Publications
Information about journal articles, updated at 01-12-2024, from platform CIÊNCIAVITAE.
O Potencial dos Ácidos Resínicos na Descoberta de Novos Fármacos Antimicrobianos
Vânia Moreira, Boletim da Sociedade Portuguesa de Química. 165 - 171. 170. 47. 2023. http://dx.doi.org/10.52590/m3.p707.a30002710 . 10.52590/m3.p707.a30002710 . Boletim da Sociedade Portuguesa de Química
Ubiquitin-specific protease 7 (USP7): an emerging drug target for cancer treatment
Laura D. Carreira; Rita I. Oliveira; Vânia M. Moreira; Jorge A. R. Salvador, Expert Opinion on Therapeutic Targets. 2023. https://doi.org/10.1080/14728222.2023.2266571 . 10.1080/14728222.2023.2266571 . Expert Opinion on Therapeutic Targets
Probing the Interactions of Thiazole Abietane Inhibitors with the Human Serine Hydrolases ABHD16A and ABHD12
Tiina J. Ahonen; Choa P. Ng; Beatriz Farinha; Bárbara Almeida; Bruno L. Victor; Christopher Reynolds; Eija Kalso; et al, ACS Medicinal Chemistry Letters. 2023. https://doi.org/10.1021/acsmedchemlett.3c00313 . 10.1021/acsmedchemlett.3c00313 . ACS Medicinal Chemistry Letters
Precision Design of Antimicrobial Surfaces
Mullen, Declan; Wan, Xing; Takala, Timo; Saris, Per E; Moreira, Vania, Front. Med. Technol.. 2021. https://doi.org/10.3389/fmedt.2021.640929 . 10.3389/fmedt.2021.640929 . Front. Med. Technol.
Liquorice for pain?
Rae F. Bell; Vânia M. Moreira; Eija A. Kalso; Jari Yli-Kauhaluoma, Therapeutic Advances in Psychopharmacology. 2021. https://doi.org/10.1177/20451253211024873 . 10.1177/20451253211024873 . Therapeutic Advances in Psychopharmacology
29th Annual GP2A Medicinal Chemistry Conference
Jean-Jacques Helesbeux; Laura Carro; Florence O. McCarthy; Vânia M. Moreira; Francesca Giuntini; Niamh O’Boyle; Susan E. Matthews; et al, Pharmaceuticals. 2021. https://doi.org/10.3390/ph14121278 . 10.3390/ph14121278 . Pharmaceuticals
Non-leaching, Highly Biocompatible Nanocellulose Surfaces That Efficiently Resist Fouling by Bacteria in an Artificial Dermis Model
Moreira, Vania, ACS Applied Bio Materials. 2020. http://dx.doi.org/10.1021/acsabm.0c00203 . 10.1021/acsabm.0c00203 . ACS Applied Bio Materials
Mitoxantrone, pixantrone and mitoxantrone (2-hydroxyethyl)piperazine are toll-like receptor 4 antagonists, inhibit NF-¿B activation, and decrease TNF-alpha secretion in primary microglia
Maiju Rinne; Kert Mätlik; Tiina Ahonen; Fabio Vedovi; Giovanni Zappia; Vânia M. Moreira; Jari Yli-Kauhaluoma; et al, European Journal of Pharmaceutical Sciences. 105493 - 105493. 154. 2020. https://doi.org/10.1016/j.ejps.2020.105493 . 10.1016/j.ejps.2020.105493 . European Journal of Pharmaceutical Sciences
Dehydroabietylamine-Based Cellulose Nanofibril Films: A New Class of Sustainable Biomaterials for Highly Efficient, Broad-Spectrum Antimicrobial Effects
Ghada Hassan; Nina Forsman; Xing Wan; Leena Keurulainen; Luis M. Bimbo; Leena-Sisko Johansson; Nina Sipari; et al, ACS Sustainable Chemistry & Engineering. 5002 - 5009. 5. 7. 2019. https://doi.org/10.1021%2Facssuschemeng.8b05658 . 10.1021/acssuschemeng.8b05658 . ACS Sustainable Chemistry & Engineering
Pyrazine-Fused Triterpenoids Block the TRPA1 Ion Channel in Vitro and Inhibit TRPA1-Mediated Acute Inflammation in Vivo
Ilari Mäki-Opas; Mari Hämäläinen; Lauri J. Moilanen; Raisa Haavikko; Tiina J. Ahonen; Sami Alakurtti; Vânia M. Moreira; et al, ACS Chemical Neuroscience. 2848 - 2857. 10. 2019. https://doi.org/10.1021/acschemneuro.9b00083 . 10.1021/acschemneuro.9b00083 . ACS Chemical Neuroscience
Discovery of 12-Thiazole Abietanes as Selective Inhibitors of the Human Metabolic Serine Hydrolase hABHD16A
Tiina J. Ahonen; Juha R. Savinainen; Jari Yli-Kauhaluoma; Eija Kalso; Jarmo T. Laitinen; Vânia M. Moreira, ACS Medicinal Chemistry Letters. 1269 - 1273. 9. 2018. https://doi.org/10.1021/acsmedchemlett.8b00442 . 10.1021/acsmedchemlett.8b00442 . ACS Medicinal Chemistry Letters
Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1
Laura E. Kolsi; Ana S. Leal; Jari Yli-Kauhaluoma; Karen T. Liby; Vânia M. Moreira, Scientific Reports. 1. 8. 2018. https://doi.org/10.1038/s41598-018-34131-1 . 10.1038/s41598-018-34131-1 . Scientific Reports
Catalytic, Tunable, One-Step Bismuth(III) Triflate Reaction with Alcohols: Dehydration Versus Dimerization
Laura E. Kolsi; Jari Yli-Kauhaluoma; Vânia M. Moreira, ACS Omega. 8836 - 8842. 3. 2018. https://doi.org/10.1021/acsomega.8b01401 . 10.1021/acsomega.8b01401 . ACS Omega
Synthesis of 7ß-hydroxy-8-ketone opioid derivatives with antagonist activity at mu- and delta-opioid receptors.
Ahonen TJ; Rinne M; Grutschreiber P; Mätlik K; Airavaara M; Schaarschmidt D; Lang H; et al, European journal of medicinal chemistry. 495 - 507. 151. 2018. https://doi.org/10.1016/j.ejmech.2018.02.074 . 10.1016/j.ejmech.2018.02.074 . European journal of medicinal chemistry
Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative agents.
Moreira, Vania, European journal of medicinal chemistry. 2017. https://doi.org/10.1016/j.ejmech.2017.11.070 . 10.1016/j.ejmech.2017.11.070 . European journal of medicinal chemistry
Regioselective Benzylic Oxidation of Aromatic Abietanes: Application to the Semisynthesis of the Naturally Occurring Picealactones A, B and C
Kolsi, Laura E.; Krogerus, Sara; Brito, Vanessa; Rüffer, Tobias; Lang, Heinrich; Yli-Kauhaluoma, Jari; Silvestre, Samuel M.; Moreira, Vânia M., ChemistrySelect. 7008 - 7012. 24. 2. 2017. http://dx.doi.org/10.1002/slct.201701477 . 10.1002/slct.201701477 . ChemistrySelect
Antibacterial profiling of abietane-type diterpenoids
Andreas Helfenstein; Mikko Vahermo; Dorota A. Nawrot; Fatih Demirci; Gökalp Iscan; Sara Krogerus; Jari Yli-Kauhaluoma; Vânia M. Moreira; Päivi Tammela, Bioorganic & Medicinal Chemistry. 132 - 137. 1. 25. 2017. https://doi.org/10.1016%2Fj.bmc.2016.10.019 . 10.1016/j.bmc.2016.10.019 . Bioorganic & Medicinal Chemistry
Antiprotozoal activity of dehydroabietic acid derivatives against Leishmania donovani and Trypanosoma cruzi
Vahermo, Mikko; Krogerus, Sara; Nasereddin, Abdelmajeed; Kaiser, Marcel; Brun, Reto; Jaffe, Charles L.; Yli-Kauhaluoma, Jari; Moreira, Vânia M., MedChemComm. 457 - 463. 3. 7. 2016. http://dx.doi.org/10.1039/c5md00498e . 10.1039/c5md00498e . MedChemComm
Synthesis and Anti-Proliferative Activity of Sulfanyltriazolylnaphthalenols and Sulfanyltriazolylnaphthalene-1,4-diones
Chaaban, Ibrahim; El Khawass, El Sayeda M.; Abd El Razik, Heba A.; El Salamouni, Nehad S.; Redondo-Horcajo, Mariano; Barasoain, Isabel; Díaz, José Fernando; Yli-Kauhaluoma, Jari; Moreira, Vânia M., Archiv der Pharmazie. 749 - 761. 9. 349. 2016. http://dx.doi.org/10.1002/ardp.201600134 . 10.1002/ardp.201600134 . Archiv der Pharmazie
Betulin Derivatives Effectively Suppress Inflammation in Vitro and in Vivo
Laavola M; Haavikko R; Hämäläinen M; Leppänen T; Nieminen R; Alakurtti S; Moreira VM; Yli-Kauhaluoma J; Moilanen E, Journal of Natural Products. 274 - 280. 79. 2016. https://doi.org/10.1021/acs.jnatprod.5b00709 . 10.1021/acs.jnatprod.5b00709 . Journal of Natural Products
Abietane-Type Diterpenoid Amides with Highly Potent and Selective Activity against Leishmania donovani and Trypanosoma cruzi.
Pirttimaa M; Nasereddin A; Kopelyanskiy D; Kaiser M; Yli-Kauhaluoma J; Oksman-Caldentey KM; Brun R; et al, Journal of Natural Products. 362 - 368. 79. 2016. https://doi.org/10.1021/acs.jnatprod.5b00990 . 10.1021/acs.jnatprod.5b00990 . Journal of Natural Products
Optimization of Invasion-Specific Effects of Betulin Derivatives on Prostate Cancer Cells through Lead Development.
Härmä V; Haavikko R; Virtanen J; Ahonen I; Schukov HP; Alakurtti S; Purev E; et al, PLoS ONE. 10. 2015. https://doi.org/10.1371/journal.pone.0126111 . 10.1371/journal.pone.0126111 . PLoS ONE
New derivatives of dehydroabietic acid target planktonic and biofilm bacteria in Staphylococcus aureus and effectively disrupt bacterial membrane integrity
Moreira, Vania, European Journal of Medicinal Chemistry. 2015. https://doi.org/10.1016/j.ejmech.2015.07.038 . 10.1016/j.ejmech.2015.07.038 . European Journal of Medicinal Chemistry
Synthesis and biological evaluation of new oxadiazoline-substituted naphthalenyl acetates as anticancer agents
Chaaban, Ibrahim; El Khawass, El Sayeda M.; Abd El Razik, Heba A.; El Salamouni, Nehad S.; Redondo-Horcajo, Mariano; Barasoain, Isabel; Diaz, J. Fernando; Yli-Kauhaluoma, Jari; Moreira, Vania M., European journal of medicinal chemistry. 805 - 13. 87. 2014. https://doi.org/10.1016/j.ejmech.2014.10.015 . 10.1016/j.ejmech.2014.10.015 . European journal of medicinal chemistry
Isolation and purification of ent-pimara-8(14),15-diene from engineered Aspergillus nidulans by accelerated solvent extraction combined with HPLC
Bromann, K.; Viljanen, K.; Moreira, V. M.; Yli-Kauhaluoma, J.; Ruohonen, L.; Nakari-Setala, T., Analytical Methods. 1227 - 1234. 4. 6. 2014. https://doi.org/10.1039/C3AY41640B . 10.1039/c3ay41640b . Analytical Methods
(+)-Dehydroabietic Acid, an Abietane-Type Diterpene, Inhibits Staphylococcus aureus Biofilms in Vitro.
Fallarero A; Kujala J; Moreira VM; Rajaratnam M; Skogman M; Vuorela P; Yli-Kauhaluoma J, International Journal of Molecular Sciences. 12054 - 12072. 14. 2013. https://doi.org/10.3390/ijms140612054 . 10.3390/ijms140612054 . International Journal of Molecular Sciences
Novel oleanolic vinyl boronates: Synthesis and antitumor activity
Moreira, Vania M.; Salvador, Jorge A. R.; Simoes, Sergio; Destro, Federica; Gavioli, Riccardo, European Journal of Medicinal Chemistry. 46 - 56. 63. 2013. https://doi.org/10.1016/j.ejmech.2013.01.040 . 10.1016/j.ejmech.2013.01.040 . European Journal of Medicinal Chemistry
Drug repositioning: a machine-learning approach through data integration
Napolitano, Francesco; Zhao, Yan; Moreira, Vania M.; Tagliaferri, Roberto; Kere, Juha; D'Amato, Mauro; Greco, Dario, Journal of Cheminformatics. 5. 2013. https://doi.org/10.1186/1758-2946-5-30 . 10.1186/1758-2946-5-30 . Journal of Cheminformatics
Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs
Salvador, Jorge A. R.; Moreira, Vânia M.; Gonçalves, Bruno M. F.; Leal, Ana S.; Jing, Yongkui, Natural Product Reports. 12. 29. 2012. http://dx.doi.org/10.1039/c2np20060k . 10.1039/c2np20060k . Natural Product Reports
Efficient oxidation of oleanolic acid derivatives using magnesium bis(monoperoxyphthalate) hexahydrate (MMPP): A convenient 2-step procedure towards 12-oxo-28-carboxylic acid derivatives
Salvador, Jorge A R; Moreira, Vânia M; Pinto, Rui M A; Leal, Ana S; Paixão, José A, Beilstein Journal of Organic Chemistry. 164 - 169. 8. 2012. http://dx.doi.org/10.3762/bjoc.8.17 . 10.3762/bjoc.8.17 . Beilstein Journal of Organic Chemistry
Recent Developments in Oxidative Processes in Steroid Chemistry
Jorge A. R. Salvador; Samuel M. Silvestre; Vânia M Moreira, Current Organic Chemistry. 1243 - 1276. 16. 2012. https://doi.org/10.2174/138527212800564204 . Current Organic Chemistry
Bismuth(III) Triflate-Based Catalytic Direct Opening of Oleanolic Hydroxy-¿-lactones to Afford 12-Oxo-28-carboxylic Acids
Salvador, Jorge A. R.; Moreira, Vânia M.; Pinto, Rui M. A.; Leal, Ana S.; Le Roux, Christophe, Advanced Synthesis & Catalysis. 2637 - 2642. 14-15. 353. 2011. http://dx.doi.org/10.1002/adsc.201100155 . 10.1002/adsc.201100155 . Advanced Synthesis & Catalysis
The reaction of azoles with 17-chloro-16-formylandrosta-5,16-dien-3-yl-acetate: Synthesis and structural elucidation of novel 16-azolylmethylene-17-oxoandrostanes.
Vânia M Moreira; Jorge A. R. Salvador; Ana Matos Beja; José A. Paixão, Steroids. 582 - 587. 76. 2011. https://doi.org/10.1016/j.steroids.2011.02.009 . Steroids
3-Oxoandrosta-4,6-dien-17beta-yl-2'-methyl-1H-imidazole-1-carboxylate and 3-oxo-5a-androst-17beta-yl-2'-methyl-1H-imidazole-1-carboxylate: C¿H..p and p¿¿¿p intermolecular interactions
Manuela R. Silva; Vânia M Moreira; Cláudia Cardoso; Ana Matos Beja; Jorge A. R. Salvador, Acta Crystallographica. Section C: Crystal Structure Communications. o88 - o91. C65. 2009. https://doi.org/10.1107/S0108270109003278 . Acta Crystallographica. Section C: Crystal Structure Communications
CYP17 Inhibitors for Prostate Cancer Treatment – An Update
Moreira, V.; Salvador, J.; Vasaitis, T.; Njar, V., Current Medicinal Chemistry. 868 - 899. 9. 15. 2008. http://dx.doi.org/10.2174/092986708783955428 . 10.2174/092986708783955428 . Current Medicinal Chemistry
Synthesis of novel C17 steroidal carbamates. Studies on CYP17 action, androgen receptor binding and function, and prostate cancer cell growth
Vânia M Moreira; Tadas S. Vasaitis; Zhiyong Guo; Vincent C. O. Njar; Jorge A. R. Salvador, Steroids. 1217 - 1227. 73. 2008. https://doi.org/10.1016/j.steroids.2008.05.010 . Steroids
1H-and 2H-indazole derivatives of androsta-5,16-dien-3ß-ol
Manuela R. Silva; Vânia M Moreira; Cláudia Cardoso; Ana M. Beja; Jorge A. R. Salvador, Acta Crystallographica. Section C: Crystal Structure Communications. o217 - o219. C64. 2008. https://doi.org/10.1107/S0108270108005842 . Acta Crystallographica. Section C: Crystal Structure Communications
Conformation of 17-Chloro-16-formylandrosta-5,16-dien-3ß-yl acetate and 17-chloroandrosta-5,16-dien-3ß-yl acetate
Manuela R. Silva; Vânia M Moreira; Cláudia Cardoso; Ana Matos Beja; Jorge A. R. Salvador, Acta Crystallographica. Section C: Crystal Structure Communications. o529 - o531. C64. 2008. https://doi.org/10.1107/S0108270108025997 . Acta Crystallographica. Section C: Crystal Structure Communications
Catalytic Epoxidation and syn-Dihydroxylation Reactions in Steroid Chemistry
Jorge A. R. Salvador; Samuel M. Silvestre; Vânia M Moreira, Current Organic Chemistry. 492 - 522. 12. 2008. https://doi.org/10.2174/138527208784083897 . Current Organic Chemistry
3-Oxoandrost-4-en-17ß-yl 1H-imidazole-1-carboxylate
Ramos Silva, Manuela; Matos Beja, Ana; Moreira, Vânia M.; Santos, Rita C.; Salvador, Jorge A. R., Acta Crystallographica Section E Structure Reports Online. o4824 - o4824. 12. 63. 2007. http://dx.doi.org/10.1107/s1600536807057625 . 10.1107/s1600536807057625 . Acta Crystallographica Section E Structure Reports Online
Synthesis and evaluation of novel 17-indazole androstene derivatives designed as CYP17 inhibitors
Vânia M Moreira; Tadas S Vasaitis; Vincent C. O. Njar; Jorge A. R. Salvador, Steroids. 939 - 948. 72. 2007. https://doi.org/10.1016/j.steroids.2007.08.004 . Steroids
Catalytic oxidative processes in steroid chemistry: allylic oxidation, ß-selective epoxidation, alcohol oxidations and remote functionalization reactions
Jorge A. R. Salvador; Samuel M. Silvestre; Vânia M Moreira, Current Organic Chemistry. 2227 - 2257. 10. 2006. https://doi.org/10.2174/138527206778742641 . Current Organic Chemistry
One-pot, high yield synthesis of a-ketols from delta5-steroids
Jorge A. R. Salvador; Vânia M Moreira; James R. Hanson; Rui A. Carvalho, Steroids. 266 - 272. 71. 2005. https://doi.org/10.1016/j.steroids.2005.11.002 . Steroids
5 43 out of 43 Publications
All projects
Information of exclusive responsibility of the researcher 01-12-2024 , from platform CIÊNCIAVITAE.
2022/10 - 2023/09
Polímeros naturais biodegradáveis para filmes antimicrobianos e biocompatíveis (PHAsFilm )
IT0179.01 – INOV-C+
Co-Principal Investigator (Co-PI)
Funders: Universidade de Coimbra
2021/01/01 - 2025/12/31
Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
LA/P/0058/2020
Universidade de Coimbra
Funders: Fundação para a Ciência e a Tecnologia
2019/02 - 2021/08
Diterpenoid-based scaffolds for enabling skin repair (DipSkinRepair)
S18-23
Principal investigator
Funders: Tenovus Scotland
2018/10 - 2021/09
Doctoral Training Partnership 2018-19 - Next generation bio-based antimicrobial agents
GEN1227-226
Principal investigator
Funders: Engineering and Physical Sciences Research Council
2017/09 - 2019/09
Chancellor's Research Fellow (Start-up funds)
GEN1227-201
Principal investigator
Funders: University of Strathclyde
2016/09 - 2018/01
Sustainable hydrophobic materials for antimicrobial coatings (RESICELL)
1297/31/2016
Principal investigator
Funders: Business Finland
2015 - 2016
Fully renewable bioactive textiles II
WBS4704219
Principal investigator
Funders: Huonekalusäätio
2014/05 - 2018/04
Synthesis of novel abietane-type diterpenoids with anticancer activity (doctoral scholarships)
264020
Principal investigator
Funders: Helsingin Yliopisto
2014 - 2015
Fully renewable bioactive textiles
WBS4703795
Principal investigator
Funders: Huonekalusäätio
2013 - 2014
Synthesis of Oxamniquine Derivatives for Cancer Treatment. A Drug Repositioning Approach
WBS4703311
Researcher
Funders: Magnus Ehrnroothin Säätiö
2013/01 - 2015/12
Wood diterpenes as leads to new anti-biofilm strategies (WOODYFILM)
decision 264020
Researcher
Funders: Suomen Akatemia
2013/11 - 2018/10
Understanding chronic pain and new druggable targets: Focus on glial-opioid receptor interface (GLORIA)
602919
Researcher
Funders: Seventh Framework Programme
2012/05 - 2013/04
Design, synthesis and biological evaluation of new diterpenoids with potential for the treatment of cancer
ME2012n44
Principal investigator
Funders: Magnus Ehrnroothin Säätiö
2011/01/01 - 2013/12/31
Projecto Estratégico - UI 313 - 2011-2012
PEst-C/QUI/UI0313/2011
Universidade de Coimbra
Funders: Fundação para a Ciência e a Tecnologia
2011/09 - 2015/12
Betulins, abietanes and resin acids as novel lead compounds for cancer (BARC)
decision 252308
Researcher
Funders: Suomen Akatemia
2011/06 - 2014/05
FuBio Joint Research 2
Future Biorefinery - FuBio Joint Research 2
Researcher
Funders: Business Finland
2009/04 - 2012/03
PREPARAÇÃO E AVALIAÇÃO PRÉ-CLÍNICA DE NOVOS COMPOSTOS BORADOS COMO POTENCIAIS AGENTES ANTITUMORAIS
Provided by PTCRIS: SFRH/BPD/45037/2008
Post-doc Fellow
Funders: Fundação para a Ciência e a Tecnologia
2003/12 - 2007/11
NOVOS ESTERÓIDES INIBIDORES DA BIOSSÍNTESE DE ANDROGÉNEOS
Provided by PTCRIS: SFRH/BD/12508/2003
PhD Student Fellow
Funders: Fundação para a Ciência e a Tecnologia
5 18 out of 18 projects
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