Publications
Information about journal articles, updated at 01-12-2024, from platform CIÊNCIAVITAE.
Enhancing Safety and Efficacy of Senolytic Therapies with Advanced Controlled Release Strategies
Francisco, Vitor; Andreia Marques; David Sanfeliu-Redondo; Ines Tomé; Rosa, Susana; Jordi Gracia-Sancho; Ferreira, Lino, Nature Communications. 2025. submitted Nature Communications
Engineering extracellular vesicles to transiently permeabilize the blood-brain barrier
Tomatis, Francesca; Rosa, Susana; Susana Margarida Neto Simões; Barão, Marta; Carlos Jesus; Novo, João Pedro; Emanuel Barth; Manja Mars; Ferreira, Lino, Journal of Nanobiotechnology. 2024. accepted Journal of Nanobiotechnology
Blood–brain barrier dysfunction in aging is mediated by brain endothelial senescence. J.P. Novo, A.C Caetano, L. Gee, I. Moreira, D. Jurk, S. Rosa*, L. Silva Ferreira*. *Authors with equal contribution. Corresponding and Co-senior authors.
Novo, João Pedro; Gee, Lucy; Caetano, Carolina A.; Tomé, Inês; Vilaça, Andreia; von Zglinicki, Thomas; Moreira, Irina S.; et al, Aging Cell. 2024. http://dx.doi.org/10.1111/acel.14270 . 10.1111/acel.14270 . Aging Cell
Nanoparticle-encapsulated retinoic acid for the modulation of bone marrow hematopoietic stem cell niche. Emanuel Quartin*, Susana Rosa* , Sara Gonzalez-Anton, Laura Mosteo Lopez , Vitor Francisco , Delfim Duarte, Cristina Lo Celso, Ricardo Pires das Neves, Lino Ferreira . *Authors with equal contribution
Quartin, Emanuel; Rosa, Susana; Gonzalez-Anton, Sara; Mosteo Lopez, Laura; Francisco, Vitor; Duarte, Delfim; Lo Celso, Cristina; Pires das Neves, Ricardo; Ferreira, Lino, Bioactive Materials. 311 - 325. 34. 2024. http://dx.doi.org/10.1016/j.bioactmat.2023.12.017 . 10.1016/j.bioactmat.2023.12.017 . accepted Bioactive Materials
FLEXIBLE PIEZOELECTRIC PATCHES FOR IMPROVEMENT OF HEART TISSUE ACTIVITY
Monteiro, Luis Miguel; Gouveia, Pedro J.; Rosa, Susana; Vasques-Novoa, Francisco; Gomes, Rita; Bardi, Ifigeneia; Ricotti, Leonardo; et al, Tissue Engineering Part A. 2022. https://publons.com/wos-op/publon/54503179/ . Tissue Engineering Part A
Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor Cells
Praça, Catarina; Rosa, Susana C.; Sevin, Emmanuel; Cecchelli, Romeo; Dehouck, Marie-Pierre; Ferreira, Lino S., Stem Cell Reports. 599 - 611. 4. 13. 2019. http://dx.doi.org/10.1016/j.stemcr.2019.08.002 . 10.1016/j.stemcr.2019.08.002 . published Stem Cell Reports
A High-Throughput Screening Method to Identify Compounds Displaying Human Vascular Embryonic Toxicity
Rosa, Susana; Pitrez, Patrícia; Fernandes, Hugo; Ferreira, Lino, Current Protocols in Stem Cell Biology. 1. 50. 2019. http://dx.doi.org/10.1002/cpsc.93 . 10.1002/cpsc.93 . published Current Protocols in Stem Cell Biology
Unveiling the molecular crosstalk in a human induced pluripotent stem cell-derived cardiac model
Abecasis, Bernardo; Gomes-Alves, Patrícia; Rosa, Susana; Gouveia, Pedro J.; Ferreira, Lino; Serra, Margarida; Alves, Paula M., Biotechnology and Bioengineering. 1245 - 1252. 5. 116. 2019. http://dx.doi.org/10.1002/bit.26929 . 10.1002/bit.26929 . published Biotechnology and Bioengineering
Functional characterization of iPSC-derived arterial- and venous-like endothelial cells.
Rosa, Susana; Praça, Catarina; Pitrez, Patricia R.; Gouveia, Pedro J.; Aranguren, X.L.; Ricotti, L.; Ferreira, Lino S., Scientific reports. 2019. http://europepmc.org/articles/PMC6405900 . 10.1038/s41598-019-40417-9 . Scientific reports
Flexible nanofilms coated with aligned piezoelectric microfibers preserve the contractility of cardiomyocytes
Gouveia, P. José; Rosa, S.; Ricotti, L.; Abecasis, B.; Almeida, H.V.; Monteiro, L.; Nunes, J.; et al, Biomaterials. 213 - 228. 139. 2017. http://dx.doi.org/10.1016/j.biomaterials.2017.05.048 . 10.1016/j.biomaterials.2017.05.048 . published Biomaterials
High-throughput identification of small molecules that affect human embryonic vascular development
Rosa, Susana*; Vazão, H.*; Barata, Tânia; Costa, Ricardo; Honório, Inês; Pitrez, Patrícia R.; Papatsenko, Dimitri; et al, Proceedings of the National Academy of Sciences. E3022 - E3031. 15. 114. 2017. http://dx.doi.org/10.1073/pnas.1617451114 . 10.1073/pnas.1617451114 . Proceedings of the National Academy of Sciences
Vascular disease modeling using induced pluripotent stem cells: Focus in Hutchinson-Gilford Progeria Syndrome.
Pitrez PR; Rosa SC; Praça C; Ferreira L, Biochemical and biophysical research communications. 2016. http://europepmc.org/abstract/med/26474704 . 10.1016/j.bbrc.2015.10.014 . Biochemical and biophysical research communications
Diabetes-induced osteoarthritis: role of hyperglycemia in joint destruction.
Mendes AF; Rosa SC; Rufino AT; Ribeiro M; Judas F, BMC musculoskeletal disorders. 2015. http://europepmc.org/abstract/PMC/PMC4674852 . BMC musculoskeletal disorders
Development of an in Vitro Dendritic Cell-Based Test for Skin Sensitizer Identification.
Rosa, Susana, Chem Res Toxicol. 2013. http://www.ncbi.nlm.nih.gov/pubmed/23445166 . 10.1021/tx300472d . Chem Res Toxicol
Expression and function of K(ATP) channels in normal and osteoarthritic human chondrocytes: Possible role in glucose sensing
Rufino, A.T.; Rosa, S.C.; Judas, F.; Mobasheri, A.; Lopes, M.C.; Mendes, A.F., Journal of Cellular Biochemistry. 1879 - 1889. 8. 114. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879133940&partnerID=MN8TOARS . 10.1002/jcb.24532 . Journal of Cellular Biochemistry
Profiling changes triggered during maturation of dendritic cells: a lipidomic approach
Rosa, Susana, Analytical and Bioanalytical Chemistry. 2012. http://www.ncbi.nlm.nih.gov/pubmed/22402731 . DOI:10.1007/s00216-012-5843-8 . Analytical and Bioanalytical Chemistry
Role of glucose as a modulator of anabolic and catabolic gene expression in normal and osteoarthritic human chondrocytes
Rosa, S.C.; Rufino, A.T.; Judas, F.M.; Tenreiro, C.M.; Lopes, M.C.; Mendes, A.F., Journal of Cellular Biochemistry. 2813 - 2824. 10. 112. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053207223&partnerID=MN8TOARS . 10.1002/jcb.23196 . Journal of Cellular Biochemistry
Expression and function of the insulin receptor in normal and osteoarthritic human chondrocytes: Modulation of anabolic gene expression, glucose transport and GLUT-1 content by insulin
Rosa, S.C.; Rufino, A.T.; Judas, F.; Tenreiro, C.; Lopes, M.C.; Mendes, A.F., Osteoarthritis and Cartilage. 719 - 727. 6. 19. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955972378&partnerID=MN8TOARS . 10.1016/j.joca.2011.02.004 . Osteoarthritis and Cartilage
Screening of five essential oils for identification of potential inhibitors of IL-1-induced Nf-B activation and no production in human chondrocytes: Characterization of the inhibitory activity of-pinene
Neves, Â.; Rosa, S.; Gonçalves, J.; Rufino, A.; Judas, F.; Salgueiro, L.; Lopes, M.C.; Cavaleiro, C.; Mendes, A.F., Planta Medica. 303 - 308. 3. 76. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77049099601&partnerID=MN8TOARS . 10.1055/s-0029-1186085 . Planta Medica
Assessment of strategies to increase chondrocyte viability in cryopreserved human osteochondral allografts: evaluation of the glycosylated hydroquinone, arbutin
Rosa, S.C.; Gonçalves, J.; Judas, F.; Lopes, C.; Mendes, A.F., Osteoarthritis and Cartilage. 1657 - 1661. 12. 17. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449635135&partnerID=MN8TOARS . 10.1016/j.joca.2009.08.016 . Osteoarthritis and Cartilage
Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilage
Rosa, S.C.; Gonçalves, J.; Judas, F.; Mobasheri, A.; Lopes, C.; Mendes, A.F., Arthritis Research and Therapy. 3. 11. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649439168&partnerID=MN8TOARS . 10.1186/ar2713 . Arthritis Research and Therapy
Nitric oxide synthase isoforms and NF-¿B activity in normal and osteoarthritic human chondrocytes: Regulation by inducible nitric oxide
Rosa, S.C.; Judas, F.; Lopes, M.C.; Mendes, A.F., Nitric Oxide - Biology and Chemistry. 276 - 283. 3. 19. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-52149088545&partnerID=MN8TOARS . 10.1016/j.niox.2008.07.005 . Nitric Oxide - Biology and Chemistry
Chondrocyte Viability in Fresh and Frozen Large Human Osteochondral Allografts: Effect of Cryoprotective Agents
Judas, F.; Rosa, S.; Teixeira, L.; Lopes, C.; Ferreira Mendes, A., Transplantation Proceedings. 2531 - 2534. 8. 39. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35348884844&partnerID=MN8TOARS . 10.1016/j.transproceed.2007.07.028 . Transplantation Proceedings
Elevated glucose changes the expression of ionotropic glutamate receptor subunits and impairs calcium homeostasis in retinal neural cells
Santiago, A.R.; Rosa, S.C.; Santos, P.F.; Cristóvão, A.J.; Barber, A.J.; Ambrósio, A.F., Investigative Ophthalmology and Visual Science. 4130 - 4137. 9. 47. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749133437&partnerID=MN8TOARS . 10.1167/iovs.06-0085 . Investigative Ophthalmology and Visual Science
5 24 out of 24 Publications
All projects
Information of exclusive responsibility of the researcher 01-12-2024 , from platform CIÊNCIAVITAE.
2023/03/01
Nanomedicine and trojan cells for leukemic niche intervention_ 2022.05946.PTDC
2022.05946.PTDC
Researcher
2023/03/01
Polymer brush grafted exosomes for microRNA delivery through blood brain barrier (BBB)_2022.02803.PTDC
2022.02803.PTDC
Researcher
2022/01/21
CARESS - Cardiac aging through the lens of Hutchinson-Gilford (Progeria) Syndrome
CARESS - EXPL/MED-OUT/1205/2021
Other
Universidade de Coimbra
Funders: Fundação para a Ciência e a Tecnologia
2021/03/01
A therapeutic strategy to fight blood-brain-barrier (BBB) ageing
PTDC/BTM-SAL/5174/2020
Principal investigator
Funders: Fundação para a Ciência e a Tecnologia
2021/01/01 - 2023/12/31
European project Twinning RESETAgeing (Ref: 952266)
Ref: 952266
Researcher
2015/07/01 - 2020/06/30
European ERA-Chair project in ageing (Ref: 669088)_ERA@UC
GA 669088
Researcher
2015/01/01 - 2016/04/30
Evaluation of in-vitro tests to reduce animal testing in drug toxicology studies
QREN 38977/2014
Other
Funders: Agência Nacional de Inovação SA
2014/12/01 - 2018/05/31
CARDIOSTEM: Tecidos cardíacos e terapias baseadas em células estaminais para aplicações cardiovasculares
MITP-TB/ECE/0013/2013
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Unidade Local de Saúde São José EPE; Instituto de Biologia Experimental e Tecnológica; Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento; Universidade de Lisboa Faculdade de Medicina Veterinária
Funders: Fundação para a Ciência e a Tecnologia
2014/12/01 - 2017/11/03
CARDIOSTEM- Engineered cardiac tissues and stem cell-based therapies for cardiovascular applications
info:eu-repo/grantAgreement/FCT/5665-PICT/137185/PT
Researcher
Funders: Fundação para a Ciência e a Tecnologia
2013 - 2013
EUMINAfab- “High-Throughput Array to GUIDE the Specification of Cells- HTA-GUIDE
EuminaFab 1153
Researcher
Funders: FP7 Capacities Specific Programme.
2013/07 - 2014/09
Human cardiac engineered tissue for toxicity assessment- CARDIOTOX
grant.Provided by PTCRIS: 126384
Principal investigator
Funders: Fundação para a Ciência e a Tecnologia
2011/06/01 - 2011/12/31
Heart regeneration by embryonic vascular cells and a biomimetic scaffold (PTDC/SAU-BEB/098468/2008)
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/98468/PT
Post-doc Fellow
Funders: Fundação para a Ciência e a Tecnologia
2010/06/01 - 2011/05/31
In vitro alternative approach for chemical skin sensitization hazard: an EU legislation demand
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/99762/PT
Research Technician Fellow
Funders: Fundação para a Ciência e a Tecnologia
2009/01/01 - 2009/12/31
METABOLIC ACTIVITY AND VIABILITY OF CHONDROCYTES IN CRYOPRESERVED HUMAN OSTEOCHONDRAL ALLOGRAFTS
PTDC/SAU-OSM/67936/2006
Research Technician Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
5 14 out of 14 projects
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