Physiological Ageing
Inflammation and Stem Cell Dynamics
Age-related Chronic Diseases
Active Ageing
Healthy Living
Health Management
Impact of inflammation and stem cell dynamics in physiological ageing
Common mechanisms related with inflammation and stem cell dynamics in age-related chronic diseases
Good practices and technologies supporting healthy living and active ageing
Empowerment of citizens towards the adoption of adequate health management skills and healthy lifestyles
The research group has been inspired by the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) and by Ageing@Coimbra Consortium (EIP on AHA Reference Site) to deliver innovative knowledge transfer on ageing research and good practices to support healthy living and better health care. The key objectives of the research group are addressed the three inspiring questions:
Why do we age?
How do we age?
How do we support healthy living and active ageing?
The mainstream topics enclose fundamental and translational research related with the most prevalent age-related chronic conditions, including: neurodegenerative diseases; musculoskeletal diseases; respiratory diseases, immunology, cardiovascular diseases, diabetes, cancer, adherence to therapy and polymedication, falls and frailty, integrated care and palliative care.
The research team is highly interdisciplinary and encloses fundamental and applied research, medical, nursing and pharmaceutical care, ehealth, health literacy and citizens empowering skills. The members of the team have been founders and coordinators of Ageing@Coimbra; members of EIT Health Knowledge Innovation Community (KIC); coordinators of RESOE (North-West Iberian regional cluster) task force on Demographic Changes and Ageing; members of coordination board of the Reference Site Collaborative Network; coordinators of relevant scientific societies (eg. Neuroscience, Internal Medicine (including Geriatrics), Rheumatology, Forensic Medicine, Atherosclerosis, among others).
Information about journal articles, updated at 03-11-2024, from platform CIÊNCIAVITAE.
ApoE Mimetic Peptides to Improve the Vicious Cycle of Malnutrition and Enteric Infections by Targeting the Intestinal and Blood-Brain Barriers
Reinaldo B. Oriá; Raul S. Freitas; Cássia R. Roque; José Carlos R. Nascimento; Ana Paula Silva; João O. Malva; Richard L. Guerrant; Michael P. Vitek, 2023. Pharmaceutics. 2023. https://doi.org/10.3390/pharmaceutics15041086 . 10.3390/pharmaceutics15041086 . Pharmaceutics
Chronic Methylmercury Intoxication Induces Systemic Inflammation, Behavioral, and Hippocampal Amino Acid Changes in C57BL6J Adult Mice
Tyciane S. Nascimento; Daniel V. Pinto; Ronaldo pereira dias; Ramon S. Raposo; Paulo Iury Gomes Nunes; Cássia R. Roque; Flavia Santos; et al, 2022. International Journal of Molecular Sciences. 2022. https://www.mdpi.com/1422-0067/23/22/13837 . 10.3390/ijms232213837 . International Journal of Molecular Sciences
Cellular and Molecular Mechanisms Mediating Methylmercury Neurotoxicity and Neuroinflammation
Novo, João P.; Martins, Beatriz; Raposo, Ramon S.; Pereira, Frederico C.; Oriá, Reinaldo B.; Malva, João O.; Fontes-Ribeiro, Carlos, 2021. International Journal of Molecular Sciences. 6. 22. 2021. http://dx.doi.org/10.3390/ijms22063101 . 10.3390/ijms22063101 . International Journal of Molecular Sciences
The Transition From Undernutrition to Overnutrition Under Adverse Environments and Poverty: The Risk for Chronic Diseases
Leocádio, Paola Caroline L.; Lopes, Synara C.; Dias, Ronaldo P.; Alvarez-Leite, Jacqueline I.; Guerrant, Richard L.; Malva, João O.; Oriá, Reinaldo B., 2021. Frontiers in Nutrition. 8. 2021. http://dx.doi.org/10.3389/fnut.2021.676044 . 10.3389/fnut.2021.676044 . Frontiers in Nutrition
Unhealthy lifestyles, environment, well-being and health capability in rural neighbourhoods: a community-based cross-sectional study
Azul, Anabela Marisa; Almendra, Ricardo; Quatorze, Marta; Loureiro, Adriana; Reis, Flávio; Tavares, Rui; Mota-Pinto, Anabela; et al, 2021. BMC Public Health. 1. 21. 2021. http://dx.doi.org/10.1186/s12889-021-11661-4 . 10.1186/s12889-021-11661-4 . BMC Public Health
Methylmercury Impact on Adult Neurogenesis: Is the Worst Yet to Come From Recent Brazilian Environmental Disasters?
Raposo RDS; Pinto DV; Moreira R; Dias RP; Fontes Ribeiro CA; Oriá RB; Malva JO, 2020. Frontiers in aging neuroscience. 2020. http://europepmc.org/abstract/med/33328968 . 10.3389/fnagi.2020.591601 . Frontiers in aging neuroscience
Correlation between work impairment, scores of rhinitis severity and asthma using the MASK-air® App.
Bédard A; Antó JM; Fonseca JA; Arnavielhe S; Bachert C; Bedbrook A; Bindslev-Jensen C; et al, 2020. Allergy. 2020. http://europepmc.org/abstract/med/31995656 . 10.1111/all.14204 . Allergy
Methylmercury Interactions With Gut Microbiota and Potential Modulation of Neurogenic Niches in the Brain.
Pinto DV; Raposo RS; Matos GA; Alvarez-Leite JI; Malva JO; Oriá RB, 2020. Frontiers in neuroscience. 2020. http://europepmc.org/abstract/med/33224022 . 10.3389/fnins.2020.576543 . Frontiers in neuroscience
Editorial: Interplay Between Nutrition, the Intestinal Microbiota and the Immune System.
Oriá RB; Empadinhas N; Malva JO, 2020. Frontiers in immunology. 2020. http://europepmc.org/abstract/med/32849628 . 10.3389/fimmu.2020.01758 . Frontiers in immunology
Advancing tools to promote health equity across European Union regions: the EURO-HEALTHY project.
Santana P; Freitas Â; Stefanik I; Costa C; Oliveira M; Rodrigues TC; Vieira A; et al, 2020. Health research policy and systems. 2020. http://europepmc.org/abstract/med/32054540 . 10.1186/s12961-020-0526-y . Health research policy and systems
Calcium Signaling in Aging and Neurodegenerative Diseases 2019.
Cortes L; Malva J; Rego AC; Pereira CF, 2020. International journal of molecular sciences. 2020. http://europepmc.org/abstract/med/32046230 . 10.3390/ijms21031125 . International journal of molecular sciences
ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice.
Bousquet J; Anto JM; Bachert C; Haahtela T; Zuberbier T; Czarlewski W; Bedbrook A; et al, 2020. Allergy. 2020. http://europepmc.org/abstract/med/32512619 . 10.1111/all.14422 . Allergy
Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 1)
Bousquet, Jean; Pham-Thi, Nhân; Bedbrook, Anna; Agache, Ioana; Annesi-Maesano, Isabella; Ansotegui, Ignacio; Anto, Josep M; et al, 2019. 2019. http://hdl.handle.net/10400.6/9366 . 10.21037/jtd.2019.08.64 .
Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases
Bousquet, J Jean; Schünemann, Holger J; Togias, Alkis; Erhola, Marina; Hellings, Peter W; Zuberbier, Torsten; Agache, Ioana; et al, 2019. 2019. http://hdl.handle.net/10400.6/9365 . 10.1186/s13601-019-0279-2 .
Development of a Healthy Lifestyle Assessment Toolkit for the General Public.
Reis F; Sá-Moura B; Guardado D; Couceiro P; Catarino L; Mota-Pinto A; Veríssimo MT; et al, 2019. Frontiers in medicine. 2019. http://europepmc.org/abstract/med/31316985 . 10.3389/fmed.2019.00134 . Frontiers in medicine
Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study.
Bédard A; Basagaña X; Anto JM; Garcia-Aymerich J; Devillier P; Arnavielhe S; Bedbrook A; et al, 2019. The Journal of allergy and clinical immunology. 2019. http://europepmc.org/abstract/med/30951790 . 10.1016/j.jaci.2019.01.053 . The Journal of allergy and clinical immunology
Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma.
Bousquet J; Bedbrook A; Czarlewski W; Onorato GL; Arnavielhe S; Laune D; Mathieu-Dupas E; et al, 2019. Clinical and translational allergy. 2019. http://europepmc.org/abstract/med/30911372 . 10.1186/s13601-019-0252-0 . Clinical and translational allergy
Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study.
Menditto E; Costa E; Midão L; Bosnic-Anticevich S; Novellino E; Bialek S; Briedis V; et al, 2019. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2019. http://europepmc.org/abstract/med/30597673 . 10.1111/cea.13333 . Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Adult Hippocampal Neurogenesis in Different Taxonomic Groups: Possible Functional Similarities and Striking Controversies.
Augusto-Oliveira M; Arrifano GPF; Malva JO; Crespo-Lopez ME, 2019. Cells. 2019. http://europepmc.org/abstract/med/30764477 . 10.3390/cells8020125 . Cells
The Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing.
Bousquet J; Illario M; Farrell J; Batey N; Carriazo AM; Malva J; Hajjam J; et al, 2019. Translational medicine @ UniSa. 2019. http://europepmc.org/abstract/med/31360670 . Translational medicine @ UniSa
ARIA pharmacy 2018: Allergic rhinitis care pathways for community pharmacy
Bosnic-Anticevich, Sinthia; Costa, Elisio; Menditto, Enrica; Lourenço, Olga; Novellino, Ettore; Bialek, Slawomir; Briedis, Vitalis; et al, 2019. 2019. http://hdl.handle.net/10400.6/9359 . 10.1111/all.13701 .
What Do Microglia Really Do in Healthy Adult Brain?
Marcus Oliveira; Gabriela Arrifano; Amanda Lopes-Araújo; Leticia Santos-Sacramento; Priscila Y. Takeda; Anthony DC; João O. Malva; Maria Elena Crespo-Lopez, 2019. Cells. 2019. https://www.mdpi.com/2073-4409/8/10/1293 . 10.3390/cells8101293 . Cells
Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology.
Bousquet J; Hellings PW; Agache I; Amat F; Annesi-Maesano I; Ansotegui IJ; Anto JM; et al, 2018. The Journal of allergy and clinical immunology. 2018. http://europepmc.org/abstract/med/30273709 . 10.1016/j.jaci.2018.08.049 . The Journal of allergy and clinical immunology
Transfer of innovation on allergic rhinitis and asthma multimorbidity in the elderly (MACVIA-ARIA) - EIP on AHA Twinning Reference Site (GARD research demonstration project).
Bousquet J; Agache I; Aliberti MR; Angles R; Annesi-Maesano I; Anto JM; Arnavielhe S; et al, 2018. Allergy. 2018. http://europepmc.org/abstract/med/28600902 . 10.1111/all.13218 . Allergy
MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence.
Bousquet J; Arnavielhe S; Bedbrook A; Bewick M; Laune D; Mathieu-Dupas E; Murray R; et al, 2018. Clinical and translational allergy. 2018. http://europepmc.org/abstract/med/30386555 . 10.1186/s13601-018-0227-6 . Clinical and translational allergy
Effect of Hypoproteic and High-Fat Diets on Hippocampal Blood-Brain Barrier Permeability and Oxidative Stress.
de Aquino CC; Leitão RA; Oliveira Alves LA; Coelho-Santos V; Guerrant RL; Ribeiro CF; Malva JO; Silva AP; Oriá RB, 2018. Frontiers in nutrition. 2018. http://europepmc.org/abstract/med/30687711 . 10.3389/fnut.2018.00131 . Frontiers in nutrition
A case study of polypharmacy management in nine European countries: Implications for change management and implementation.
McIntosh J; Alonso A; MacLure K; Stewart D; Kempen T; Mair A; Castel-Branco M; et al, 2018. PloS one. 2018. http://europepmc.org/abstract/med/29668763 . 10.1371/journal.pone.0195232 . PloS one
The Quadruple Helix-Based Innovation Model of Reference Sites for Active and Healthy Ageing in Europe: The Ageing@Coimbra Case Study.
Malva JO; Amado A; Rodrigues A; Mota-Pinto A; Cardoso AF; Teixeira AM; Todo-Bom A; et al, 2018. Frontiers in medicine. 2018. http://europepmc.org/abstract/med/29868588 . 10.3389/fmed.2018.00132 . Frontiers in medicine
Geolocation with respect to personal privacy for the Allergy Diary app - a MASK study.
Samreth D; Arnavielhe S; Ingenrieth F; Bedbrook A; Onorato GL; Murray R; Almeida R; et al, 2018. The World Allergy Organization Journal. 2018. http://europepmc.org/abstract/med/30061979 . 10.1186/s40413-018-0194-3 . The World Allergy Organization Journal
Revisiting Inbred Mouse Models to Study the Developing Brain: The Potential Role of Intestinal Microbiota.
Oriá RB; Malva JO; Foley PL; Freitas RS; Bolick DT; Guerrant RL, 2018. Frontiers in Human Neuroscience. 2018. http://europepmc.org/abstract/med/30283311 . 10.3389/fnhum.2018.00358 . Frontiers in Human Neuroscience
CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis: a SUNFRAIL report.
Bousquet J; Onorato GL; Bachert C; Barbolini M; Bedbrook A; Bjermer L; de Sousa JC; et al, 2017. Clinical and translational allergy. 2017. http://europepmc.org/abstract/med/29075437 . 10.1186/s13601-017-0173-8 . Clinical and translational allergy
Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).
Bousquet J; Farrell J; Crooks G; Hellings P; Bel EH; Bewick M; Chavannes NH; et al, 2017. 2017. http://europepmc.org/abstract/med/28239450 . 10.1186/s13601-016-0135-6 .
Silencing of P2X7R by RNA interference in the hippocampus can attenuate morphological and behavioral impact of pilocarpine-induced epilepsy.
Amorim RP; Araújo MGL; Valero J; Lopes-Cendes I; Pascoal VDB; Malva JO; da Silva Fernandes MJ, 2017. Purinergic Signalling. 2017. http://europepmc.org/abstract/med/28707031 . 10.1007/s11302-017-9573-4 . Purinergic Signalling
Building Bridges for Innovation in Ageing: Synergies between Action Groups of the EIP on AHA.
Bousquet J; Bewick M; Cano A; Eklund P; Fico G; Goswami N; Guldemond NA; et al, 2017. 2017. http://europepmc.org/abstract/med/27999855 . 10.1007/s12603-016-0803-1 .
Impact of Neuroinflammation on Hippocampal Neurogenesis: Relevance to Aging and Alzheimer's Disease.
Valero J; Bernardino L; Cardoso FL; Silva AP; Fontes-Ribeiro C; Ambrósio AF; Malva JO, 2017. Journal of Alzheimer's disease : JAD. 2017. http://europepmc.org/abstract/med/28671124 . 10.3233/jad-170239 . Journal of Alzheimer's disease : JAD
A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people.
Stewart D; Gibson-Smith K; MacLure K; Mair A; Alonso A; Codina C; Cittadini A; et al, 2017. PloS one. 2017. http://europepmc.org/abstract/med/29155870 . 10.1371/journal.pone.0188348 . PloS one
Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis - A EUFOREA-ARIA-EPOS-AIRWAYS ICP statement.
Hellings PW; Fokkens WJ; Bachert C; Akdis CA; Bieber T; Agache I; Bernal-Sprekelsen M; et al, 2017. Allergy. 2017. http://europepmc.org/abstract/med/28306159 . 10.1111/all.13162 . Allergy
Validation of the MASK-rhinitis visual analogue scale on smartphone screens to assess allergic rhinitis control.
Caimmi D; Baiz N; Tanno LK; Demoly P; Arnavielhe S; Murray R; Bedbrook A; et al, 2017. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2017. http://europepmc.org/abstract/med/28886234 . 10.1111/cea.13025 . Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Coxsackievirus Adenovirus Receptor Loss Impairs Adult Neurogenesis, Synapse Content, and Hippocampus Plasticity.
Zussy C; Loustalot F; Junyent F; Gardoni F; Bories C; Valero J; Desarménien MG; et al, 2016. 2016. http://europepmc.org/abstract/med/27629708 . 10.1523/jneurosci.0132-16.2016 .
Should we use gait speed in COPD, FEV1 in frailty and dyspnoea in both?
Bousquet J; Dinh-Xuan AT; Similowski T; Malva J; Ankri J; Barbagallo M; Fabbri L; et al, 2016. 2016. http://europepmc.org/abstract/med/27478189 . 10.1183/13993003.00633-2016 .
Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).
Bousquet J; Farrell J; Crooks G; Hellings P; Bel EH; Bewick M; Chavannes NH; et al, 2016. 2016. http://europepmc.org/abstract/med/27478588 . 10.1186/s13601-016-0116-9 .
ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle.
Bousquet J; Hellings PW; Agache I; Bedbrook A; Bachert C; Bergmann KC; Bewick M; et al, 2016. 2016. http://europepmc.org/abstract/med/28050247 . 10.1186/s13601-016-0137-4 .
Operational definition of active and healthy ageing: Roadmap from concept to change of management.
Malva JO; Bousquet J, 2016. 2016. http://europepmc.org/abstract/med/26704254 . 10.1016/j.maturitas.2015.11.004 .
Operational Definition of Active and Healthy Ageing (AHA): A Conceptual Framework.
Bousquet J; Kuh D; Bewick M; Standberg T; Farrell J; Pengelly R; Joel ME; et al, 2015. 2015. http://europepmc.org/abstract/med/26482699 . 10.1007/s12603-015-0589-6 .
Portugal at the cross road of international chronic respiratory programmes.
Bousquet J; Pinto JR; Barbara C; da Sousa JC; Fonseca J; Miguel JP; Boavida J; et al, 2015. 2015. http://europepmc.org/abstract/med/26275595 . 10.1016/j.rppnen.2015.07.001 .
Operational Definition of Active and Healthy Aging (AHA): The European Innovation Partnership (EIP) on AHA Reference Site Questionnaire: Montpellier October 20-21, 2014, Lisbon July 2, 2015.
Bousquet J; Malva J; Nogues M; Mañas LR; Vellas B; Farrell J; MACVIA Research Group, 2015. 2015. http://europepmc.org/abstract/med/26498697 . 10.1016/j.jamda.2015.09.004 .
New insights into the role of histamine in subventricular zone-olfactory bulb neurogenesis.
Eiriz MF; Valero J; Malva JO; Bernardino L, 2014. 2014. http://europepmc.org/abstract/med/24982610 . 10.3389/fnins.2014.00142 .
Long-term effects of an acute and systemic administration of LPS on adult neurogenesis and spatial memory.
Valero J; Mastrella G; Neiva I; Sánchez S; Malva JO, 2014. 2014. http://europepmc.org/abstract/med/24795557 . 10.3389/fnins.2014.00083 .
Modulation of subventricular zone oligodendrogenesis: a role for hemopressin?
Xapelli S; Agasse F; Grade S; Bernardino L; Ribeiro FF; Schitine CS; Heimann AS; et al, 2014. 2014. http://europepmc.org/abstract/med/24578683 . 10.3389/fncel.2014.00059 .
Can we talk about microglia without neurons? A discussion of microglial cell autonomous properties in culture.
Neiva I; Malva JO; Valero J, 2014. 2014. http://europepmc.org/abstract/med/25104923 . 10.3389/fncel.2014.00202 .
Growth hormone pathways signaling for cell proliferation and survival in hippocampal neural precursors from postnatal mice.
Devesa P; Agasse F; Xapelli S; Almengló C; Devesa J; Malva JO; Arce VM, 2014. 2014. http://europepmc.org/abstract/med/25156632 . 10.1186/1471-2202-15-100 .
Oligodendrogenesis from neural stem cells: Perspectives for remyelinating strategies.
Grade S; Bernardino L; Malva JO, 2013. 2013. http://europepmc.org/abstract/med/23340483 . 10.1016/j.ijdevneu.2013.01.004 .
Activation of Type 1 Cannabinoid Receptor (CB1R) promotes neurogenesis in murine subventricular zone cell cultures
Xapelli, Sara; Agasse, Fabienne; Sarda-Arroyo, Laura; Bernardino, Liliana; Santos, Tiago; Ribeiro, Filipa F.; Valero, Jorge; et al, 2013. 2013. http://hdl.handle.net/10400.1/11739 . 10.1371/journal.pone.0063529 .
Brain-derived neurotrophic factor promotes vasculature-associated migration of neuronal precursors toward the ischemic striatum.
Grade S; Weng YC; Snapyan M; Kriz J; Malva JO; Saghatelyan A, 2013. 2013. http://europepmc.org/abstract/med/23383048 . 10.1371/journal.pone.0055039 .
Galanin promotes neuronal differentiation in murine subventricular zone cell cultures.
Agasse F; Xapelli S; Coronas V; Christiansen SH; Rosa AI; Sardá-Arroyo L; Santos T; et al, 2013. 2013. http://europepmc.org/abstract/med/23327619 . 10.1089/scd.2012.0161 .
The effect of methamphetamine on subventricular zone neurogenesis: Cell death, proliferation and differentiation
Bento, A.R.; Baptista, S.; Malva, J.O.; Silva, A.P.; Agasse, F., 2012. 2012 IEEE 2nd Portuguese Meeting in Bioengineering, ENBENG 2012. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869407710&partnerID=MN8TOARS . 10.1109/ENBENG.2012.6331378 . 2012 IEEE 2nd Portuguese Meeting in Bioengineering, ENBENG 2012
Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures.
Baptista S; Bento AR; Gonçalves J; Bernardino L; Summavielle T; Lobo A; Fontes-Ribeiro C; et al, 2012. 2012. http://europepmc.org/abstract/med/22381583 . 10.1016/j.neuropharm.2012.02.015 .
Methamphetamine-induced changes in the mice hippocampal neuropeptide Y system: implications for memory impairment.
Gonçalves J; Baptista S; Olesen MV; Fontes-Ribeiro C; Malva JO; Woldbye DP; Silva AP, 2012. 2012. http://europepmc.org/abstract/med/23061411 . 10.1111/jnc.12052 .
Multifaces of neuropeptide Y in the brain - Neuroprotection, neurogenesis and neuroinflammation
Malva, J.O.; Xapelli, S.; Baptista, S.; Valero, J.; Agasse, F.; Ferreira, R.; Silva, A.P., 2012. Neuropeptides. 299 - 308. 6. 46. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869883047&partnerID=MN8TOARS . 10.1016/j.npep.2012.09.001 . Neuropeptides
Histamine stimulates neurogenesis in the rodent subventricular zone
Bernardino, Liliana; Eiriz, Maria Francisca; Santos, Tiago; Xapelli, Sara; Grade, Sofia; Rosa, Alexandra Isabel; Cortes, Luisa; et al, 2012. 2012. http://hdl.handle.net/10400.1/11105 . 10.1002/stem.1042 .
Neuropeptide Y inhibits interleukin-1 beta-induced microglia motility.
Ferreira R; Santos T; Cortes L; Cochaud S; Agasse F; Silva AP; Xapelli S; et al, 2012. 2012. http://europepmc.org/abstract/med/22007767 . 10.1111/j.1471-4159.2011.07541.x .
Polymeric nanoparticles to control the differentiation of neural stem cells in the subventricular zone of the brain.
Santos T; Ferreira R; Maia J; Agasse F; Xapelli S; Cortes L; Bragança J; et al, 2012. 2012. http://europepmc.org/abstract/med/23176155 . 10.1021/nn304541h .
Ampakine CX546 increases proliferation and neuronal differentiation in subventricular zone stem/progenitor cell cultures.
Schitine C; Xapelli S; Agasse F; Sardà-Arroyo L; Silva AP; De Melo Reis RA; de Mello FG; Malva JO, 2012. 2012. http://europepmc.org/abstract/med/22506985 . 10.1111/j.1460-9568.2012.08072.x .
Protective role of neuropeptide Y Y2 receptors in cell death and microglial response following methamphetamine injury.
Gonçalves J; Ribeiro CF; Malva JO; Silva AP, 2012. 2012. http://europepmc.org/abstract/med/22805317 . 10.1111/j.1460-9568.2012.08232.x .
Functional identification of neural stem cell-derived oligodendrocytes.
Grade S; Agasse F; Bernardino L; Malva JO; Silva CG; Cortes L; Eiriz, M.F.; et al, 2012. Current Stem Cell Research and Therapy. 288 - 296. 3. 6. 2012. http://europepmc.org/abstract/med/22610560 . 10.1007/978-1-61779-815-3_11 . Current Stem Cell Research and Therapy
Controlling the neuronal differentiation of stem cells by the intracellular delivery of retinoic acid-loaded nanoparticles.
Maia J; Santos T; Aday S; Agasse F; Cortes L; Malva JO; Bernardino L; Ferreira L, 2011. 2011. http://europepmc.org/abstract/med/21171566 . 10.1021/nn101724r .
Functional Identification of Cell Phenotypes Differentiating from Mice Retinal Neurospheres Using Single Cell Calcium Imaging
De Melo Reis, R.A.; Schitine, C.S.; Kofalvi, A.; Grade, S.; Cortes, L.; Gardino, P.F.; Malva, J.O.; de Mello, F.G., 2011. Cellular and Molecular Neurobiology. 1 - 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952606231&partnerID=MN8TOARS . 10.1007/s10571-011-9673-6 . Cellular and Molecular Neurobiology
NPY promotes chemokinesis and neurogenesis in the rat subventricular zone.
Thiriet N; Agasse F; Nicoleau C; Guégan C; Vallette F; Cadet JL; Jaber M; Malva JO; Coronas V, 2011. 2011. http://europepmc.org/abstract/med/21175616 . 10.1111/j.1471-4159.2010.07154.x .
Methamphetamine exerts toxic effects on subventricular zone stem/progenitor cells and inhibits neuronal differentiation.
Bento AR; Baptista S; Malva JO; Silva AP; Agasse F, 2011. 2011. http://europepmc.org/abstract/med/21453012 . 10.1089/rej.2010.1109 .
Functional identification of cell phenotypes differentiating from mice retinal neurospheres using single cell calcium imaging.
De Melo Reis, R.A.; Schitine, C.S.; Köfalvi, A.; Grade, S.; Cortes, L.; Gardino, P.F.; Malva, J.O.; de Mello, F.G., 2011. Cellular and molecular neurobiology. 835 - 846. 6. 31. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856384867&partnerID=MN8TOARS . Cellular and molecular neurobiology
Neuropeptide Y modulation of interleukin-1{beta} (IL-1{beta})-induced nitric oxide production in microglia.
Ferreira R; Xapelli S; Santos T; Silva AP; Cristóvão A; Cortes L; Malva JO, 2010. 2010. http://europepmc.org/abstract/med/20959451 . 10.1074/jbc.M110.164020 .
The angiogenic factor angiopoietin-1 is a proneurogenic peptide on subventricular zone stem/progenitor cells.
Rosa AI; Gonçalves J; Cortes L; Bernardino L; Malva JO; Agasse F, 2010. 2010. http://europepmc.org/abstract/med/20357108 . 10.1523/JNEUROSCI.5597-09.2010 .
Brain Injury Associated With Widely Abused Amphetamines: Neuroinflammation, Neurogenesis And Blood-Brain Barrier
Silva, A.P.; Martins, T.; Baptista, S.; Gonçalves, J.; Agasse, F.; Malva, J.O., 2010. Current Drug Abuse Reviews. 239 - 254. 4. 3. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-79551645771&partnerID=MN8TOARS . Current Drug Abuse Reviews
Biapigenin modulates the activity of the adenine nucleotide translocator in isolated rat brain mitochondria.
Silva BA; Oliveira PJ; Cristóvão A; Dias AC; Malva JO, 2010. 2010. http://europepmc.org/abstract/med/19597902 . 10.1007/s12640-009-9082-5 .
Brain injury associated with widely abused amphetamines: neuroinflammation, neurogenesis and blood-brain barrier.
Silva AP; Martins T; Baptista S; Gonçalves J; Agasse F; Malva JO, 2010. 2010. http://europepmc.org/abstract/med/21208167 .
Methamphetamine-induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin
Faculdade de Ciências, 2010. 2010. https://repositorio-aberto.up.pt/handle/10216/91224 . 10.1111/j.1460-9568.2009.07059.x .
Transthyretin knockout mice display decreased susceptibility to AMPA-induced neurodegeneration.
Nunes AF; Montero M; Franquinho F; Santos SD; Malva J; Zimmer J; Sousa MM, 2009. 2009. http://europepmc.org/abstract/med/19595729 . 10.1016/j.neuint.2009.07.001 .
Effects of Starch/ Polycaprolactone-based Blends for Spinal Cord Injury Regeneration in Neurons/Glial Cells Viability and Proliferation
Salgado, A.J.; Sousa, R.A.; Fraga, J.S.; Pego, J.M.; Silva, B.A.; Malva, J.O.; Neves, N.M.; Reis, R.L.; Sousa, N., 2009. Journal of Bioactive and Compatible Polymers. 235 - 248. 3. 24. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-65649101219&partnerID=MN8TOARS . 10.1177/0883911509104081 . Journal of Bioactive and Compatible Polymers
St. John's Wort (Hypericum perforatum) extracts and isolated phenolic compounds are effective antioxidants in several in vitro models of oxidative stress
Silva, B.A.; Malva, J.O.; Dias, A.C.P., 2008. Food Chemistry. 611 - 619. 3. 110. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-42649099265&partnerID=MN8TOARS . 10.1016/j.foodchem.2008.02.047 . Food Chemistry
Quercetin, kaempferol and biapigenin from hypericum perforatum are neuroprotective against excitotoxic insults
Silva, B.; Oliveira, P.J.; Dias, A.; Malva, J.O., 2008. Neurotoxicity Research. 265 - 279. 3-4. 13. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-55249095521&partnerID=MN8TOARS . 10.1007/BF03033510 . Neurotoxicity Research
Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: A role for microglia
Xapelli, S.; Bernardino, L.; Ferreira, R.; Grade, S.; Silva, A.P.; Salgado, J.R.; Cavadas, C.; et al, 2008. European Journal of Neuroscience. 2089 - 2102. 8. 27. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-42049112780&partnerID=MN8TOARS . 10.1111/j.1460-9568.2008.06172.x . European Journal of Neuroscience
Tumor necrosis factor-alpha modulates survival, proliferation, and neuronal differentiation in neonatal subventricular zone cell cultures.
Bernardino L; Agasse F; Silva B; Ferreira R; Grade S; Malva JO; Bernardino, Liliana; et al, 2008. 2008. http://europepmc.org/abstract/med/18583543 . 10.1634/stemcells.2007-0914 .
Neuropeptide Y promotes neurogenesis in murine subventricular zone.
Agasse F; Bernardino L; Kristiansen H; Christiansen SH; Ferreira R; Silva B; Grade S; Woldbye DP; Malva JO, 2008. 2008. http://europepmc.org/abstract/med/18388302 . 10.1634/stemcells.2008-0056 .
Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X7 receptor-mediated IL-1beta release.
Bernardino L; Balosso S; Ravizza T; Marchi N; Ku G; Randle JC; Malva JO; et al, 2008. 2008. http://europepmc.org/abstract/med/18384650 . 10.1111/j.1471-4159.2008.05387.x .
Methamphetamine-induced early increase of IL-6 and TNF-alpha mRNA expression in the mouse brain.
Gonçalves J; Martins T; Ferreira R; Milhazes N; Borges F; Ribeiro CF; Malva JO; Macedo TR; Silva AP, 2008. 2008. http://europepmc.org/abstract/med/18991854 . 10.1196/annals.1432.043 .
Response to histamine allows the functional identification of neuronal progenitors, neurons, astrocytes, and immature cells in subventricular zone cell cultures.
Agasse F; Bernardino L; Silva B; Ferreira R; Grade S; Malva JO, 2008. 2008. http://europepmc.org/abstract/med/18279032 . 10.1089/rej.2007.0600 .
GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses.
Pinheiro PS; Perrais D; Coussen F; Barhanin J; Bettler B; Mann JR; Malva JO; Heinemann SF; Mulle C, 2007. 2007. http://europepmc.org/abstract/med/17620617 . 10.1073/pnas.0608891104 .
Susceptibility of hippocampal neurons to Aß peptide toxicity is associated with perturbation of Ca2+ homeostasis
Resende, R.; Pereira, C.; Agostinho, P.; Vieira, A.P.; Malva, J.O.; Oliveira, C.R., 2007. Brain Research. 11 - 21. 1. 1143. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947303240&partnerID=MN8TOARS . 10.1016/j.brainres.2007.01.071 . Brain Research
Neuropeptide Y can rescue neurons from cell death following the application of an excitotoxic insult with kainate in rat organotypic hippocampal slice cultures
Xapelli, S.; Silva, A.P.; Ferreira, R.; Malva, J.O., 2007. Peptides. 288 - 294. 2. 28. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846629106&partnerID=MN8TOARS . 10.1016/j.peptides.2006.09.031 . Peptides
Mitochondria as targets for neuronal protection against excitotoxicity: A role for phenolic compounds?
Silva, B.A.; Oliveira, P.J.; Dias, A.C.P.; Malva, J.O., 2007. Central Nervous System Agents in Medicinal Chemistry. 205 - 222. 3. 7. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548408654&partnerID=MN8TOARS . 10.2174/187152407781669152 . Central Nervous System Agents in Medicinal Chemistry
Protein kinase C activity blocks neuropeptide Y-mediated inhibition of glutamate release and contributes to excitability of the hippocampus in status epilepticus.
Silva AP; Lourenço J; Xapelli S; Ferreira R; Kristiansen H; Woldbye DP; Oliveira CR; Malva JO, 2007. 2007. http://europepmc.org/abstract/med/17167071 . 10.1096/fj.06-6163com .
Neuropeptide Y as an endogenous antiepileptic, neuroprotective and pro-neurogenic peptide.
Xapelli S; Agasse F; Ferreira R; Silva AP; Malva JO, 2006. 2006. http://europepmc.org/abstract/med/18221213 . 10.2174/157488906778773689 .
Inactivation of caspase-1 in rodent brain: A novel anticonvulsive strategy
Ravizza, T.; Lucas, S.-M.; Balosso, S.; Bernardino, L.; Ku, G.; Noé, F.; Malva, J.; et al, 2006. Epilepsia. 1160 - 1168. 7. 47. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746145901&partnerID=MN8TOARS . 10.1111/j.1528-1167.2006.00590.x . Epilepsia
Phytochemical and antioxidant characterization of Hypericum perforatum alcoholic extracts
Silva, B.A.; Ferreres, F.; Malva, J.O.; Dias, A.C.P., 2005. Food Chemistry. 157 - 167. 1-2. 90. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-4644274688&partnerID=MN8TOARS . 10.1016/j.foodchem.2004.03.049 . Food Chemistry
Proteolysis of NR2B by calpain in the hippocampus of epileptic rats.
Araújo IM; Xapelli S; Gil JM; Mohapel P; Petersén A; Pinheiro PS; Malva JO; et al, 2005. 2005. http://europepmc.org/abstract/med/15729144 . 10.1097/00001756-200503150-00017 .
Presynaptic kainate receptors are localized close to release sites in rat hippocampal synapses
Pinheiro, P.S.; Rodrigues, R.J.; Rebola, N.; Xapelli, S.; Oliveira, C.R.; Malva, J.O., 2005. Neurochemistry International. 309 - 316. 5. 47. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-22044433723&partnerID=MN8TOARS . 10.1016/j.neuint.2005.05.007 . Neurochemistry International
Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats.
Silva AP; Xapelli S; Pinheiro PS; Ferreira R; Lourenço J; Cristóvão A; Grouzmann E; et al, 2005. 2005. http://europepmc.org/abstract/med/15773916 . 10.1111/j.1471-4159.2004.03005.x .
Inflammation and neurogenesis in temporal lobe epilepsy
Bernardino, L.; Ferreira, R.; Cristóvão, A.J.; Sales, F.; Malva, J.O., 2005. Current Drug Targets: CNS and Neurological Disorders. 349 - 360. 4. 4. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23144431758&partnerID=MN8TOARS . 10.2174/1568007054546171 . Current Drug Targets: CNS and Neurological Disorders
Editorial
Malva, J.O., 2005. Current Drug Targets: CNS and Neurological Disorders. 4. 4. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23144460680&partnerID=MN8TOARS . 10.2174/1568007054546135 . Current Drug Targets: CNS and Neurological Disorders
Presynaptic kainate receptors modulating glutamatergic transmission in the rat hippocampus are inhibited by arachidonic acid.
Cunha RA; Ribeiro JA; Malva JO, 2004. 2004. http://europepmc.org/abstract/med/14643755 . 10.1016/S0197-0186(03)00167-0 .
Neuroprotective effect of H. perforatum extracts on beta-amyloid-induced neurotoxicity.
Silva BA; Dias AC; Ferreres F; Malva JO; Oliveira CR, 2004. 2004. http://europepmc.org/abstract/med/15325964 . 10.1007/BF03033214 .
Neuroprotective properties of Valeriana officinalis extracts.
Malva JO; Santos S; Macedo T, 2004. 2004. http://europepmc.org/abstract/med/15325965 . 10.1007/BF03033215 .
Neurotoxicity induced by antiepileptic drugs in cultured hippocampal neurons: a comparative study between carbamazepine, oxcarbazepine, and two new putative antiepileptic drugs, BIA 2-024 and BIA 2-093.
Araújo IM; Ambrósio AF; Leal EC; Verdasca MJ; Malva JO; Soares-da-Silva P; Carvalho AP; Carvalho CM, 2004. 2004. http://europepmc.org/abstract/med/15571507 . 10.1111/j.0013-9580.2004.14104.x .
Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures.
Rego AC; Monteiro NM; Silva AP; Gil J; Malva JO; Oliveira CR, 2003. 2003. http://europepmc.org/abstract/med/12887678 . 10.1046/j.1471-4159.2003.01898.x .
Functional interaction between neuropeptide Y receptors and modulation of calcium channels in the rat hippocampus.
Silva AP; Carvalho AP; Carvalho CM; Malva JO, 2003. 2003. http://europepmc.org/abstract/med/12623227 . 10.1016/S0028-3908(02)00382-9 .
Subcellular localization of adenosine A(1) receptors in nerve terminals and synapses of the rat hippocampus.
Rebola N; Pinheiro PC; Oliveira CR; Malva JO; Cunha RA, 2003. 2003. http://europepmc.org/abstract/med/14499945 . 10.1016/S0006-8993(03)03247-5 .
Solubilization and immunological identification of presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in the rat hippocampus.
Pinheiro PS; Rodrigues RJ; Silva AP; Cunha RA; Oliveira CR; Malva JO, 2003. 2003. http://europepmc.org/abstract/med/12499049 . 10.1016/S0304-3940(02)01217-X .
Activation of neuropeptide Y receptors is neuroprotective against excitotoxicity in organotypic hippocampal slice cultures
Silva, Ana P.; Pinheiro, Paulo S.; Carvalho, Arsélio P.; Carvalho, Caetana M.; Jakobsen, Birthe; Zimmer, Jens; Malva, João O.; et al, 2003. 2003. http://hdl.handle.net/10316/12831 . 10.1523/JNEUROSCI.1510-05.2005 .
Understanding the physiology of glutamate receptors by use of a protocol for neuronal staining
Malva, J.O.; Vieira, A.P.; Oliveira, C.R.; Malva JO; Vieira AP; Oliveira CR, 2003. American Journal of Physiology - Advances in Physiology Education. 78 - 85. 1-4. 27. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346502965&partnerID=MN8TOARS . American Journal of Physiology - Advances in Physiology Education
Cobalt staining of hippocampal neurons mediated by non-desensitizing activation of AMPA but not kainate receptors.
Malva JO; Vieira AP; Ambrósio AF; Oliveira CR, 2003. 2003. http://europepmc.org/abstract/med/12858045 . 10.1097/00001756-200305060-00014 .
Presynaptic modulation controlling neuronal excitability and epileptogenesis: role of kainate, adenosine and neuropeptide Y receptors.
Malva JO; Silva AP; Cunha RA, 2003. 2003. http://europepmc.org/abstract/med/14570395 . 10.1023/A:1025618324593 .
Presynaptic N-methyl-D-aspartate receptor activation inhibits neurotransmitter release through nitric oxide formation in rat hippocampal nerve terminals
Sequeira, S.M.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., 2001. Molecular Brain Research. 111 - 118. 1-2. 89. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035906241&partnerID=MN8TOARS . 10.1016/S0169-328X(01)00069-9 . Molecular Brain Research
Inhibition of glutamate release by BIA 2-093 and BIA 2-024, two novel derivatives of carbamazepine, due to blockade of sodium but not calcium channels
Ambrósio, A.F.; Silva, A.P.; Malva, J.O.; Soares-da-Silva, P.; Carvalho, A.P.; Carvalho, C.M., 2001. Biochemical Pharmacology. 1271 - 1275. 10. 61. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035873841&partnerID=MN8TOARS . 10.1016/S0006-2952(01)00584-6 . Biochemical Pharmacology
Role of kainate receptor activation and desensitization on the [Ca2+]i changes in cultured rat hippocampal neurons
Silva, A.P.; Malva, J.O.; Ambrósio, A.F.; Salgado, A.J.; Carvalho, A.P.; Carvalho, C.M., 2001. Journal of Neuroscience Research. 378 - 386. 5. 65. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035448626&partnerID=MN8TOARS . 10.1002/jnr.1164 . Journal of Neuroscience Research
Modulation of intracellular calcium changes and glutamate release by neuropeptide Y1 and Y2 receptors in the rat hippocampus: Differential effects in CA1, CA3 and dentate gyrus
Silva, A.P.; Carvalho, A.P.; Carvalho, C.M.; Malva, J.O., 2001. Journal of Neurochemistry. 286 - 296. 2. 79. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034770180&partnerID=MN8TOARS . 10.1046/j.1471-4159.2001.00560.x . Journal of Neurochemistry
Neurotoxic/neuroprotective profile of carbamazepine, oxcarbazepine and two new putative antiepileptic drugs, BIA 2-093 and BIA 2-024
Ambrósio, A.F.; Silva, A.P.; Araújo, I.; Malva, J.O.; Soares-da-Silva, P.; Carvalho, A.P.; Carvalho, C.M., 2000. European Journal of Pharmacology. 191 - 201. 2. 406. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034644868&partnerID=MN8TOARS . 10.1016/S0014-2999(00)00659-2 . European Journal of Pharmacology
Role of desensitization of AMPA receptors on the neuronal viability and an the [Ca2+](i) changes in cultured rat hippocampal neurons
Ambrósio, A.F.; Silva, A.P.; Malva, J.O.; Mesquita, J.F.; Carvalho, A.P.; Carvalho, C.M., 2000. European Journal of Neuroscience. 2021 - 2031. 6. 12. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034042462&partnerID=MN8TOARS . 10.1046/j.1460-9568.2000.00091.x . European Journal of Neuroscience
Pertussis toxin prevents presynaptic inhibition by kainate receptors of rat hippocampal [3H]GABA release
A. Cunha, R.; Malva, J.O.; Ribeiro, J.A., 2000. FEBS Letters. 159 - 162. 2-3. 469. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034629239&partnerID=MN8TOARS . 10.1016/S0014-5793(00)01272-2 . FEBS Letters
Carbamazepine inhibits L-type Ca2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists
Ambrósio, A.F.; Silva, A.P.; Malva, J.O.; Soares-Da-Silva, P.; Carvalho, A.P.; Carvalho, C.M., 1999. Neuropharmacology. 1349 - 1359. 9. 38. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-18244425608&partnerID=MN8TOARS . 10.1016/S0028-3908(99)00058-1 . Neuropharmacology
Kainate receptors coupled to G(i)/G(o) proteins in the rat hippocampus
Cunha, R.A.; Malva, J.O.; Ribeiro, J.A., 1999. Molecular Pharmacology. 429 - 433. 2. 56. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032793961&partnerID=MN8TOARS . Molecular Pharmacology
Commentary: Kainate receptors in hippocampal CA3 subregion: Evidence for a role in regulating neurotransmitter release
Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., 1998. Neurochemistry International. 1 - 6. 1. 32. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031606083&partnerID=MN8TOARS . 10.1016/S0197-0186(97)00046-6 . Neurochemistry International
Commentary: Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: Characterization of the activated voltage sensitive Ca2+ channels
Malva, J.O.; Ambrsio, A.F.; Carvalho, A.P.; Carvalho, C.M., 1998. Neurochemistry International. 7 - 16. 1. 32. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031594364&partnerID=MN8TOARS . 10.1016/S0197-0186(97)00048-X . Neurochemistry International
Kainate receptors in hippocampal CA3 subregion: evidence for a role in regulating neurotransmitter release
Malva, João O.; Carvalho, Arsélio P.; Carvalho, Caetana M., 1998. 1998. http://hdl.handle.net/10316/5471 .
Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: characterization of the activated voltage sensitive Ca2+ channels
Malva, João O.; Ambrósio, António F.; Carvalho, Arsélio P.; Carvalho, Caetana M., 1998. 1998. http://hdl.handle.net/10316/5472 .
Inhibition of N-, P/Q- and other types of Ca2+ channels in rat hippocampal nerve terminals by the adenosine A1 receptor
Ambrósio, A.F.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., 1997. European Journal of Pharmacology. 301 - 310. 2-3. 340. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344813710&partnerID=MN8TOARS . 10.1016/S0014-2999(97)01451-9 . European Journal of Pharmacology
Modulation of glutamate release from rat hippocampal synaptosomes by nitric oxide
Sequeira, S.M.; Ambrósio, A.F.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., 1997. Nitric Oxide - Biology and Chemistry. 315 - 329. 4. 1. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345451156&partnerID=MN8TOARS . 10.1006/niox.1997.0144 . Nitric Oxide - Biology and Chemistry
Modulation of Ca2+ channels by activation of adenosine A1 receptors in rat striatal glutamatergic nerve terminals
Ambrósio, A.F.; Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., 1996. Neuroscience Letters. 163 - 166. 3. 220. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030595814&partnerID=MN8TOARS . 10.1016/S0304-3940(96)13252-3 . Neuroscience Letters
Identification of a presynaptic kainate receptor which modules the exocytotic release of glutamate in rat hippocampal CA3 synaptosomes
Malva, J.; Carvalho, A.; Çarvalho, C., 1996. FASEB Journal. 3. 10. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748975701&partnerID=MN8TOARS . FASEB Journal
Domoic acid induces the release of glutamate in the rat hippocampal CA3 sub-region
Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., 1996. NeuroReport. 1330 - 1334. 7. 7. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029679826&partnerID=MN8TOARS . NeuroReport
Modulation oh intracellular ca2+ and exocytotic glulamate release by adhnosinh a1 rhchptor activation in the hippocampus
Carvalho, C.; Ambrócio, A.; Malva, J.; Carvlho, A., 1996. FASEB Journal. 3. 10. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-25744431605&partnerID=MN8TOARS . FASEB Journal
Characterization of voltage-sensitive Ca2+ channels activated by presynaptic glutamate receptor stimulation in hippocampus
Carvalho, C.M.; Malva, J.O.; Duarte, C.B.; Carvalho, A.P., 1995. Annals of the New York Academy of Sciences. 457 - 459. 757. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029129986&partnerID=MN8TOARS . 10.1111/j.1749-6632.1995.tb17505.x . Annals of the New York Academy of Sciences
Relation of [Ca2+]i to dopamine release in striatal synaptosomes: role of Ca2+ channels
Carvalho, C.M.; Ferreira, I.L.; Duarte, C.B.; Malva, J.O.; Tretter, L.; Adam-Vizi, V.; Carvalho, A.P., 1995. Brain Research. 234 - 244. 2. 669. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028839020&partnerID=MN8TOARS . Brain Research
A functionally active presynaptic high-affinity kainate receptor in the rat hippocampal CA3 subregion
Malva, J.O.; Ambrósio, A.F.; Cunha, R.A.; Ribeiro, J.A.; Carvalho, A.P.; Carvalho, C.M., 1995. Neuroscience Letters. 83 - 86. 2. 185. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028912732&partnerID=MN8TOARS . Neuroscience Letters
Modulation of dopamine and noradrenaline release and of intracellular Ca2+ concentration by presynaptic glutamate receptors in hippocampus
Malva, J.O.; Carvalho, A.P.; Carvalho, C.M., 1994. British Journal of Pharmacology. 1439 - 1447. 4. 113. 1994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027968075&partnerID=MN8TOARS . British Journal of Pharmacology
Action of antiestrogens on the (Ca2+ + Mg2+)-ATPase and Na+/Ca2+ exchange of brain cortex membranes
Malva, J.O.; Lopes, M.C.F.; Vale, M.G.P.; Carvalho, A.P., 1990. Biochemical Pharmacology. 1877 - 1884. 8. 40. 1990. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025196039&partnerID=MN8TOARS . Biochemical Pharmacology
5 135 out of 135 Publications
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