Neuroscience and Disease
Biomarkers in Neuropsychiatric Disorders: from Molecules to Diagnosis and Intervention
Neurological Diseases
Neuropsychiatric Diseases
Diagnosis
Biomarkers
Neurological Diseases
Neuropsychiatric Diseases
Diagnosis
Biomarkers
Neuropsychiatric disorders have a huge impact at an individual and society level, posing a tremendous amount of psychological, financial, academic, and social burden, which reinforces the importance of early diagnosis and intervention. Our main goal is the identification of new biomarkers, focused on neuropsychiatric disorders, leading to the design of patient-tailored preventive and therapeutic interventions, promoting the translation to the clinic of fundamental research. The research developed in the group relies on collaborative efforts between fundamental researchers and clinicians for access to human biological samples and clinical data. The team is integrated in international consortia that define standard methodologies and allow for big-data studies and clinical trials.
As a leading reference in neurodegenerative disorders in Portugal we have focus on identifying early cognitive, imaging and fluid biomarkers with potential application in clinical settings. We contributed to: (i) standardization of the most used screening cognitive tools, memory tests and behavioral scales. (ii) development of advanced imaging biomarkers (3tesla MRI, PET imaging) for dementia, Multiple Sclerosis (MS), Stroke and Delirium; (iii) validate CSF biomarkers for Alzheimer´s disease (AD), Fronto-Temporal Dementia (FTD), Prion diseases and MS, extended more recently to blood biomarkers using both automated and Single Molecule Array (SiMoA) approaches, pioneer in our country and available to large cohorts.
Overall, our work has contributed to a change in the diagnostic and prognostic paradigm of neurodegenerative diseases in Portugal, moving from a strictly clinical perspective towards a biological approach. We have also been involved in dissecting brain alterations in animal models, associated with neuropsychiatric conditions, such as drug abuse, and with neurodevelopmental conditions, including Attention-Deficit/Hyperactivity Disorder (ADHD), with particularly interest in neurometabolic, neuroinflammatory and neurovascular processes. We have also been involved in pinpointing the role of lifestyle including physical exercise as an interventional approach for brain health, at a fundamental level.
Information about journal articles, updated at 17-11-2024, from platform CIÊNCIAVITAE.
Structural MRI predicts clinical progression in presymptomatic genetic frontotemporal dementia: findings from the GENetic Frontotemporal dementia Initiative cohort
Bocchetta, Martina; Todd, Emily G; Bouzigues, Arabella; Cash, David M; Nicholas, Jennifer M; Convery, Rhian S; Russell, Lucy L; et al, 2023. Brain Communications. 2. 5. 2023. http://dx.doi.org/10.1093/braincomms/fcad061 . 10.1093/braincomms/fcad061 . Brain Communications
Montreal Cognitive Assessment in Mild Cognitive Impairment: Relationship with Cerebrospinal Fluid Biomarkers and Conversion to Dementia
Bernardes, Catarina; Lima, Marisa; Duro, Diana; Silva-Spínola, Anuschka; Durães, João; Tábuas-Pereira, Miguel; Baldeiras, Inês; Freitas, Sandra; Santana, Isabel, 2023. Journal of Alzheimer's Disease. 1173 - 1182. 3. 96. 2023. http://dx.doi.org/10.3233/jad-230916 . 10.3233/jad-230916 . Journal of Alzheimer's Disease
Serum Neurofilament Light Chain in the Diagnostic Evaluation of Patients with Cognitive Symptoms in the Neurological Consultation of a Tertiary Center
Lopes das Neves, Pedro; Durães, João; Silva-Spinola, Anuschka; Lima, Marisa; Leitão, Maria João; Tábuas-Pereira, Miguel; Santana, Isabel; Baldeiras, Inês, 2023. Journal of Alzheimer's Disease. 391 - 397. 2. 95. 2023. http://dx.doi.org/10.3233/jad-221208 . 10.3233/jad-221208 . Journal of Alzheimer's Disease
Towards a neurocognitive profile in familial cerebral cavernous malformations
Silva, Cristiana; Durães, João; Lima, Marisa; Pereira, Daniela Jardim; Santana, Isabel; Almeida, Maria Rosário, 2023. Acta Neurologica Belgica. 49 - 54. 1. 124. 2023. http://dx.doi.org/10.1007/s13760-023-02314-x . 10.1007/s13760-023-02314-x . Acta Neurologica Belgica
Population Pharmacokinetic Analysis of Perampanel in Portuguese Patients Diagnosed with Refractory Epilepsy
Silva, Rui; Colom, Helena; Bicker, Joana; Almeida, Anabela; Silva, Ana; Sales, Francisco; Santana, Isabel; Falcão, Amílcar; Fortuna, Ana, 2023. Pharmaceutics. 6. 15. 2023. http://dx.doi.org/10.3390/pharmaceutics15061704 . 10.3390/pharmaceutics15061704 . Pharmaceutics
Prodromal language impairment in genetic frontotemporal dementia within the GENFI cohort
Samra, Kiran; MacDougall, Amy M.; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; et al, 2023. Journal of the Neurological Sciences. 451. 2023. http://dx.doi.org/10.1016/j.jns.2023.120711 . 10.1016/j.jns.2023.120711 . Journal of the Neurological Sciences
Textural properties of microglial activation in Alzheimer’s disease as measured by (R)-[11C]PK11195 PET
Lapo Pais, Marta; Jorge, Lília; Martins, Ricardo; Canário, Nádia; Xavier, Ana Carolina; Bernardes, Rui; Abrunhosa, Antero; Santana, Isabel; Castelo-Branco, Miguel, 2023. Brain Communications. 3. 5. 2023. http://dx.doi.org/10.1093/braincomms/fcad148 . 10.1093/braincomms/fcad148 . Brain Communications
Characterization of Progranulin Gene Mutations in Portuguese Patients with Frontotemporal Dementia
Almeida, Maria Rosário; Tábuas-Pereira, Miguel; Baldeiras, Inês; Lima, Marisa; Durães, João; Massano, João; Pinto, Madalena; Cruto, Catarina; Santana, Isabel, 2023. International Journal of Molecular Sciences. 1. 25. 2023. http://dx.doi.org/10.3390/ijms25010511 . 10.3390/ijms25010511 . International Journal of Molecular Sciences
Genetic forms of primary progressive aphasia within the GENetic Frontotemporal dementia Initiative (GENFI) cohort: comparison with sporadic primary progressive aphasia
Samra, Kiran; MacDougall, Amy M; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M; Greaves, Caroline V; Convery, Rhian S; et al, 2023. Brain Communications. 2. 5. 2023. http://dx.doi.org/10.1093/braincomms/fcad036 . 10.1093/braincomms/fcad036 . Brain Communications
Early neurotransmitters changes in prodromal frontotemporal dementia: A GENFI study
Premi, Enrico; Pengo, Marta; Mattioli, Irene; Cantoni, Valentina; Dukart, Juergen; Gasparotti, Roberto; Buratti, Emanuele; et al, 2023. Neurobiology of Disease. 179. 2023. http://dx.doi.org/10.1016/j.nbd.2023.106068 . 10.1016/j.nbd.2023.106068 . Neurobiology of Disease
Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementia
Bussy, Aurélie; Levy, Jake P.; Best, Tristin; Patel, Raihaan; Cupo, Lani; Van Langenhove, Tim; Nielsen, Jørgen E.; et al, 2023. Human Brain Mapping. 2684 - 2700. 7. 44. 2023. http://dx.doi.org/10.1002/hbm.26220 . 10.1002/hbm.26220 . Human Brain Mapping
Blood biomarkers in mild cognitive impairment patients: Relationship between analytes and progression to Alzheimer disease dementia
Silva-Spínola, Anuschka; Lima, Marisa; Leitão, Maria João; Bernardes, Catarina; Durães, João; Duro, Diana; Tábuas-Pereira, Miguel; Santana, Isabel; Baldeiras, Inês, 2023. European Journal of Neurology. 1565 - 1573. 6. 30. 2023. http://dx.doi.org/10.1111/ene.15762 . 10.1111/ene.15762 . European Journal of Neurology
Reconsidering the role of blood-brain barrier in Alzheimer’s disease: From delivery to target
Sousa, João André; Bernardes, Catarina; Bernardo-Castro, Sara; Lino, Miguel; Albino, Inês; Ferreira, Lino; Brás, José; et al, 2023. Frontiers in Aging Neuroscience. 15. 2023. http://dx.doi.org/10.3389/fnagi.2023.1102809 . 10.3389/fnagi.2023.1102809 . Frontiers in Aging Neuroscience
The Benson Complex Figure Test detects deficits in visuoconstruction and visual memory in symptomatic familial frontotemporal dementia: A GENFI study
Jiskoot, Lize C.; Russell, Lucy L.; Peakman, Georgia; Convery, Rhian S.; Greaves, Caroline V.; Bocchetta, Martina; Poos, Jackie M.; et al, 2023. Journal of the Neurological Sciences. 446. 2023. http://dx.doi.org/10.1016/j.jns.2023.120590 . 10.1016/j.jns.2023.120590 . Journal of the Neurological Sciences
Neuropsychiatric symptoms in genetic frontotemporal dementia: developing a new module for Clinical Rating Scales
Samra, Kiran; Macdougall, Amy; Peakman, Georgia; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M; Greaves, Caroline V; et al, 2023. Journal of Neurology, Neurosurgery & Psychiatry. 357 - 368. 5. 94. 2023. http://dx.doi.org/10.1136/jnnp-2022-330152 . 10.1136/jnnp-2022-330152 . Journal of Neurology, Neurosurgery & Psychiatry
Two Phase 3 Trials of Gantenerumab in Early Alzheimer’s Disease
Bateman, Randall J.; Smith, Janice; Donohue, Michael C.; Delmar, Paul; Abbas, Rachid; Salloway, Stephen; Wojtowicz, Jakub; et al, 2023. New England Journal of Medicine. 1862 - 1876. 20. 389. 2023. http://dx.doi.org/10.1056/nejmoa2304430 . 10.1056/nejmoa2304430 . New England Journal of Medicine
Neuropsychological Assessment in the Distinction Between Biomarker Defined Frontal-Variant of Alzheimer’s Disease and Behavioral-Variant of Frontotemporal Dementia
Lima, Marisa; Tábuas-Pereira, Miguel; Durães, João; Vieira, Daniela; Faustino, Pedro; Baldeiras, Inês; Santana, Isabel, 2023. Journal of Alzheimer's Disease. 1303 - 1312. 4. 91. 2023. http://dx.doi.org/10.3233/jad-220897 . 10.3233/jad-220897 . Journal of Alzheimer's Disease
Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease
Daniela Marinho; Ildete Luísa Ferreira; Ricardo Lorenzoni; Sandra M. Cardoso; Isabel Santana; A. Cristina Rego, 2023. Aging Cell. 2023. https://doi.org/10.1111/acel.13895 . 10.1111/acel.13895 . Aging Cell
Hemispheric Patterns of Recruitment of Object Processing Regions in Early Alzheimer’s Disease: A Study Along the Entire Ventral Stream
Canário, Nádia S.; Jorge, Lília P.; Santana, Isabel J.; Castelo-Branco, Miguel S., 2023. Journal of Alzheimer's Disease. 1151 - 1164. 3. 91. 2023. http://dx.doi.org/10.3233/jad-220055 . 10.3233/jad-220055 . Journal of Alzheimer's Disease
TREX1 p.A129fs and p.Y305C variants in a large multi-ethnic cohort of CADASIL-like unrelated patients
Foddis, Marco; Blumenau, Sonja; Holtgrewe, Manuel; Paquette, Kimberly; Westra, Kaitlyn; Alonso, Isabel; Macario, Maria do Carmo; et al, 2023. Neurobiology of Aging. 208 - 215. 123. 2023. http://dx.doi.org/10.1016/j.neurobiolaging.2022.11.013 . 10.1016/j.neurobiolaging.2022.11.013 . Neurobiology of Aging
Altered plasma protein profiles in genetic FTD – a GENFI study
Ullgren, Abbe; Öijerstedt, Linn; Olofsson, Jennie; Bergström, Sofia; Remnestål, Julia; van Swieten, John C.; Jiskoot, Lize C.; et al, 2023. Molecular Neurodegeneration. 1. 18. 2023. http://dx.doi.org/10.1186/s13024-023-00677-6 . 10.1186/s13024-023-00677-6 . Molecular Neurodegeneration
The Assessment of Cognitive Reserve: A Systematic Review of the Most Used Quantitative Measurement Methods of Cognitive Reserve for Aging
Nogueira, Joana; Gerardo, Bianca; Santana, Isabel; Simões, Mário R.; Freitas, Sandra, 2022. Frontiers in Psychology. 13. 2022. http://dx.doi.org/10.3389/fpsyg.2022.847186 . 10.3389/fpsyg.2022.847186 . published Frontiers in Psychology
Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study
van der Ende, Emma L.; Heller, Carolin; Sogorb-Esteve, Aitana; Swift, Imogen J.; McFall, David; Peakman, Georgia; Bouzigues, Arabella; et al, 2022. Journal of Neuroinflammation. 1. 19. 2022. http://dx.doi.org/10.1186/s12974-022-02573-0 . 10.1186/s12974-022-02573-0 . published Journal of Neuroinflammation
Exome Sequencing of a Portuguese Cohort of Frontotemporal Dementia Patients: Looking Into the ALS-FTD Continuum
Tábuas-Pereira, Miguel; Santana, Isabel; Gibbons, Elizabeth; Paquette, Kimberly; Almeida, Maria Rosário; Baldeiras, Inês; Bras, Jose; Guerreiro, Rita, 2022. Frontiers in Neurology. 13. 2022. http://dx.doi.org/10.3389/fneur.2022.886379 . 10.3389/fneur.2022.886379 . published Frontiers in Neurology
Motor symptoms in genetic frontotemporal dementia: developing a new module for clinical rating scales
Samra, Kiran; MacDougall, Amy M.; Peakman, Georgia; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; et al, 2022. Journal of Neurology. 2022. http://dx.doi.org/10.1007/s00415-022-11442-y . 10.1007/s00415-022-11442-y . published Journal of Neurology
Hierarchical spectral clustering reveals brain size and shape changes in asymptomatic carriers of <i>C9orf72</i>
Bruffaerts, Rose; Gors, Dorothy; Bárcenas Gallardo, Alicia; Vandenbulcke, Mathieu; Van Damme, Philip; Suetens, Paul; van Swieten, John C; et al, 2022. Brain Communications. 4. 4. 2022. http://dx.doi.org/10.1093/braincomms/fcac182 . 10.1093/braincomms/fcac182 . published Brain Communications
Dual PET-fMRI reveals a link between neuroinflammation, amyloid binding and compensatory task-related brain activity in Alzheimer’s disease
Canário, Nádia; Jorge, Lília; Martins, Ricardo; Santana, Isabel; Castelo-Branco, Miguel, 2022. Communications Biology. 1. 5. 2022. http://dx.doi.org/10.1038/s42003-022-03761-7 . 10.1038/s42003-022-03761-7 . published Communications Biology
CSF glial markers are elevated in a subset of patients with genetic frontotemporal dementia
Woollacott, Ione O. C.; Swift, Imogen J.; Sogorb-Esteve, Aitana; Heller, Carolin; Knowles, Kathryn; Bouzigues, Arabella; Russell, Lucy L.; et al, 2022. Annals of Clinical and Translational Neurology. 1764 - 1777. 11. 9. 2022. http://dx.doi.org/10.1002/acn3.51672 . 10.1002/acn3.51672 . published Annals of Clinical and Translational Neurology
Generation and Characterization of Novel iPSC Lines from a Portuguese Family Bearing Heterozygous and Homozygous GRN Mutations
Oliveira, Ana Rafaela; Martins, Solange; Cammarata, Giuseppe; Martins, Mariana; Cardoso, Ana Maria; Almeida, Maria Rosário; do Carmo Macário, Maria; et al, 2022. Biomedicines. 8. 10. 2022. http://dx.doi.org/10.3390/biomedicines10081905 . 10.3390/biomedicines10081905 . published Biomedicines
Clinical Application of Pharmacokinetics to Appraise Adherence to Levetiracetam in Portuguese Epileptic Patients
Silva, Rui; Bicker, Joana; Almeida, Anabela; Carona, Andreia; Silva, Ana; Sales, Francisco; Santana, Isabel; Falcão, Amílcar; Fortuna, Ana, 2022. Biomedicines. 9. 10. 2022. http://dx.doi.org/10.3390/biomedicines10092127 . 10.3390/biomedicines10092127 . published Biomedicines
Lewy body dementia is associated with an increased risk of atrial fibrillation: A case-control study
Tábuas-Pereira, Miguel; Durães, João; Beato-Coelho, José; Rita Nogueira, Ana; Duro, Diana; Baldeiras, Inês; Santana, Isabel, 2022. Journal of Clinical Neuroscience. 62 - 65. 99. 2022. http://dx.doi.org/10.1016/j.jocn.2022.02.038 . 10.1016/j.jocn.2022.02.038 . published Journal of Clinical Neuroscience
Frequency and Longitudinal Course of Motor Signs in Genetic Frontotemporal Dementia
Schönecker, Sonja; Martinez-Murcia, Francisco J.; Rauchmann, Boris-Stephan; Franzmeier, Nicolai; Prix, Catharina; Wlasich, Elisabeth; Loosli, Sandra V.; et al, 2022. Neurology. e1032 - e1044. 10. 99. 2022. http://dx.doi.org/10.1212/wnl.0000000000200828 . 10.1212/wnl.0000000000200828 . published Neurology
Resective Epilepsy Surgery and Respective Histopathological Diagnoses: A Retrospective Cohort Study
Jesus-Ribeiro, Joana; Rebelo, Olinda; Bento, Conceição; Pereira, Cristina; Robalo, Conceição; Rito, Manuel; Pereira, Ricardo; et al, 2022. Acta Médica Portuguesa. 2022. http://dx.doi.org/10.20344/amp.18712 . 10.20344/amp.18712 . published Acta Médica Portuguesa
Examining empathy deficits across familial forms of frontotemporal dementia within the GENFI cohort
Foster, Phoebe H.; Russell, Lucy L.; Peakman, Georgia; Convery, Rhian S.; Bouzigues, Arabella; Greaves, Caroline V.; Bocchetta, Martina; et al, 2022. Cortex. 12 - 28. 150. 2022. http://dx.doi.org/10.1016/j.cortex.2022.01.012 . 10.1016/j.cortex.2022.01.012 . Cortex
In vivo molecular imaging of the neuroinflammatory response to peripheral acute bacterial infection in older patients with cognitive dysfunction: A cross-sectional controlled study
Silva, Ana Rita; Regueira, Patricia; Peres, André; Cardoso, Ana Luísa; Baldeiras, Inês; Santana, Isabel; Cerejeira, Joaquim, 2022. Frontiers in Aging Neuroscience. 14. 2022. http://dx.doi.org/10.3389/fnagi.2022.984178 . 10.3389/fnagi.2022.984178 . published Frontiers in Aging Neuroscience
Corrigendum to “Dissemination in time and space in presymptomatic granulin mutation carriers: A spatial chronnectome study” [Neurobiology of Aging Volume 108, December 2021, Pages 155–167]
Premi, Enrico; Giunta, Marcello; Iraji, Armin; Rachakonda, Srinivas; Calhoun, VinceD.; Gazzina, Stefano; Benussi, Alberto; et al, 2022. Neurobiology of Aging. 140 - 144. 119. 2022. http://dx.doi.org/10.1016/j.neurobiolaging.2022.08.005 . 10.1016/j.neurobiolaging.2022.08.005 . published Neurobiology of Aging
Whole-exome sequencing reveals PSEN1 and ATP7B combined variants as a possible cause of early-onset Lewy body dementia: a case study of genotype–phenotype correlation
Tábuas-Pereira, Miguel; Guerreiro, Rita; Kun-Rodrigues, Célia; Almeida, Maria Rosário; Brás, José; Santana, Isabel, 2022. neurogenetics. 279 - 283. 4. 23. 2022. http://dx.doi.org/10.1007/s10048-022-00699-0 . 10.1007/s10048-022-00699-0 . published neurogenetics
Alzheimer’s Disease Diagnosis Based on the Amyloid, Tau, and Neurodegeneration Scheme (ATN) in a Real-Life Multicenter Cohort of General Neurological Centers
Baldeiras, Inês; Silva-Spínola, Anuschka; Lima, Marisa; Leitão, Maria João; Durães, João; Vieira, Daniela; Tábuas-Pereira, Miguel; et al, 2022. Journal of Alzheimer's Disease. 419 - 432. 1. 90. 2022. http://dx.doi.org/10.3233/jad-220587 . 10.3233/jad-220587 . published Journal of Alzheimer's Disease
Loss of brainstem white matter predicts onset and motor neuron symptoms in C9orf72 expansion carriers: a GENFI study
Pérez-Millan, Agnès; Borrego-Écija, Sergi; van Swieten, John C.; Jiskoot, Lize; Moreno, Fermin; Laforce, Robert; Graff, Caroline; et al, 2022. Journal of Neurology. 2022. http://dx.doi.org/10.1007/s00415-022-11435-x . 10.1007/s00415-022-11435-x . published Journal of Neurology
Cognitive composites for genetic frontotemporal dementia: GENFI-Cog
Poos, Jackie M.; Moore, Katrina M.; Nicholas, Jennifer; Russell, Lucy L.; Peakman, Georgia; Convery, Rhian S.; Jiskoot, Lize C.; et al, 2022. Alzheimer's Research & Therapy. 1. 14. 2022. http://dx.doi.org/10.1186/s13195-022-00958-0 . 10.1186/s13195-022-00958-0 . published Alzheimer's Research & Therapy
An Automated Toolbox to Predict Single Subject Atrophy in Presymptomatic Granulin Mutation Carriers
Premi, Enrico; Costa, Tommaso; Gazzina, Stefano; Benussi, Alberto; Cauda, Franco; Gasparotti, Roberto; Archetti, Silvana; et al, 2022. Journal of Alzheimer's Disease. 1 - 14. 2022. http://dx.doi.org/10.3233/jad-215447 . 10.3233/jad-215447 . published Journal of Alzheimer's Disease
The European Portuguese version of the Oxford Cognitive Screening (OCS-Pt): a screening test for acute stroke patients
Valério, Daniela; Almeida, Jorge; Demeyere, Nele; Lima, Marisa; Nogueira, Joana; Santana, Isabel, 2022. Neurological Sciences. 2022. http://dx.doi.org/10.1007/s10072-022-05880-9 . 10.1007/s10072-022-05880-9 . published Neurological Sciences
Rare variants in TP73 in a frontotemporal dementia cohort link this gene with primary progressive aphasia phenotypes
Tábuas-Pereira, Miguel; Santana, Isabel; Almeida, Maria Rosário; Durães, João; Lima, Marisa; Duro, Diana; Kun-Rodrigues, Célia; Bras, Jose; Guerreiro, Rita, 2022. European Journal of Neurology. 2022. http://dx.doi.org/10.1111/ene.15248 . 10.1111/ene.15248 . published European Journal of Neurology
Data-driven staging of genetic frontotemporal dementia using multi-modal MRI
McCarthy, Jillian; Borroni, Barbara; Sanchez-Valle, Raquel; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthis; et al, 2022. Human Brain Mapping. 2022. http://dx.doi.org/10.1002/hbm.25727 . 10.1002/hbm.25727 . published Human Brain Mapping
Plasma Lipocalin 2 in Alzheimer’s disease: potential utility in the differential diagnosis and relationship with other biomarkers
Hermann, Peter; Villar-Piqué, Anna; Schmitz, Matthias; Schmidt, Christian; Varges, Daniela; Goebel, Stefan; Bunck, Timothy; et al, 2022. Alzheimer's Research & Therapy. 1. 14. 2022. http://dx.doi.org/10.1186/s13195-021-00955-9 . 10.1186/s13195-021-00955-9 . Alzheimer's Research & Therapy
Combined Structural MR and Diffusion Tensor Imaging Classify the Presence of Alzheimer’s Disease With the Same Performance as MR Combined With Amyloid Positron Emission Tomography: A Data Integration Approach
Agostinho, Daniel; Caramelo, Francisco; Moreira, Ana Paula; Santana, Isabel; Abrunhosa, Antero; Castelo-Branco, Miguel, 2022. Frontiers in Neuroscience. 15. 2022. http://dx.doi.org/10.3389/fnins.2021.638175 . 10.3389/fnins.2021.638175 . Frontiers in Neuroscience
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum
Jansen, Willemijn J.; Janssen, Olin; Tijms, Betty M.; Vos, Stephanie J. B.; Ossenkoppele, Rik; Visser, Pieter Jelle; Aarsland, Dag; et al, 2022. JAMA Neurology. 2022. http://dx.doi.org/10.1001/jamaneurol.2021.5216 . 10.1001/jamaneurol.2021.5216 . JAMA Neurology
Anomia is present pre-symptomatically in frontotemporal dementia due to MAPT mutations
Bouzigues, Arabella; Russell, Lucy L.; Peakman, Georgia; Bocchetta, Martina; Greaves, Caroline V.; Convery, Rhian S.; Todd, Emily; et al, 2022. Journal of Neurology. 4322 - 4332. 8. 269. 2022. http://dx.doi.org/10.1007/s00415-022-11068-0 . 10.1007/s00415-022-11068-0 . published Journal of Neurology
Longitudinal Cognitive Changes in Genetic Frontotemporal Dementia Within the GENFI Cohort
Poos, Jackie M.; MacDougall, Amy; van den Berg, Esther; Jiskoot, Lize C.; Papma, Janne M.; van der Ende, Emma L.; Seelaar, Harro; et al, 2022. Neurology. e281 - e295. 3. 99. 2022. http://dx.doi.org/10.1212/wnl.0000000000200384 . 10.1212/wnl.0000000000200384 . published Neurology
Network structure and transcriptomic vulnerability shape atrophy in frontotemporal dementia
Shafiei, Golia; Bazinet, Vincent; Dadar, Mahsa; Manera, Ana L; Collins, D Louis; Dagher, Alain; Borroni, Barbara; et al, 2022. Brain. 2022. http://dx.doi.org/10.1093/brain/awac069 . 10.1093/brain/awac069 . published Brain
Cytogenomic Analysis of Long-Term Epilepsy-Associated Tumors Using an Array-Based CGH Strategy
Jesus-Ribeiro, Joana; Ribeiro, Ilda Patrícia; Pires, Luís Miguel; Paiva, Patrícia; Simões, Sandra; Pereira, Cristina; Robalo, Conceição; et al, 2022. Cytogenetic and Genome Research. 28 - 33. 1-2. 162. 2022. http://dx.doi.org/10.1159/000524130 . 10.1159/000524130 . published Cytogenetic and Genome Research
Serum GFAP differentiates Alzheimer’s disease from frontotemporal dementia and predicts MCI-to-dementia conversion
Oeckl, Patrick; Anderl-Straub, Sarah; Von Arnim, Christine A F; Baldeiras, Inês; Diehl-Schmid, Janine; Grimmer, Timo; Halbgebauer, Steffen; et al, 2022. Journal of Neurology, Neurosurgery & Psychiatry. 659 - 667. 6. 93. 2022. http://dx.doi.org/10.1136/jnnp-2021-328547 . 10.1136/jnnp-2021-328547 . Journal of Neurology, Neurosurgery & Psychiatry
Longitudinal Cognitive Changes in Genetic Frontotemporal Dementia Within the GENFI Cohort
Poos, Jackie M.; MacDougall, Amy; van den Berg, Esther; Jiskoot, Lize C.; Papma, Janne M.; van der Ende, Emma L.; Seelaar, Harro; et al, 2022. Neurology. 3. 99. 2022. http://dx.doi.org/10.1212/wnl.0000000000200384 . 10.1212/wnl.0000000000200384 . Neurology
The landscape of common genetic drivers and <scp>DNA</scp> methylation in low-grade (epilepsy-associated) neuroepithelial tumors: A review
Jesus-Ribeiro, Joana; Rebelo, Olinda; Ribeiro, Ilda Patrícia; Pires, Luís Miguel; Melo, João Daniel; Sales, Francisco; Santana, Isabel; Freire, António; Melo, Joana Barbosa, 2022. Neuropathology. 467 - 482. 6. 42. 2022. http://dx.doi.org/10.1111/neup.12846 . 10.1111/neup.12846 . Neuropathology
Frequency and Longitudinal Course of Motor Signs in Genetic Frontotemporal Dementia
Schönecker, Sonja; Martinez-Murcia, Francisco J.; Rauchmann, Boris-Stephan; Franzmeier, Nicolai; Prix, Catharina; Wlasich, Elisabeth; Loosli, Sandra V.; et al, 2022. Neurology. 10. 99. 2022. http://dx.doi.org/10.1212/wnl.0000000000200828 . 10.1212/wnl.0000000000200828 . Neurology
Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia
Sogorb-Esteve, Aitana; Nilsson, Johanna; Swift, Imogen J.; Heller, Carolin; Bocchetta, Martina; Russell, Lucy L.; Peakman, Georgia; et al, 2022. Alzheimer's Research & Therapy. 1. 14. 2022. http://dx.doi.org/10.1186/s13195-022-01042-3 . 10.1186/s13195-022-01042-3 . Alzheimer's Research & Therapy
Prion-like a-synuclein pathology in the brain of infants with Krabbe disease
Hatton, Christopher; Ghanem, Simona S.; Koss, David J.; Abdi, Ilham Y.; Gibbons, Elizabeth; Guerreiro, Rita; Bras, Jose; et al, 2022. Brain. 1257 - 1263. 4. 145. 2022. http://dx.doi.org/10.1093/brain/awac002 . 10.1093/brain/awac002 . Brain
Peripheral inflammatory markers during an acute bacterial infection in older patients with and without cognitive dysfunction: A case control study
Regueira, Patrícia; Silva, Ana Rita; Cardoso, Ana Luísa; Cardoso, Ana Maria; Baldeiras, Inês; Santana, Isabel; Cerejeira, Joaquim, 2022. Brain, Behavior, & Immunity - Health. 25. 2022. http://dx.doi.org/10.1016/j.bbih.2022.100503 . 10.1016/j.bbih.2022.100503 . Brain, Behavior, & Immunity - Health
Clinical Application of Pharmacokinetics to Appraise Adherence to Levetiracetam in Portuguese Epileptic Patients
Silva, Rui; Bicker, Joana; Almeida, Anabela; Carona, Andreia; Silva, Ana; Sales, Francisco; Santana, Isabel; Falcão, Amílcar; Fortuna, Ana, 2022. Biomedicines. 9. 10. 2022. http://dx.doi.org/10.3390/biomedicines10092127 . 10.3390/biomedicines10092127 . Biomedicines
Temporal dynamics predict symptom onset and cognitive decline in familial frontotemporal dementia
Whiteside, David J.; Malpetti, Maura; Jones, P. Simon; Ghosh, Boyd C. P.; Coyle-Gilchrist, Ian; van Swieten, John C.; Seelaar, Harro; et al, 2022. Alzheimer's & Dementia. 1947 - 1962. 5. 19. 2022. http://dx.doi.org/10.1002/alz.12824 . 10.1002/alz.12824 . Alzheimer's & Dementia
Feasibility of a standard cognitive assessment in European academic memory clinics
Grazia, Alice; Altomare, Daniele; Preis, Lukas; Monsch, Andreas U.; Cappa, Stefano F.; Gauthier, Serge; Frölich, Lutz; et al, 2022. Alzheimer's & Dementia. 2276 - 2286. 6. 19. 2022. http://dx.doi.org/10.1002/alz.12830 . 10.1002/alz.12830 . Alzheimer's & Dementia
Neurodevelopmental effects of genetic frontotemporal dementia in young adult mutation carriers
Finger, Elizabeth; Malik, Rubina; Bocchetta, Martina; Coleman, Kristy; Graff, Caroline; Borroni, Barbara; Masellis, Mario; et al, 2022. Brain. 2120 - 2131. 5. 146. 2022. http://dx.doi.org/10.1093/brain/awac446 . 10.1093/brain/awac446 . Brain
Language impairment in the genetic forms of behavioural variant frontotemporal dementia
Samra, Kiran; MacDougall, Amy M.; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; et al, 2022. Journal of Neurology. 1976 - 1988. 4. 270. 2022. http://dx.doi.org/10.1007/s00415-022-11512-1 . 10.1007/s00415-022-11512-1 . Journal of Neurology
Assessing Older Community Members Using a Social Work Tool: Developing an Organizational Response
Ogrin, Rajna; Meyer, Claudia; Karantzoulis, Aliki; Santana, Isabel Jane; Hampson, Ralph, 2022. Gerontology and Geriatric Medicine. 8. 2022. http://dx.doi.org/10.1177/23337214221119322 . 10.1177/23337214221119322 . Gerontology and Geriatric Medicine
Portuguese version of the CDR plus NACC FTLD: Validation studies
Lima, Marisa; Tábuas-Pereira, Miguel; Durães, João; Faustino, Pedro; Simões, Mário R.; Kukull, Walter; Knopman, David S.; Santana, Isabel, 2022. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 1. 14. 2022. http://dx.doi.org/10.1002/dad2.12355 . 10.1002/dad2.12355 . published Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
Hemispheric patterns of reorganization of object processing in early Alzheimer’s Disease: a study along the entire ventral stream
Jorge, Lília; Canário, Nádia; Santana, Isabel; Castelo-Branco, Miguel, 2022. Journal of Alzheimer's Disease. 2022. accepted Journal of Alzheimer's Disease
Associations between cortical ß-amyloid burden, fornix microstructure and cognitive processing of faces, places, bodies and other visual objects in early Alzheimer's disease
Bourbon-Teles, José; Jorge, Lília; Canário, Nádia; Martins, Ricardo; Santana, Isabel; Castelo-Branco, Miguel, 2022. Hippocampus. 112 - 124. 2. 33. 2022. http://dx.doi.org/10.1002/hipo.23493 . 10.1002/hipo.23493 . Hippocampus
The CBI-R detects early behavioural impairment in genetic frontotemporal dementia
Nelson, Annabel; Russell, Lucy L.; Peakman, Georgia; Convery, Rhian S.; Bouzigues, Arabella; Greaves, Caroline V.; Bocchetta, Martina; et al, 2022. Annals of Clinical and Translational Neurology. 644 - 658. 5. 9. 2022. http://dx.doi.org/10.1002/acn3.51544 . 10.1002/acn3.51544 . published Annals of Clinical and Translational Neurology
Structural brain splitting is a hallmark of Granulin-related frontotemporal dementia
Gazzina, Stefano; Grassi, Mario; Premi, Enrico; Alberici, Antonella; Benussi, Alberto; Archetti, Silvana; Gasparotti, Roberto; et al, 2022. Neurobiology of Aging. 94 - 104. 114. 2022. http://dx.doi.org/10.1016/j.neurobiolaging.2022.02.009 . 10.1016/j.neurobiolaging.2022.02.009 . published Neurobiology of Aging
Development of a sensitive trial-ready poly(GP) CSF biomarker assay for C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis
Wilson, Katherine M; Katona, Eszter; Glaria, Idoia; Carcolé, Mireia; Swift, Imogen J; Sogorb-Esteve, Aitana; Heller, Carolin; et al, 2022. Journal of Neurology, Neurosurgery & Psychiatry. 761 - 771. 7. 93. 2022. http://dx.doi.org/10.1136/jnnp-2021-328710 . 10.1136/jnnp-2021-328710 . published Journal of Neurology, Neurosurgery & Psychiatry
The Road to Personalized Medicine in Alzheimer’s Disease: The Use of Artificial Intelligence
Silva-Spínola, Anuschka; Baldeiras, Inês; Arrais, Joel P.; Santana, Isabel, 2022. Biomedicines. 2. 10. 2022. http://dx.doi.org/10.3390/biomedicines10020315 . 10.3390/biomedicines10020315 . published Biomedicines
Diagnostic accuracy of cerebrospinal fluid biomarkers in genetic prion diseases
Schmitz, Matthias; Villar-Piqué, Anna; Hermann, Peter; Escaramís, Geòrgia; Calero, Miguel; Chen, Cao; Kruse, Niels; et al, 2022. Brain. 700 - 712. 2. 145. 2022. http://dx.doi.org/10.1093/brain/awab350 . 10.1093/brain/awab350 . published Brain
Temporal order of clinical and biomarker changes in familial frontotemporal dementia
Staffaroni, Adam M.; Quintana, Melanie; Wendelberger, Barbara; Heuer, Hilary W.; Russell, Lucy L.; Cobigo, Yann; Wolf, Amy; et al, 2022. Nature Medicine. 2194 - 2206. 10. 28. 2022. http://dx.doi.org/10.1038/s41591-022-01942-9 . 10.1038/s41591-022-01942-9 . published Nature Medicine
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum
Jansen, Willemijn J.; Janssen, Olin; Tijms, Betty M.; Vos, Stephanie J. B.; Ossenkoppele, Rik; Visser, Pieter Jelle; Aarsland, Dag; et al, 2022. JAMA Neurology. 3. 79. 2022. http://dx.doi.org/10.1001/jamaneurol.2021.5216 . 10.1001/jamaneurol.2021.5216 . published JAMA Neurology
Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia
Sogorb-Esteve, Aitana; Nilsson, Johanna; Swift, Imogen J.; Heller, Carolin; Bocchetta, Martina; Russell, Lucy L.; Peakman, Georgia; et al, 2022. Alzheimer's Research & Therapy. 1. 14. 2022. http://dx.doi.org/10.1186/s13195-022-01042-3 . 10.1186/s13195-022-01042-3 . published Alzheimer's Research & Therapy
Impairment of episodic memory in genetic frontotemporal dementia: A GENFI study
Poos, Jackie M.; Russell, Lucy L.; Peakman, Georgia; Bocchetta, Martina; Greaves, Caroline V.; Jiskoot, Lize C.; Ende, Emma L.; et al, 2021. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 1. 13. 2021. http://dx.doi.org/10.1002/dad2.12185 . 10.1002/dad2.12185 . published Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
HPLC method for the determination of antiepileptic drugs in human saliva and its application in therapeutic drug monitoring
Carona, Andreia; Bicker, Joana; Silva, Rui; Silva, Ana; Santana, Isabel; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana, 2021. Journal of Pharmaceutical and Biomedical Analysis. 197. 2021. http://dx.doi.org/10.1016/j.jpba.2021.113961 . 10.1016/j.jpba.2021.113961 . published Journal of Pharmaceutical and Biomedical Analysis
Differential early subcortical involvement in genetic FTD within the GENFI cohort
Bocchetta, Martina; Todd, Emily G.; Peakman, Georgia; Cash, David M.; Convery, Rhian S.; Russell, Lucy L.; Thomas, David L.; et al, 2021. NeuroImage: Clinical. 30. 2021. http://dx.doi.org/10.1016/j.nicl.2021.102646 . 10.1016/j.nicl.2021.102646 . published NeuroImage: Clinical
Practice effects in genetic frontotemporal dementia and at-risk individuals: a GENFI study
Öijerstedt, Linn; Andersson, Christin; Jelic, Vesna; van Swieten, John Cornelis; Jiskoot, Lize C; Seelaar, Harro; Borroni, Barbara; et al, 2021. Journal of Neurology, Neurosurgery & Psychiatry. jnnp - 2021. 2021. http://dx.doi.org/10.1136/jnnp-2021-327005 . 10.1136/jnnp-2021-327005 . published Journal of Neurology, Neurosurgery & Psychiatry
Toulouse-Piéron Cancellation Test: Normative scores for the Portuguese Population
Lima, Marisa; Baeta, Elia; Duro, Diana; Tábuas-Pereira, Miguel; Valério, Daniela; Freitas, Sandra; Simões, Mário R; Santana, Isabel, 2021. Applied Neuropsychologist: Adult. 2021. accepted Applied Neuropsychologist: Adult
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
Chia, Ruth; Sabir, Marya S.; Bandres-Ciga, Sara; Saez-Atienzar, Sara; Reynolds, Regina H.; Gustavsson, Emil; Walton, Ronald L.; et al, 2021. Nature Genetics. 2021. http://dx.doi.org/10.1038/s41588-021-00785-3 . 10.1038/s41588-021-00785-3 . published Nature Genetics
Investigating the Spatial Associations Between Amyloid-ß Deposition, Grey Matter Volume, and Neuroinflammation in Alzheimer’s Disease
Jorge, Lília; Martins, Ricardo; Canário, Nádia; Xavier, Carolina; Abrunhosa, Antero; Santana, Isabel; Castelo-Branco, Miguel, 2021. Journal of Alzheimer's Disease. 1 - 20. 2021. http://dx.doi.org/10.3233/jad-200840 . 10.3233/jad-200840 . published Journal of Alzheimer's Disease
A data-driven disease progression model of fluid biomarkers in genetic frontotemporal dementia
van der Ende, Emma L; Bron, Esther E; Poos, Jackie M; Jiskoot, Lize C; Panman, Jessica L; Papma, Janne M; Meeter, Lieke H; et al, 2021. Brain. 2021. http://dx.doi.org/10.1093/brain/awab382 . 10.1093/brain/awab382 . published Brain
Disease-related cortical thinning in presymptomatic granulin mutation carriers
Borrego-Écija, Sergi; Sala-Llonch, Roser; van Swieten, John; Borroni, Barbara; Moreno, Fermín; Masellis, Mario; Tartaglia, Carmela; et al, 2021. NeuroImage: Clinical. 29. 2021. http://dx.doi.org/10.1016/j.nicl.2020.102540 . 10.1016/j.nicl.2020.102540 . published NeuroImage: Clinical
Protective effects of cognitive and brain reserve in multiple sclerosis: Differential roles on social cognition and ‘classic cognition’
Machado, Rita; Lima, Cláudia; d'Almeida, Otília C.; Afonso, Ana; Macário, Carmo; Castelo-Branco, Miguel; Sousa, Lívia; Santana, Isabel; Batista, Sónia, 2021. Multiple Sclerosis and Related Disorders. 48. 2021. http://dx.doi.org/10.1016/j.msard.2020.102716 . 10.1016/j.msard.2020.102716 . published Multiple Sclerosis and Related Disorders
Progression of Behavioral Disturbances and Neuropsychiatric Symptoms in Patients With Genetic Frontotemporal Dementia
Benussi, Alberto; Premi, Enrico; Gazzina, Stefano; Brattini, Chiara; Bonomi, Elisa; Alberici, Antonella; Jiskoot, Lize; et al, 2021. JAMA Network Open. 1. 4. 2021. http://dx.doi.org/10.1001/jamanetworkopen.2020.30194 . 10.1001/jamanetworkopen.2020.30194 . published JAMA Network Open
Development and application of an HPLC-DAD technique for human plasma concentration monitoring of perampanel and lamotrigine in drug-resistant epileptic patients
Sabença, Rosa; Bicker, Joana; Silva, Rui; Carona, Andreia; Silva, Ana; Santana, Isabel; Sales, Francisco; Falcão, Amílcar; Fortuna, Ana, 2021. Journal of Chromatography B. 1162. 2021. http://dx.doi.org/10.1016/j.jchromb.2020.122491 . 10.1016/j.jchromb.2020.122491 . published Journal of Chromatography B
Neuropsychological features of progranulin-associated frontotemporal dementia: a nested case-control study
Lima, Marisa; Tábuas-Pereira, Miguel; Duro, Diana; Durães, João; Vieira, Daniela; Baldeiras, Inês; Almeida, MariaRosário; Santana, Isabel, 2021. Neural Regeneration Research. 5. 16. 2021. http://dx.doi.org/10.4103/1673-5374.297082 . 10.4103/1673-5374.297082 . published Neural Regeneration Research
Modelling the cascade of biomarker changes in GRN-related frontotemporal dementia
Panman, Jessica L; Venkatraghavan, Vikram; van der Ende, Emma L; Steketee, Rebecca M E; Jiskoot, Lize C; Poos, Jackie M; Dopper, Elise G P; et al, 2021. Journal of Neurology, Neurosurgery & Psychiatry. jnnp - 2020. 2021. http://dx.doi.org/10.1136/jnnp-2020-323541 . 10.1136/jnnp-2020-323541 . published Journal of Neurology, Neurosurgery & Psychiatry
Outcomes on Social and Classic Cognition in adults with Pediatric-onset Multiple Sclerosis
Massano, Catarina; Lima, Marisa; Monteiro, Isabel; Machado, Rita; Correia, Inês; Nunes, Carla Cecília; Macário, Carmo; et al, 2021. Multiple Sclerosis and Related Disorders. 53. 2021. http://dx.doi.org/10.1016/j.msard.2021.103071 . 10.1016/j.msard.2021.103071 . published Multiple Sclerosis and Related Disorders
Stratifying the Presymptomatic Phase of Genetic Frontotemporal Dementia by Serum NfL and pNfH: A Longitudinal Multicentre Study
Wilke, Carlo; Reich, Selina; Swieten, John C.; Borroni, Barbara; Sanchez-Valle, Raquel; Moreno, Fermin; Laforce, Robert; et al, 2021. Annals of Neurology. 33 - 47. 1. 91. 2021. http://dx.doi.org/10.1002/ana.26265 . 10.1002/ana.26265 . published Annals of Neurology
Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration
Rojas, Julio C.; Wang, Ping; Staffaroni, Adam M.; Heller, Carolin; Cobigo, Yann; Wolf, Amy; Goh, Sheng-Yang M.; et al, 2021. Neurology. e2296 - e2312. 18. 96. 2021. http://dx.doi.org/10.1212/wnl.0000000000011848 . 10.1212/wnl.0000000000011848 . published Neurology
Cognitive Trajectories Following Acute Infection in Older Patients With and Without Cognitive Impairment: An 1-Year Follow-Up Study
Silva, Ana Rita; Regueira, Patrícia; Cardoso, Ana Luísa; Baldeiras, Inês; Santana, Isabel; Cerejeira, Joaquim, 2021. Frontiers in Psychiatry. 12. 2021. http://dx.doi.org/10.3389/fpsyt.2021.754489 . 10.3389/fpsyt.2021.754489 . Frontiers in Psychiatry
Comparison of clinical rating scales in genetic frontotemporal dementia within the GENFI cohort
Peakman, Georgia; Russell, Lucy L; Convery, Rhian S; Nicholas, Jennifer M; Van Swieten, John C; Jiskoot, Lize C; Moreno, Fermin; et al, 2021. Journal of Neurology, Neurosurgery & Psychiatry. jnnp - 2021. 2021. http://dx.doi.org/10.1136/jnnp-2021-326868 . 10.1136/jnnp-2021-326868 . published Journal of Neurology, Neurosurgery & Psychiatry
Toulouse-Piéron Cancellation Test: Normative scores for the portuguese population
Marisa Lima; Élia Baeta; Diana Duro; Miguel Tábuas-Pereira; Daniela Valério; Sandra Freitas; Mário R. Simões; Isabel Santana, 2021. Applied Neuropsychology: Adult. 1 - 7. 2021. https://doi.org/10.1080/23279095.2021.1918694 . 10.1080/23279095.2021.1918694 . Applied Neuropsychology: Adult
The Revised Self-Monitoring Scale detects early impairment of social cognition in genetic frontotemporal dementia within the GENFI cohort
Franklin, Hannah D.; Russell, Lucy L.; Peakman, Georgia; Greaves, Caroline V.; Bocchetta, Martina; Nicholas, Jennifer; Poos, Jackie; et al, 2021. Alzheimer's Research & Therapy. 1. 13. 2021. http://dx.doi.org/10.1186/s13195-021-00865-w . 10.1186/s13195-021-00865-w . published Alzheimer's Research & Therapy
PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice
Messerschmidt, Clemens; Foddis, Marco; Blumenau, Sonja; Müller, Susanne; Bentele, Kajetan; Holtgrewe, Manuel; Kun-Rodrigues, Celia; et al, 2021. Scientific Reports. 1. 11. 2021. http://dx.doi.org/10.1038/s41598-021-84919-x . 10.1038/s41598-021-84919-x . published Scientific Reports
Serum neurofilament light chain as a surrogate of cognitive decline in sporadic and familial frontotemporal dementia
Silva-Spínola, Anuschka; Lima, Marisa; Leitão, Maria João; Durães, João; Tábuas-Pereira, Miguel; Almeida, Maria Rosário; Santana, Isabel; Baldeiras, Inês, 2021. European Journal of Neurology. 2021. http://dx.doi.org/10.1111/ene.15058 . 10.1111/ene.15058 . published European Journal of Neurology
Identification of a novel mutation in MEF2C gene in an atypical patient with frontotemporal lobar degeneration
Adrião, Andreia; Santana, Isabel; Ribeiro, Carolina; Cancela, M. Leonor; Conceição, Natércia; Grazina, Manuela, 2021. Neurological Sciences. 2021. http://dx.doi.org/10.1007/s10072-021-05269-0 . 10.1007/s10072-021-05269-0 . published Neurological Sciences
A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study
Bergström, Sofia; Öijerstedt, Linn; Remnestål, Julia; Olofsson, Jennie; Ullgren, Abbe; Seelaar, Harro; van Swieten, John C.; et al, 2021. Molecular Neurodegeneration. 1. 16. 2021. http://dx.doi.org/10.1186/s13024-021-00499-4 . 10.1186/s13024-021-00499-4 . Molecular Neurodegeneration
Knowing how to do it or doing it? A double dissociation between tool-gesture production and tool-gesture knowledge
Valério, Daniela; Santana, Isabel; Aguiar de Sousa, Diana; Schu, Guilherme; Leal, Gabriela; Pavão Martins, Isabel; Almeida, Jorge, 2021. Cortex. 449 - 464. 141. 2021. http://dx.doi.org/10.1016/j.cortex.2021.05.008 . 10.1016/j.cortex.2021.05.008 . published Cortex
Characterizing the Clinical Features and Atrophy Patterns of MAPT-Related Frontotemporal Dementia With Disease Progression Modeling
Young, Alexandra L.; Bocchetta, Martina; Russell, Lucy L.; Convery, Rhian S.; Peakman, Georgia; Todd, Emily; Cash, David M.; et al, 2021. Neurology. e941 - e952. 9. 97. 2021. http://dx.doi.org/10.1212/wnl.0000000000012410 . 10.1212/wnl.0000000000012410 . published Neurology
Vitamin D deficiency in a Portuguese epilepsy cohort: who is at risk and how to treat
Cunha, Inês Antunes; Saraiva, Ana MR.; Lopes, Pedro; Jesus-Ribeiro, Joana; Duarte, Cátia; Leitão, Fátima; Sales, Francisco; Santana, Isabel; Bento, Conceição, 2021. Epileptic Disorders. 291 - 298. 2. 23. 2021. http://dx.doi.org/10.1684/epd.2021.1268 . 10.1684/epd.2021.1268 . published Epileptic Disorders
Conceptual framework for the definition of preclinical and prodromal frontotemporal dementia
Benussi, Alberto; Alberici, Antonella; Samra, Kiran; Russell, Lucy L.; Greaves, Caroline V.; Bocchetta, Martina; Ducharme, Simon; et al, 2021. Alzheimer's & Dementia. 1408 - 1423. 7. 18. 2021. http://dx.doi.org/10.1002/alz.12485 . 10.1002/alz.12485 . published Alzheimer's & Dementia
Dissemination in time and space in presymptomatic granulin mutation carriers: a GENFI spatial chronnectome study
Premi, Enrico; Giunta, Marcello; Iraji, Armin; Rachakonda, Srinivas; Calhoun, Vince D.; Gazzina, Stefano; Benussi, Alberto; et al, 2021. Neurobiology of Aging. 155 - 167. 108. 2021. http://dx.doi.org/10.1016/j.neurobiolaging.2021.09.001 . 10.1016/j.neurobiolaging.2021.09.001 . published Neurobiology of Aging
A modified Camel and Cactus Test detects presymptomatic semantic impairment in genetic frontotemporal dementia within the GENFI cohort
Moore, Katrina; Convery, Rhian; Bocchetta, Martina; Neason, Mollie; Cash, David M.; Greaves, Caroline; Russell, Lucy L.; et al, 2020. Applied Neuropsychology: Adult. 1 - 8. 2020. http://dx.doi.org/10.1080/23279095.2020.1716357 . 10.1080/23279095.2020.1716357 . published Applied Neuropsychology: Adult
Single Word Repetition Predicts Long-Term Outcome of Aphasia Caused by an Ischemic Stroke
Tábuas-Pereira, Miguel; Beato-Coelho, José; Ribeiro, Joana; Nogueira, Ana Rita; Cruz, Luis; Silva, Fernando; Sargento-Freitas, João; Cordeiro, Gustavo; Santana, Isabel, 2020. Journal of Stroke and Cerebrovascular Diseases. 2. 29. 2020. http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.104566 . 10.1016/j.jstrokecerebrovasdis.2019.104566 . published Journal of Stroke and Cerebrovascular Diseases
Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study
Moore, Katrina M; Nicholas, Jennifer; Grossman, Murray; McMillan, Corey T; Irwin, David J; Massimo, Lauren; Van Deerlin, Vivianna M; et al, 2020. The Lancet Neurology. 145 - 156. 2. 19. 2020. http://dx.doi.org/10.1016/s1474-4422(19)30394-1 . 10.1016/s1474-4422(19)30394-1 . published The Lancet Neurology
Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia
Llorens, Franc; Hermann, Peter; Villar-Piqué, Anna; Diaz-Lucena, Daniela; Nägga, Katarina; Hansson, Oskar; Santana, Isabel; et al, 2020. Nature Communications. 1. 11. 2020. http://dx.doi.org/10.1038/s41467-020-14373-2 . 10.1038/s41467-020-14373-2 . published Nature Communications
Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies
Orme, Tatiana; Hernandez, Dena; Ross, Owen A.; Kun-Rodrigues, Celia; Darwent, Lee; Shepherd, Claire E.; Parkkinen, Laura; et al, 2020. Acta Neuropathologica Communications. 1. 8. 2020. http://dx.doi.org/10.1186/s40478-020-0879-z . 10.1186/s40478-020-0879-z . published Acta Neuropathologica Communications
Neuropsychological Contribution to Predict Conversion to Dementia in Patients with Mild Cognitive Impairment Due to Alzheimer’s Disease
Silva, Dina; Cardoso, Sandra; Guerreiro, Manuela; Maroco, João; Mendes, Tiago; Alves, Luísa; Nogueira, Joana; et al, 2020. Journal of Alzheimer's Disease. 1 - 12. 2020. http://dx.doi.org/10.3233/jad-191133 . 10.3233/jad-191133 . Journal of Alzheimer's Disease
Incidental findings in peer neurological examination
Reis Carneiro, Diogo; Tábuas-Pereira, Miguel; Santana, Isabel, 2020. Journal of the Neurological Sciences. 417. 2020. http://dx.doi.org/10.1016/j.jns.2020.117065 . 10.1016/j.jns.2020.117065 . published Journal of the Neurological Sciences
Neuropsychological profile of amyloid-positive versus amyloid-negative amnestic Mild Cognitive Impairment
Alves, Luísa; Cardoso, Sandra; Silva, Dina; Mendes, Tiago; Marôco, João; Nogueira, Joana; Lima, Marisa; et al, 2020. Journal of Neuropsychology. 2020. http://dx.doi.org/10.1111/jnp.12218 . 10.1111/jnp.12218 . published Journal of Neuropsychology
Alzheimer’s Disease Genetics: Review of Novel Loci Associated with Disease
Tábuas-Pereira, Miguel; Santana, Isabel; Guerreiro, Rita; Brás, José, 2020. Current Genetic Medicine Reports. 1 - 16. 1. 8. 2020. http://dx.doi.org/10.1007/s40142-020-00182-y . 10.1007/s40142-020-00182-y . Current Genetic Medicine Reports
C-reactive protein as a predictor of mild cognitive impairment conversion into Alzheimer's disease dementia
Fernandes, Andreia; Tábuas-Pereira, Miguel; Duro, Diana; Lima, Marisa; Gens, Helena; Santiago, Beatriz; Durães, João; et al, 2020. Experimental Gerontology. 2020. http://dx.doi.org/10.1016/j.exger.2020.111004 . 10.1016/j.exger.2020.111004 . published Experimental Gerontology
Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia
van der Ende, Emma L; Xiao, Meifang; Xu, Desheng; Poos, Jackie M; Panman, Jessica L; Jiskoot, Lize C; Meeter, Lieke H; et al, 2020. Journal of Neurology, Neurosurgery & Psychiatry. 612 - 621. 6. 91. 2020. http://dx.doi.org/10.1136/jnnp-2019-322493 . 10.1136/jnnp-2019-322493 . published Journal of Neurology, Neurosurgery & Psychiatry
Early symptoms in symptomatic and preclinical genetic frontotemporal lobar degeneration
Tavares, Tamara Paulo; Mitchell, Derek G V; Coleman, Kristy KL; Coleman, Brenda L; Shoesmith, Christen L; Butler, Christopher R; Santana, Isabel; et al, 2020. Journal of Neurology, Neurosurgery & Psychiatry. 975 - 984. 9. 91. 2020. http://dx.doi.org/10.1136/jnnp-2020-322987 . 10.1136/jnnp-2020-322987 . published Journal of Neurology, Neurosurgery & Psychiatry
Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia
Heller, Carolin; Foiani, Martha S; Moore, Katrina; Convery, Rhian; Bocchetta, Martina; Neason, Mollie; Cash, David M; et al, 2020. Journal of Neurology, Neurosurgery & Psychiatry. 263 - 270. 3. 91. 2020. http://dx.doi.org/10.1136/jnnp-2019-321954 . 10.1136/jnnp-2019-321954 . published Journal of Neurology, Neurosurgery & Psychiatry
Faster Cortical Thinning and Surface Area Loss in Presymptomatic and Symptomatic C9orf72 Repeat Expansion Adult Carriers
Le Blanc, Gabriella; Jetté Pomerleau, Vincent; McCarthy, Jillian; Borroni, Barbara; van Swieten, John; Galimberti, Daniela; Sanchez-Valle, Raquel; et al, 2020. Annals of Neurology. 2020. http://dx.doi.org/10.1002/ana.25748 . 10.1002/ana.25748 . published Annals of Neurology
A new tetra-plex fluorimetric assay for the quantification of cerebrospinal fluid ß-amyloid42, total-tau, phospho-tau and a-synuclein in the differential diagnosis of neurodegenerative dementia
Diaz-Lucena, Daniela; Escaramis, Geòrgia; Villar-Piqué, Anna; Hermann, Peter; Schmitz, Matthias; Varges, Daniela; Santana, Isabel; et al, 2020. Journal of Neurology. 2567 - 2581. 9. 267. 2020. http://dx.doi.org/10.1007/s00415-020-09870-9 . 10.1007/s00415-020-09870-9 . published Journal of Neurology
CYLD variants in frontotemporal dementia associated with severe memory impairment in a Portuguese cohort
Tábuas-Pereira, Miguel; Santana, Isabel; Kun-Rodrigues, Célia; Bras, Jose; Guerreiro, Rita, 2020. Brain. e67 - e67. 8. 143. 2020. http://dx.doi.org/10.1093/brain/awaa183 . 10.1093/brain/awaa183 . published Brain
Abnormal pain perception is associated with thalamo-cortico-striatal atrophy in C9orf72 expansion carriers in the GENFI cohort
Convery, Rhian S; Bocchetta, Martina; Greaves, Caroline V; Moore, Katrina M; Cash, David M; Van Swieten, John; Moreno, Fermin; et al, 2020. Journal of Neurology, Neurosurgery & Psychiatry. jnnp - 2020. 2020. http://dx.doi.org/10.1136/jnnp-2020-323279 . 10.1136/jnnp-2020-323279 . published Journal of Neurology, Neurosurgery & Psychiatry
Biomarker counseling, disclosure of diagnosis and follow-up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey
Frederiksen, Kristian S.; Nielsen, Thomas R.; Appollonio, Ildebrando; Andersen, Birgitte Bo; Riverol, Mario; Boada, Mercè; Ceccaldi, Mathieu; et al, 2020. International Journal of Geriatric Psychiatry. 2020. http://dx.doi.org/10.1002/gps.5427 . 10.1002/gps.5427 . published International Journal of Geriatric Psychiatry
The temporal stability of premorbid intelligence: A non-clinical 10-year follow-up study using the Irregular Word Reading Test (TeLPI)
Nogueira, J.; Gerardo, B.; Alves, L.; Santana, I.; Simões, M. R.; Freitas, S., 2020. Applied Neuropsychology: Adult. 1 - 6. 2020. http://dx.doi.org/10.1080/23279095.2020.1817744 . 10.1080/23279095.2020.1817744 . published Applied Neuropsychology: Adult
Estimates of Geriatric Delirium Frequency in Noncardiac Surgeries and Its Evaluation Across the Years: A Systematic Review and Meta-analysis
Silva, Ana Rita; Regueira, Patrícia; Albuquerque, Elisabete; Baldeiras, Inês; Cardoso, Ana Luísa; Santana, Isabel; Cerejeira, Joaquim, 2020. Journal of the American Medical Directors Association. 2020. http://dx.doi.org/10.1016/j.jamda.2020.08.017 . 10.1016/j.jamda.2020.08.017 . published Journal of the American Medical Directors Association
Patients with progranulin mutations overlap with the progressive dysexecutive syndrome: towards the definition of a frontoparietal dementia phenotype
Tábuas-Pereira, Miguel; Almeida, Maria Rosário; Duro, Diana; Lima, Marisa; Durães, João; Guerreiro, Rita; Brás, José; Baldeiras, Inês; Santana, Isabel, 2020. Brain Communications. 2. 2. 2020. http://dx.doi.org/10.1093/braincomms/fcaa126 . 10.1093/braincomms/fcaa126 . published Brain Communications
Brain functional network integrity sustains cognitive function despite atrophy in presymptomatic genetic frontotemporal dementia
Tsvetanov, Kamen A.; Gazzina, Stefano; Jones, P. Simon; Swieten, John; Borroni, Barbara; Sanchez-Valle, Raquel; Moreno, Fermin; et al, 2020. Alzheimer's & Dementia. 500 - 514. 3. 17. 2020. http://dx.doi.org/10.1002/alz.12209 . 10.1002/alz.12209 . published Alzheimer's & Dementia
Early-onset phenotype of bi-allelic GRN mutations
Neuray, Caroline; Sultan, Tipu; Alvi, Javeira Raza; Franca, Marcondes C; Assmann, Birgit; Wagner, Matias; Canafoglia, Laura; et al, 2020. Brain. e22 - e22. 2. 144. 2020. http://dx.doi.org/10.1093/brain/awaa414 . 10.1093/brain/awaa414 . published Brain
Pathophysiology of Blood–Brain Barrier Permeability Throughout the Different Stages of Ischemic Stroke and Its Implication on Hemorrhagic Transformation and Recovery
Bernardo-Castro, Sara; Sousa, João André; Brás, Ana; Cecília, Carla; Rodrigues, Bruno; Almendra, Luciano; Machado, Cristina; et al, 2020. Frontiers in Neurology. 11. 2020. http://dx.doi.org/10.3389/fneur.2020.594672 . 10.3389/fneur.2020.594672 . published Frontiers in Neurology
Apathy in presymptomatic genetic frontotemporal dementia predicts cognitive decline and is driven by structural brain changes
Malpetti, Maura; Jones, P. Simon; Tsvetanov, Kamen A.; Rittman, Timothy; Swieten, John C.; Borroni, Barbara; Sanchez-Valle, Raquel; et al, 2020. Alzheimer's & Dementia. 2020. http://dx.doi.org/10.1002/alz.12252 . 10.1002/alz.12252 . published Alzheimer's & Dementia
Face-Specific Perceptual Distortions Reveal A View- and Orientation-Independent Face Template
Almeida, Jorge; Freixo, Andreia; Tábuas-Pereira, Miguel; Herald, Sarah B.; Valério, Daniela; Schu, Guilherme; Duro, Diana; et al, 2020. Current Biology. 2020. http://dx.doi.org/10.1016/j.cub.2020.07.067 . 10.1016/j.cub.2020.07.067 . published Current Biology
APOE ¿4-TOMM40L Haplotype Increases the Risk of Mild Cognitive Impairment Conversion to Alzheimer’s Disease
Cardoso, Remy; Lemos, Carolina; Oliveiros, Bárbara; Almeida, Maria Rosário; Baldeiras, Inês; Pereira, Cláudia Fragão; Santos, Ana; et al, 2020. Journal of Alzheimer's Disease. 587 - 601. 2. 78. 2020. http://dx.doi.org/10.3233/jad-200556 . 10.3233/jad-200556 . published Journal of Alzheimer's Disease
Increased C-X-C Motif Chemokine Ligand 12 Levels in Cerebrospinal Fluid as a Candidate Biomarker in Sporadic Amyotrophic Lateral Sclerosis
Andrés-Benito, Pol; Povedano, Mònica; Domínguez, Raúl; Marco, Carla; Colomina, Maria J.; López-Pérez, Óscar; Santana, Isabel; et al, 2020. International Journal of Molecular Sciences. 22. 21. 2020. http://dx.doi.org/10.3390/ijms21228680 . 10.3390/ijms21228680 . published International Journal of Molecular Sciences
Interplay Between Macular Retinal Changes and White Matter Integrity in Early Alzheimer’s Disease
Alves, Carolina; Jorge, Lília; Canário, Nádia; Santiago, Beatriz; Santana, Isabel; Castelhano, João; Ambrósio, António Francisco; Bernardes, Rui; Castelo-Branco, Miguel, 2019. Journal of Alzheimer's Disease. 723 - 732. 3. 70. 2019. http://dx.doi.org/10.3233/jad-190152 . 10.3233/jad-190152 . published Journal of Alzheimer's Disease
Retinal texture biomarkers may help to discriminate between Alzheimer’s, Parkinson’s, and healthy controls
Nunes, Ana; Silva, Gilberto; Duque, Cristina; Januário, Cristina; Santana, Isabel; Ambrósio, António Francisco; Castelo-Branco, Miguel; Bernardes, Rui, 2019. PLOS ONE. 6. 14. 2019. http://dx.doi.org/10.1371/journal.pone.0218826 . 10.1371/journal.pone.0218826 . published PLOS ONE
Clock drawing test in mild cognitive impairment: Correlation with cerebral perfusion in single-photon emission computed tomography.
Duro, Diana; Cerveira, Pedro; Santiago, Beatriz; Cunha, Maria João; Pedroso de Lima, João Manuel; Botelho, Maria Amália; Santana, Isabel, 2019. Neuropsychology. 617 - 632. 5. 33. 2019. http://dx.doi.org/10.1037/neu0000549 . 10.1037/neu0000549 . published Neuropsychology
Semi-quantification and grading of amyloid PET: A project of the European Alzheimer's Disease Consortium (EADC)
Chincarini, A.; Peira, E.; Morbelli, S.; Pardini, M.; Bauckneht, M.; Arbizu, J.; Castelo-Branco, M.; et al, 2019. NeuroImage: Clinical. 23. 2019. http://dx.doi.org/10.1016/j.nicl.2019.101846 . 10.1016/j.nicl.2019.101846 . published NeuroImage: Clinical
Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study
Lleó, Alberto; Alcolea, Daniel; Martínez-Lage, Pablo; Scheltens, Philip; Parnetti, Lucilla; Poirier, Judes; Simonsen, Anja H.; et al, 2019. Alzheimer's & Dementia. 742 - 753. 6. 15. 2019. http://dx.doi.org/10.1016/j.jalz.2019.01.015 . 10.1016/j.jalz.2019.01.015 . published Alzheimer's & Dementia
Heritability and genetic variance of dementia with Lewy bodies
Guerreiro, Rita; Escott-Price, Valentina; Hernandez, Dena G.; Kun-Rodrigues, Celia; Ross, Owen A.; Orme, Tatiana; Neto, Joao Luis; et al, 2019. Neurobiology of Disease. 492 - 501. 127. 2019. http://dx.doi.org/10.1016/j.nbd.2019.04.004 . 10.1016/j.nbd.2019.04.004 . published Neurobiology of Disease
Association between Adipokines and Biomarkers of Alzheimer’s Disease: A Cross-Sectional Study
Letra, Liliana; Matafome, Paulo; Rodrigues, Tiago; Duro, Diana; Lemos, Raquel; Baldeiras, Inês; Patrício, Miguel; et al, 2019. Journal of Alzheimer's Disease. 725 - 735. 2. 67. 2019. http://dx.doi.org/10.3233/jad-180669 . 10.3233/jad-180669 . published Journal of Alzheimer's Disease
Validation study of the Toulouse-Piéron cancellation test for Portuguese patients with Mild Cognitive Impairment and Alzheimer's disease
Lima, Marisa; Duro, Diana; Freitas, Sandra; Simões, Mário; Santana, I, 2019. Sinapse. 26 - 35. 1-2. 19. 2019. http://www.sinapse.pt/section.php?id=29 . published Sinapse
Can Subjective Memory Complaints Identify Aß Positive and Aß Negative Amnestic Mild Cognitive Impairment Patients?
Mendes, Tiago; Cardoso, Sandra; Guerreiro, Manuela; Maroco, João; Silva, Dina; Alves, Luísa; Schmand, Ben; et al, 2019. Journal of Alzheimer's Disease. 1103 - 1111. 4. 70. 2019. http://dx.doi.org/10.3233/jad-190414 . 10.3233/jad-190414 . published Journal of Alzheimer's Disease
Education modulates brain maintenance in presymptomatic frontotemporal dementia
Gazzina, Stefano; Grassi, Mario; Premi, Enrico; Cosseddu, Maura; Alberici, Antonella; Archetti, Silvana; Gasparotti, Roberto; et al, 2019. Journal of Neurology, Neurosurgery & Psychiatry. 1124 - 1130. 10. 90. 2019. http://dx.doi.org/10.1136/jnnp-2019-320439 . 10.1136/jnnp-2019-320439 . published Journal of Neurology, Neurosurgery & Psychiatry
Increased CSF tau is associated with a higher risk of seizures in patients with Alzheimer's disease
Tábuas-Pereira, Miguel; Durães, João; Lopes, Joana; Sales, Francisco; Bento, Conceição; Duro, Diana; Santiago, Beatriz; et al, 2019. Epilepsy & Behavior. 207 - 209. 98. 2019. http://dx.doi.org/10.1016/j.yebeh.2019.06.033 . 10.1016/j.yebeh.2019.06.033 . published Epilepsy & Behavior
The inner fluctuations of the brain in presymptomatic Frontotemporal Dementia: The chronnectome fingerprint
Premi, Enrico; Calhoun, Vince D.; Diano, Matteo; Gazzina, Stefano; Cosseddu, Maura; Alberici, Antonella; Archetti, Silvana; et al, 2019. NeuroImage. 645 - 654. 189. 2019. http://dx.doi.org/10.1016/j.neuroimage.2019.01.080 . 10.1016/j.neuroimage.2019.01.080 . published NeuroImage
Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study
van der Ende, Emma L; Meeter, Lieke H; Poos, Jackie M; Panman, Jessica L; Jiskoot, Lize C; Dopper, Elise G P; Papma, Janne M; et al, 2019. The Lancet Neurology. 1103 - 1111. 12. 18. 2019. http://dx.doi.org/10.1016/s1474-4422(19)30354-0 . 10.1016/s1474-4422(19)30354-0 . published The Lancet Neurology
Lower CSF Amyloid-Beta1–42 Predicts a Higher Mortality Rate in Frontotemporal Dementia
Vieira, Daniela; Durães, João; Baldeiras, Inês; Santiago, Beatriz; Duro, Diana; Lima, Marisa; Leitão, Maria João; Tábuas-Pereira, Miguel; Santana, Isabel, 2019. Diagnostics. 4. 9. 2019. http://dx.doi.org/10.3390/diagnostics9040162 . 10.3390/diagnostics9040162 . published Diagnostics
Clinical validation of the Lumipulse G cerebrospinal fluid assays for routine diagnosis of Alzheimer’s disease
Leitão, Maria João; Silva-Spínola, Anuschka; Santana, Isabel; Olmedo, Veronica; Nadal, Alicia; Le Bastard, Nathalie; Baldeiras, Inês, 2019. Alzheimer's Research & Therapy. 1. 11. 2019. http://dx.doi.org/10.1186/s13195-019-0550-8 . 10.1186/s13195-019-0550-8 . published Alzheimer's Research & Therapy
Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study
van Maurik, Ingrid S; Vos, Stephanie J; Bos, Isabelle; Bouwman, Femke H; Teunissen, Charlotte E; Scheltens, Philip; Barkhof, Frederik; et al, 2019. The Lancet Neurology. 1034 - 1044. 11. 18. 2019. http://dx.doi.org/10.1016/s1474-4422(19)30283-2 . 10.1016/s1474-4422(19)30283-2 . published The Lancet Neurology
Prevalence of the apolipoprotein E e4 allele in amyloid ß positive subjects across the spectrum of Alzheimer's disease
Mattsson, Niklas; Groot, Colin; Jansen, Willemijn J.; Landau, Susan M.; Villemagne, Victor L.; Engelborghs, Sebastiaan; Mintun, Mark M.; et al, 2018. Alzheimer's & Dementia. 913 - 924. 7. 14. 2018. http://dx.doi.org/10.1016/j.jalz.2018.02.009 . 10.1016/j.jalz.2018.02.009 . published Alzheimer's & Dementia
Escala de Avaliação da Doença de Alzheimer - Subescala Cognitiva (ADAS-Cog): Dados Normativos para a População Portuguesa
Nogueira, Joana; Freitas, Sandra; Duro, Diana; Tábuas-Pereira, Miguel; Guerreiro, Manuela; Almeida, Jorge; Santana, Isabel, 2018. Acta Médica Portuguesa. 2. 31. 2018. http://dx.doi.org/10.20344/amp.8859 . 10.20344/amp.8859 . published Acta Médica Portuguesa
Validation study of the Alzheimer’s disease assessment scale–cognitive subscale (ADAS-Cog) for the Portuguese patients with mild cognitive impairment and Alzheimer’s disease
Nogueira, Joana; Freitas, Sandra; Duro, Diana; Almeida, Jorge; Santana, Isabel, 2018. The Clinical Neuropsychologist. 46 - 59. sup1. 32. 2018. http://dx.doi.org/10.1080/13854046.2018.1454511 . 10.1080/13854046.2018.1454511 . published The Clinical Neuropsychologist
Underlying Biological Processes in Mild Cognitive Impairment: Amyloidosis Versus Neurodegeneration
Santana, Isabel; Baldeiras, Inês; Santiago, Beatriz; Duro, Diana; Freitas, Sandra; Pereira, Miguel Tábuas; Almeida, Maria Rosário; Oliveira, Catarina Resende, 2018. Journal of Alzheimer's Disease. S647 - S657. s1. 64. 2018. http://dx.doi.org/10.3233/jad-179908 . 10.3233/jad-179908 . published Journal of Alzheimer's Disease
Addition of the Aß42/40 ratio to the cerebrospinal fluid biomarker profile increases the predictive value for underlying Alzheimer’s disease dementia in mild cognitive impairment
Baldeiras, Inês; Santana, Isabel; Leitão, Maria João; Gens, Helena; Pascoal, Rui; Tábuas-Pereira, Miguel; Beato-Coelho, José; et al, 2018. Alzheimer's Research & Therapy. 1. 10. 2018. http://dx.doi.org/10.1186/s13195-018-0362-2 . 10.1186/s13195-018-0362-2 . published Alzheimer's Research & Therapy
Advanced MRI study of migrainous infarction presenting as cortical laminar necrosis – Case report and literature review
Morais, Ricardo; Sobral, Filipe; Cunha, Gil; Brito, Olga; Santana, Isabel, 2018. Clinical Neurology and Neurosurgery. 82 - 85. 167. 2018. http://dx.doi.org/10.1016/j.clineuro.2018.02.016 . 10.1016/j.clineuro.2018.02.016 . published Clinical Neurology and Neurosurgery
Cerebrospinal fluid neurofilament light levels in neurodegenerative dementia: Evaluation of diagnostic accuracy in the differential diagnosis of prion diseases
Zerr, Inga; Schmitz, Matthias; Karch, André; Villar-Piqué, Anna; Kanata, Eirini; Golanska, Ewa; Díaz-Lucena, Daniela; et al, 2018. Alzheimer's & Dementia. 751 - 763. 6. 14. 2018. http://dx.doi.org/10.1016/j.jalz.2017.12.008 . 10.1016/j.jalz.2017.12.008 . published Alzheimer's & Dementia
Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study
Guerreiro, Rita; Ross, Owen A; Kun-Rodrigues, Celia; Hernandez, Dena G; Orme, Tatiana; Eicher, John D; Shepherd, Claire E; et al, 2018. The Lancet Neurology. 64 - 74. 1. 17. 2018. http://dx.doi.org/10.1016/s1474-4422(17)30400-3 . 10.1016/s1474-4422(17)30400-3 . published The Lancet Neurology
Influence of Butyrylcholinesterase in Progression of Mild Cognitive Impairment to Alzheimer’s Disease
Gabriel, António José; Almeida, Maria Rosário; Ribeiro, Maria Helena; Carneiro, Diogo; Valério, Daniela; Pinheiro, Ana Cristina; Pascoal, Rui; Santana, Isabel; Baldeiras, Inês, 2018. Journal of Alzheimer's Disease. 1097 - 1105. 3. 61. 2018. http://dx.doi.org/10.3233/jad-170695 . 10.3233/jad-170695 . published Journal of Alzheimer's Disease
Association of Cerebral Amyloid-ß Aggregation With Cognitive Functioning in Persons Without Dementia
Jansen, Willemijn J.; Ossenkoppele, Rik; Tijms, Betty M.; Fagan, Anne M.; Hansson, Oskar; Klunk, William E.; van der Flier, Wiesje M.; et al, 2018. JAMA Psychiatry. 1. 75. 2018. http://dx.doi.org/10.1001/jamapsychiatry.2017.3391 . 10.1001/jamapsychiatry.2017.3391 . published JAMA Psychiatry
Common and rare TBK1 variants in early-onset Alzheimer disease in a European cohort
Verheijen, Jan; van der Zee, Julie; Gijselinck, Ilse; Van den Bossche, Tobi; Dillen, Lubina; Heeman, Bavo; Gómez-Tortosa, Estrella; et al, 2018. Neurobiology of Aging. 245.e1 - 245.e7. 62. 2018. http://dx.doi.org/10.1016/j.neurobiolaging.2017.10.012 . 10.1016/j.neurobiolaging.2017.10.012 . published Neurobiology of Aging
Using the Rasch analysis for the psychometric validation of the Irregular Word Reading Test (TeLPI): A Portuguese test for the assessment of premorbid intelligence
Freitas, Sandra; Prieto, Gerardo; Simões, Mário R.; Nogueira, Joana; Santana, Isabel; Martins, Cristina; Alves, Lara, 2018. The Clinical Neuropsychologist. 60 - 76. sup1. 32. 2018. http://dx.doi.org/10.1080/13854046.2018.1468481 . 10.1080/13854046.2018.1468481 . published The Clinical Neuropsychologist
Validity and Clinical Utility of Different Clock Drawing Test Scoring Systems in Multiple Forms of Dementia
Duro, Diana; Tábuas-Pereira, Miguel; Freitas, Sandra; Santiago, Beatriz; Botelho, Maria Amália; Santana, Isabel, 2018. Journal of Geriatric Psychiatry and Neurology. 114 - 122. 3. 31. 2018. http://dx.doi.org/10.1177/0891988718774432 . 10.1177/0891988718774432 . published Journal of Geriatric Psychiatry and Neurology
Rare nonsynonymous variants in SORT1 are associated with increased risk for frontotemporal dementia
Philtjens, Stéphanie; Van Mossevelde, Sara; van der Zee, Julie; Wauters, Eline; Dillen, Lubina; Vandenbulcke, Mathieu; Vandenberghe, Rik; et al, 2018. Neurobiology of Aging. 181.e3 - 181.e10. 66. 2018. http://dx.doi.org/10.1016/j.neurobiolaging.2018.02.011 . 10.1016/j.neurobiolaging.2018.02.011 . published Neurobiology of Aging
Aphasia Rapid Test: Estudos de Tradução, Adaptação e Validação para a População Portuguesa
Tábuas-Pereira, Miguel; Freitas, Sandra; Beato-Coelho, José; Ribeiro, Joana; Parra, Joana; Martins, Cristina; Silva, Miguel; et al, 2018. Acta Médica Portuguesa. 5. 31. 2018. http://dx.doi.org/10.20344/amp.9090 . 10.20344/amp.9090 . published Acta Médica Portuguesa
No supportive evidence for TIA1 gene mutations in a European cohort of ALS-FTD spectrum patients
Baradaran-Heravi, Yalda; Dillen, Lubina; Nguyen, Hung Phuoc; Van Mossevelde, Sara; Baets, Jonathan; De Jonghe, Peter; Engelborghs, Sebastiaan; et al, 2018. Neurobiology of Aging. 293.e9 - 293.e11. 69. 2018. http://dx.doi.org/10.1016/j.neurobiolaging.2018.05.005 . 10.1016/j.neurobiolaging.2018.05.005 . published Neurobiology of Aging
Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer’s Disease Cerebrospinal Fluid Biomarkers
Ramos de Matos, Mafalda; Ferreira, Catarina; Herukka, Sanna-Kaisa; Soininen, Hilkka; Janeiro, André; Santana, Isabel; Baldeiras, Inês; et al, 2018. Journal of Alzheimer's Disease. 639 - 652. 2. 66. 2018. http://dx.doi.org/10.3233/jad-180512 . 10.3233/jad-180512 . published Journal of Alzheimer's Disease
Discriminative capacity and construct validity of the Clock Drawing Test in Mild Cognitive Impairment and Alzheimer’s disease
Duro, Diana; Freitas, Sandra; Tábuas-Pereira, Miguel; Santiago, Beatriz; Botelho, Maria Amália; Santana, Isabel, 2018. The Clinical Neuropsychologist. 1159 - 1174. 7. 33. 2018. http://dx.doi.org/10.1080/13854046.2018.1532022 . 10.1080/13854046.2018.1532022 . published The Clinical Neuropsychologist
The Quadruple Helix-Based Innovation Model of Reference Sites for Active and Healthy Ageing in Europe: The Ageing@Coimbra Case Study
Malva, João O.; Amado, Alda; Rodrigues, Alexandra; Mota-Pinto, Anabela; Cardoso, Ana F.; Teixeira, Ana M.; Todo-Bom, Ana; et al, 2018. Frontiers in Medicine. 5. 2018. http://dx.doi.org/10.3389/fmed.2018.00132 . 10.3389/fmed.2018.00132 . published Frontiers in Medicine
The Head Turning Sign in Dementia and Mild Cognitive Impairment: Its Relationship to Cognition, Behavior, and Cerebrospinal Fluid Biomarkers
Durães, João; Tábuas-Pereira, Miguel; Araújo, Rui; Duro, Diana; Baldeiras, Inês; Santiago, Beatriz; Santana, Isabel, 2018. Dementia and Geriatric Cognitive Disorders. 42 - 49. 1-2. 46. 2018. http://dx.doi.org/10.1159/000486531 . 10.1159/000486531 . published Dementia and Geriatric Cognitive Disorders
Cerebrospinal Fluid Total Prion Protein in the Spectrum of Prion Diseases
Villar-Piqué, Anna; Schmitz, Matthias; Lachmann, Ingolf; Karch, André; Calero, Olga; Stehmann, Christiane; Sarros, Shannon; et al, 2018. Molecular Neurobiology. 2811 - 2821. 4. 56. 2018. http://dx.doi.org/10.1007/s12035-018-1251-1 . 10.1007/s12035-018-1251-1 . published Molecular Neurobiology
Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aß species
Oliveira, Francisco; Leuzy, Antoine; Castelhano, João; Chiotis, Konstantinos; Hasselbalch, Steen Gregers; Rinne, Juha; Mendonça, Alexandre; et al, 2018. NeuroImage: Clinical. 603 - 610. 20. 2018. http://dx.doi.org/10.1016/j.nicl.2018.08.023 . 10.1016/j.nicl.2018.08.023 . published NeuroImage: Clinical
The neural basis of fatigue in multiple sclerosis: a multimodal MRI approach
Novo, Ana Margarida; Batista, Sonia; Alves, Carolina; d’Almeida, Otília C.; Marques, Inês Brás; Macário, Carmo; Santana, Isabel; et al, 2018. Neurology: Clinical Practice. 492 - 500. 6. 8. 2018. http://dx.doi.org/10.1212/cpj.0000000000000545 . 10.1212/cpj.0000000000000545 . published Neurology: Clinical Practice
De profundis, Valsa Lenta de José Cardoso Pires: a indesejada exegese neurológica
Araújo, Rui; Santo, Gustavo Cordeiro; Santana, I, 2017. Sinapse. 6 - 11. 2. 17. 2017. published Sinapse
Clinical Reasoning: A 55-year-old man with rapidly progressive dementia and parkinsonism
Tábuas-Pereira, Miguel; Santana, Isabel; Santo, Gustavo Cordeiro, 2017. Neurology. e182 - e187. 15. 89. 2017. http://dx.doi.org/10.1212/wnl.0000000000004495 . 10.1212/wnl.0000000000004495 . published Neurology
Disconnection as a mechanism for social cognition impairment in multiple sclerosis
Batista, Sonia; Alves, Carolina; d’Almeida, Otília C.; Afonso, Ana; Félix-Morais, Ricardo; Pereira, João; Macário, Carmo; et al, 2017. Neurology. 38 - 45. 1. 89. 2017. http://dx.doi.org/10.1212/wnl.0000000000004060 . 10.1212/wnl.0000000000004060 . published Neurology
The frequency and influence of dementia risk factors in prodromal Alzheimer's disease
Bos, Isabelle; Vos, Stephanie J.; Frölich, Lutz; Kornhuber, Johannes; Wiltfang, Jens; Maier, Wolfgang; Peters, Oliver; et al, 2017. Neurobiology of Aging. 33 - 40. 56. 2017. http://dx.doi.org/10.1016/j.neurobiolaging.2017.03.034 . 10.1016/j.neurobiolaging.2017.03.034 . published Neurobiology of Aging
Transthyretin stability is critical in assisting beta amyloid clearance- Relevance of transthyretin stabilization in Alzheimer's disease
Alemi, Mobina; Silva, Sara C.; Santana, Isabel; Cardoso, Isabel, 2017. CNS Neuroscience & Therapeutics. 605 - 619. 7. 23. 2017. http://dx.doi.org/10.1111/cns.12707 . 10.1111/cns.12707 . published CNS Neuroscience & Therapeutics
Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies
Kun-Rodrigues, Celia; Ross, Owen A.; Orme, Tatiana; Shepherd, Claire; Parkkinen, Laura; Darwent, Lee; Hernandez, Dena; et al, 2017. Neurobiology of Aging. 214.e13 - 214.e15. 49. 2017. http://dx.doi.org/10.1016/j.neurobiolaging.2016.08.023 . 10.1016/j.neurobiolaging.2016.08.023 . published Neurobiology of Aging
The impact of automated hippocampal volumetry on diagnostic confidence in patients with suspected Alzheimer's disease: A European Alzheimer's Disease Consortium study
Bosco, Paolo; Redolfi, Alberto; Bocchetta, Martina; Ferrari, Clarissa; Mega, Anna; Galluzzi, Samantha; Austin, Mark; et al, 2017. Alzheimer's & Dementia. 1013 - 1023. 9. 13. 2017. http://dx.doi.org/10.1016/j.jalz.2017.01.019 . 10.1016/j.jalz.2017.01.019 . published Alzheimer's & Dementia
Association between butyrylcholinesterase and cerebrospinal fluid biomarkers in Alzheimer’s disease patients
Gabriel, António José; Almeida, Maria Rosário; Ribeiro, Maria Helena; Durães, João; Tábuas-Pereira, Miguel; Pinheiro, Ana Cristina; Pascoal, Rui; Santana, Isabel; Baldeiras, Inês, 2017. Neuroscience Letters. 101 - 106. 641. 2017. http://dx.doi.org/10.1016/j.neulet.2017.01.036 . 10.1016/j.neulet.2017.01.036 . published Neuroscience Letters
Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer’s Disease Patients and Controls after Correction for Ventricular Volumes
van Waalwijk van Doorn, Linda J.C.; Gispert, Juan D.; Kuiperij, H. Bea; Claassen, Jurgen A.H.R.; Arighi, Andrea; Baldeiras, Inês; Blennow, Kaj; et al, 2017. Journal of Alzheimer's Disease. 543 - 555. 2. 56. 2017. http://dx.doi.org/10.3233/jad-160668 . 10.3233/jad-160668 . published Journal of Alzheimer's Disease
TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis
van der Zee, Julie; Gijselinck, Ilse; Van Mossevelde, Sara; Perrone, Federica; Dillen, Lubina; Heeman, Bavo; Bäumer, Veerle; et al, 2017. Human Mutation. 297 - 309. 3. 38. 2017. http://dx.doi.org/10.1002/humu.23161 . 10.1002/humu.23161 . published Human Mutation
Adiponectin and sporadic Alzheimer’s disease: Clinical and molecular links
Letra, Liliana; Rodrigues, Tiago; Matafome, Paulo; Santana, Isabel; Seiça, Raquel, 2017. Frontiers in Neuroendocrinology. 1 - 11. 52. 2017. http://dx.doi.org/10.1016/j.yfrne.2017.10.002 . 10.1016/j.yfrne.2017.10.002 . published Frontiers in Neuroendocrinology
Theory of Mind and Executive Functions are Dissociated in Multiple Sclerosis
Batista, Sonia; Freitas, Sandra; Afonso, Ana; Macário, Carmo; Sousa, Lívia; Cunha, Luís; Santana, Isabel, 2017. Archives of Clinical Neuropsychology. 541 - 551. 5. 33. 2017. http://dx.doi.org/10.1093/arclin/acx101 . 10.1093/arclin/acx101 . Archives of Clinical Neuropsychology
Predicting progression of mild cognitive impairment to dementia using neuropsychological data: a supervised learning approach using time windows
Pereira, Telma; Lemos, Luís; Cardoso, Sandra; Silva, Dina; Rodrigues, Ana; Santana, Isabel; de Mendonça, Alexandre; Guerreiro, Manuela; Madeira, Sara C., 2017. BMC Medical Informatics and Decision Making. 1. 17. 2017. http://dx.doi.org/10.1186/s12911-017-0497-2 . 10.1186/s12911-017-0497-2 . published BMC Medical Informatics and Decision Making
Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer’s disease
De Roeck, Arne; Van den Bossche, Tobi; van der Zee, Julie; Verheijen, Jan; De Coster, Wouter; Van Dongen, Jasper; Dillen, Lubina; et al, 2017. Acta Neuropathologica. 475 - 487. 3. 134. 2017. http://dx.doi.org/10.1007/s00401-017-1714-x . 10.1007/s00401-017-1714-x . published Acta Neuropathologica
Neuroimaging Correlates of Frontotemporal Dementia Associated with SQSTM1 Mutations
Luis, Elkin; Ortiz, Alexandra; Eudave, Luis; Ortega-Cubero, Sara; Borroni, Barbara; van der Zee, Julie; Gazzina, Stefano; et al, 2016. Journal of Alzheimer's Disease. 303 - 313. 1. 53. 2016. http://dx.doi.org/10.3233/jad-160006 . 10.3233/jad-160006 . published Journal of Alzheimer's Disease
Portuguese family with the co-occurrence of frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis phenotypes due to progranulin gene mutation
Almeida, Maria R.; Macário, Maria C.; Ramos, Lina; Baldeiras, Inês; Ribeiro, Maria H.; Santana, Isabel, 2016. Neurobiology of Aging. 200.e1 - 200.e5. 41. 2016. http://dx.doi.org/10.1016/j.neurobiolaging.2016.02.019 . 10.1016/j.neurobiolaging.2016.02.019 . published Neurobiology of Aging
ABCA7 p.G215S as potential protective factor for Alzheimer's disease
Sassi, Celeste; Nalls, Michael A.; Ridge, Perry G.; Gibbs, Jesse R.; Ding, Jinhui; Lupton, Michelle K.; Troakes, Claire; et al, 2016. Neurobiology of Aging. 235.e1 - 235.e9. 46. 2016. http://dx.doi.org/10.1016/j.neurobiolaging.2016.04.004 . 10.1016/j.neurobiolaging.2016.04.004 . published Neurobiology of Aging
Prosopagnosia as the Presenting Symptom of Whipple Disease
Tábuas-Pereira, Miguel; Vicente, Margarida; Coelho, Filomena; Santana, Isabel, 2016. Cognitive And Behavioral Neurology. 100 - 106. 2. 29. 2016. http://dx.doi.org/10.1097/wnn.0000000000000091 . 10.1097/wnn.0000000000000091 . published Cognitive And Behavioral Neurology
Mini-Mental State Examination: Screening and diagnosis of cognitive decline, using new normative data
Santana, I; Duro, Diana; Lemos, Raquel; Simões, Mário; Freitas, Sandra, 2016. Acta Médica Portuguesa. 240 - 248. 4. 29. 2016. https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6889 . published Acta Médica Portuguesa
Sporadic Creutzfeldt–Jakob disease diagnostic accuracy is improved by a new CSF ELISA 14-3-3¿ assay
Leitão, M.J.; Baldeiras, I.; Almeida, M.R.; Ribeiro, M.H.; Santos, A.C.; Ribeiro, M.; Tomás, J.; et al, 2016. Neuroscience. 398 - 407. 322. 2016. http://dx.doi.org/10.1016/j.neuroscience.2016.02.057 . 10.1016/j.neuroscience.2016.02.057 . Neuroscience
Portuguese version of Wechsler Memory Scale–3rd edition’s utility with demented elderly adults
Gonçalves, Cátia; Pinho, Maria S.; Cruz, Vítor; Gens, Helena; Oliveira, Fátima; Pais, Joana; Rente, José; Santana, Isabel; Santos, José M., 2016. Applied Neuropsychology: Adult. 212 - 225. 3. 24. 2016. http://dx.doi.org/10.1080/23279095.2015.1135440 . 10.1080/23279095.2015.1135440 . published Applied Neuropsychology: Adult
Construct and diagnostic validities of the Free and Cued Selective Reminding Test in the Alzheimer’s disease spectrum
Lemos, Raquel; Marôco, João; Simões, Mário R.; Santana, Isabel, 2016. Journal of Clinical and Experimental Neuropsychology. 913 - 924. 8. 38. 2016. http://dx.doi.org/10.1080/13803395.2016.1176996 . 10.1080/13803395.2016.1176996 . published Journal of Clinical and Experimental Neuropsychology
Pittsburgh compound B imaging and cerebrospinal fluid amyloid-ß in a multicentre European memory clinic study
Leuzy, Antoine; Chiotis, Konstantinos; Hasselbalch, Steen G.; Rinne, Juha O.; de Mendonça, Alexandre; Otto, Markus; Lleó, Alberto; et al, 2016. Brain. 2540 - 2553. 9. 139. 2016. http://dx.doi.org/10.1093/brain/aww160 . 10.1093/brain/aww160 . published Brain
MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's disease
Guedes, J.R.; Santana, I.; Cunha, C.; Duro, D.; Almeida, M.R.; Cardoso, A.M.; de Lima, M.C.P.; Cardoso, A.L., 2016. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 7 - 17. 3. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956620147&partnerID=MN8TOARS . 10.1016/j.dadm.2015.11.004 . Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
Pseudohypoparathyroidism type I-b with neurological involvement is associated with a homozygousPTH1Rmutation
Guerreiro, R.; Brás, J.; Batista, S.; Pires, P.; Ribeiro, M. H.; Almeida, M. R.; Oliveira, C.; Hardy, J.; Santana, I., 2016. Genes, Brain and Behavior. 669 - 677. 7. 15. 2016. http://dx.doi.org/10.1111/gbb.12308 . 10.1111/gbb.12308 . published Genes, Brain and Behavior
The Montreal Cognitive Assessment (MoCA) as a screening test for cognitive dysfunction in multiple sclerosis
Freitas, Sandra; Batista, Sónia; Afonso, Ana Cristina; Simões, Mário R.; de Sousa, Lívia; Cunha, Luís; Santana, Isabel, 2016. Applied Neuropsychology: Adult. 57 - 70. 1. 25. 2016. http://dx.doi.org/10.1080/23279095.2016.1243108 . 10.1080/23279095.2016.1243108 . published Applied Neuropsychology: Adult
CSF Tau proteins reduce misdiagnosis of sporadic Creutzfeldt–Jakob disease suspected cases with inconclusive 14-3-3 result
Leitão, M. J.; Baldeiras, I.; Almeida, M. R.; Ribeiro, M. H.; Santos, A. C.; Ribeiro, M.; Tomás, J.; et al, 2016. Journal of Neurology. 1847 - 1861. 9. 263. 2016. http://dx.doi.org/10.1007/s00415-016-8209-x . 10.1007/s00415-016-8209-x . published Journal of Neurology
Impairment of social cognition in multiple sclerosis: Amygdala atrophy is the main predictor
Batista, Sonia; d’Almeida, Otília C; Afonso, Ana; Freitas, Sandra; Macário, Carmo; Sousa, Lívia; Castelo-Branco, Miguel; Santana, Isabel; Cunha, Luís, 2016. Multiple Sclerosis Journal. 1358 - 1366. 10. 23. 2016. http://dx.doi.org/10.1177/1352458516680750 . 10.1177/1352458516680750 . published Multiple Sclerosis Journal
Three-Dimensional Face Recognition in Mild Cognitive Impairment: A Psychophysical and Structural MR Study
Lemos, Raquel; Santana, Isabel; Caetano, Gina; Bernardino, Inês; Morais, Ricardo; Farivar, Reza; Castelo-Branco, Miguel, 2016. Journal of the International Neuropsychological Society. 744 - 754. 7. 22. 2016. http://dx.doi.org/10.1017/s135561771600059x . 10.1017/s135561771600059x . published Journal of the International Neuropsychological Society
The free and cued selective reminding test for predicting progression to Alzheimer's disease in patients with mild cognitive impairment: A prospective longitudinal study
Lemos, R.; Marôco, J.; Simões, M.R.; Santiago, B.; Tomás, J.; Santana, I., 2015. Journal of Neuropsychology. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930725382&partnerID=MN8TOARS . 10.1111/jnp.12075 . Journal of Neuropsychology
Free and Cued Selective Reminding Test is superior to the Wechsler Memory Scale in discriminating mild cognitive impairment from Alzheimer's disease
Lemos, R.; Cunha, C.; Marôco, J.; Afonso, A.; Simões, M.R.; Santana, I., 2015. Geriatrics and Gerontology International. 961 - 968. 8. 15. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937921570&partnerID=MN8TOARS . 10.1111/ggi.12374 . Geriatrics and Gerontology International
Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage
Vos, S.J.B.; Verhey, F.; Frölich, L.; Kornhuber, J.; Wiltfang, J.; Maier, W.; Peters, O.; et al, 2015. Brain. 1327 - 1338. 5. 138. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929363392&partnerID=MN8TOARS . 10.1093/brain/awv029 . Brain
Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases
Lleó, A.; Cavedo, E.; Parnetti, L.; Vanderstichele, H.; Herukka, S.K.; Andreasen, N.; Ghidoni, R.; et al, 2015. Nature Reviews Neurology. 41 - 55. 1. 11. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84926244431&partnerID=MN8TOARS . 10.1038/nrneurol.2014.232 . Nature Reviews Neurology
Does Caffeine Consumption Modify Cerebrospinal Fluid Amyloid-ß Levels in Patients with Alzheimer's Disease?
Travassos, M.; Santana, I.; Baldeiras, I.; Tsolaki, M.; Gkatzima, O.; Genc, S.; Yener, G.G.; et al, 2015. Journal of Alzheimer's Disease. 1069 - 1078. 4. 47. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939450783&partnerID=MN8TOARS . 10.3233/JAD-150374 . Journal of Alzheimer's Disease
The epidemiology of dementia and Alzheimer disease in Portugal: Estimations of prevalence and treatment-costs | Epidemiologia da demência e da doença de Alzheimer em Portugal: Estimativas da prevalência e dos encargos financeiros com a medicação
Santana, I.; Farinha, F.; Freitas, S.; Rodrigues, V.; Carvalho, Á., 2015. Acta Medica Portuguesa. 182 - 188. 2. 28. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930450663&partnerID=MN8TOARS . Acta Medica Portuguesa
Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: A European early-onset dementia consortium study
Cuyvers, E.; van der Zee, J.; Bettens, K.; Engelborghs, S.; Vandenbulcke, M.; Robberecht, C.; Dillen, L.; et al, 2015. Neurobiology of Aging. 2005.e15 - 2005.e22. 5. 36. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84933180683&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2015.02.014 . Neurobiology of Aging
Genetic variation of MT-ND genes in frontotemporal lobar degeneration: Biochemical phenotype-genotype correlation
Gaspar, R.; Santana, I.; Mendes, C.; Fernandes, A.S.; Duro, D.; Simões, M.; Luís, D.; Santos, M.J.; Grazina, M., 2015. Neurodegenerative Diseases. 70 - 80. 2. 15. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928938610&partnerID=MN8TOARS . 10.1159/000380766 . Neurodegenerative Diseases
Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease
Mota, S.I.; Costa, R.O.; Ferreira, I.L.; Santana, I.; Caldeira, G.L.; Padovano, C.; Fonseca, A.C.; et al, 2015. Biochimica et Biophysica Acta - Molecular Basis of Disease. 1428 - 1441. 7. 1852. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928128412&partnerID=MN8TOARS . 10.1016/j.bbadis.2015.03.015 . Biochimica et Biophysica Acta - Molecular Basis of Disease
Selective reminding and free and cued selective reminding in mild cognitive impairment and alzheimer disease
Lemos, R.; Afonso, A.; Martins, C.; Waters, J.H.; Blanco, F.S.; Simões, M.R.; Santana, I., 2015. Applied Neuropsychology:Adult. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941686789&partnerID=MN8TOARS . 10.1080/23279095.2015.1012761 . Applied Neuropsychology:Adult
Rare Variants in PLD3 Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort
Cacace, R.; Van den Bossche, T.; Engelborghs, S.; Geerts, N.; Laureys, A.; Dillen, L.; Graff, C.; et al, 2015. Human Mutation. 1226 - 1235. 12. 36. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946555494&partnerID=MN8TOARS . 10.1002/humu.22908 . Human Mutation
[The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs].
Santana I; Farinha F; Freitas S; Rodrigues V; Carvalho Å, 2015. 2015. http://europepmc.org/abstract/med/26061508 .
Cerebrospinal fluid Aß40 is similarly reduced in patients with Frontotemporal Lobar Degeneration and Alzheimer's Disease
Baldeiras, I.; Santana, I.; Leitão, M.J.; Ribeiro, M.H.; Pascoal, R.; Duro, D.; Lemos, R.; et al, 2015. Journal of the Neurological Sciences. 308 - 316. 1-2. 358. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84956762726&partnerID=MN8TOARS . 10.1016/j.jns.2015.09.022 . Journal of the Neurological Sciences
Scaling cognitive domains of the Montreal Cognitive Assessment: An analysis using the Partial Credit Model
Freitas, S.; Prieto, G.; Simões, M.R.; Santana, I., 2015. Archives of Clinical Neuropsychology. 435 - 447. 5. 30. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84943645294&partnerID=MN8TOARS . 10.1093/arclin/acv027 . Archives of Clinical Neuropsychology
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.
Jansen WJ; Ossenkoppele R; Knol DL; Tijms BM; Scheltens P; Verhey FR; Visser PJ; et al, 2015. 2015. http://europepmc.org/abstract/med/25988462 . 10.1001/jama.2015.4668 .
Severe post-influenza (H1N1) encephalitis involving pulvinar nuclei in an adult patient
Tomás, J.; Macário, M.C.; Gaspar, E.; Santana, I., 2015. BMJ Case Reports. 2015. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84951838741&partnerID=MN8TOARS . 10.1136/bcr-2015-212667 . BMJ Case Reports
The free and cued selective reminding test for predicting progression to Alzheimer's disease in patients with mild cognitive impairment: A prospective longitudinal study.
Lemos R; Marôco J; Simões MR; Santiago B; Tomás J; Santana I, 2015. 2015. http://europepmc.org/abstract/med/26058529 .
The free and cued selective reminding test: Validation for mild cognitive impairment and Alzheimer's disease
Lemos, R.; Simões, M.R.; Santiago, B.; Santana, I., 2015. Journal of Neuropsychology. 242 - 257. 2. 9. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941192522&partnerID=MN8TOARS . 10.1111/jnp.12048 . Journal of Neuropsychology
Selective reminding and free and cued selective reminding in mild cognitive impairment and alzheimer disease.
Lemos R; Afonso A; Martins C; Waters JH; Blanco FS; Simões MR; Santana I, 2015. 2015. http://europepmc.org/abstract/med/26375308 .
Biparietal variant of alzheimer's disease: A rare presentation of a common disease
Marques, I.B.; Tábuas-Pereira, M.; Milheiro, M.; Santana, I., 2015. BMJ Case Reports. 2015. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84921631412&partnerID=MN8TOARS . 10.1136/bcr-2014-207011 . BMJ Case Reports
The Relevance of Sociodemographic and Health Variables on MMSE Normative Data
Freitas, S.; Simões, M.R.; Alves, L.; Santana, I., 2015. Applied Neuropsychology:Adult. 311 - 319. 4. 22. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84934437185&partnerID=MN8TOARS . 10.1080/23279095.2014.926455 . Applied Neuropsychology:Adult
Characterization of an FTLD-PDB family with the coexistence of SQSTM1 mutation and hexanucleotide (G4C2) repeat expansion in C9orf72 gene.
Almeida MR; Letra L; Pires P; Santos A; Rebelo O; Guerreiro R; van der Zee J; Van Broeckhoven C; Santana I, 2015. 2015. http://europepmc.org/abstract/med/26839080 . 10.1016/j.neurobiolaging.2015.12.015 .
The Portuguese version of Addenbrooke's cognitive examination-revised (ACE-R) in the diagnosis of subcortical vascular dementia and Alzheimers disease
Gonçalves, C.; Pinho, M.S.; Cruz, V.; Pais, J.; Gens, H.; Oliveira, F.; Santana, I.; Rente, J.; Santos, J.M., 2015. Aging, Neuropsychology, and Cognition. 473 - 485. 4. 22. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84927799324&partnerID=MN8TOARS . 10.1080/13825585.2014.984652 . Aging, Neuropsychology, and Cognition
The use of biomarkers for the etiologic diagnosis of MCI in Europe: An EADC survey
Bocchetta, M.; Galluzzi, S.; Kehoe, P.G.; Aguera, E.; Bernabei, R.; Bullock, R.; Ceccaldi, M.; et al, 2015. Alzheimer's and Dementia. 195 - 206.e1. 2. 11. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929751761&partnerID=MN8TOARS . 10.1016/j.jalz.2014.06.006 . Alzheimer's and Dementia
Montreal cognitive assessment (MoCA): Cutoff points for mild cognitive impairment, Alzheimer's disease, frontotemporal dementia and vascular dementia | Montreal cognitive assessment (MoCA): Pontos de corte no défice cognitivo ligeiro, doença de alzheimer, demência frontotemporal e demência vascular
Freitas, S.; Simões, M.R.; Santana, I., 2014. Sinapse. 18 - 30. 1. 14. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900445658&partnerID=MN8TOARS . Sinapse
Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration
Van Der Zee, J.; Van Langenhove, T.; Kovacs, G.G.; Dillen, L.; Deschamps, W.; Engelborghs, S.; Matej, R.; et al, 2014. Acta Neuropathologica. 397 - 410. 3. 128. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906313820&partnerID=MN8TOARS . 10.1007/s00401-014-1298-7 . Acta Neuropathologica
Progranulin peripheral levels as a screening tool for the identification of subjects with progranulin mutations in a portuguese cohort
Almeida, M.R.; Baldeiras, I.; Ribeiro, M.H.; Santiago, B.; Machado, C.; Massano, J.; Guimarães, J.; Oliveira, C.R.; Santana, I., 2014. Neurodegenerative Diseases. 214 - 223. 4. 13. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893838273&partnerID=MN8TOARS . 10.1159/000352022 . Neurodegenerative Diseases
Pharmacological treatment of Alzheimer's Disease: Results and expectations after two decades of investigation and treatment | Tratamento farmacológico da Doença de Alzheimer: Resultados e expectativas de duas décadas de investigação e tratamento
Santana, I.; Santiago, B.; Cunha, L., 2014. Sinapse. 9 - 20. 1 SUPPL. 1. 14. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84900434426&partnerID=MN8TOARS . Sinapse
Frontotemporal dementia: Neuroanatomical correlates of an atypical presentation
Felix-Morais, R.; Letra, L.; Duro, D.; Santana, I., 2014. BMJ Case Reports. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904893226&partnerID=MN8TOARS . 10.1136/bcr-2014-205089 . BMJ Case Reports
Obesity as a risk factor for Alzheimer's disease: the role of adipocytokines
Letra, L.; Santana, I.; Seiça, R., 2014. Metabolic brain disease. 563 - 568. 3. 29. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944152641&partnerID=MN8TOARS . 10.1007/s11011-014-9501-z . Metabolic brain disease
The free and cued selective reminding test distinguishes frontotemporal dementia from Alzheimer's disease
Lemos, R.; Duro, D.; Simões, M.R.; Santana, I., 2014. Archives of Clinical Neuropsychology. 670 - 679. 7. 29. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84911385641&partnerID=MN8TOARS . 10.1093/arclin/acu031 . Archives of Clinical Neuropsychology
Psychometric properties of the montreal cognitive assessment (MoCA): An analysis using the Rasch Model
Freitas, S.; Prieto, G.; Simões, M.R.; Santana, I., 2014. Clinical Neuropsychologist. 65 - 83. 1. 28. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893919349&partnerID=MN8TOARS . 10.1080/13854046.2013.870231 . Clinical Neuropsychologist
Premorbid IQ influence on screening tests' scores in healthy patients and patients with cognitive impairment
Alves, L.; Simões, M.R.; Martins, C.; Freitas, S.; Santana, I., 2013. Journal of Geriatric Psychiatry and Neurology. 117 - 126. 2. 26. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884483148&partnerID=MN8TOARS . 10.1177/0891988713484194 . Journal of Geriatric Psychiatry and Neurology
TREM2 variants in Alzheimer's disease.
Guerreiro R; Wojtas A; Bras J; Carrasquillo M; Rogaeva E; Majounie E; Cruchaga C; et al, 2013. 2013. http://europepmc.org/abstract/med/23150934 . 10.1056/NEJMoa1211851 .
The clock drawing test: Portuguese norms, by age and education, for three different scoring systems
Santana, I.; Duro, D.; Freitas, S.; Alves, L.; Simões, M.R., 2013. Archives of Clinical Neuropsychology. 375 - 387. 4. 28. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879179846&partnerID=MN8TOARS . 10.1093/arclin/act016 . Archives of Clinical Neuropsychology
Do MCI patients with vitamin B12 deficiency have distinctive cognitive deficits?
Silva, D.; Albers, U.; Santana, I.; Vicente, M.; Martins, I.P.; Verdelho, A.; Guerreiro, M.; De-Mendonça, A., 2013. BMC Research Notes. 1. 6. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883519459&partnerID=MN8TOARS . 10.1186/1756-0500-6-357 . BMC Research Notes
Impaired processing of 3D motion-defined faces in mild cognitive impairment and healthy aging: An fMRI study
Graewe, B.; Lemos, R.; Ferreira, C.; Santana, I.; Farivar, R.; De Weerd, P.; Castelo-Branco, M., 2013. Cerebral Cortex. 2489 - 2499. 10. 23. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887901963&partnerID=MN8TOARS . 10.1093/cercor/bhs246 . Cerebral Cortex
Prediction of long-term (5 years) conversion to dementia using neuropsychological tests in a memory clinic setting
Silva, D.; Guerreiro, M.; Santana, I.; Rodrigues, A.; Cardoso, S.; Maroco, J.; De Mendonça, A., 2013. Journal of Alzheimer's Disease. 681 - 689. 3. 34. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876368687&partnerID=MN8TOARS . 10.3233/JAD-122098 . Journal of Alzheimer's Disease
TeLPI performance in subjects with mild cognitive impairment and alzheimer disease: A validation study
Alves, L.; Simões, M.R.; Martins, C.; Freitas, S.; Santana, I., 2013. Alzheimer Disease and Associated Disorders. 324 - 329. 4. 27. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888133081&partnerID=MN8TOARS . 10.1097/WAD.0b013e31827bdc8c . Alzheimer Disease and Associated Disorders
Montreal cognitive assessment: Validation study for mild cognitive impairment and alzheimer disease
Freitas, S.; Simões, M.R.; Alves, L.; Santana, I., 2013. Alzheimer Disease and Associated Disorders. 37 - 43. 1. 27. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874272210&partnerID=MN8TOARS . 10.1097/WAD.0b013e3182420bfe . Alzheimer Disease and Associated Disorders
A Pan-European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats
van der Zee, J.; Gijselinck, I.; Dillen, L.; Van Langenhove, T.; Theuns, J.; Engelborghs, S.; Philtjens, S.; et al, 2013. Human Mutation. 363 - 373. 2. 34. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873093810&partnerID=MN8TOARS . 10.1002/humu.22244 . Human Mutation
Prodromal metabolic phenotype in MCI cybrids: Implications for Alzheimer's disease
Silva, D.F.; Santana, I.; Esteves, A.R.; Baldeiras, I.; Arduino, D.M.; Oliveira, C.R.; Cardoso, S.M., 2013. Current Alzheimer Research. 180 - 190. 2. 10. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875000768&partnerID=MN8TOARS . 10.2174/1567205011310020008 . Current Alzheimer Research
P2-009: The chemokines IL8 and MIP-1b distinguish mild cognitive impairment from early stage Alzheimer's disease
Gonçalves, Milene; Santana, Isabel; Francisco, Natália; Cunha, Catarina; Batista, Sonia; Kodandaraman, Geema; Souto-Carneiro, Margarida, 2012. Alzheimer's & Dementia. P266 - P267. 4S_Part_7. 8. 2012. http://dx.doi.org/10.1016/j.jalz.2012.05.712 . 10.1016/j.jalz.2012.05.712 . published Alzheimer's & Dementia
Differences between early and late-onset Alzheimer's disease in neuropsychological tests
Sá, F.; Pinto, P.; Cunha, C.; Lemos, R.; Letra, L.; Simões, M.; Santana, I., 2012. Frontiers in Neurology. MAY. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865835722&partnerID=MN8TOARS . 10.3389/fneur.2012.00081 . Frontiers in Neurology
Serial position effects in Alzheimer's disease, mild cognitive impairment, and normal aging: Predictive value for conversion to dementia
Cunha, C.; Guerreiro, M.; De Mendona, A.; Oliveira, P.E.; Santana, I., 2012. Journal of Clinical and Experimental Neuropsychology. 841 - 852. 8. 34. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866618686&partnerID=MN8TOARS . 10.1080/13803395.2012.689814 . Journal of Clinical and Experimental Neuropsychology
Epigenetic regulation of BACE1 in Alzheimer's disease patients and in transgenic mice
Marques, S.C.F.; Lemos, R.; Ferreiro, E.; Martins, M.; de Mendonça, A.; Santana, I.; Outeiro, T.F.; Pereira, C.M.F., 2012. Neuroscience. 256 - 266. 220. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864770859&partnerID=MN8TOARS . 10.1016/j.neuroscience.2012.06.029 . Neuroscience
CSF biomarkers for the early diagnosis of Alzheimer's disease in a routine clinical setting - The first Portuguese study | Biomarcadores do LCR no diagnóstico precoce da doença de Alzheimer em ambiente clínico de rotina - o primeiro estudo em Portugal
Baldeiras, I.; Santana, I.; Garrucho, M.H.; Pascoal, R.; Lemos, R.; Santiago, B.; de Oliveira, C.R., 2012. Sinapse. 14 - 22. 2. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872921979&partnerID=MN8TOARS . Sinapse
Transthyretin decrease in plasma of MCI and AD patients: Investigation of mechanisms for disease modulation
Ribeiro, C.A.; Santana, I.; Oliveira, C.; Baldeiras, I.; Moreira, J.; Saraiva, M.J.; Cardoso, I., 2012. Current Alzheimer Research. 881 - 889. 8. 9. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867714724&partnerID=MN8TOARS . 10.2174/156720512803251057 . Current Alzheimer Research
Construct validity of the Montreal Cognitive Assessment (MoCA)
Freitas, S.; Simões, M.R.; Marôco, J.; Alves, L.; Santana, I., 2012. Journal of the International Neuropsychological Society. 242 - 250. 2. 18. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857757347&partnerID=MN8TOARS . 10.1017/S1355617711001573 . Journal of the International Neuropsychological Society
Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer's disease
Guerreiro, R.J.; Lohmann, E.; Kinsella, E.; Brás, J.M.; Luu, N.; Gurunlian, N.; Dursun, B.; et al, 2012. Neurobiology of Aging. 5. 33. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858335381&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2011.10.009 . Neurobiology of Aging
The clock drawing test: Influence of sociodemographic and health variables in the portuguese population | O teste do desenho do relógio: Influência das variáveis sóciodemográficas e de saúde na população portuguesa
Duro, D.; Freitas, S.; Alves, L.; Simões, M.R.; Santana, I., 2012. Sinapse. 5 - 12. 1. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863808623&partnerID=MN8TOARS . Sinapse
Amyloid ß-induced ER stress is enhanced under mitochondrial dysfunction conditions
Costa, R.O.; Ferreiro, E.; Martins, I.; Santana, I.; Cardoso, S.M.; Oliveira, C.R.; Pereira, C.M.F., 2012. Neurobiology of Aging. 4. 33. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856951448&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2011.04.011 . Neurobiology of Aging
Temporal integration of 3D coherent motion cues defining visual objects of unknown orientation is impaired in amnestic mild cognitive impairment and Alzheimer's disease
Lemos, R.; Figueiredo, P.; Santana, I.; Simões, M.R.; Castelo-Branco, M., 2012. Journal of Alzheimer's Disease. 885 - 896. 4. 28. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858018563&partnerID=MN8TOARS . 10.3233/JAD-2011-110719 . Journal of Alzheimer's Disease
Montreal Cognitive Assessment (MoCA): Validation study for frontotemporal dementia
Freitas, S.; Simões, M.R.; Alves, L.; Duro, D.; Santana, I., 2012. Journal of Geriatric Psychiatry and Neurology. 146 - 154. 3. 25. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868372524&partnerID=MN8TOARS . 10.1177/0891988712455235 . Journal of Geriatric Psychiatry and Neurology
Multiple dural arteriovenous fistulas presenting as rapidly progressive dementia
Mendonça, N.; Santos, G.; Duro, D.; MacHado, E.; Goulão, A.; Santana, I., 2012. Neurologist. 130 - 132. 3. 18. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861145878&partnerID=MN8TOARS . 10.1097/NRL.0b013e318251e695 . Neurologist
Differences between Early and Late-Onset Alzheimer's Disease in Neuropsychological Tests.
Sá F; Pinto P; Cunha C; Lemos R; Letra L; Simões M; Santana I, 2012. 2012. http://europepmc.org/abstract/med/22593755 .
Comparison of four verbal memory tests for the diagnosis and predictive value of mild cognitive impairment.
Silva D; Guerreiro M; Maroco J; Santana I; Rodrigues A; Bravo Marques J; de Mendonça A, 2012. 2012. http://europepmc.org/abstract/med/22590473 . 10.1159/000336224 .
Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer's disease.
Guerreiro, R.J.; Lohmann, E.; Kinsella, E.; Brás, J.M.; Luu, N.; Gurunlian, N.; Dursun, B.; et al, 2012. Neurobiology of aging. 5. 33. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866136235&partnerID=MN8TOARS . Neurobiology of aging
Montreal cognitive assessment: Influence of sociodemographic and health variables
Freitas, S.; Simões, M.R.; Alves, L.; Santana, I., 2012. Archives of Clinical Neuropsychology. 165 - 175. 2. 27. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862255082&partnerID=MN8TOARS . 10.1093/arclin/acr116 . Archives of Clinical Neuropsychology
Montreal cognitive assessment (MoCA): Validation study for vascular dementia
Freitas, S.; Simões, M.R.; Alves, L.; Vicente, M.; Santana, I., 2012. Journal of the International Neuropsychological Society. 1031 - 1040. 6. 18. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868377857&partnerID=MN8TOARS . 10.1017/S135561771200077X . Journal of the International Neuropsychological Society
P2-277: The clock drawing test: Normative data for the Portuguese population
Santana, Isabel; Duro, Diana; Alves, Lara; Freitas, Sandra; Simões, Mário, 2012. Alzheimer's & Dementia. P359 - P360. 4S_Part_10. 8. 2012. http://dx.doi.org/10.1016/j.jalz.2012.05.985 . 10.1016/j.jalz.2012.05.985 . Alzheimer's & Dementia
Montreal Cognitive Assessment (MoCA): Normative study for the Portuguese population
Freitas, S.; Simões, M.R.; Alves, L.; Santana, I., 2011. Journal of Clinical and Experimental Neuropsychology. 989 - 996. 9. 33. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855657605&partnerID=MN8TOARS . 10.1080/13803395.2011.589374 . Journal of Clinical and Experimental Neuropsychology
P1-470: Validity study of the Montreal cognitive assessment in patients with vascular dementia
Santana, Isabel; Freitas, Sandra; Simões, Mário Rodrigues, 2011. Alzheimer's & Dementia. S264 - S264. 7. 2011. http://dx.doi.org/10.1016/j.jalz.2011.05.752 . 10.1016/j.jalz.2011.05.752 . published Alzheimer's & Dementia
Data mining methods in the prediction of Dementia: A real-data comparison of the accuracy, sensitivity and specificity of linear discriminant analysis, logistic regression, neural networks, support vector machines, classification trees and random forests
Maroco, J.; Silva, D.; Rodrigues, A.; Guerreiro, M.; Santana, I.; De Mendonça, A., 2011. BMC Research Notes. 4. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051660823&partnerID=MN8TOARS . 10.1186/1756-0500-4-299 . BMC Research Notes
P1-435: Free and cued selective reminding in mild cognitive impairment and Alzheimer's disease
Lemos, Raquel; Afonso, Ana; Martins, Cristina; Simões, Mário; Santana, Isabel, 2011. Alzheimer's & Dementia. S252 - S252. 7. 2011. http://dx.doi.org/10.1016/j.jalz.2011.05.717 . 10.1016/j.jalz.2011.05.717 . Alzheimer's & Dementia
P1-476: Comparison of two verbal memory tests for the diagnosis and predictive value of MCI
Silva, Dina; de Mendonça, Alexandre; Santana, Isabel; Rodrigues, Ana; Maroco, João; Guerreiro, Manuela, 2011. Alzheimer's & Dementia. S266 - S266. 7. 2011. http://dx.doi.org/10.1016/j.jalz.2011.05.759 . 10.1016/j.jalz.2011.05.759 . published Alzheimer's & Dementia
P2-019: Memory decline and cerebrospinal fluid biomarkers in MCI
Baldeiras, Ines; Lemos, Raquel; Cunha, Catarina; Ribeiro, Maria Helena; Santiago, Beatriz; Oliveira, Catarina; Santana, Isabel, 2011. Alzheimer's & Dementia. S313 - S313. 7. 2011. http://dx.doi.org/10.1016/j.jalz.2011.05.909 . 10.1016/j.jalz.2011.05.909 . published Alzheimer's & Dementia
Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP
Guerreiro, R.J.; Baquero, M.; Blesa, R.; Boada, M.; Brás, J.M.; Bullido, M.J.; Calado, A.; et al, 2010. Neurobiology of Aging. 725 - 731. 5. 31. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950529014&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2008.06.012 . Neurobiology of Aging
Genetic variability in CLU and its association with Alzheimer's disease
Guerreiro, R.J.; Beck, J.; Gibbs, J.R.; Santana, I.; Rossor, M.N.; Schott, J.M.; Nalls, M.A.; et al, 2010. PLoS ONE. 3. 5. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949784437&partnerID=MN8TOARS . 10.1371/journal.pone.0009510 . PLoS ONE
The Portuguese who could no longer speak French: primary progressive aphasia in a bilingual man.
Machado A; Rodrigues M; Simões S; Santana I; Soares-Fernandes J, 2010. 2010. http://europepmc.org/abstract/med/20160239 . 10.1176/appi.neuropsych.22.1.123-s.e31 .
Validation studies of the Portuguese experimental version of the Montreal Cognitive Assessment (MoCA): Confirmatory factor analysis
Duro, D.; Simões, M.R.; Ponciano, E.; Santana, I., 2010. Journal of Neurology. 728 - 734. 5. 257. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954457477&partnerID=MN8TOARS . 10.1007/s00415-009-5399-5 . Journal of Neurology
Oxidative damage and progression to Alzheimer's disease in patients with mild cognitive impairment.
Baldeiras I; Santana I; Proença MT; Garrucho MH; Pascoal R; Rodrigues A; Duro D; Oliveira CR, 2010. 2010. http://europepmc.org/abstract/med/21504121 .
Primary bilateral thalamic astrocytoma presenting with head tremor, ataxia, and dementia.
Machado A; Ribeiro M; Rodrigues M; Ferreira C; Almeida R; Santana I; Castro L; Carpenter S, 2010. 2010. http://europepmc.org/abstract/med/20686149 . 10.1176/appi.neuropsych.22.3.352-e.e7 .
Oxidative damage and progression to Alzheimer's disease in patients with mild cognitive impairment
Baldeiras, I.; Santana, I.; Proença, M.T.; Garrucho, M.H.; Pascoal, R.; Rodrigues, A.; Duro, D.; Oliveira, C.R., 2010. Journal of Alzheimer's Disease. 1165 - 1177. 4. 21. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650467580&partnerID=MN8TOARS . 10.3233/JAD-2010-091723 . Journal of Alzheimer's Disease
The Portuguese who could no longer speak French: Primary progressive aphasia in a bilingual man
Machado, Á.; Rodrigues, M.; Simões, S.; Santana, I.; Soares-Fernandes, J., 2010. Journal of Neuropsychiatry and Clinical Neurosciences. 1. 22. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-76749161467&partnerID=MN8TOARS . Journal of Neuropsychiatry and Clinical Neurosciences
Primary bilateral thalamic astrocytoma presenting with head tremor, ataxia, and dementia
Machado, Á.; Ribeiro, M.; Rodrigues, M.; Ferreira, C.; Almeida, R.; Santana, I.; Castro, L.; Carpenter, S., 2010. Journal of Neuropsychiatry and Clinical Neurosciences. 3. 22. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955455926&partnerID=MN8TOARS . Journal of Neuropsychiatry and Clinical Neurosciences
Sporadic Creutzfeldt-Jakob disease causing a 2-years slowly progressive isolated dementia
MacHado, A.; Ribeiro, M.; Rodrigues, M.; Ferreira, C.; Baldeiras, I.; Ribeiro, M.H.; Santana, I.; et al, 2009. Behavioural Neurology. 175 - 179. 3-4. 21. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-72949094841&partnerID=MN8TOARS . 10.3233/BEN-2009-0238 . Behavioural Neurology
Diagnostic value of CSF protein profile in a Portuguese population of sCJD patients
Baldeiras, I.E.; Ribeiro, M.H.; Pacheco, P.; MacHado, Á.; Santana, I.; Cunha, L.; Oliveira, C.R., 2009. Journal of Neurology. 1540 - 1550. 9. 256. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-69549118450&partnerID=MN8TOARS . 10.1007/s00415-009-5160-0 . Journal of Neurology
Cognitive deficits in middle-aged and older adults with bipolar disorder and cognitive complaints: Comparison with mild cognitive impairment
Silva, D.; Santana, I.; do Couto, F.S.; Maroco, J.; Guerreiro, M.; de Mendonça, A., 2009. International Journal of Geriatric Psychiatry. 624 - 631. 6. 24. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649354789&partnerID=MN8TOARS . 10.1002/gps.2166 . International Journal of Geriatric Psychiatry
Adaptive visual memory reorganization in right medial temporal lobe epilepsy
Figueiredo, P.; Santana, I.; Teixeira, J.; Cunha, C.; Machado, E.; Sales, F.; Almeida, E.; Castelo-Branco, M., 2008. Epilepsia. 1395 - 1408. 8. 49. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-48149087971&partnerID=MN8TOARS . 10.1111/j.1528-1167.2008.01629.x . Epilepsia
Novel progranulin mutation: Screening for PGRN mutations in a Portuguese series of FTD/CBS cases
Guerreiro, R.J.; Santana, I.; Bras, J.M.; Revesz, T.; Rebelo, O.; Ribeiro, M.H.; Santiago, B.; et al, 2008. Movement Disorders. 1269 - 1273. 9. 23. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-51449107701&partnerID=MN8TOARS . 10.1002/mds.22078 . Movement Disorders
Variant Creutzfeldt-Jacob disease: The second case in Portugal and in the same geographical region
Machado, Á.; Soares, H.; Antunes, H.; Magalhães, Z.; Ferreira, C.; Baldeiras, I.; Ribeiro, M.H.; et al, 2008. Journal of Neurology, Neurosurgery and Psychiatry. 180 - 182. 2. 79. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-38849188806&partnerID=MN8TOARS . 10.1136/jnnp.2007.128389 . Journal of Neurology, Neurosurgery and Psychiatry
Peripheral oxidative damage in mild cognitive impairment and mild Alzheimer's disease.
Baldeiras I; Santana I; Proença MT; Garrucho MH; Pascoal R; Rodrigues A; Duro D; Oliveira CR, 2008. 2008. http://europepmc.org/abstract/med/18780972 .
Peripheral oxidative damage in mild cognitive impairment and mild Alzheimer's disease
Baldeiras, I.; Santana, I.; Proença, M.T.; Garrucho, M.H.; Pascoal, R.; Rodrigues, A.; Duro, D.; Oliveira, C.R., 2008. Journal of Alzheimer's Disease. 117 - 128. 1. 15. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-52449117220&partnerID=MN8TOARS . Journal of Alzheimer's Disease
Dementia genetics - A brief review | Genética das demências - Uma breve revisão
Guerreiro, R.J.; Brás, J.M.; Santana, I.; Oliveira, C., 2008. Sinapse. 13 - 20. 1. 8. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-54249130812&partnerID=MN8TOARS . Sinapse
Peripheral inflammatory cytokines as biomarkers in Alzheimer's disease and mild cognitive impairment
Guerreiro, R.J.; Santana, I.; Brás, J.M.; Santiago, B.; Paiva, A.; Oliveira, C., 2007. Neurodegenerative Diseases. 406 - 412. 6. 4. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35048877702&partnerID=MN8TOARS . 10.1159/000107700 . Neurodegenerative Diseases
Association of HFE common mutations with Parkinson's disease, Alzheimer's disease and mild cognitive impairment in a Portuguese cohort
Guerreiro, R.J.; Bras, J.M.; Santana, I.; Januario, C.; Santiago, B.; Morgadinho, A.S.; Ribeiro, M.H.; et al, 2006. BMC Neurology. 6. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747179546&partnerID=MN8TOARS . 10.1186/1471-2377-6-24 . BMC Neurology
Genetic basis of Alzheimer's dementia: Role of mtDNA mutations
Grazina, M.; Pratas, J.; Silva, F.; Oliveira, S.; Santana, I.; Oliveira, C., 2006. Genes, Brain and Behavior. 92 - 107. SUPPL. 2. 5. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646236099&partnerID=MN8TOARS . 10.1111/j.1601-183X.2006.00225.x . Genes, Brain and Behavior
Mitochondrial DNA variants in a Portuguese population of patients with Alzheimer's disease
Grazina, M.; Silva, F.; Santana, I.; Pratas, J.; Santiago, B.; Oliveira, M.; Carreira, I.; Cunha, L.; Oliveira, C., 2005. European Neurology. 121 - 124. 3. 53. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-20844462230&partnerID=MN8TOARS . 10.1159/000085555 . European Neurology
Mitochondria dysfunction of Alzheimer's disease cybrids enhances Aß toxicity
Cardoso, S.M.; Santana, I.; Swerdlow, R.H.; Oliveira, C.R., 2004. Journal of Neurochemistry. 1417 - 1426. 6. 89. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-3042513691&partnerID=MN8TOARS . 10.1111/j.1471-4159.2004.02438.x . Journal of Neurochemistry
Frontotemporal dementia and mitochondrial DNA transitions
Grazina, M.; Silva, F.; Santana, I.; Santiago, B.; Mendes, C.; Simões, M.; Oliveira, M.; Cunha, L.; Oliveira, C., 2004. Neurobiology of Disease. 306 - 311. 2. 15. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1542300730&partnerID=MN8TOARS . 10.1016/j.nbd.2003.11.004 . Neurobiology of Disease
Cytochrome c oxidase is decreased in Alzheimer's disease platelets
Cardoso, S.M.; Proença, M.T.; Santos, S.; Santana, I.; Oliveira, C.R., 2004. Neurobiology of Aging. 105 - 110. 1. 25. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-0348111546&partnerID=MN8TOARS . 10.1016/S0197-4580(03)00033-2 . Neurobiology of Aging
[Cognitive effects of therapy with topiramate in patients with refractory partial epilepsy].
Baeta E; Santana I; Castro G; Gonçalves S; Gonçalves T; Carmo I; Caritas AI, 2002. 2002. http://europepmc.org/abstract/med/12080493 .
Cognitive effects of therapy with topiramate in patients with refractory partial epilepsy | Efectos cognitivos del tratamiento con topiramato en pacientes con epilepsia parcial refractaria
Baeta, E.; Santana, I.; Castro, G.; Gonçalves, S.; Gonçalves, T.; Carmo, I.; Caritas, A.I., 2002. Revista de Neurologia. 737 - 741. 8. 34. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037117438&partnerID=MN8TOARS . Revista de Neurologia
[Malformations in cortical development in patients with epilepsy. Neuroimaging of 17 cases]
Carvalho S; Brito O; Machado E; Santos N; Freitas PM; Bento C; Santana I; Sales F; Martins F, 2001. 2001. http://europepmc.org/abstract/med/11321963 .
Malformations of cortical development in patients with epilepsy: Neuroimaging study of 17 patients | Malformações do desenvolvimento cortical em doentes com epilepsia: Estudo neuroimagiológico de 17 casos
Carvalho, S.; Brito, O.; Machado, E.; Santos, N.; Freitas, P.M.; Bento, C.; Santana, I.; Sales, F.; Martins, F., 2001. Acta Medica Portuguesa. 103 - 106. 1. 14. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346405516&partnerID=MN8TOARS . Acta Medica Portuguesa
Influence of apolipoprotein E genotype on blood redox status of Alzheimer's disease patients.
Fernandes MA; Proenca MT; Nogueira AJ; Grazina MM; Oliveira LM; Fernandes AI; Santiago B; Santana I; Oliveira CR, 1999. 1999. http://europepmc.org/abstract/med/10402486 .
Apolipoprotein E genotype has no effect on the free intracellular Ca2+ concentration of platelets from Alzheimer's disease patients.
Fernandes MA; Proença MT; Nogueira AJ; Oliveira LM; Santiago B; Santana I; Oliveira CR, 1999. 1999. http://europepmc.org/abstract/med/10085419 .
Influence of apolipoprotein E genotype on blood redox status of Alzheimer's disease patients.
Fernandes, M.A.; Proenca, M.T.; Nogueira, A.J.; Grazina, M.M.; Oliveira, L.M.; Fernandes, A.I.; Santiago, B.; Santana, I.; Oliveira, C.R., 1999. International journal of molecular medicine. 179 - 186. 2. 4. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033175761&partnerID=MN8TOARS . International journal of molecular medicine
Effects of apolipoprotein E genotype on blood lipid composition and membrane platelet fluidity in Alzheimer's disease
Fernandes, M.A.S.; Proença, M.T.; Nogueira, A.J.A.; Oliveira, L.M.V.; Santiago, B.; Santana, I.; Oliveira, C.R., 1999. Biochimica et Biophysica Acta - Molecular Basis of Disease. 89 - 96. 1. 1454. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032937469&partnerID=MN8TOARS . 10.1016/S0925-4439(99)00030-7 . Biochimica et Biophysica Acta - Molecular Basis of Disease
Apolipoprotein e genotype has no effect on the free intracellular Ca 2+ concentration of platelets from Alzheimer's disease patients
Fernandes, M.A.S.; Proenca, M.T.; Nogueira, A.J.A.; Oliveira, L.M.V.; Santiago, B.; Santana, I.; Oliveira, C.R., 1999. International Journal of Molecular Medicine. 431 - 434. 4. 3. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033109294&partnerID=MN8TOARS . International Journal of Molecular Medicine
Apolipoprotein E e4 allele is a risk factor for Alzheimer's disease: The central region of Portugal (Coimbra) as a case study
Fernandes, M.A.S.; Oliveira, C.R.; Oliveira, L.M.V.; Nogueira, A.J.A.; Santiago, B.; Santana, I., 1999. European Neurology. 183 - 184. 3. 42. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032589726&partnerID=MN8TOARS . 10.1159/000008098 . European Neurology
Studies of the aluminium effect on superoxide dismutase activity of healthy human erythrocytes and osmotic fragility of erythrocytes in Alzheimer's disease
Fernandes, M.A.S.; Santana, I.; Oliveira, C.R., 1996. Alzheimer's Research. 73 - 78. 3. 2. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030037891&partnerID=MN8TOARS . Alzheimer's Research
Frontal lobe-type dementia associated with motor neuron disease | Demencia do tipo frontal associada a doenca do neuronio motor.
Santana, I.; Macario, M.C.; Rebelo, O.; Pires, M.M., 1995. Acta médica portuguesa. 629 - 634. 11. 8. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029399649&partnerID=MN8TOARS . Acta médica portuguesa
[Frontal lobe-type dementia associated with motor neuron disease]
Santana I; Macario MC; Rebelo O; Pires MM, 1995. 1995. http://europepmc.org/abstract/med/8713508 .
Decreased superoxide dismutase activity in erythrocytes from patients with Alzheimer's disease
Fernandes, M.A.S.; Santana, I.; Januario, C.; Cunha, L.; Oliveira, C.R., 1993. Medical Science Research. 679 - 682. 18. 21. 1993. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027366364&partnerID=MN8TOARS . Medical Science Research
5 307 out of 307 Publications
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