Publications
Information about journal articles, updated at 03-11-2024, from platform CIÊNCIAVITAE.
Comparative Analysis of Retinal Organotypic Cultures and In Vivo Axotomized Retinas
María José González-Riquelme; Fernando Lucas-Ruiz; Caridad Galindo-Romero; Raquel Boia; António Francisco Ambrósio; Manuel Vidal-Sanz; Ana Raquel Santiago; Marta Agudo-Barriuso, International Journal of Molecular Sciences. 2023. https://doi.org/10.3390/ijms24043481 . 10.3390/ijms24043481 . International Journal of Molecular Sciences
Neuroinflammation and gliosis in the injured and contralateral retinas after unilateral optic nerve crush
Cabrera-Maqueda, José María; Boia, Raquel; Lucas-Ruiz, Fernando; González-Riquelme, María José; Ambrósio, António Francisco; Santiago, Ana Raquel; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta; Galindo-Romero, Caridad, Experimental Eye Research. 235. 2023. http://dx.doi.org/10.1016/j.exer.2023.109627 . 10.1016/j.exer.2023.109627 . Experimental Eye Research
Maternal diabetes affects rat offspring retinal structure and function: Sex-specific vulnerabilities at infancy
Realinho, Ana M.; Boia, Raquel; Paiva, Beatriz; Correia, Raquel G.; Gaspar, Rita; Ambrósio, António F.; Baptista, Filipa I., Life Sciences. 327. 2023. http://dx.doi.org/10.1016/j.lfs.2023.121852 . 10.1016/j.lfs.2023.121852 . Life Sciences
Attention-Deficit/Hyperactivity Disorder animal model presents retinal alterations and methylphenidate has a differential effect in ADHD versus control conditions (under revision)
Sanches, Eliane Swely; Boia, Raquel; Silva, Ana Paula; Leitão, Ricardo Alexandre; Medeiros, Maria; Md; Sanches, Eliane S.; et al, Antioxidants. 4. 12. 2023. http://dx.doi.org/10.3390/antiox12040937 . 10.3390/antiox12040937 . under revision Antioxidants
Course of retinal ganglion cell loss and microglial activation in two models of neuronal degeneration
Riquelme, Maria Josefa Gonzalez; Lucas-Ruiz, Fernando; Boia, Raquel; Santiago, Ana Raquel; Vidal-Sanz, Manuel; Galindo-Romero, Caridad; Agudo-Barriuso, Marta, Acta Ophthalmologica. 2022. https://publons.com/wos-op/publon/54356176/ . 10.1111/J.1755-3768.2022.211 . Acta Ophthalmologica
Intraocular implants loaded with A3R agonist rescue retinal ganglion cells from ischemic damage
Boia, Raquel; Dias, Paulo A.N.; Galindo-Romero, Caridad; Ferreira, Hugo; Aires, Inês D.; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta; et al, Journal of Controlled Release. 469 - 481. 343. 2022. http://dx.doi.org/10.1016/j.jconrel.2022.02.001 . 10.1016/j.jconrel.2022.02.001 . Journal of Controlled Release
Microglial Extracellular Vesicles as Vehicles for Neurodegeneration Spreading
Aires, Inês Dinis; Ribeiro-Rodrigues, Teresa; Boia, Raquel; Ferreira-Rodrigues, Magda; Girão, Henrique; Ambrósio, António Francisco; Santiago, Ana Raquel, Biomolecules. 6. 11. 2021. http://dx.doi.org/10.3390/biom11060770 . 10.3390/biom11060770 . Biomolecules
Keep an eye on adenosine: Its role in retinal inflammation
Santiago, Ana Raquel; Madeira, Maria H.; Boia, Raquel; Aires, Inês Dinis; Rodrigues-Neves, Catarina; Santos, Paulo Fernando; Ambrósio, António Francisco, Pharmacology & Therapeutics. 2020. http://dx.doi.org/10.1016/j.pharmthera.2020.107513 . 10.1016/j.pharmthera.2020.107513 . Pharmacology & Therapeutics
Neuroprotective Strategies for Retinal Ganglion Cell Degeneration: Current Status and Challenges Ahead
Boia, Raquel; Ruzafa, Noelia; Aires, Inês Dinis; Pereiro, Xandra; Ambrósio, António Francisco; Vecino, Elena; Santiago, Ana Raquel, International Journal of Molecular Sciences. 7. 21. 2020. http://dx.doi.org/10.3390/ijms21072262 . 10.3390/ijms21072262 . International Journal of Molecular Sciences
Exosomes derived from microglia exposed to elevated pressure amplify the neuroinflammatory response in retinal cells
Aires, Inês Dinis; Ribeiro-Rodrigues, Teresa; Boia, Raquel; Catarino, Steve; Girão, Henrique; Ambrósio, António Francisco; Santiago, Ana Raquel, Glia. 2705 - 2724. 12. 68. 2020. http://dx.doi.org/10.1002/glia.23880 . 10.1002/glia.23880 . Glia
Activation of adenosine A3 receptor protects retinal ganglion cells from degeneration induced by ocular hypertension
Boia, Raquel; Salinas-Navarro, Manuel; Gallego-Ortega, Alejandro; Galindo-Romero, Caridad; Aires, Inês D.; Agudo-Barriuso, Marta; Ambrósio, António Francisco; Vidal-Sanz, Manuel; Santiago, Ana Raquel, Cell Death & Disease. 5. 11. 2020. http://dx.doi.org/10.1038/s41419-020-2593-y . 10.1038/s41419-020-2593-y . Cell Death & Disease
Activation of Adenosine A3 Receptor Inhibits Microglia Reactivity Elicited by Elevated Pressure
Ferreira-Silva, Joana; Aires, Inês D.; Boia, Raquel; Ambrósio, António Francisco; Santiago, Ana Raquel, International Journal of Molecular Sciences. 19. 21. 2020. http://dx.doi.org/10.3390/ijms21197218 . 10.3390/ijms21197218 . International Journal of Molecular Sciences
Adenosine A3 receptor agonist prevents the loss of retinal ganglion cells in a glaucoma model
Boia, Raquel; Salinas-Navarro, Manuel; Gallego-Ortega, Alejandro; Galindo-Romero, Caridad; Agudo-Barriuso, Marta; Ambrosio, Antonio F.; Vidal-Sanz, Manuel; Raquel Santiago, Ana, Investigative Ophthalmology & Visual Science. 2019. https://publons.com/wos-op/publon/28944127/ . Investigative Ophthalmology & Visual Science
Blockade of microglial adenosine A2A receptor suppresses elevated pressure-induced inflammation, oxidative stress, and cell death in retinal cells
Aires, Inês Dinis; Boia, Raquel; Rodrigues-Neves, Ana Catarina; Madeira, Maria Helena; Marques, Carla; Ambrósio, António Francisco; Santiago, Ana Raquel, Glia. 896 - 914. 5. 67. 2019. http://dx.doi.org/10.1002/glia.23579 . 10.1002/glia.23579 . Glia
Intravitreal injection of adenosine A2A receptor antagonist reduces neuroinflammation, vascular leakage and cell death in the retina of diabetic mice
Aires, Inês Dinis; Madeira, Maria Helena; Boia, Raquel; Rodrigues-Neves, Ana Catarina; Martins, Joana Margarida; Ambrósio, António Francisco; Santiago, Ana Raquel, Scientific Reports. 1. 9. 2019. http://dx.doi.org/10.1038/s41598-019-53627-y . 10.1038/s41598-019-53627-y . Scientific Reports
Extracellular vesicles released by microglia exposed to elevated hydrostatic pressure promote retinal neural cell loss and microglia reactivity
Santiago, Ana Raquel; Aires, Ines Dinis; Ribeiro-Rodrigues, Teresa; Boia, Raquel; Catarino, Steve; Almeida, Daniela; Girao, Henrique; Ambrosio, Antonio F., Investigative Ophthalmology & Visual Science. 2019. https://publons.com/wos-op/publon/28332477/ . Investigative Ophthalmology & Visual Science
Porous poly(e-caprolactone) implants: A novel strategy for efficient intraocular drug delivery
Boia, Raquel; Dias, Paulo A.N.; Martins, Joana M.; Galindo-Romero, Caridad; Aires, Inês D.; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta; et al, Journal of Controlled Release. 331 - 348. 316. 2019. http://dx.doi.org/10.1016/j.jconrel.2019.09.023 . 10.1016/j.jconrel.2019.09.023 . Journal of Controlled Release
Elevated Pressure Changes the Purinergic System of Microglial Cells
Rodrigues-Neves, Ana C.; Aires, Inês D.; Vindeirinho, Joana; Boia, Raquel; Madeira, Maria H.; Gonçalves, Francisco Q.; Cunha, Rodrigo A.; et al, Frontiers in Pharmacology. 9. 2018. http://dx.doi.org/10.3389/fphar.2018.00016 . 10.3389/fphar.2018.00016 . Frontiers in Pharmacology
Subtle thinning of retinal layers without overt vascular and inflammatory alterations in a rat model of prediabetes
Alves, Mariana R. P.; Boia, Raquel; Campos, Elisa J.; Martins, Joao; Nunes, Sara; Madeira, Maria H.; Santiago, Ana Raquel; et al, Molecular Vision. 353 - 366. 24. 2018. https://publons.com/wos-op/publon/7412815/ . Molecular Vision
Sweet Stress: Coping With Vascular Dysfunction in Diabetic Retinopathy
Santiago, Ana R.; Boia, Raquel; Aires, Inês D.; Ambrósio, António F.; Fernandes, Rosa, Frontiers in Physiology. 9. 2018. http://dx.doi.org/10.3389/fphys.2018.00820 . 10.3389/fphys.2018.00820 . Frontiers in Physiology
Treatment with A2A receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damage
Boia, Raquel; Elvas, Filipe; Madeira, Maria H; Aires, Inês D; Rodrigues-Neves, Ana C; Tralhão, Pedro; Szabó, Eszter C; et al, Cell Death & Disease. e3065 - e3065. 10. 8. 2017. http://dx.doi.org/10.1038/cddis.2017.451 . 10.1038/cddis.2017.451 . Cell Death & Disease
Having a Coffee Break: The Impact of Caffeine Consumption on Microglia-Mediated Inflammation in Neurodegenerative Diseases.
Boia, Raquel, Mediators of inflammation. 2017. http://europepmc.org/abstract/med/28250576 . 10.1155/2017/4761081 . Mediators of inflammation
Therapeutic Opportunities for Caffeine and A2A Receptor Antagonists in Retinal Diseases
Boia, Raquel; Ambrósio, António Francisco; Santiago, Ana Raquel, Ophthalmic Research. 212 - 218. 4. 55. 2016. http://dx.doi.org/10.1159/000443893 . 10.1159/000443893 . Ophthalmic Research
Selective A2A receptor antagonist prevents microglia-mediated neuroinflammation and protects retinal ganglion cells from high intraocular pressure–induced transient ischemic injury
Madeira, Maria H.; Boia, Raquel; Elvas, Filipe; Martins, Tiago; Cunha, Rodrigo A.; Ambrósio, António Francisco; Santiago, Ana Raquel, Translational Research. 112 - 128. 169. 2016. http://dx.doi.org/10.1016/j.trsl.2015.11.005 . 10.1016/j.trsl.2015.11.005 . Translational Research
Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure
Madeira, Maria H.; Elvas, Filipe; Boia, Raquel; Gonçalves, Francisco Q.; Cunha, Rodrigo A.; Ambrósio, António Francisco; Santiago, Ana Raquel, Journal of Neuroinflammation. 1. 12. 2015. http://dx.doi.org/10.1186/s12974-015-0333-5 . 10.1186/s12974-015-0333-5 . Journal of Neuroinflammation
Contribution of Microglia-Mediated Neuroinflammation to Retinal Degenerative Diseases
Madeira, Maria H.; Boia, Raquel; Santos, Paulo F.; Ambrósio, António F.; Santiago, Ana R., Mediators of Inflammation. 1 - 15. 2015. 2015. http://dx.doi.org/10.1155/2015/673090 . 10.1155/2015/673090 . Mediators of Inflammation
5 26 out of 26 Publications
All projects
Information of exclusive responsibility of the researcher 03-11-2024 , from platform CIÊNCIAVITAE.
2023/01 - 2026/12
A new therapeutic approach to leverage vision restoration in glaucoma.
n.a.
Principal investigator
Funders: Medalhas de Honra L’Oréal para as Mulheres na Ciência
2023/03/12
Deciphering the role of Piezo1 mechanosensitive channel in microglia-mediated glaucomatous neurodegeneration
2022.01354.PTDC
Researcher
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia
2016/06 - 2017/07
Exosomes as amplifiers of inflammation: microglia-Müller cell communication in glaucoma.
GAI-Santander Totta 2016_224
Researcher
Funders: Universidade de Coimbra Faculdade de Medicina
2016/07 - 2019/12
Biodegradable intravitreal porous implants for the extended release of A3 adenosine receptor agonist for the treatment of glaucoma
PTDC/NEU-OSD/3123/2014
Researcher
Funders: Fundação para a Ciência e a Tecnologia
2015/10 - 2019/09
Activation of A3 adenosine receptor using intraocular biodegradable implants as a strategy for the treatment of glaucoma
PD/BD/114115/2015
PhD Student Fellow
Funders: Fundação para a Ciência e a Tecnologia
2015/12 - 2018/02
Managing inflammation in diabetic retinopathy by adenosine A2A receptor blockade
US2083156314
Researcher
Funders: Global Ophthalmology Awards Program - Bayer HealthCare
2015/04 - 2015/10
Biodegradable intravitreal porous implants for extended release of A3 adenosine receptor agonist for the protection of retinal ganglion cells
ASantiago.GAI2015
Researcher
Funders: Universidade de Coimbra Faculdade de Medicina
2014/01 - 2015/12
The potential protective effect of caffeine in the retina: relevance for the treatment of glaucoma.
n/a
Researcher
Funders: MANUEL RUI AZINHAIS NABEIRO LDA
2013/06 - 2015/09
From neuroinflammation control to neuroprotection: blocking adenosine A2A receptor for the treatment of glaucoma.
PTDC/BIM-MEC/0913/2012
Research Fellow
Funders: Fundação para a Ciência e a Tecnologia
2013/05 - 2013/10
Adenosine A3 receptor: a new therapeutic target for the treatment of glaucoma?
GAI Santiago06.01.13
Researcher
Funders: Universidade de Coimbra Faculdade de Medicina
5 10 out of 10 projects
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