João Malva

Methylmercury Interactions With Gut Microbiota and Potential Modulation of Neurogenic Niches in the Brain.

Pinto DV; Raposo RS; Matos GA; Alvarez-Leite JI; Malva JO; Oriá RB, Frontiers in neuroscience. 2020. http://europepmc.org/abstract/med/33224022 . 10.3389/fnins.2020.576543 . Frontiers in neuroscience

Methylmercury Impact on Adult Neurogenesis: Is the Worst Yet to Come From Recent Brazilian Environmental Disasters?

Raposo RDS; Pinto DV; Moreira R; Dias RP; Fontes Ribeiro CA; Oriá RB; Malva JO, Frontiers in aging neuroscience. 2020. http://europepmc.org/abstract/med/33328968 . 10.3389/fnagi.2020.591601 . Frontiers in aging neuroscience

ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice.

Bousquet J; Anto JM; Bachert C; Haahtela T; Zuberbier T; Czarlewski W; Bedbrook A; et al, Allergy. 2020. http://europepmc.org/abstract/med/32512619 . 10.1111/all.14422 . Allergy

Advancing tools to promote health equity across European Union regions: the EURO-HEALTHY project.

Santana P; Freitas Â; Stefanik I; Costa C; Oliveira M; Rodrigues TC; Vieira A; et al, Health research policy and systems. 2020. http://europepmc.org/abstract/med/32054540 . 10.1186/s12961-020-0526-y . Health research policy and systems

Correlation between work impairment, scores of rhinitis severity and asthma using the MASK-air® App.

Bédard A; Antó JM; Fonseca JA; Arnavielhe S; Bachert C; Bedbrook A; Bindslev-Jensen C; et al, Allergy. 2020. http://europepmc.org/abstract/med/31995656 . 10.1111/all.14204 . Allergy

Calcium Signaling in Aging and Neurodegenerative Diseases 2019.

Cortes L; Malva J; Rego AC; Pereira CF, International journal of molecular sciences. 2020. http://europepmc.org/abstract/med/32046230 . 10.3390/ijms21031125 . International journal of molecular sciences

Editorial: Interplay Between Nutrition, the Intestinal Microbiota and the Immune System.

Oriá RB; Empadinhas N; Malva JO, Frontiers in immunology. 2020. http://europepmc.org/abstract/med/32849628 . 10.3389/fimmu.2020.01758 . Frontiers in immunology

Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 1)

Bousquet, Jean; Pham-Thi, Nhân; Bedbrook, Anna; Agache, Ioana; Annesi-Maesano, Isabella; Ansotegui, Ignacio; Anto, Josep M; et al, 2019. http://hdl.handle.net/10400.6/9366 . 10.21037/jtd.2019.08.64 .

Development of a Healthy Lifestyle Assessment Toolkit for the General Public.

Reis F; Sá-Moura B; Guardado D; Couceiro P; Catarino L; Mota-Pinto A; Veríssimo MT; et al, Frontiers in medicine. 2019. http://europepmc.org/abstract/med/31316985 . 10.3389/fmed.2019.00134 . Frontiers in medicine

Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study.

Bédard A; Basagaña X; Anto JM; Garcia-Aymerich J; Devillier P; Arnavielhe S; Bedbrook A; et al, The Journal of allergy and clinical immunology. 2019. http://europepmc.org/abstract/med/30951790 . 10.1016/j.jaci.2019.01.053 . The Journal of allergy and clinical immunology

Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma.

Bousquet J; Bedbrook A; Czarlewski W; Onorato GL; Arnavielhe S; Laune D; Mathieu-Dupas E; et al, Clinical and translational allergy. 2019. http://europepmc.org/abstract/med/30911372 . 10.1186/s13601-019-0252-0 . Clinical and translational allergy

Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study.

Menditto E; Costa E; Midão L; Bosnic-Anticevich S; Novellino E; Bialek S; Briedis V; et al, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2019. http://europepmc.org/abstract/med/30597673 . 10.1111/cea.13333 . Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

Adult Hippocampal Neurogenesis in Different Taxonomic Groups: Possible Functional Similarities and Striking Controversies.

Augusto-Oliveira M; Arrifano GPF; Malva JO; Crespo-Lopez ME, Cells. 2019. http://europepmc.org/abstract/med/30764477 . 10.3390/cells8020125 . Cells

The Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing.

Bousquet J; Illario M; Farrell J; Batey N; Carriazo AM; Malva J; Hajjam J; et al, Translational medicine @ UniSa. 2019. http://europepmc.org/abstract/med/31360670 . Translational medicine @ UniSa

Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases

Bousquet, J Jean; Schünemann, Holger J; Togias, Alkis; Erhola, Marina; Hellings, Peter W; Zuberbier, Torsten; Agache, Ioana; et al, 2019. http://hdl.handle.net/10400.6/9365 . 10.1186/s13601-019-0279-2 .

ARIA pharmacy 2018: Allergic rhinitis care pathways for community pharmacy

Bosnic-Anticevich, Sinthia; Costa, Elisio; Menditto, Enrica; Lourenço, Olga; Novellino, Ettore; Bialek, Slawomir; Briedis, Vitalis; et al, 2019. http://hdl.handle.net/10400.6/9359 . 10.1111/all.13701 .

What Do Microglia Really Do in Healthy Adult Brain?

Marcus Oliveira; Gabriela Arrifano; Amanda Lopes-Araújo; Leticia Santos-Sacramento; Priscila Y. Takeda; Anthony DC; João O. Malva; Maria Elena Crespo-Lopez, Cells. 2019. https://www.mdpi.com/2073-4409/8/10/1293 . 10.3390/cells8101293 . Cells

Transfer of innovation on allergic rhinitis and asthma multimorbidity in the elderly (MACVIA-ARIA) - EIP on AHA Twinning Reference Site (GARD research demonstration project).

Bousquet J; Agache I; Aliberti MR; Angles R; Annesi-Maesano I; Anto JM; Arnavielhe S; et al, Allergy. 2018. http://europepmc.org/abstract/med/28600902 . 10.1111/all.13218 . Allergy

MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence.

Bousquet J; Arnavielhe S; Bedbrook A; Bewick M; Laune D; Mathieu-Dupas E; Murray R; et al, Clinical and translational allergy. 2018. http://europepmc.org/abstract/med/30386555 . 10.1186/s13601-018-0227-6 . Clinical and translational allergy

Revisiting Inbred Mouse Models to Study the Developing Brain: The Potential Role of Intestinal Microbiota.

Oriá RB; Malva JO; Foley PL; Freitas RS; Bolick DT; Guerrant RL, Frontiers in Human Neuroscience. 2018. http://europepmc.org/abstract/med/30283311 . 10.3389/fnhum.2018.00358 . Frontiers in Human Neuroscience

Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology.

Bousquet J; Hellings PW; Agache I; Amat F; Annesi-Maesano I; Ansotegui IJ; Anto JM; et al, The Journal of allergy and clinical immunology. 2018. http://europepmc.org/abstract/med/30273709 . 10.1016/j.jaci.2018.08.049 . The Journal of allergy and clinical immunology

Geolocation with respect to personal privacy for the Allergy Diary app - a MASK study.

Samreth D; Arnavielhe S; Ingenrieth F; Bedbrook A; Onorato GL; Murray R; Almeida R; et al, The World Allergy Organization Journal. 2018. http://europepmc.org/abstract/med/30061979 . 10.1186/s40413-018-0194-3 . The World Allergy Organization Journal

A case study of polypharmacy management in nine European countries: Implications for change management and implementation.

McIntosh J; Alonso A; MacLure K; Stewart D; Kempen T; Mair A; Castel-Branco M; et al, PloS one. 2018. http://europepmc.org/abstract/med/29668763 . 10.1371/journal.pone.0195232 . PloS one

Effect of Hypoproteic and High-Fat Diets on Hippocampal Blood-Brain Barrier Permeability and Oxidative Stress.

de Aquino CC; Leitão RA; Oliveira Alves LA; Coelho-Santos V; Guerrant RL; Ribeiro CF; Malva JO; Silva AP; Oriá RB, Frontiers in nutrition. 2018. http://europepmc.org/abstract/med/30687711 . 10.3389/fnut.2018.00131 . Frontiers in nutrition

The Quadruple Helix-Based Innovation Model of Reference Sites for Active and Healthy Ageing in Europe: The Ageing@Coimbra Case Study.

Malva JO; Amado A; Rodrigues A; Mota-Pinto A; Cardoso AF; Teixeira AM; Todo-Bom A; et al, Frontiers in medicine. 2018. http://europepmc.org/abstract/med/29868588 . 10.3389/fmed.2018.00132 . Frontiers in medicine

CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis: a SUNFRAIL report.

Bousquet J; Onorato GL; Bachert C; Barbolini M; Bedbrook A; Bjermer L; de Sousa JC; et al, Clinical and translational allergy. 2017. http://europepmc.org/abstract/med/29075437 . 10.1186/s13601-017-0173-8 . Clinical and translational allergy

Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis - A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement.

Hellings PW; Fokkens WJ; Bachert C; Akdis CA; Bieber T; Agache I; Bernal-Sprekelsen M; et al, Allergy. 2017. http://europepmc.org/abstract/med/28306159 . 10.1111/all.13162 . Allergy

Validation of the MASK-rhinitis visual analogue scale on smartphone screens to assess allergic rhinitis control.

Caimmi D; Baiz N; Tanno LK; Demoly P; Arnavielhe S; Murray R; Bedbrook A; et al, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2017. http://europepmc.org/abstract/med/28886234 . 10.1111/cea.13025 . Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

Silencing of P2X7R by RNA interference in the hippocampus can attenuate morphological and behavioral impact of pilocarpine-induced epilepsy.

Amorim RP; Araújo MGL; Valero J; Lopes-Cendes I; Pascoal VDB; Malva JO; da Silva Fernandes MJ, Purinergic Signalling. 2017. http://europepmc.org/abstract/med/28707031 . 10.1007/s11302-017-9573-4 . Purinergic Signalling

Impact of Neuroinflammation on Hippocampal Neurogenesis: Relevance to Aging and Alzheimer's Disease.

Valero J; Bernardino L; Cardoso FL; Silva AP; Fontes-Ribeiro C; Ambrósio AF; Malva JO, Journal of Alzheimer's disease : JAD. 2017. http://europepmc.org/abstract/med/28671124 . 10.3233/jad-170239 . Journal of Alzheimer's disease : JAD

Building Bridges for Innovation in Ageing: Synergies between Action Groups of the EIP on AHA.

Bousquet J; Bewick M; Cano A; Eklund P; Fico G; Goswami N; Guldemond NA; et al, 2017. http://europepmc.org/abstract/med/27999855 . 10.1007/s12603-016-0803-1 .

Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

Bousquet J; Farrell J; Crooks G; Hellings P; Bel EH; Bewick M; Chavannes NH; et al, 2017. http://europepmc.org/abstract/med/28239450 . 10.1186/s13601-016-0135-6 .

A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people.

Stewart D; Gibson-Smith K; MacLure K; Mair A; Alonso A; Codina C; Cittadini A; et al, PloS one. 2017. http://europepmc.org/abstract/med/29155870 . 10.1371/journal.pone.0188348 . PloS one

Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

Bousquet J; Farrell J; Crooks G; Hellings P; Bel EH; Bewick M; Chavannes NH; et al, 2016. http://europepmc.org/abstract/med/27478588 . 10.1186/s13601-016-0116-9 .

Operational definition of active and healthy ageing: Roadmap from concept to change of management.

Malva JO; Bousquet J, 2016. http://europepmc.org/abstract/med/26704254 . 10.1016/j.maturitas.2015.11.004 .

ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle.

Bousquet J; Hellings PW; Agache I; Bedbrook A; Bachert C; Bergmann KC; Bewick M; et al, 2016. http://europepmc.org/abstract/med/28050247 . 10.1186/s13601-016-0137-4 .

Coxsackievirus Adenovirus Receptor Loss Impairs Adult Neurogenesis, Synapse Content, and Hippocampus Plasticity.

Zussy C; Loustalot F; Junyent F; Gardoni F; Bories C; Valero J; Desarménien MG; et al, 2016. http://europepmc.org/abstract/med/27629708 . 10.1523/jneurosci.0132-16.2016 .

Should we use gait speed in COPD, FEV1 in frailty and dyspnoea in both?

Bousquet J; Dinh-Xuan AT; Similowski T; Malva J; Ankri J; Barbagallo M; Fabbri L; et al, 2016. http://europepmc.org/abstract/med/27478189 . 10.1183/13993003.00633-2016 .

Operational Definition of Active and Healthy Aging (AHA): The European Innovation Partnership (EIP) on AHA Reference Site Questionnaire: Montpellier October 20-21, 2014, Lisbon July 2, 2015.

Bousquet J; Malva J; Nogues M; Mañas LR; Vellas B; Farrell J; MACVIA Research Group, 2015. http://europepmc.org/abstract/med/26498697 . 10.1016/j.jamda.2015.09.004 .

Operational Definition of Active and Healthy Ageing (AHA): A Conceptual Framework.

Bousquet J; Kuh D; Bewick M; Standberg T; Farrell J; Pengelly R; Joel ME; et al, 2015. http://europepmc.org/abstract/med/26482699 . 10.1007/s12603-015-0589-6 .

Portugal at the cross road of international chronic respiratory programmes.

Bousquet J; Pinto JR; Barbara C; da Sousa JC; Fonseca J; Miguel JP; Boavida J; et al, 2015. http://europepmc.org/abstract/med/26275595 . 10.1016/j.rppnen.2015.07.001 .

New insights into the role of histamine in subventricular zone-olfactory bulb neurogenesis.

Eiriz MF; Valero J; Malva JO; Bernardino L, 2014. http://europepmc.org/abstract/med/24982610 . 10.3389/fnins.2014.00142 .

Growth hormone pathways signaling for cell proliferation and survival in hippocampal neural precursors from postnatal mice.

Devesa P; Agasse F; Xapelli S; Almengló C; Devesa J; Malva JO; Arce VM, 2014. http://europepmc.org/abstract/med/25156632 . 10.1186/1471-2202-15-100 .

Modulation of subventricular zone oligodendrogenesis: a role for hemopressin?

Xapelli S; Agasse F; Grade S; Bernardino L; Ribeiro FF; Schitine CS; Heimann AS; et al, 2014. http://europepmc.org/abstract/med/24578683 . 10.3389/fncel.2014.00059 .

Can we talk about microglia without neurons? A discussion of microglial cell autonomous properties in culture.

Neiva I; Malva JO; Valero J, 2014. http://europepmc.org/abstract/med/25104923 . 10.3389/fncel.2014.00202 .

Long-term effects of an acute and systemic administration of LPS on adult neurogenesis and spatial memory.

Valero J; Mastrella G; Neiva I; Sánchez S; Malva JO, 2014. http://europepmc.org/abstract/med/24795557 . 10.3389/fnins.2014.00083 .

Activation of Type 1 Cannabinoid Receptor (CB1R) promotes neurogenesis in murine subventricular zone cell cultures

Xapelli, Sara; Agasse, Fabienne; Sarda-Arroyo, Laura; Bernardino, Liliana; Santos, Tiago; Ribeiro, Filipa F.; Valero, Jorge; et al, 2013. http://hdl.handle.net/10400.1/11739 . 10.1371/journal.pone.0063529 .

Oligodendrogenesis from neural stem cells: Perspectives for remyelinating strategies.

Grade S; Bernardino L; Malva JO, 2013. http://europepmc.org/abstract/med/23340483 . 10.1016/j.ijdevneu.2013.01.004 .

Galanin promotes neuronal differentiation in murine subventricular zone cell cultures.

Agasse F; Xapelli S; Coronas V; Christiansen SH; Rosa AI; Sardá-Arroyo L; Santos T; et al, 2013. http://europepmc.org/abstract/med/23327619 . 10.1089/scd.2012.0161 .

Brain-derived neurotrophic factor promotes vasculature-associated migration of neuronal precursors toward the ischemic striatum.

Grade S; Weng YC; Snapyan M; Kriz J; Malva JO; Saghatelyan A, 2013. http://europepmc.org/abstract/med/23383048 . 10.1371/journal.pone.0055039 .

Histamine stimulates neurogenesis in the rodent subventricular zone

Bernardino, Liliana; Eiriz, Maria Francisca; Santos, Tiago; Xapelli, Sara; Grade, Sofia; Rosa, Alexandra Isabel; Cortes, Luisa; et al, 2012. http://hdl.handle.net/10400.1/11105 . 10.1002/stem.1042 .

Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures.

Baptista S; Bento AR; Gonçalves J; Bernardino L; Summavielle T; Lobo A; Fontes-Ribeiro C; et al, 2012. http://europepmc.org/abstract/med/22381583 . 10.1016/j.neuropharm.2012.02.015 .

The effect of methamphetamine on subventricular zone neurogenesis: Cell death, proliferation and differentiation

Bento, A.R.; Baptista, S.; Malva, J.O.; Silva, A.P.; Agasse, F., 2012 IEEE 2nd Portuguese Meeting in Bioengineering, ENBENG 2012. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869407710&partnerID=MN8TOARS . 10.1109/ENBENG.2012.6331378 . 2012 IEEE 2nd Portuguese Meeting in Bioengineering, ENBENG 2012

Neuropeptide Y inhibits interleukin-1 beta-induced microglia motility.

Ferreira R; Santos T; Cortes L; Cochaud S; Agasse F; Silva AP; Xapelli S; et al, 2012. http://europepmc.org/abstract/med/22007767 . 10.1111/j.1471-4159.2011.07541.x .

Functional identification of neural stem cell-derived oligodendrocytes.

Grade S; Agasse F; Bernardino L; Malva JO; Silva CG; Cortes L; Eiriz, M.F.; et al, Current Stem Cell Research and Therapy. 288 - 296. 3. 6. 2012. http://europepmc.org/abstract/med/22610560 . 10.1007/978-1-61779-815-3_11 . Current Stem Cell Research and Therapy

Multifaces of neuropeptide Y in the brain - Neuroprotection, neurogenesis and neuroinflammation

Malva, J.O.; Xapelli, S.; Baptista, S.; Valero, J.; Agasse, F.; Ferreira, R.; Silva, A.P., Neuropeptides. 299 - 308. 6. 46. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869883047&partnerID=MN8TOARS . 10.1016/j.npep.2012.09.001 . Neuropeptides

Polymeric nanoparticles to control the differentiation of neural stem cells in the subventricular zone of the brain.

Santos T; Ferreira R; Maia J; Agasse F; Xapelli S; Cortes L; Bragança J; et al, 2012. http://europepmc.org/abstract/med/23176155 . 10.1021/nn304541h .

Methamphetamine-induced changes in the mice hippocampal neuropeptide Y system: implications for memory impairment.

Gonçalves J; Baptista S; Olesen MV; Fontes-Ribeiro C; Malva JO; Woldbye DP; Silva AP, 2012. http://europepmc.org/abstract/med/23061411 . 10.1111/jnc.12052 .

Protective role of neuropeptide Y Y2 receptors in cell death and microglial response following methamphetamine injury.

Gonçalves J; Ribeiro CF; Malva JO; Silva AP, 2012. http://europepmc.org/abstract/med/22805317 . 10.1111/j.1460-9568.2012.08232.x .

Ampakine CX546 increases proliferation and neuronal differentiation in subventricular zone stem/progenitor cell cultures.

Schitine C; Xapelli S; Agasse F; Sardà-Arroyo L; Silva AP; De Melo Reis RA; de Mello FG; Malva JO, 2012. http://europepmc.org/abstract/med/22506985 . 10.1111/j.1460-9568.2012.08072.x .

Controlling the neuronal differentiation of stem cells by the intracellular delivery of retinoic acid-loaded nanoparticles.

Maia J; Santos T; Aday S; Agasse F; Cortes L; Malva JO; Bernardino L; Ferreira L, 2011. http://europepmc.org/abstract/med/21171566 . 10.1021/nn101724r .

Functional Identification of Cell Phenotypes Differentiating from Mice Retinal Neurospheres Using Single Cell Calcium Imaging

De Melo Reis, R.A.; Schitine, C.S.; Kofalvi, A.; Grade, S.; Cortes, L.; Gardino, P.F.; Malva, J.O.; de Mello, F.G., Cellular and Molecular Neurobiology. 1 - 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952606231&partnerID=MN8TOARS . 10.1007/s10571-011-9673-6 . Cellular and Molecular Neurobiology

Functional identification of cell phenotypes differentiating from mice retinal neurospheres using single cell calcium imaging.

De Melo Reis, R.A.; Schitine, C.S.; Köfalvi, A.; Grade, S.; Cortes, L.; Gardino, P.F.; Malva, J.O.; de Mello, F.G., Cellular and molecular neurobiology. 835 - 846. 6. 31. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856384867&partnerID=MN8TOARS . Cellular and molecular neurobiology

Methamphetamine exerts toxic effects on subventricular zone stem/progenitor cells and inhibits neuronal differentiation.

Bento AR; Baptista S; Malva JO; Silva AP; Agasse F, 2011. http://europepmc.org/abstract/med/21453012 . 10.1089/rej.2010.1109 .

NPY promotes chemokinesis and neurogenesis in the rat subventricular zone.

Thiriet N; Agasse F; Nicoleau C; Guégan C; Vallette F; Cadet JL; Jaber M; Malva JO; Coronas V, 2011. http://europepmc.org/abstract/med/21175616 . 10.1111/j.1471-4159.2010.07154.x .

Methamphetamine-induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin

Faculdade de Ciências, 2010. https://repositorio-aberto.up.pt/handle/10216/91224 . 10.1111/j.1460-9568.2009.07059.x .

Neuropeptide Y modulation of interleukin-1{beta} (IL-1{beta})-induced nitric oxide production in microglia.

Ferreira R; Xapelli S; Santos T; Silva AP; Cristóvão A; Cortes L; Malva JO, 2010. http://europepmc.org/abstract/med/20959451 . 10.1074/jbc.M110.164020 .

Brain injury associated with widely abused amphetamines: neuroinflammation, neurogenesis and blood-brain barrier.

Silva AP; Martins T; Baptista S; Gonçalves J; Agasse F; Malva JO, 2010. http://europepmc.org/abstract/med/21208167 .

The angiogenic factor angiopoietin-1 is a proneurogenic peptide on subventricular zone stem/progenitor cells.

Rosa AI; Gonçalves J; Cortes L; Bernardino L; Malva JO; Agasse F, 2010. http://europepmc.org/abstract/med/20357108 . 10.1523/JNEUROSCI.5597-09.2010 .

Brain Injury Associated With Widely Abused Amphetamines: Neuroinflammation, Neurogenesis And Blood-Brain Barrier

Silva, A.P.; Martins, T.; Baptista, S.; Gonçalves, J.; Agasse, F.; Malva, J.O., Current Drug Abuse Reviews. 239 - 254. 4. 3. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-79551645771&partnerID=MN8TOARS . Current Drug Abuse Reviews

Biapigenin modulates the activity of the adenine nucleotide translocator in isolated rat brain mitochondria.

Silva BA; Oliveira PJ; Cristóvão A; Dias AC; Malva JO, 2010. http://europepmc.org/abstract/med/19597902 . 10.1007/s12640-009-9082-5 .

Transthyretin knockout mice display decreased susceptibility to AMPA-induced neurodegeneration.

Nunes AF; Montero M; Franquinho F; Santos SD; Malva J; Zimmer J; Sousa MM, 2009. http://europepmc.org/abstract/med/19595729 . 10.1016/j.neuint.2009.07.001 .

Effects of Starch/ Polycaprolactone-based Blends for Spinal Cord Injury Regeneration in Neurons/Glial Cells Viability and Proliferation

Salgado, A.J.; Sousa, R.A.; Fraga, J.S.; Pego, J.M.; Silva, B.A.; Malva, J.O.; Neves, N.M.; Reis, R.L.; Sousa, N., Journal of Bioactive and Compatible Polymers. 235 - 248. 3. 24. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-65649101219&partnerID=MN8TOARS . 10.1177/0883911509104081 . Journal of Bioactive and Compatible Polymers

Tumor necrosis factor-alpha modulates survival, proliferation, and neuronal differentiation in neonatal subventricular zone cell cultures.

Bernardino L; Agasse F; Silva B; Ferreira R; Grade S; Malva JO; Bernardino, Liliana; et al, 2008. http://europepmc.org/abstract/med/18583543 . 10.1634/stemcells.2007-0914 .

Methamphetamine-induced early increase of IL-6 and TNF-alpha mRNA expression in the mouse brain.

Gonçalves J; Martins T; Ferreira R; Milhazes N; Borges F; Ribeiro CF; Malva JO; Macedo TR; Silva AP, 2008. http://europepmc.org/abstract/med/18991854 . 10.1196/annals.1432.043 .

Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X7 receptor-mediated IL-1beta release.

Bernardino L; Balosso S; Ravizza T; Marchi N; Ku G; Randle JC; Malva JO; et al, 2008. http://europepmc.org/abstract/med/18384650 . 10.1111/j.1471-4159.2008.05387.x .

Neuropeptide Y promotes neurogenesis in murine subventricular zone.

Agasse F; Bernardino L; Kristiansen H; Christiansen SH; Ferreira R; Silva B; Grade S; Woldbye DP; Malva JO, 2008. http://europepmc.org/abstract/med/18388302 . 10.1634/stemcells.2008-0056 .

Response to histamine allows the functional identification of neuronal progenitors, neurons, astrocytes, and immature cells in subventricular zone cell cultures.

Agasse F; Bernardino L; Silva B; Ferreira R; Grade S; Malva JO, 2008. http://europepmc.org/abstract/med/18279032 . 10.1089/rej.2007.0600 .

Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: A role for microglia

Xapelli, S.; Bernardino, L.; Ferreira, R.; Grade, S.; Silva, A.P.; Salgado, J.R.; Cavadas, C.; et al, European Journal of Neuroscience. 2089 - 2102. 8. 27. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-42049112780&partnerID=MN8TOARS . 10.1111/j.1460-9568.2008.06172.x . European Journal of Neuroscience

Quercetin, kaempferol and biapigenin from hypericum perforatum are neuroprotective against excitotoxic insults

Silva, B.; Oliveira, P.J.; Dias, A.; Malva, J.O., Neurotoxicity Research. 265 - 279. 3-4. 13. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-55249095521&partnerID=MN8TOARS . 10.1007/BF03033510 . Neurotoxicity Research

St. John's Wort (Hypericum perforatum) extracts and isolated phenolic compounds are effective antioxidants in several in vitro models of oxidative stress

Silva, B.A.; Malva, J.O.; Dias, A.C.P., Food Chemistry. 611 - 619. 3. 110. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-42649099265&partnerID=MN8TOARS . 10.1016/j.foodchem.2008.02.047 . Food Chemistry

GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses.

Pinheiro PS; Perrais D; Coussen F; Barhanin J; Bettler B; Mann JR; Malva JO; Heinemann SF; Mulle C, 2007. http://europepmc.org/abstract/med/17620617 . 10.1073/pnas.0608891104 .

Neuropeptide Y can rescue neurons from cell death following the application of an excitotoxic insult with kainate in rat organotypic hippocampal slice cultures

Xapelli, S.; Silva, A.P.; Ferreira, R.; Malva, J.O., Peptides. 288 - 294. 2. 28. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846629106&partnerID=MN8TOARS . 10.1016/j.peptides.2006.09.031 . Peptides

Susceptibility of hippocampal neurons to Aß peptide toxicity is associated with perturbation of Ca2+ homeostasis

Resende, R.; Pereira, C.; Agostinho, P.; Vieira, A.P.; Malva, J.O.; Oliveira, C.R., Brain Research. 11 - 21. 1. 1143. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947303240&partnerID=MN8TOARS . 10.1016/j.brainres.2007.01.071 . Brain Research

Protein kinase C activity blocks neuropeptide Y-mediated inhibition of glutamate release and contributes to excitability of the hippocampus in status epilepticus.

Silva AP; Lourenço J; Xapelli S; Ferreira R; Kristiansen H; Woldbye DP; Oliveira CR; Malva JO, 2007. http://europepmc.org/abstract/med/17167071 . 10.1096/fj.06-6163com .

Mitochondria as targets for neuronal protection against excitotoxicity: A role for phenolic compounds?

Silva, B.A.; Oliveira, P.J.; Dias, A.C.P.; Malva, J.O., Central Nervous System Agents in Medicinal Chemistry. 205 - 222. 3. 7. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548408654&partnerID=MN8TOARS . 10.2174/187152407781669152 . Central Nervous System Agents in Medicinal Chemistry

Neuropeptide Y as an endogenous antiepileptic, neuroprotective and pro-neurogenic peptide.

Xapelli S; Agasse F; Ferreira R; Silva AP; Malva JO, 2006. http://europepmc.org/abstract/med/18221213 . 10.2174/157488906778773689 .

Inactivation of caspase-1 in rodent brain: A novel anticonvulsive strategy

Ravizza, T.; Lucas, S.-M.; Balosso, S.; Bernardino, L.; Ku, G.; Noé, F.; Malva, J.; et al, Epilepsia. 1160 - 1168. 7. 47. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746145901&partnerID=MN8TOARS . 10.1111/j.1528-1167.2006.00590.x . Epilepsia

Inflammation and neurogenesis in temporal lobe epilepsy

Bernardino, L.; Ferreira, R.; Cristóvão, A.J.; Sales, F.; Malva, J.O., Current Drug Targets: CNS and Neurological Disorders. 349 - 360. 4. 4. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23144431758&partnerID=MN8TOARS . 10.2174/1568007054546171 . Current Drug Targets: CNS and Neurological Disorders

Proteolysis of NR2B by calpain in the hippocampus of epileptic rats.

Araújo IM; Xapelli S; Gil JM; Mohapel P; Petersén A; Pinheiro PS; Malva JO; et al, 2005. http://europepmc.org/abstract/med/15729144 . 10.1097/00001756-200503150-00017 .

Editorial

Malva, J.O., Current Drug Targets: CNS and Neurological Disorders. 4. 4. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23144460680&partnerID=MN8TOARS . 10.2174/1568007054546135 . Current Drug Targets: CNS and Neurological Disorders

Presynaptic kainate receptors are localized close to release sites in rat hippocampal synapses

Pinheiro, P.S.; Rodrigues, R.J.; Rebola, N.; Xapelli, S.; Oliveira, C.R.; Malva, J.O., Neurochemistry International. 309 - 316. 5. 47. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-22044433723&partnerID=MN8TOARS . 10.1016/j.neuint.2005.05.007 . Neurochemistry International

Phytochemical and antioxidant characterization of Hypericum perforatum alcoholic extracts

Silva, B.A.; Ferreres, F.; Malva, J.O.; Dias, A.C.P., Food Chemistry. 157 - 167. 1-2. 90. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-4644274688&partnerID=MN8TOARS . 10.1016/j.foodchem.2004.03.049 . Food Chemistry

Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats.

Silva AP; Xapelli S; Pinheiro PS; Ferreira R; Lourenço J; Cristóvão A; Grouzmann E; et al, 2005. http://europepmc.org/abstract/med/15773916 . 10.1111/j.1471-4159.2004.03005.x .

Neuroprotective effect of H. perforatum extracts on beta-amyloid-induced neurotoxicity.

Silva BA; Dias AC; Ferreres F; Malva JO; Oliveira CR, 2004. http://europepmc.org/abstract/med/15325964 . 10.1007/BF03033214 .

Neuroprotective properties of Valeriana officinalis extracts.

Malva JO; Santos S; Macedo T, 2004. http://europepmc.org/abstract/med/15325965 . 10.1007/BF03033215 .

Presynaptic kainate receptors modulating glutamatergic transmission in the rat hippocampus are inhibited by arachidonic acid.

Cunha RA; Ribeiro JA; Malva JO, 2004. http://europepmc.org/abstract/med/14643755 . 10.1016/S0197-0186(03)00167-0 .

Neurotoxicity induced by antiepileptic drugs in cultured hippocampal neurons: a comparative study between carbamazepine, oxcarbazepine, and two new putative antiepileptic drugs, BIA 2-024 and BIA 2-093.

Araújo IM; Ambrósio AF; Leal EC; Verdasca MJ; Malva JO; Soares-da-Silva P; Carvalho AP; Carvalho CM, 2004. http://europepmc.org/abstract/med/15571507 . 10.1111/j.0013-9580.2004.14104.x .

Understanding the physiology of glutamate receptors by use of a protocol for neuronal staining

Malva, J.O.; Vieira, A.P.; Oliveira, C.R.; Malva JO; Vieira AP; Oliveira CR, American Journal of Physiology - Advances in Physiology Education. 78 - 85. 1-4. 27. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346502965&partnerID=MN8TOARS . American Journal of Physiology - Advances in Physiology Education

Functional interaction between neuropeptide Y receptors and modulation of calcium channels in the rat hippocampus.

Silva AP; Carvalho AP; Carvalho CM; Malva JO, 2003. http://europepmc.org/abstract/med/12623227 . 10.1016/S0028-3908(02)00382-9 .

Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures.

Rego AC; Monteiro NM; Silva AP; Gil J; Malva JO; Oliveira CR, 2003. http://europepmc.org/abstract/med/12887678 . 10.1046/j.1471-4159.2003.01898.x .

Presynaptic modulation controlling neuronal excitability and epileptogenesis: role of kainate, adenosine and neuropeptide Y receptors.

Malva JO; Silva AP; Cunha RA, 2003. http://europepmc.org/abstract/med/14570395 . 10.1023/A:1025618324593 .

Subcellular localization of adenosine A(1) receptors in nerve terminals and synapses of the rat hippocampus.

Rebola N; Pinheiro PC; Oliveira CR; Malva JO; Cunha RA, 2003. http://europepmc.org/abstract/med/14499945 . 10.1016/S0006-8993(03)03247-5 .

Activation of neuropeptide Y receptors is neuroprotective against excitotoxicity in organotypic hippocampal slice cultures

Silva, Ana P.; Pinheiro, Paulo S.; Carvalho, Arsélio P.; Carvalho, Caetana M.; Jakobsen, Birthe; Zimmer, Jens; Malva, João O.; et al, 2003. http://hdl.handle.net/10316/12831 . 10.1523/JNEUROSCI.1510-05.2005 .

Cobalt staining of hippocampal neurons mediated by non-desensitizing activation of AMPA but not kainate receptors.

Malva JO; Vieira AP; Ambrósio AF; Oliveira CR, 2003. http://europepmc.org/abstract/med/12858045 . 10.1097/00001756-200305060-00014 .

Solubilization and immunological identification of presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in the rat hippocampus.

Pinheiro PS; Rodrigues RJ; Silva AP; Cunha RA; Oliveira CR; Malva JO, 2003. http://europepmc.org/abstract/med/12499049 . 10.1016/S0304-3940(02)01217-X .

Role of kainate receptor activation and desensitization on the [Ca2+]i changes in cultured rat hippocampal neurons

Silva, A.P.; Malva, J.O.; Ambrósio, A.F.; Salgado, A.J.; Carvalho, A.P.; Carvalho, C.M., Journal of Neuroscience Research. 378 - 386. 5. 65. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035448626&partnerID=MN8TOARS . 10.1002/jnr.1164 . Journal of Neuroscience Research

Inhibition of glutamate release by BIA 2-093 and BIA 2-024, two novel derivatives of carbamazepine, due to blockade of sodium but not calcium channels

Ambrósio, A.F.; Silva, A.P.; Malva, J.O.; Soares-da-Silva, P.; Carvalho, A.P.; Carvalho, C.M., Biochemical Pharmacology. 1271 - 1275. 10. 61. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035873841&partnerID=MN8TOARS . 10.1016/S0006-2952(01)00584-6 . Biochemical Pharmacology

Presynaptic N-methyl-D-aspartate receptor activation inhibits neurotransmitter release through nitric oxide formation in rat hippocampal nerve terminals

Sequeira, S.M.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., Molecular Brain Research. 111 - 118. 1-2. 89. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035906241&partnerID=MN8TOARS . 10.1016/S0169-328X(01)00069-9 . Molecular Brain Research

Modulation of intracellular calcium changes and glutamate release by neuropeptide Y1 and Y2 receptors in the rat hippocampus: Differential effects in CA1, CA3 and dentate gyrus

Silva, A.P.; Carvalho, A.P.; Carvalho, C.M.; Malva, J.O., Journal of Neurochemistry. 286 - 296. 2. 79. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034770180&partnerID=MN8TOARS . 10.1046/j.1471-4159.2001.00560.x . Journal of Neurochemistry

Neurotoxic/neuroprotective profile of carbamazepine, oxcarbazepine and two new putative antiepileptic drugs, BIA 2-093 and BIA 2-024

Ambrósio, A.F.; Silva, A.P.; Araújo, I.; Malva, J.O.; Soares-da-Silva, P.; Carvalho, A.P.; Carvalho, C.M., European Journal of Pharmacology. 191 - 201. 2. 406. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034644868&partnerID=MN8TOARS . 10.1016/S0014-2999(00)00659-2 . European Journal of Pharmacology

Pertussis toxin prevents presynaptic inhibition by kainate receptors of rat hippocampal [3H]GABA release

A. Cunha, R.; Malva, J.O.; Ribeiro, J.A., FEBS Letters. 159 - 162. 2-3. 469. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034629239&partnerID=MN8TOARS . 10.1016/S0014-5793(00)01272-2 . FEBS Letters

Role of desensitization of AMPA receptors on the neuronal viability and an the [Ca2+](i) changes in cultured rat hippocampal neurons

Ambrósio, A.F.; Silva, A.P.; Malva, J.O.; Mesquita, J.F.; Carvalho, A.P.; Carvalho, C.M., European Journal of Neuroscience. 2021 - 2031. 6. 12. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034042462&partnerID=MN8TOARS . 10.1046/j.1460-9568.2000.00091.x . European Journal of Neuroscience

Carbamazepine inhibits L-type Ca2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists

Ambrósio, A.F.; Silva, A.P.; Malva, J.O.; Soares-Da-Silva, P.; Carvalho, A.P.; Carvalho, C.M., Neuropharmacology. 1349 - 1359. 9. 38. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-18244425608&partnerID=MN8TOARS . 10.1016/S0028-3908(99)00058-1 . Neuropharmacology

Kainate receptors coupled to G(i)/G(o) proteins in the rat hippocampus

Cunha, R.A.; Malva, J.O.; Ribeiro, J.A., Molecular Pharmacology. 429 - 433. 2. 56. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032793961&partnerID=MN8TOARS . Molecular Pharmacology

Kainate receptors in hippocampal CA3 subregion: evidence for a role in regulating neurotransmitter release

Malva, João O.; Carvalho, Arsélio P.; Carvalho, Caetana M., 1998. http://hdl.handle.net/10316/5471 .

Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: characterization of the activated voltage sensitive Ca2+ channels

Malva, João O.; Ambrósio, António F.; Carvalho, Arsélio P.; Carvalho, Caetana M., 1998. http://hdl.handle.net/10316/5472 .

Commentary: Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: Characterization of the activated voltage sensitive Ca2+ channels

Malva, J.O.; Ambrsio, A.F.; Carvalho, A.P.; Carvalho, C.M., Neurochemistry International. 7 - 16. 1. 32. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031594364&partnerID=MN8TOARS . 10.1016/S0197-0186(97)00048-X . Neurochemistry International

Commentary: Kainate receptors in hippocampal CA3 subregion: Evidence for a role in regulating neurotransmitter release

Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., Neurochemistry International. 1 - 6. 1. 32. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031606083&partnerID=MN8TOARS . 10.1016/S0197-0186(97)00046-6 . Neurochemistry International

Modulation of glutamate release from rat hippocampal synaptosomes by nitric oxide

Sequeira, S.M.; Ambrósio, A.F.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., Nitric Oxide - Biology and Chemistry. 315 - 329. 4. 1. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345451156&partnerID=MN8TOARS . 10.1006/niox.1997.0144 . Nitric Oxide - Biology and Chemistry

Inhibition of N-, P/Q- and other types of Ca2+ channels in rat hippocampal nerve terminals by the adenosine A1 receptor

Ambrósio, A.F.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., European Journal of Pharmacology. 301 - 310. 2-3. 340. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344813710&partnerID=MN8TOARS . 10.1016/S0014-2999(97)01451-9 . European Journal of Pharmacology

Modulation of Ca2+ channels by activation of adenosine A1 receptors in rat striatal glutamatergic nerve terminals

Ambrósio, A.F.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., Neuroscience Letters. 163 - 166. 3. 220. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030595814&partnerID=MN8TOARS . 10.1016/S0304-3940(96)13252-3 . Neuroscience Letters

Modulation oh intracellular ca2+ and exocytotic glulamate release by adhnosinh a1 rhchptor activation in the hippocampus

Carvalho, C.; Ambrócio, A.; Malva, J.; Carvlho, A., FASEB Journal. 3. 10. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-25744431605&partnerID=MN8TOARS . FASEB Journal

Identification of a presynaptic kainate receptor which modules the exocytotic release of glutamate in rat hippocampal CA3 synaptosomes

Malva, J.; Carvalho, A.; Çarvalho, C., FASEB Journal. 3. 10. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748975701&partnerID=MN8TOARS . FASEB Journal

Domoic acid induces the release of glutamate in the rat hippocampal CA3 sub-region

Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., NeuroReport. 1330 - 1334. 7. 7. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029679826&partnerID=MN8TOARS . NeuroReport

Characterization of voltage-sensitive Ca2+ channels activated by presynaptic glutamate receptor stimulation in hippocampus

Carvalho, C.M.; Malva, J.O.; Duarte, C.B.; Carvalho, A.P., Annals of the New York Academy of Sciences. 457 - 459. 757. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029129986&partnerID=MN8TOARS . 10.1111/j.1749-6632.1995.tb17505.x . Annals of the New York Academy of Sciences

Relation of [Ca2+]i to dopamine release in striatal synaptosomes: role of Ca2+ channels

Carvalho, C.M.; Ferreira, I.L.; Duarte, C.B.; Malva, J.O.; Tretter, L.; Adam-Vizi, V.; Carvalho, A.P., Brain Research. 234 - 244. 2. 669. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028839020&partnerID=MN8TOARS . Brain Research

A functionally active presynaptic high-affinity kainate receptor in the rat hippocampal CA3 subregion

Malva, J.O.; Ambrósio, A.F.; Cunha, R.A.; Ribeiro, J.A.; Carvalho, A.P.; Carvalho, C.M., Neuroscience Letters. 83 - 86. 2. 185. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028912732&partnerID=MN8TOARS . Neuroscience Letters

Modulation of dopamine and noradrenaline release and of intracellular Ca2+ concentration by presynaptic glutamate receptors in hippocampus

Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., British Journal of Pharmacology. 1439 - 1447. 4. 113. 1994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027968075&partnerID=MN8TOARS . British Journal of Pharmacology

Action of antiestrogens on the (Ca2+ + Mg2+)-ATPase and Na+/Ca2+ exchange of brain cortex membranes

Malva, J.O.; Lopes, M.C.F.; Vale, M.G.P.; Carvalho, A.P., Biochemical Pharmacology. 1877 - 1884. 8. 40. 1990. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025196039&partnerID=MN8TOARS . Biochemical Pharmacology