. 2022. https://doi.org/10.1007/s10238-022-00801-8 . 10.1007/s10238-022-00801-8 . published Clinical and Experimental Medicine

Immunoparalysis in critically ill children

Neves, Filipa Loureiro; Amaral, Mariana Nunes Gonçalves Afonso; Silva, Sandra Filomena Durães da; Silva, Isabel Maria Melo; Laranjeira, Paula Margarida dos Santos; Pinto, Carla Regina de Jesus; Paiva, Artur Augusto; Dias, Andrea Sofia da Silva; Coelho, Maria Leonor Almeida Carvalho Vieira, Immunology. 2022. http://dx.doi.org/10.1111/imm.13595 . 10.1111/imm.13595 . Immunology

Successful desensitization to alemtuzumab, with flow cytometric analysis of peripheral blood cells

Costa Carvalho, J; Macário, MC; Batista, S; Alen Coutinho, I; Laranjeira, P; Loureiro, C; Paiva, A; Todo Bom, A, Journal of Investigational Allergy and Clinical Immunology. 6. 32. 2022. http://dx.doi.org/10.18176/jiaci.0795 . 10.18176/jiaci.0795 . accepted Journal of Investigational Allergy and Clinical Immunology

Extensive Phenotypic Characterization of T Cells Infiltrating Liver Metastasis from Colorectal Cancer: A Potential Role in Precision Medicine

Sampaio-Ribeiro, Gabriela; Ana Ruivo; Ana Silva; Ana Lúcia Santos; Rui Caetano Oliveira; Paula Laranjeira; Maria Augusta Cipriano; José Guilherme Tralhão; Artur Paiva, Cancers. 6069 - 6069. 24. 14. 2022. http://dx.doi.org/10.3390/cancers14246069 . 10.3390/cancers14246069 . Cancers

Hypothermic Preservation of Adipose-Derived Mesenchymal Stromal Cells as a Viable Solution for the Storage and Distribution of Cell Therapy Products

André Branco; Ana L. Tiago; Paula Laranjeira; Maria C. Carreira; João C. Milhano; Francisco dos Santos; Joaquim M. S. Cabral; et al, Bioengineering. 2022. https://doi.org/10.3390/bioengineering9120805 . 10.3390/bioengineering9120805 . Bioengineering

Bone marrow follicular-like T cells in monoclonal gammopathies

Ana Silva; Sandra Silva; Isabel Silva; Susana Santos; Paula Laranjeira; Catarina Geraldes; Helena Silva; et al, Cytometry Part B: Clinical Cytometry. 2021. https://doi.org/10.1002/cyto.b.22029 . 10.1002/cyto.b.22029 . Cytometry Part B: Clinical Cytometry

Elevated soluble TNFa levels and upregulated TNFa mRNA expression in purified peripheral blood monocyte subsets associated with high-grade hepatocellular carcinoma

Martín-Sierra, C.; Martins, R.; Coucelo, M.; Abrantes, A. M.; Oliveira, R. C.; Tralhão, J. G.; Botelho, M. F.; et al, Journal of Inflammation. 1. 17. 2020. http://dx.doi.org/10.1186/s12950-020-00243-7 . 10.1186/s12950-020-00243-7 . published Journal of Inflammation

Tumor Resection Induces Alterations on Serum Phospholipidome of Liver Cancer Patients

Martín-Sierra, Carmen; Colombo, Simone; Martins, Ricardo; Laranjeira, Paula; Melo, Tânia; Abrantes, Ana Margarida; Oliveira, Rui Caetano; et al, Lipids. 2020. http://dx.doi.org/10.1002/lipd.12221 . 10.1002/lipd.12221 . published Lipids

Functional Impairment of Circulating FceRI+ Monocytes and Myeloid Dendritic Cells in Hepatocellular Carcinoma and Cholangiocarcinoma Patients

Laranjeira, Paula, 2019. http://dx.doi.org/10.1002/cyto.b.21777 . 10.1002/cyto.b.21777 .

Functional and Phenotypic Characterization of Tumor-Infiltrating Leukocyte Subsets and Their Contribution to the Pathogenesis of Hepatocellular Carcinoma and Cholangiocarcinoma

Martín-Sierra, C.; Martins, R.; Laranjeira, P.; Coucelo, M.; Abrantes, A.M.; Oliveira, R.C.; Tralhão, J.G.; et al, Translational Oncology. 1468 - 1479. 11. 12. 2019. http://dx.doi.org/10.1016/j.tranon.2019.07.019 . 10.1016/j.tranon.2019.07.019 . published Translational Oncology

Immunomodulatory effect of human bone marrow-derived mesenchymal stromal/stem cells on peripheral blood T cells from rheumatoid arthritis patients

Mónia Pedrosa; Joana Gomes; Paula Laranjeira; Cátia Duarte; Susana Pedreiro; Brígida Antunes; Tânia Ribeiro; et al, Journal of Tissue Engineering and Regenerative Medicine. 2019. https://doi.org/10.1002/term.2958 . 10.1002/term.2958 . Journal of Tissue Engineering and Regenerative Medicine

Lipoxidation and cancer immunity

C. Martín-Sierra; P. Laranjeira; M.R. Domingues; A. Paiva, Redox Biology. 101103 - 101103. 2019. https://doi.org/10.1016/j.redox.2019.101103 . 10.1016/j.redox.2019.101103 . Redox Biology

CD43 and CD49d from the B-Cell Chronic Lymphoproliferative Disorders Diagnostic Panel Are Useful to Detect Erythroid Dysplasia

Laranjeira, Paula, Cytometry Part B: Clinical Cytometry. 2019. http://dx.doi.org/10.1002/cyto.b.21792 . 10.1002/cyto.b.21792 . Cytometry Part B: Clinical Cytometry

Amniotic membrane extract differentially regulates human peripheral blood T cell subsets, monocyte subpopulations and myeloid dendritic cells

Paula Laranjeira; Marta Duque; Martin Vojtek; Maria J. Inácio; Isabel Silva; Ana C. Mamede; Mafalda Laranjo; et al, Cell and Tissue Research. 459 - 476. 2. 373. 2018. https://doi.org/10.1007/s00441-018-2822-1 . 10.1007/s00441-018-2822-1 . Cell and Tissue Research

Impact of cardiac resynchronization therapy on circulating IL-17 producing cells in patients with advanced heart failure.

Laranjeira, Paula, Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing. 2018. https://doi.org/10.1007/s10840-018-0491-3 . 10.1007/s10840-018-0491-3 . Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

Modulation of the inflammatory response of immune cells in human peripheral blood by oxidized arachidonoyl aminophospholipids

Simone Colombo; Carmen Martín-Sierra; Tânia Melo; Paula Laranjeira; Artur Paiva; Pedro Domingues; M. Rosário Domingues, Archives of Biochemistry and Biophysics. 64 - 71. 660. 2018. https://doi.org/10.1016/j.abb.2018.10.003 . 10.1016/j.abb.2018.10.003 . Archives of Biochemistry and Biophysics

Frequency and functional activity of Th17, Tc17 and other T-cell subsets in Systemic Lupus Erythematosus

Henriques, Ana; Inês, Luís; Couto, Maura; Pedreiro, Susana; Santos, Catarina; Magalhães, Mariana; Santos, Paulo; et al, To compare frequency and functional activity of peripheral blood (PB) Th(c)17, Th(c)1 and Treg cells and the amount of type 2 cytokines mRNA we recruited SLE patients in active (n = 15) and inactive disease (n = 19) and healthy age- and gender-matched controls (n = 15). The study of Th(c)17, Th(c)1 and Treg cells was done by flow cytometry and cytokine mRNA by real-time PCR. Compared to NC, SLE pa. 97 - 103. 1. 264. 2010. http://hdl.handle.net/10174/21618 . 10.1016/j.cellimm.2010.05.004 . To compare frequency and functional activity of peripheral blood (PB) Th(c)17, Th(c)1 and Treg cells and the amount of type 2 cytokines mRNA we recruited SLE patients in active (n = 15) and inactive disease (n = 19) and healthy age- and gender-matched controls (n = 15). The study of Th(c)17, Th(c)1 and Treg cells was done by flow cytometry and cytokine mRNA by real-time PCR. Compared to NC, SLE pa