Vilma Sardão

Mitochondria dysfunction induced by decyl-TPP mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 sensitizes cisplatin lung anticancer therapy due to a remodeling of energy metabolism

Amorim, Ricardo; Magalhães, Carina C.; Benfeito, Sofia; Cagide, Fernando; Tavares, Ludgero C.; Santos, Katia; Sardão, Vilma A.; et al, Biochemical Pharmacology. 219. 2024. http://dx.doi.org/10.1016/j.bcp.2023.115953 . 10.1016/j.bcp.2023.115953 . Biochemical Pharmacology

Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCd Activator

Cláudia Bessa; Joana B. Loureiro; Matilde Barros; Vera M. S. Isca; Vilma A. Sardão; Paulo J. Oliveira; Raquel L. Bernardino; et al, International Journal of Molecular Sciences. 2023. https://doi.org/10.3390/ijms24065710 . 10.3390/ijms24065710 . International Journal of Molecular Sciences

Brassica oleracea Var italica by-Products Prevent Lipid Accumulation and Cell Death in a Liver Cell Model of Lipid Toxicity

José P. Castelão-Baptista; Sara A. Valente; Sara Canário; David Oppolzer; Ana Barros; Carlos Venâncio; Tânia Martins; et al, Nutrients. 2023. https://doi.org/10.3390/nu15040924 . 10.3390/nu15040924 . Nutrients

Integrative Profiling of Amyotrophic Lateral Sclerosis Lymphoblasts Identifies Unique Metabolic and Mitochondrial Disease Fingerprints

Cunha-Oliveira, T.; Carvalho, M.; Sardão, V.; Ferreiro, E.; Mena, D.; Pereira, F.B.; Borges, F.; et al, Molecular Neurobiology. 6373 - 6396. 10. 59. 2022. http://www.scopus.com/inward/record.url?eid=2-s2.0-85135617163&partnerID=MN8TOARS . 10.1007/s12035-022-02980-7 . submitted Molecular Neurobiology

The Impact of Moderate-to-High-Intensity Exercise Protocols on Glycated Hemoglobin Levels in Type 2 Diabetes Patients

Ana Pedrosa; Guilherme Furtado; Marcelo Paes de Barros; André Luís Lacerda Bachi; José Pedro Ferreira; Vilma A. Sardão; Luís Rama; Ana Teixeira, Diabetology. 2022. https://doi.org/10.3390/diabetology4010002 . 10.3390/diabetology4010002 . Diabetology

1,8-cineole Ameliorates Right Ventricle Dysfunction Associated With Pulmonary Arterial Hypertension by Restoring Connexin 43 and Mitochondrial Homeostasis

Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana, Sofia; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al, Pharmacological Research. 2022. http://dx.doi.org/10.1016/j.phrs.2022.106151 . 10.1016/j.phrs.2022.106151 . Pharmacological Research

Glutaminolysis is a metabolic route essential for survival and growth of prostate cancer cells and a target of 5a-dihydrotestosterone regulation

Cardoso, Henrique J.; Figueira, Marília I.; Vaz, Cátia V.; Carvalho, Tiago M. A.; Brás, Luís A.; Madureira, Patrícia A.; Oliveira, Paulo J.; Sardão, Vilma; Socorro, Sílvia, Cellular Oncology. 2021. http://dx.doi.org/10.1007/s13402-020-00575-9 . 10.1007/s13402-020-00575-9 . Cellular Oncology

Sustaining efficient immune functions with regular physical exercise in the COVID-19 era and beyond

Guilherme Eustáquio Furtado; Rubens Vinícius Letieri; Adriana Caldo; Vilma Sardão; Ana Maria Teixeira; Marcelo Paes de Barros; Rodolfo Paula Vieira; André Luís Lacerda Bachi, European Journal of Clinical Investigation. 2021. https://doi.org/10.1111/eci.13485 . 10.1111/eci.13485 . European Journal of Clinical Investigation

The mitochondrial permeability transition pore: an evolving concept critical for cell life and death

Giampaolo Morciano; Natalia Naumova; Piotr Koprowski; Sara Valente; Vilma A. Sardão; Yaiza Potes; Alessandro Rimessi; Mariusz R. Wieckowski; Paulo J. Oliveira, Biological Reviews. 2021. https://doi.org/10.1111/brv.12764 . 10.1111/brv.12764 . Biological Reviews

The advantages of physical exercise as a preventive strategy against NAFLD in Postmenopausal Women

Emilio Molina-Molina; Guilherme E. Furtado; John G. Jones; Piero Portincasa; Ana Vieira-Pedrosa; Ana Maria Teixeira; Marcelo P. Barros; André L. Bachi; Vilma A. Sardão, European Journal of Clinical Investigation. 2021. https://doi.org/10.1111/eci.13731 . 10.1111/eci.13731 . European Journal of Clinical Investigation

Three in One: The Potential of Brassica By-Products against Economic Waste, Environmental Hazard, and Metabolic Disruption in Obesity

José P. Castelão-Baptista; A.I.R.N.A.Barros; Tânia Martins; Eduardo Rosa; Vilma A. Sardão, Nutrients. 2021. https://www.mdpi.com/2072-6643/13/12/4194 . 10.3390/nu13124194 . Nutrients

Carbon Monoxide-Neuroglobin Axis Targeting Metabolism Against Inflammation in BV-2 Microglial Cells

Dias-Pedroso, Daniela; Ramalho, José S.; Sardão, Vilma A.; Jones, John G.; Romão, Carlos C.; Oliveira, Paulo J.; Vieira, Helena L.A., Molecular Neurobiology. 2021. http://dx.doi.org/10.1007/s12035-021-02630-4 . 10.1007/s12035-021-02630-4 . Molecular Neurobiology

Afrostyrax lepidophyllus Mildbr. and Monodora myristica (Gaertn.) Dunal Extracts Decrease Doxorubicin Cytotoxicity on H9c2 Cardiomyoblasts

Bruno M. Moukette; José P. Castelão-Baptista; Luciana Ferreira; Ana M. Silva; Rui F. Simões; Célia Cabral; Constant A. Pieme; et al, Evidence-Based Complementary and Alternative Medicine. 2021. https://doi.org/10.1155/2021/8858165 . 10.1155/2021/8858165 . Evidence-Based Complementary and Alternative Medicine

Maternal obesity in sheep impairs foetal hepatic mitochondrial respiratory chain capacity

Serafim, Teresa L.; Cunha-Oliveira, Teresa; Deus, Claudia M.; Sardão, Vilma A.; Cardoso, Ines M.; Yang, Shanshan; Odhiambo, John F.; et al, European Journal of Clinical Investigation. 2020. http://dx.doi.org/10.1111/eci.13375 . 10.1111/eci.13375 . European Journal of Clinical Investigation

P-cadherin induces anoikis-resistance of matrix-detached breast cancer cells by promoting pentose phosphate pathway and decreasing oxidative stress

Sousa, Bárbara; Pereira, Joana; Marques, Ricardo; Grilo, Luís F.; Pereira, Susana P.; Sardão, Vilma A.; Schmitt, Fernando; Oliveira, Paulo J.; Paredes, Joana, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 12. 1866. 2020. http://dx.doi.org/10.1016/j.bbadis.2020.165964 . 10.1016/j.bbadis.2020.165964 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors

Kim, Ha-Neui; Ponte, Filipa; Nookaew, Intawat; Ucer Ozgurel, Serra; Marques-Carvalho, Adriana; Iyer, Srividhya; Warren, Aaron; et al, Scientific Reports. 1. 10. 2020. http://dx.doi.org/10.1038/s41598-020-68890-7 . 10.1038/s41598-020-68890-7 . published Scientific Reports

Mitochondrial Determinants of Doxorubicin-Induced Cardiomyopathy

Wallace, Kendall B.; Sardão, Vilma A.; Oliveira, Paulo J., Circulation Research. 926 - 941. 7. 126. 2020. http://dx.doi.org/10.1161/circresaha.119.314681 . 10.1161/circresaha.119.314681 . Circulation Research

Urine-Derived Stem Cells: Applications in Regenerative and Predictive Medicine

Bento, Guida; Shafigullina, Aygul K.; Rizvanov, Albert A.; Sardão, Vilma A.; Macedo, Maria Paula; Oliveira, Paulo J., Cells. 3. 9. 2020. http://dx.doi.org/10.3390/cells9030573 . 10.3390/cells9030573 . Cells

Cell-based assays as an alternative for the study of aquatic toxicity of pharmaceuticals

Rodrigues, Elsa T.; Varela, Ana T.; Pardal, Miguel A.; Sardão, Vilma A., Environmental Science and Pollution Research. 2019. http://dx.doi.org/10.1007/s11356-019-07384-0 . 10.1007/s11356-019-07384-0 . Environmental Science and Pollution Research

A Mitochondrial Approach to Cardiovascular Risk and Disease

Veloso, Caroline D.; Belew, Getachew D.; Ferreira, Luciana L.; Grilo, Luís F.; Jones, John G.; Portincasa, Piero; Sardão, Vilma A.; Oliveira, Paulo J., Current Pharmaceutical Design. 3175 - 3194. 29. 25. 2019. http://dx.doi.org/10.2174/1389203720666190830163735 . 10.2174/1389203720666190830163735 . Current Pharmaceutical Design

Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells

Bajzikova, Martina; Kovarova, Jaromira; Coelho, Ana R.; Boukalova, Stepana; Oh, Sehyun; Rohlenova, Katerina; Svec, David; et al, Cell Metabolism. 399 - 416.e10. 2. 29. 2019. http://dx.doi.org/10.1016/j.cmet.2018.10.014 . 10.1016/j.cmet.2018.10.014 . Cell Metabolism

Excess fructose and fatty acids trigger a model of non-alcoholic fatty liver disease progression in vitro: Protective effect of the flavonoid silybin

Grasselli, Elena; Baldini, Francesca; Vecchione, Giulia; Oliveira, Paulo; Sard¿o, Vilma; Voci, Adriana; Portincasa, Piero; Vergani, Laura, International Journal of Molecular Medicine. 2019. http://dx.doi.org/10.3892/ijmm.2019.4234 . 10.3892/ijmm.2019.4234 . International Journal of Molecular Medicine

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases

Giorgi, Carlotta; Marchi, Saverio; Simoes, Ines C.M.; Ren, Ziyu; Morciano, Giampaolo; Perrone, Mariasole; Patalas-Krawczyk, Paulina; et al, International Review of Cell and Molecular Biology. 209 - 344. 340. 2018. http://dx.doi.org/10.1016/bs.ircmb.2018.05.006 . 10.1016/bs.ircmb.2018.05.006 . published International Review of Cell and Molecular Biology

Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative.

Teixeira, Jose; Amorim, Ricardo; Santos, Katia; Soares, Pedro; Datta, Sandipan; Cortopassi, Gino A; Serafim, Teresa L; et al, Toxicology. 123 - 139. 393. 2018. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:29141199&KeyUID=MEDLINE:29141199 . 10.1016/j.tox.2017.11.014 . Toxicology

Modulation of mitochondrial dysfunction-related oxidative stress in fibroblasts of patients with Leigh syndrome by inhibition of prooxidative p66Shc pathway

Wojtala, Aleksandra; Karkucinska-Wieckowska, Agnieszka; Sardao, Vilma A.; Szczepanowska, Joanna; Kowalski, Pawel; Pronicki, Maciej; Duszynski, Jerzy; Wieckowski, Mariusz R., Mitochondrion. 62 - 79. 37. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000416296000008&KeyUID=WOS:000416296000008 . 10.1016/j.mito.2017.07.002 . Mitochondrion

The Nutraceutic Silybin Counteracts Excess Lipid Accumulation and Ongoing Oxidative Stress in an In Vitro Model of Non-Alcoholic Fatty Liver Disease Progression

Vecchione, Giulia; Grasselli, Elena; Cioffi, Federica; Baldini, Francesca; Oliveira, Paulo J.; Sardao, Vilma A.; Cortese, Katia; et al, Frontiers in Nutrition. 4. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000411196400001&KeyUID=WOS:000411196400001 . 10.3389/fnut.2017.00042 . Frontiers in Nutrition

Phytoestrogen coumestrol improves mitochondrial activity and decreases oxidative stress in the brain of ovariectomized Wistar-Han rats

Moreira, Ana C.; Silva, Ana M.; Branco, Ana F.; Baldeiras, Ines; Peteira, Goncalo C.; Seica, Raquel; Santos, Maria S.; Sardao, Vilma A., Journal of Functional Foods. 329 - 339. 34. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000403383800036&KeyUID=WOS:000403383800036 . 10.1016/j.jff.2017.05.002 . Journal of Functional Foods

Ketogenic diets: from cancer to mitochondrial diseases and beyond

Branco, Ana F.; Ferreira, André; Simões, Rui F.; Magalhães-Novais, Sílvia; Zehowski, Cheryl; Cope, Elisabeth; Silva, Ana Marta; et al, European Journal of Clinical Investigation. 285 - 298. 3. 46. 2016. http://dx.doi.org/10.1111/eci.12591 . 10.1111/eci.12591 . published European Journal of Clinical Investigation

Sirtuin 1-dependent resveratrol cytotoxicity and pro-differentiation activity on breast cancer cells

Deus, C.M.; Serafim, T.L.; Magalhães-Novais, S.; Vilaça, A.; Moreira, A.C.; Sardão, V.A.; Cardoso, S.M.; Oliveira, P.J., Archives of Toxicology. 1 - 18. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84976428138&partnerID=MN8TOARS . 10.1007/s00204-016-1784-x . Archives of Toxicology

Back to the future: Transgenerational transmission of xenobiotic-induced epigenetic remodeling

Jiménez-Chillarón, J.C.; Nijland, M.J.; Ascensão, A.A.; Sardão, V.A.; Magalhães, J.; Hitchler, M.J.; Domann, F.E.; Oliveira, P.J., Epigenetics. 259 - 273. 4. 10. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84927770406&partnerID=MN8TOARS . 10.1080/15592294.2015.1020267 . Epigenetics

Role of mtDNA-related mitoepigenetic phenomena in cancer

Ferreira, A.; Serafim, T.L.; Sardão, V.A.; Cunha-Oliveira, T., European Journal of Clinical Investigation. 44 - 49. s1. 45. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84919393955&partnerID=MN8TOARS . 10.1111/eci.12359 . European Journal of Clinical Investigation

ß-adrenergic over-stimulation and cardio-myocyte apoptosis: Two receptors, one organelle, two fates?

Branco, A.F.; Moreira, A.C.; Cunha-Oliveira, T.; Couto, R.; Sardão, V.A.; Rizvanov, A.A.; Palotás, A.; Oliveira, P.J., Current Drug Targets. 956 - 964. 10. 15. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925936688&partnerID=MN8TOARS . Current Drug Targets

Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts

Moreira, A.C.; Branco, A.F.; Sampaio, S.F.; Cunha-Oliveira, T.; Martins, T.R.; Holy, J.; Oliveira, P.J.; Sardão, V.A., Biochimica et Biophysica Acta - Molecular Basis of Disease. 2468 - 2478. 12. 1842. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84910051188&partnerID=MN8TOARS . 10.1016/j.bbadis.2014.09.015 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Phytoestrogens as alternative hormone replacement therapy in menopause: What is real, what is unknown

Moreira, A.C.; Silva, A.M.; Santos, M.S.; Sardão, V.A., Journal of Steroid Biochemistry and Molecular Biology. 61 - 71. 143. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896338551&partnerID=MN8TOARS . 10.1016/j.jsbmb.2014.01.016 . Journal of Steroid Biochemistry and Molecular Biology

Mitochondrial and liver oxidative stress alterations induced by N-butyl-N-(4-hydroxybutyl)nitrosamine: Relevance for hepatotoxicity

Oliveira, M.M.; Teixeira, J.C.; Vasconcelos-Nóbrega, C.; Felix, L.M.; Sardão, V.A.; Colaço, A.A.; Oliveira, P.A.; Peixoto, F.P., Journal of Applied Toxicology. 434 - 443. 6. 33. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876712347&partnerID=MN8TOARS . 10.1002/jat.1763 . Journal of Applied Toxicology

Mitochondrial disruption occurs downstream from ß-adrenergic overactivation by isoproterenol in differentiated, but not undifferentiated H9c2 cardiomyoblasts: Differential activation of stress and survival pathways

Branco, A.F.; Sampaio, S.F.; Wieckowski, M.R.; Sardão, V.A.; Oliveira, P.J., International Journal of Biochemistry and Cell Biology. 2379 - 2391. 11. 45. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883513016&partnerID=MN8TOARS . 10.1016/j.biocel.2013.08.006 . International Journal of Biochemistry and Cell Biology

Resveratrol affects differently rat liver and brain mitochondrial bioenergetics and oxidative stress in vitro: Investigation of the role of gender

Moreira, A.C.; Silva, A.M.; Santos, M.S.; Sardão, V.A., Food and Chemical Toxicology. 18 - 26. 53. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871464946&partnerID=MN8TOARS . 10.1016/j.fct.2012.11.031 . Food and Chemical Toxicology

Differentiation-dependent doxorubicin toxicity on h9c2 cardiomyoblasts

Branco, A.F.; Sampaio, S.F.; Moreira, A.C.; Holy, J.; Wallace, K.B.; Baldeiras, I.; Oliveira, P.J.; Sardão, V.A., Cardiovascular Toxicology. 326 - 340. 4. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870546889&partnerID=MN8TOARS . 10.1007/s12012-012-9177-8 . Cardiovascular Toxicology

Measuring reciprocal regulation of mesenchymal stem cell and tumor cell motility in two and three dimensions in vitro

Sardão, V.; Rose-Hellekant, T.; Perkins, E.; Greene, A.; Holy, J., Stem Cell Research Journal. 281 - 305. 4. 3. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879738670&partnerID=MN8TOARS . Stem Cell Research Journal

Isoproterenol Cytotoxicity is Dependent on the Differentiation State of the Cardiomyoblast H9c2 Cell Line

Branco, Ana F.; Pereira, Sandro L.; Moreira, Ana C.; Holy, Jon; Sardão, Vilma A.; Oliveira, Paulo J., Cardiovascular Toxicology. 191 - 203. 3. 11. 2011. http://dx.doi.org/10.1007/s12012-011-9111-5 . 10.1007/s12012-011-9111-5 . Cardiovascular Toxicology

Metabolic remodeling during H9c2 myoblast differentiation: Relevance for in vitro toxicity studies

Pereira, S.L.; Ramalho-Santos, J.; Branco, A.F.; Sardão, V.A.; Oliveira, P.J.; Carvalho, R.A., Cardiovascular Toxicology. 180 - 190. 2. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958056642&partnerID=MN8TOARS . 10.1007/s12012-011-9112-4 . Cardiovascular Toxicology

Erratum: Isoproterenol cytotoxicity is dependent on the differentiation state of the cardiomyoblast H9c2 cell line (Cardiovascular Toxicology DOI: 10.1007/s12012-011-9111-5)

Branco, A.F.; Pereira, S.L.; Moreira, A.C.; Holy, J.; Sardão, V.A.; Oliveira, P.J., Cardiovascular Toxicology. 3. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054890288&partnerID=MN8TOARS . 10.1007/s12012-011-9131-1 . Cardiovascular Toxicology

Anti-apoptotic protection afforded by cardioplegic celsior and histidine buffer solutions to hearts subjected to ischemia and ischemia/reperfusion

Alves, M.G.; MacHado, N.G.; Sardão, V.A.; Carvalho, R.A.; Oliveira, P.J., Journal of Cellular Biochemistry. 3872 - 3881. 12. 112. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80055000219&partnerID=MN8TOARS . 10.1002/jcb.23320 . Journal of Cellular Biochemistry

Acute exercise protects against calcium-induced cardiac mitochondrial permeability transition pore opening in doxorubicin-treated rats

Ascensão, A.; Lumini-Oliveira, J.; Machado, N.G.; Ferreira, R.M.; Gonçalves, I.O.; Moreira, A.C.; Marques, F.; et al, Clinical Science. 37 - 49. 1. 120. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650871083&partnerID=MN8TOARS . 10.1042/CS20100254 . Clinical Science

Erratum: Nitrogen compounds prevent H9c2 myoblast oxidative stress-induced mitochondrial dysfunction and cell death (Cardiovascular Toxicology (2010) 10 (51-65) DOI:10.1007/s12012-010-9062-2)

Silva, J.P.; Sardão, V.A.; Coutinho, O.P.; Oliveira, P.J., Cardiovascular Toxicology. 2. 10. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956395509&partnerID=MN8TOARS . 10.1007/s12012-010-9067-x . Cardiovascular Toxicology

Nitrogen compounds prevent H9c2 myoblast oxidative stress-induced mitochondrial dysfunction and cell death

Silva, J.P.; Sardão, V.A.; Coutinho, O.P.; Olveira, P.J., Cardiovascular Toxicology. 51 - 65. 1. 10. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77951143286&partnerID=MN8TOARS . 10.1007/s12012-010-9062-2 . Cardiovascular Toxicology

Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts

Sardão, V.A.; Oliveira, P.J.; Holy, J.; Oliveira, C.R.; Wallace, K.B., Cancer Chemotherapy and Pharmacology. 811 - 827. 4. 64. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-68149169047&partnerID=MN8TOARS . 10.1007/s00280-009-0932-x . Cancer Chemotherapy and Pharmacology

Investigating drug-induced mitochondrial toxicity: A biosensor to increase drug safety?

Pereira, C.V.; Moreira, A.C.; Pereira, S.P.; Machado, N.G.; Carvalho, F.S.; Sardão, V.A.; Oliveira, P.J., Current Drug Safety. 34 - 54. 1. 4. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-63249131066&partnerID=MN8TOARS . 10.2174/157488609787354440 . Current Drug Safety

Morphological alterations induced by doxorubicin on H9c2 myoblasts: Nuclear, mitochondrial, and cytoskeletal targets

Sardão, V.A.; Oliveira, P.J.; Holy, J.; Oliveira, C.R.; Wallace, K.B., Cell Biology and Toxicology. 227 - 243. 3. 25. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349167673&partnerID=MN8TOARS . 10.1007/s10565-008-9070-1 . Cell Biology and Toxicology

Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line

Serafim, T.L.; Oliveira, P.J.; Sardao, V.A.; Perkins, E.; Parke, D.; Holy, J., Cancer Chemotherapy and Pharmacology. 1007 - 1018. 6. 61. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-41049098849&partnerID=MN8TOARS . 10.1007/s00280-007-0558-9 . Cancer Chemotherapy and Pharmacology

Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells-Nuclear vs. mitochondrial effects

Serafim, T.L.; Matos, J.A.C.; Sardão, V.A.; Pereira, G.C.; Branco, A.F.; Pereira, S.L.; Parke, D.; et al, Biochemical Pharmacology. 1459 - 1475. 11. 76. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-55949119796&partnerID=MN8TOARS . 10.1016/j.bcp.2008.07.013 . Biochemical Pharmacology

Drug-induced mitochondrial dysfunction in cardiac and skeletal muscle injury

Sardão, V.A.; Pereira, S.L.; Oliveira, P.J., Expert Opinion on Drug Safety. 129 - 146. 2. 7. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-41349119625&partnerID=MN8TOARS . 10.1517/14740338.7.2.129 . Expert Opinion on Drug Safety

Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide - Characterization of morphological features of cell death

Sardão, V.A.; Oliveira, P.J.; Holy, J.; Oliveira, C.R.; Wallace, K.B., BMC Cell Biology. 8. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947598915&partnerID=MN8TOARS . 10.1186/1471-2121-8-11 . BMC Cell Biology

Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: Comparison with direct effects on isolated mitochondrial fractions

Pereira, G.C.; Branco, A.F.; Matos, J.A.C.; Pereira, S.L.; Parke, D.; Perkins, E.L.; Serafim, T.L.; et al, Journal of Pharmacology and Experimental Therapeutics. 636 - 649. 2. 323. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35548974344&partnerID=MN8TOARS . 10.1124/jpet.107.128017 . Journal of Pharmacology and Experimental Therapeutics

Pt(II) vs Pd(II) polyamine complexes as new anticancer drugs: A structure-activity study

Fiuza, S.M.; Amado, A.M.; Oliveira, P.J.; Sardão, V.A.; Batista De Carvalho, L.A.E.; Marques, M.P.M., Letters in Drug Design and Discovery. 149 - 151. 3. 3. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645876182&partnerID=MN8TOARS . 10.2174/157018006776286989 . Letters in Drug Design and Discovery

Bile acids are toxic for isolated cardiac mitochondria: A possible cause for hepatic-derived cardiomyopathies?

Ferreira, M.; Coxito, P.M.; Sardão, V.A.; Palmeira, C.M.; Oliveira, P.J., Cardiovascular Toxicology. 63 - 73. 1. 5. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-18544374442&partnerID=MN8TOARS . Cardiovascular Toxicology

Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats

Oliveira, P.J.; Seica, R.; Santos, D.L.; Rolo, A.P.; Sardao, V.A.; Ferreira, F.M.L.; Palmeira, C.M.; Santos, M.S.; Moreno, A.J.M., Mitochondrion. 337 - 345. 6. 3. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942484378&partnerID=MN8TOARS . 10.1016/j.mito.2004.02.005 . Mitochondrion

Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function

Oliveira, P.J.; Rolo, A.P.; Sardão, V.A.; Monteiro, P.; Gonçalves, L.; Providência, L.A.; Palmeira, C.M.; Moreno, A.J.M., Revista Portuguesa de Cardiologia. 1291 - 1298. 10. 23. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-10644236410&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Caffeine enhances the calcium-dependent cardiac mitochondrial permeability transition: Relevance for caffeine toxicity

Sardão, V.A.; Oliveira, P.J.; Moreno, A.J.M., Toxicology and Applied Pharmacology. 50 - 56. 1. 179. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037082662&partnerID=MN8TOARS . 10.1006/taap.2001.9334 . Toxicology and Applied Pharmacology

Impact of diabetes on induction of the mitochondrial permeability transition.

Oliveira, P.J.; Rolo, A.P.; Seiça, R.; Sardão, V.; Monteiro, P.; Gonçalves, L.; Providência, L.; et al, Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 759 - 766. 6. 21. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036616238&partnerID=MN8TOARS . Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Carvedilol in heart mitochondria - Protonophore or opener of the mitochondrial KATP channels?

Oliveira, P.J.; Rolo, A.P.; Sardão, V.A.; Coxito, P.M.; Palmeira, C.M.; Moreno, A.J.M., Life Sciences. 123 - 132. 2. 69. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035371154&partnerID=MN8TOARS . 10.1016/S0024-3205(01)01109-2 . Life Sciences