Metabolic Risk and Nutrition

Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice

Sousa, Adelaide; Azevedo, Rui; Costa, Vera Marisa; Oliveira, Sara; Preguiça, Inês; Viana, Sofia; Reis, Flávio; et al, 2023. Archives of Toxicology. 2643 - 2657. 10. 97. 2023. http://dx.doi.org/10.1007/s00204-023-03558-5 . 10.1007/s00204-023-03558-5 . published Archives of Toxicology

TNFR2 as a Potential Biomarker for Early Detection and Progression of CKD

Lousa, Irina; Reis, Flávio; Viana, Sofia; Vieira, Pedro; Vala, Helena; Belo, Luís; Santos-Silva, Alice, 2023. Biomolecules. 3. 13. 2023. http://dx.doi.org/10.3390/biom13030534 . 10.3390/biom13030534 . published Biomolecules

Are gut dysbiosis, barrier disruption, and endotoxemia related to adipose tissue dysfunction in metabolic disorders? Overview of the mechanisms involved

Rosendo-Silva, Daniela; Viana, Sofia; Carvalho, Eugénia; Reis, Flávio; Matafome, Paulo, 2023. Internal and Emergency Medicine. 1287 - 1302. 5. 18. 2023. http://dx.doi.org/10.1007/s11739-023-03262-3 . 10.1007/s11739-023-03262-3 . published Internal and Emergency Medicine

Analysis of Fluorescent-Stained Lipid Droplets with 3D Reconstruction for Hepatic Steatosis Assessment

Garcia, Karina; Alves, André; Ribeiro-Rodrigues, Teresa M.; Reis, Flávio; Viana, Sofia, 2023. Journal of Visualized Experiments. 196. 2023. http://dx.doi.org/10.3791/65206 . 10.3791/65206 . published Journal of Visualized Experiments

Reply to the Comment on “1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis”

Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana, Sofia; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al, 2023. Pharmacological Research. 191. 2023. http://dx.doi.org/10.1016/j.phrs.2022.106623 . 10.1016/j.phrs.2022.106623 . published Pharmacological Research

Impact of Dietary Sugars on Gut Microbiota and Metabolic Health

Garcia, Karina; Ferreira, Gonçalo; Reis, Flávio; Viana, Sofia, 2022. Diabetology. 549 - 560. 4. 3. 2022. http://dx.doi.org/10.3390/diabetology3040042 . 10.3390/diabetology3040042 . published Diabetology

Inflammatory biomarkers in staging of chronic kidney disease: elevated TNFR2 levels accompanies renal function decline

Lousa, Irina; Belo, Luís; Valente, Maria João; Rocha, Susana; Preguiça, Inês; Rocha-Pereira, Petronila; Beirão, Idalina; et al, 2022. Inflammation Research. 591 - 602. 5-6. 71. 2022. http://dx.doi.org/10.1007/s00011-022-01574-2 . 10.1007/s00011-022-01574-2 . published Inflammation Research

1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis

Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana, Sofia; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al, 2022. Pharmacological Research. 180. 2022. http://dx.doi.org/10.1016/j.phrs.2022.106151 . 10.1016/j.phrs.2022.106151 . published Pharmacological Research

Putative Biomarkers in Tears for Diabetic Retinopathy Diagnosis

Amorim, Madania; Martins, Beatriz; Caramelo, Francisco; Gonçalves, Conceição; Trindade, Grimalde; Simão, Jorge; Barreto, Patrícia; et al, 2022. Frontiers in Medicine. 9. 2022. http://dx.doi.org/10.3389/fmed.2022.873483 . 10.3389/fmed.2022.873483 . published Frontiers in Medicine

The Signaling Pathway of TNF Receptors: Linking Animal Models of Renal Disease to Human CKD

Lousa, Irina; Reis, Flávio; Santos-Silva, Alice; Belo, Luís, 2022. International Journal of Molecular Sciences. 6. 23. 2022. http://dx.doi.org/10.3390/ijms23063284 . 10.3390/ijms23063284 . published International Journal of Molecular Sciences

Defining milestones for the study of remyelination using the cuprizone mouse model: How early is early?

Palavra, Filipe; Viana, Sofia D.; Henriques, Sara; Dinis, João; Martins, João; Madeira, Maria H.; Santiago, Raquel; et al, 2022. Multiple Sclerosis and Related Disorders. 63. 2022. http://dx.doi.org/10.1016/j.msard.2022.103886 . 10.1016/j.msard.2022.103886 . published Multiple Sclerosis and Related Disorders

Subpopulations of High-Density Lipoprotein: Friends or Foes in Cardiovascular Disease Risk in Chronic Kidney Disease?

Susana Coimbra; Reis F; Maria João Valente; S. Rocha; Cristina Catarino; Petronila Rocha-Pereira; Maria Sameiro-Faria; et al, 2021. Biomedicines. 2021. https://www.mdpi.com/2227-9059/9/5/554 . 10.3390/biomedicines9050554 . Biomedicines

Editorial: Combating Redox Imbalance-Associated Complications With Natural Products

Pandey, A.K.; Kumar, S.; Reis, F., 2021. Frontiers in Pharmacology. 12. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85121004209&partnerID=MN8TOARS . 10.3389/fphar.2021.802750 . Frontiers in Pharmacology

Unhealthy lifestyles, environment, well-being and health capability in rural neighbourhoods: a community-based cross-sectional study

Azul, A.M.; Almendra, R.; Quatorze, M.; Loureiro, A.; Reis, F.; Tavares, R.; Mota-Pinto, A.; et al, 2021. BMC public health. 1628 - 1628. 1. 21. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85115819445&partnerID=MN8TOARS . 10.1186/s12889-021-11661-4 . BMC public health

A selective p53 activator and anticancer agent to improve colorectal cancer therapy

Ramos, H.; Soares, M.I.L.; Silva, J.; Raimundo, L.; Calheiros, J.; Gomes, C.; Reis, F.; et al, 2021. Cell Reports. 2. 35. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85104050337&partnerID=MN8TOARS . 10.1016/j.celrep.2021.108982 . Cell Reports

Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics

Sara Nunes; Sofia D. Viana; Inês Preguiça; André Alves; R. Fernandes; Teodoro, J.S.; Patrícia Matos; et al, 2021. Nutrients. 2021. https://www.mdpi.com/2072-6643/13/12/4192 . 10.3390/nu13124192 . Nutrients

Assessing Scientific Soundness and Translational Value of Animal Studies on DPP4 Inhibitors for Treating Type 2 Diabetes Mellitus

Nuno Henrique Franco; Sónia Miranda; Nóra Kovács; Attila Nagy; Bùi Qu¿c Thi¿n; Reis F; Orsolya Varga, 2021. Biology. 2021. https://www.mdpi.com/2079-7737/10/2/155 . 10.3390/biology10020155 . Biology

Blueberry as An Attractive Functional Fruit to Prevent (Pre)Diabetes Progression

Sara Nunes; Pedro Vieira; Pedro Gomes; Sofia Domingues Viana; Reis F, 2021. Antioxidants. 2021. https://www.mdpi.com/2076-3921/10/8/1162 . 10.3390/antiox10081162 . Antioxidants

Diet-induced rodent models of obesity-related metabolic disorders-A guide to a translational perspective.

Preguiça I; Alves A; Nunes S; Fernandes R; Gomes P; Viana SD; Reis F, 2020. Obesity reviews : an official journal of the International Association for the Study of Obesity. 2020. http://europepmc.org/abstract/med/32691524 . 10.1111/obr.13081 . Obesity reviews : an official journal of the International Association for the Study of Obesity

Diet-Induced Rodent Models of Diabetic Peripheral Neuropathy, Retinopathy and Nephropathy

Reis, Flávio, 2020. Nutrients. 2020. http://dx.doi.org/10.3390/nu12010250 . 10.3390/nu12010250 . Nutrients

New Potential Biomarkers for Chronic Kidney Disease Management—A Review of the Literature

Irina Lousa; Reis F; Idalina Beirão; Rui Alves; Luís Belo; Alice Santos-Silva, 2020. International Journal of Molecular Sciences. 2020. https://www.mdpi.com/1422-0067/22/1/43 . 10.3390/ijms22010043 . International Journal of Molecular Sciences

Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats

Sara Nunes; Sofia D. Viana; Inês Preguiça; André Alves; R. Fernandes; Teodoro, J.S.; Artur Figueirinha; et al, 2020. Pharmaceutics. 2020. https://www.mdpi.com/1999-4923/12/11/1094 . 10.3390/pharmaceutics12111094 . Pharmaceutics

Extracellular Vesicles and MicroRNA: Putative Role in Diagnosis and Treatment of Diabetic Retinopathy

Beatriz Martins; Madania Amorim; Reis F; António F Ambrósio; R. Fernandes, 2020. Antioxidants. 2020. https://www.mdpi.com/2076-3921/9/8/705 . 10.3390/antiox9080705 . Antioxidants

Crescent-Like Lesions as an Early Signature of Nephropathy in a Rat Model of Prediabetes Induced by a Hypercaloric Diet

Sara Nunes; André Alves; Inês Preguiça; Adelaide Barbosa; Pedro Vieira; Fernando Mendes; Diana Martins; Sofia D. Viana; Reis F, 2020. Nutrients. 2020. https://www.mdpi.com/2072-6643/12/4/881 . 10.3390/nu12040881 . Nutrients

Gut Microbiota Dysbiosis–Immune Hyperresponse–Inflammation Triad in Coronavirus Disease 2019 (COVID-19): Impact of Pharmacological and Nutraceutical Approaches

Carolina Ferreira; Sofia D. Viana; Reis F, 2020. Microorganisms. 2020. https://www.mdpi.com/2076-2607/8/10/1514 . 10.3390/microorganisms8101514 . Microorganisms

Is Gut Microbiota Dysbiosis a Predictor of Increased Susceptibility to Poor Outcome of COVID-19 Patients? An Update

Carolina Ferreira; Sofia D. Viana; Reis F, 2020. Microorganisms. 2020. https://www.mdpi.com/2076-2607/9/1/53 . 10.3390/microorganisms9010053 . Microorganisms

Lactation as a programming window for metabolic syndrome.

Picó C; Reis F; Egas C; Mathias P; Matafome P, 2020. European journal of clinical investigation. 2020. http://europepmc.org/abstract/med/33350459 . 10.1111/eci.13482 . European journal of clinical investigation

ACE2 imbalance as a key player for the poor outcomes in COVID-19 patients with age-related comorbidities - Role of gut microbiota dysbiosis.

Viana SD; Nunes S; Reis F, 2020. Ageing research reviews. 2020. http://europepmc.org/abstract/med/32683039 . 10.1016/j.arr.2020.101123 . Ageing research reviews

mTOR Signaling in Cardiometabolic Disease, Cancer, and Aging 2018.

Das A; Reis F; Mishra PK, 2019. Oxidative medicine and cellular longevity. 2019. http://europepmc.org/abstract/med/30863483 . 10.1155/2019/9692528 . Oxidative medicine and cellular longevity

Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases.

Gomes P; Leal H; Mendes AF; Reis F; Cavadas C, 2019. Trends in pharmacological sciences. 2019. http://europepmc.org/abstract/med/31704173 . 10.1016/j.tips.2019.09.003 . Trends in pharmacological sciences

The Protective Role of Adiponectin for Lipoproteins in End-Stage Renal Disease Patients: Relationship with Diabetes and Body Mass Index.

Coimbra S; Reis F; Nunes S; Viana S; Valente MJ; Rocha S; Catarino C; et al, 2019. Oxidative medicine and cellular longevity. 2019. http://europepmc.org/abstract/med/30911344 . 10.1155/2019/3021785 . Oxidative medicine and cellular longevity

Development of a Healthy Lifestyle Assessment Toolkit for the General Public.

Reis F; Sá-Moura B; Guardado D; Couceiro P; Catarino L; Mota-Pinto A; Veríssimo MT; et al, 2019. Frontiers in medicine. 2019. http://europepmc.org/abstract/med/31316985 . 10.3389/fmed.2019.00134 . Frontiers in medicine

The dipeptidyl peptidase 4 inhibitor sitagliptin improves oxidative stress and ameliorates glomerular lesions in a rat model of type 1 diabetes.

Marques C; Gonçalves A; Pereira PMR; Almeida D; Martins B; Fontes-Ribeiro C; Reis F; Fernandes R, 2019. Life sciences. 2019. http://europepmc.org/abstract/med/31398418 . 10.1016/j.lfs.2019.116738 . Life sciences

Beneficial Effects of Dietary Polyphenols on Gut Microbiota and Strategies to Improve Delivery Efficiency

Amit Kumar Singh; Célia Cabral; Ramesh Kumar; Risha Ganguly; Harvesh Kumar Rana; ASHUTOSH GUPTA; Maria Rosaria Lauro; et al, 2019. Nutrients. 2019. https://www.mdpi.com/2072-6643/11/9/2216 . 10.3390/nu11092216 . Nutrients

The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders.

Gomes P; Viana SD; Nunes S; Rolo AP; Palmeira CM; Reis F, 2019. Ageing research reviews. 2019. http://europepmc.org/abstract/med/31740222 . 10.1016/j.arr.2019.100983 . Ageing research reviews

SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma.

Gomes S; Bosco B; Loureiro JB; Ramos H; Raimundo L; Soares J; Nazareth N; et al, 2019. Cancers. 2019. http://europepmc.org/abstract/med/31405179 . 10.3390/cancers11081151 . Cancers

Therapeutic Options Targeting Oxidative Stress, Mitochondrial Dysfunction and Inflammation to Hinder the Progression of Vascular Complications of Diabetes.

Teodoro JS; Nunes S; Rolo AP; Reis F; Palmeira CM, 2018. Frontiers in physiology. 2018. http://europepmc.org/abstract/med/30705633 . 10.3389/fphys.2018.01857 . Frontiers in physiology

Weight loss achieved by bariatric surgery modifies high-density lipoprotein subfractions and low-density lipoprotein oxidation towards atheroprotection.

Coimbra S; Reis F; Ferreira C; Nunes S; Viana S; Catarino A; Rocha-Pereira P; et al, 2018. Clinical biochemistry. 2018. http://europepmc.org/abstract/med/30342017 . 10.1016/j.clinbiochem.2018.10.007 . Clinical biochemistry

Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy.

Fernandes R; Viana SD; Nunes S; Reis F, 2018. Biochimica et biophysica acta. Molecular basis of disease. 2018. http://europepmc.org/abstract/med/30287404 . 10.1016/j.bbadis.2018.09.032 . Biochimica et biophysica acta. Molecular basis of disease

Subtle thinning of retinal layers without overt vascular and inflammatory alterations in a rat model of prediabetes

Alves, M.R.P.; Boia, R.; Campos, E.J.; Martins, J.; Nunes, S.; Madeira, M.H.; Santiago, A.R.; et al, 2018. Molecular Vision. 353 - 366. 24. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050808197&partnerID=MN8TOARS . Molecular Vision

Therapeutic Use of mTOR Inhibitors in Renal Diseases: Advances, Drawbacks, and Challenges.

Viana SD; Reis F; Alves R, 2018. Oxidative medicine and cellular longevity. 2018. http://europepmc.org/abstract/med/30510618 . 10.1155/2018/3693625 . Oxidative medicine and cellular longevity

Subtle thinning of retinal layers without overt vascular and inflammatory alterations in a rat model of prediabetes.

Alves MRP; Boia R; Campos EJ; Martins J; Nunes S; Madeira MH; Santiago AR; et al, 2018. Molecular vision. 2018. http://europepmc.org/abstract/med/29853770 . Molecular vision

Influence of the 6-month physical activity programs on renal function in obese boys.

Lousa I; Nascimento H; Rocha S; Catarino C; Reis F; Rêgo C; Santos-Silva A; et al, 2018. Pediatric research. 2018. http://europepmc.org/abstract/med/29638229 . 10.1038/pr.2018.15 . Pediatric research

Therapeutic and nutraceutical potential of rosmarinic acid—Cytoprotective properties and pharmacokinetic profile

Nunes, S.; Madureira, A.R.; Campos, D.; Sarmento, B.; Gomes, A.M.; Pintado, M.; Reis, F., 2017. Critical Reviews in Food Science and Nutrition. 1799 - 1806. 9. 57. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014885468&partnerID=MN8TOARS . 10.1080/10408398.2015.1006768 . Critical Reviews in Food Science and Nutrition

DIMP53-1: A novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties.

Soares J; Espadinha M; Raimundo L; Ramos H; Gomes AS; Gomes S; Loureiro JB; et al, 2017. 2017. http://europepmc.org/abstract/med/28296148 . 10.1002/1878-0261.12051 .

Solid lipid nanoparticles as oral delivery systems of phenolic compounds: Overcoming pharmacokinetic limitations for nutraceutical applications

Nunes, S.; Madureira, A.R.; Campos, D.; Sarmento, B.; Gomes, A.M.; Pintado, M.; Reis, F., 2017. Critical Reviews in Food Science and Nutrition. 1863 - 1873. 9. 57. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014884555&partnerID=MN8TOARS . 10.1080/10408398.2015.1031337 . Critical Reviews in Food Science and Nutrition

Renoprotective Effects of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin: A Review in Type 2 Diabetes.

Reis, Flávio, 2017. Journal of diabetes research. 2017. http://europepmc.org/abstract/med/29098166 . 10.1155/2017/5164292 . Journal of diabetes research

Recent Advances and Challenges of mTOR Inhibitors Use in the Treatment of Patients with Tuberous Sclerosis Complex.

Palavra F; Robalo C; Reis F, 2017. 2017. http://europepmc.org/abstract/med/28386314 . 10.1155/2017/9820181 .

mTOR Signaling in Cardiometabolic Disease, Cancer, and Aging.

Reis, Flávio, 2017. Oxidative medicine and cellular longevity. 2017. http://europepmc.org/abstract/med/28770023 . 10.1155/2017/6018675 . Oxidative medicine and cellular longevity

Glucose and Lipid Dysmetabolism in a Rat Model of Prediabetes Induced by a High-Sucrose Diet.

Reis, Flávio, 2017. Nutrients. 2017. http://europepmc.org/abstract/med/28635632 . 10.3390/nu9060638 . Nutrients

Therapeutic strategies targeting oxidative stress to improve dyslipidemia and left ventricular hypertrophy.

Reis, Flávio, 2017. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2017. http://europepmc.org/abstract/med/28826936 . 10.1016/j.repc.2017.07.003 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Impaired renal endothelial nitric oxide synthase and reticulocyte production as modulators of hypertension induced by rHuEPO in the rat.

Ribeiro S; Garrido P; Fernandes J; Vala H; Rocha-Pereira P; Costa E; Belo L; Reis F; Santos-Silva A, 2016. 2016. http://europepmc.org/abstract/med/26924494 . 10.1016/j.lfs.2016.02.088 .

Safety profile of solid lipid nanoparticles loaded with rosmarinic acid for oral use: in vitro and animal approaches.

Madureira AR; Nunes S; Campos DA; Fernandes JC; Marques C; Zuzarte M; Gullón B; et al, 2016. 2016. http://europepmc.org/abstract/med/27536103 . 10.2147/ijn.s104623 .

A fast and reliable method for GHB quantitation in whole blood by GC-MS/MS (TQD) for forensic purposes.

Castro AL; Tarelho S; Dias M; Reis F; Teixeira HM, 2016. 2016. http://europepmc.org/abstract/med/26678181 . 10.1016/j.jpba.2015.11.038 .

Obesity and brain inflammation: a focus on multiple sclerosis.

Palavra F; Almeida L; Ambrósio AF; Reis F, 2016. 2016. http://europepmc.org/abstract/med/26783119 . 10.1111/obr.12363 .

Pathological and molecular mechanisms underlying resistance to recombinant human erythropoietin therapy in the remnant kidney rat model of chronic kidney disease associated anemia.

Ribeiro S; Garrido P; Fernandes J; Vala H; Rocha-Pereira P; Costa E; Belo L; Reis F; Santos-Silva A, 2016. 2016. http://europepmc.org/abstract/med/27039028 .

Liver iron is a major regulator of hepcidin gene expression via BMP/SMAD pathway in a rat model of chronic renal failure under treatment with high rHuEPO doses.

Ribeiro S; Garrido P; Fernandes J; Rocha-Pereira P; Costa E; Belo L; Reis F; Santos-Silva A, 2016. 2016. http://europepmc.org/abstract/med/26990350 . 10.1002/biof.1275 .

Recombinant human erythropoietin-induced erythropoiesis regulates hepcidin expression over iron status in the rat.

Ribeiro S; Garrido P; Fernandes J; Rocha S; Rocha-Pereira P; Costa E; Belo L; Reis F; Santos-Silva A, 2016. 2016. http://europepmc.org/abstract/med/27282570 . 10.1016/j.bcmd.2016.04.008 .

Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells.

Ferreira-Teixeira M; Paiva-Oliveira D; Parada B; Alves V; Sousa V; Chijioke O; Münz C; et al, 2016. 2016. http://europepmc.org/abstract/med/27769244 .

Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes.

García-Casarrubios E; de Moura C; Arroba AI; Pescador N; Calderon-Dominguez M; Garcia L; Herrero L; et al, 2016. 2016. http://europepmc.org/abstract/med/27686967 . 10.1016/j.bbalip.2016.09.016 .

Comparison of endogenous GHB concentrations in blood and hair in death cases with emphasis on the post mortem interval.

Castro AL; Tarelho S; Dias M; Reis F; Teixeira HM, 2016. 2016. http://europepmc.org/abstract/med/26846768 .

Pathological and molecular mechanisms underlying resistance to recombinant human erythropoietin therapy in the remnant kidney rat model of chronic kidney disease associated anemia

Ribeiro, S.; Garrido, P.; Fernandes, J.; Vala, H.; Rocha-Pereira, P.; Costa, E.; Belo, L.; Reis, F.; Santos-Silva, A., 2016. Biochimie. 150 - 162. 125. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964388884&partnerID=MN8TOARS . 10.1016/j.biochi.2016.03.012 . Biochimie

The incretin system ABCs in obesity and diabetes - novel therapeutic strategies for weight loss and beyond.

João AL; Reis F; Fernandes R, 2016. 2016. http://europepmc.org/abstract/med/27125902 . 10.1111/obr.12421 .

High sucrose consumption induces memory impairment in rats associated with electrophysiological modifications but not with metabolic changes in the hippocampus.

Lemos C; Rial D; Gonçalves FQ; Pires J; Silva HB; Matheus FC; da Silva AC; et al, 2016. 2016. http://europepmc.org/abstract/med/26704636 . 10.1016/j.neuroscience.2015.12.018 .

Iron therapy in chronic kidney disease: Recent changes, benefits and risks

Ribeiro, S.; Belo, L.; Reis, F.; Santos-Silva, A., 2016. Blood Reviews. 65 - 72. 1. 30. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960312577&partnerID=MN8TOARS . 10.1016/j.blre.2015.07.006 . Blood Reviews

Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells

Ferreira-Teixeira, M.; Paiva-Oliveira, D.; Parada, B.; Alves, V.; Sousa, V.; Chijioke, O.; Münz, C.; et al, 2016. BMC Medicine. 1. 14. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84992153376&partnerID=MN8TOARS . 10.1186/s12916-016-0715-2 . BMC Medicine

Comparison of endogenous GHB concentrations in blood and hair in death cases with emphasis on the post mortem interval

Castro, A.L.; Tarelho, S.; Dias, M.; Reis, F.; Teixeira, H.M., 2016. International Journal of Legal Medicine. 959 - 965. 4. 130. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957591999&partnerID=MN8TOARS . 10.1007/s00414-016-1321-8 . International Journal of Legal Medicine

Cyclosporine a-induced nephrotoxicity is ameliorated by dose reduction and conversion to sirolimus in the rat

Sereno, J.; Vala, H.; Nunes, S.; Rocha-Pereira, P.; Carvalho, E.; Alves, R.; Teixeira, F.; Reis, F., 2015. Journal of Physiology and Pharmacology. 285 - 299. 2. 66. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84927565139&partnerID=MN8TOARS . Journal of Physiology and Pharmacology

Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule.

Soares J; Raimundo L; Pereira NA; Monteiro Â; Gomes S; Bessa C; Pereira C; et al, 2015. 2015. http://europepmc.org/abstract/med/26735173 . 10.18632/oncotarget.6775 .

Characterization of solid lipid nanoparticles produced with carnauba wax for rosmarinic acid oral delivery

Madureira, Ana Raquel; Campos, Débora A.; Fonte, Pedro; Nunes, Sara; Reis, Flávio; Gomes, Ana Maria; Sarmento, Bruno; Pintado, Maria Manuela, 2015. RSC Advances. 22665 - 22673. 29. 5. 2015. http://dx.doi.org/10.1039/c4ra15802d . 10.1039/c4ra15802d . published RSC Advances

Iron therapy in chronic kidney disease: Recent changes, benefits and risks.

Ribeiro S; Belo L; Reis F; Santos-Silva A, 2015. 2015. http://europepmc.org/abstract/med/26342303 .

The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A "Me Too" or "the Special One" Antidiabetic Class?

Godinho R; Mega C; Teixeira-de-Lemos E; Carvalho E; Teixeira F; Fernandes R; Reis F, 2015. 2015. http://europepmc.org/abstract/med/26075286 . 10.1155/2015/806979 .

Cyclosporine A-induced nephrotoxicity is ameliorated by dose reduction and conversion to sirolimus in the rat.

Sereno J; Vala H; Nunes S; Rocha-Pereira P; Carvalho E; Alves R; Teixeira F; Reis F, 2015. 2015. http://europepmc.org/abstract/med/25903959 .

Resistance to Recombinant Human Erythropoietin Therapy in a Rat Model of Chronic Kidney Disease Associated Anemia.

Garrido P; Ribeiro S; Fernandes J; Vala H; Rocha-Pereira P; Bronze-da-Rocha E; Belo L; et al, 2015. 2015. http://europepmc.org/abstract/med/26712750 . 10.3390/ijms17010028 .

Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model.

Garrido P; Ribeiro S; Fernandes J; Vala H; Bronze-da-Rocha E; Rocha-Pereira P; Belo L; et al, 2015. 2015. http://europepmc.org/abstract/med/25867633 . 10.1371/journal.pone.0124048 .

Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an in vivo rat model.

Sereno J; Rodrigues-Santos P; Vala H; Rocha-Pereira P; Alves R; Fernandes J; Santos-Silva A; et al, 2014. 2014. http://europepmc.org/abstract/med/24853130 . 10.3390/ijms15058979 .

Potential cardiovascular risk protection of bilirubin in end-stage renal disease patients under hemodialysis.

do Sameiro-Faria M; Kohlova M; Ribeiro S; Rocha-Pereira P; Teixeira L; Nascimento H; Reis F; et al, 2014. 2014. http://europepmc.org/abstract/med/25276769 . 10.1155/2014/175286 .

Gamma-hydroxybutyric acid endogenous production and post-mortem behaviour - the importance of different biological matrices, cut-off reference values, sample collection and storage conditions.

Castro AL; Dias M; Reis F; Teixeira HM, 2014. 2014. http://europepmc.org/abstract/med/25287794 . 10.1016/j.jflm.2014.07.008 .

Conversion to sirolimus ameliorates cyclosporine-induced nephropathy in the rat: focus on serum, urine, gene, and protein renal expression biomarkers.

Sereno J; Nunes S; Rodrigues-Santos P; Vala H; Rocha-Pereira P; Fernandes J; Santos-Silva A; Teixeira F; Reis F, 2014. 2014. http://europepmc.org/abstract/med/24971338 . 10.1155/2014/576929 .

Aging is Associated with Impaired Renal Function, INF-gamma Induced Inflammation and with Alterations in Iron Regulatory Proteins Gene Expression.

Costa E; Fernandes J; Ribeiro S; Sereno J; Garrido P; Rocha-Pereira P; Coimbra S; et al, 2014. 2014. http://europepmc.org/abstract/med/25489488 . 10.14366/AD.2014.0500356 .

Iron as the key modulator of hepcidin expression in erythroid antibody-mediated hypoplasia.

Fernandes JC; Garrido P; Ribeiro S; Rocha-Pereira P; Bronze-da-Rocha E; Belo L; Costa E; Reis F; Santos-Silva A, 2014. 2014. http://europepmc.org/abstract/med/25580431 . 10.1155/2014/421304 .

Sitagliptin prevents inflammation and apoptotic cell death in the kidney of type 2 diabetic animals.

Marques C; Mega C; Gonçalves A; Rodrigues-Santos P; Teixeira-Lemos E; Teixeira F; Fontes-Ribeiro C; Reis F; Fernandes R, 2014. 2014. http://europepmc.org/abstract/med/24817793 . 10.1155/2014/538737 .

Molecular mechanisms underlying the effects of cyclosporin A and sirolimus on glucose and lipid metabolism in liver, skeletal muscle and adipose tissue in an in vivo rat model.

Fuhrmann A; Lopes P; Sereno J; Pedro J; Espinoza DO; Pereira MJ; Reis F; Eriksson JW; Carvalho E, 2014. 2014. http://europepmc.org/abstract/med/24462915 . 10.1016/j.bcp.2014.01.020 .

Haptoglobin 2-2 phenotype is associated with decreased serum iron levels in endstage renal disease patients resistant to rhEPO therapy.

Martins F; Catarino C; Rocha-Pereira P; Reis F; Sameiro-Faria M; Miranda V; Belo L; et al, 2014. 2014. http://europepmc.org/abstract/med/24974683 .

Short and long term in vivo effects of Cyclosporine A and Sirolimus on genes and proteins involved in lipid metabolism in Wistar rats.

Lopes PC; Fuhrmann A; Sereno J; Espinoza DO; Pereira MJ; Eriksson JW; Reis F; Carvalho E, 2014. 2014. http://europepmc.org/abstract/med/24656168 . 10.1016/j.metabol.2014.02.004 .

Haptoglobin 2-2 phenotype is associated with decreased serum iron levels in endstage renal disease patients resistant to rhEPO therapy

Martins, F.; Catarino, C.; Rocha-Pereira, P.; Reis, F.; Sameiro-Faria, M.; Miranda, V.; Belo, L.; et al, 2014. British Journal of Biomedical Science. 79 - 85. 2. 71. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906561873&partnerID=MN8TOARS . 10.1080/09674845.2014.11669969 . British Journal of Biomedical Science

Cyclosporine A enhances gluconeogenesis while sirolimus impairs insulin signaling in peripheral tissues after 3 weeks of treatment.

Lopes PC; Fuhrmann A; Carvalho F; Sereno J; Santos MR; Pereira MJ; Eriksson JW; Reis F; Carvalho E, 2014. 2014. http://europepmc.org/abstract/med/24960264 . 10.1016/j.bcp.2014.06.014 .

Remyelination in multiple sclerosis – how close are we?

Reis, Flávio, 2014. 2014. https://www.omicsonline.org/open-access/remyelination-in-multiple-sclerosis-how-close-are-we-2155-9562-5-192.php?aid=24044 . 10.4172/2155-9562.1000192 .

Dipeptidyl peptidase-IV inhibition prevents blood-retinal barrier breakdown, inflammation and neuronal cell death in the retina of type 1 diabetic rats.

Gonçalves A; Marques C; Leal E; Ribeiro CF; Reis F; Ambrósio AF; Fernandes R, 2014. 2014. http://europepmc.org/abstract/med/24769045 . 10.1016/j.bbadis.2014.04.013 .

Sitagliptin prevents aggravation of endocrine and exocrine pancreatic damage in the Zucker Diabetic Fatty rat - focus on amelioration of metabolic profile and tissue cytoprotective properties.

Mega C; Vala H; Rodrigues-Santos P; Oliveira J; Teixeira F; Fernandes R; Reis F; de Lemos ET, 2014. 2014. http://europepmc.org/abstract/med/24650557 . 10.1186/1758-5996-6-42 .

Circulating cell-free DNA levels in hemodialysis patients and its association with inflammation, iron metabolism, and rhEPO doses.

Kohlova M; Ribeiro S; do Sameiro-Faria M; Rocha-Pereira P; Fernandes J; Reis F; Miranda V; et al, 2013. 2013. http://europepmc.org/abstract/med/23679088 . 10.1111/hdi.12055 .

Vascular access versus the effect of statins on inflammation and fibrinolysis in renal dialysis patients.

do Sameiro Faria M; Ribeiro S; Rocha-Pereira P; Miranda V; Quintanilha A; Reis F; Costa E; Belo L; Santos-Silva A, 2013. 2013. http://europepmc.org/abstract/med/23661140 . 10.5301/jva.5000132 .

Effects of cyclosporine and sirolimus on insulin-stimulated glucose transport and glucose tolerance in a rat model

Lopes, P.; Fuhrmann, A.; Sereno, J.; Pereira, M.J.; Nunes, P.; Pedro, J.; Melão, A.; Reis, F.; Carvalho, E., 2013. Transplantation Proceedings. 1142 - 1148. 3. 45. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876870991&partnerID=MN8TOARS . 10.1016/j.transproceed.2013.02.009 . Transplantation Proceedings

Early cardiac changes in a rat model of prediabetes: Brain natriuretic peptide overexpression seems to be the best marker

Nunes, S.; Soares, E.; Fernandes, J.; Viana, S.; Carvalho, E.; Pereira, F.C.; Reis, F., 2013. Cardiovascular Diabetology. 1. 12. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874618884&partnerID=MN8TOARS . 10.1186/1475-2840-12-44 . Cardiovascular Diabetology

Risk Factors for Mortality in Hemodialysis Patients: Two-Year Follow-Up Study

Sameiro-Faria, Maria do; Ribeiro, Sandra; Costa, Elísio; Mendonça, Denisa; Teixeira, Laetitia; Rocha-Pereira, Petronila; Fernandes, João; et al, 2013. Disease Markers. 791 - 798. 35. 2013. http://dx.doi.org/10.1155/2013/518945 . 10.1155/2013/518945 . published Disease Markers

Letter to the editor: A potential mechanism for the pathogenesis of psoriasis vulgaris

Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Rocha, S.; Quintanilha, A.; Figueiredo, A.; et al, 2013. International Journal of Dermatology. 1429 - 1432. 11. 52. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886750937&partnerID=MN8TOARS . 10.1111/j.1365-4632.2011.05249.x . International Journal of Dermatology

Spatial memory impairments in a prediabetic rat model

Soares, E.; Prediger, R.D.; Nunes, S.; Castro, A.A.; Viana, S.D.; Lemos, C.; De Souza, C.M.; et al, 2013. Neuroscience. 565 - 577. 250. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882959210&partnerID=MN8TOARS . 10.1016/j.neuroscience.2013.07.055 . Neuroscience

Body mass index and resistance to recombinant human erythropoietin therapy in maintenance hemodialysis patients

Do Sameiro-Faria, M.; Ribeiro, S.; Rocha-Pereira, P.; Fernandes, J.; Reis, F.; Bronze-Da-Rocha, E.; Miranda, V.; et al, 2013. Renal Failure. 1392 - 1398. 10. 35. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885895511&partnerID=MN8TOARS . 10.3109/0886022X.2013.828267 . Renal Failure

New markers of early cardiovascular risk in multiple sclerosis patients: Oxidized-LDL correlates with clinical staging

Palavra, F.; Marado, D.; Mascarenhas-Melo, F.; Sereno, J.; Teixeira-Lemos, E.; Nunes, C.C.; Gonçalves, G.; Teixeira, F.; Reis, F., 2013. Disease Markers. 341 - 348. 5. 34. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878866094&partnerID=MN8TOARS . 10.3233/DMA-130979 . Disease Markers

Serum and renal tissue markers of nephropathy in rats under immunosuppressive therapy: Cyclosporine versus sirolimus

Sereno, J.; Parada, B.; Rodrigues-Santos, P.; Lopes, P.C.; Carvalho, E.; Vala, H.; Teixeira-Lemos, E.; et al, 2013. Transplantation Proceedings. 1149 - 1156. 3. 45. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876882818&partnerID=MN8TOARS . 10.1016/j.transproceed.2013.02.085 . Transplantation Proceedings

Diabetes abrogates sex differences and aggravates cardiometabolic risk in postmenopausal women

Mascarenhas-Melo, F.; Marado, D.; Palavra, F.; Sereno, J.; Coelho, T.; Pinto, R.; Teixeira-Lemos, E.; Teixeira, F.; Reis, F., 2013. Cardiovascular Diabetology. 1. 12. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875878475&partnerID=MN8TOARS . 10.1186/1475-2840-12-61 . Cardiovascular Diabetology

Omega-3 fatty acids inhibit tumor growth in a rat model of bladder cancer

Parada, B.; Reis, F.; Cerejo, R.; Garrido, P.; Sereno, J.; Xavier-Cunha, M.; Neto, P.; et al, 2013. BioMed Research International. 2013. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880164934&partnerID=MN8TOARS . 10.1155/2013/368178 . BioMed Research International

Implication of low HDL-c levels in patients with average LDL-c levels: A focus on oxidized LDL, large HDL subpopulation, and adiponectin

Mascarenhas-Melo, F.; Sereno, J.; Teixeira-Lemos, E.; Marado, D.; Palavra, F.; Pinto, R.; Rocha-Pereira, P.; Teixeira, F.; Reis, F., 2013. Mediators of Inflammation. 2013. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887385092&partnerID=MN8TOARS . 10.1155/2013/612038 . Mediators of Inflammation

Markers of increased cardiovascular risk in postmenopausal women: Focus on oxidized-LDL and HDL subpopulations

Mascarenhas-Melo, F.; Sereno, J.; Teixeira-Lemos, E.; Ribeiro, S.; Rocha-Pereira, P.; Cotterill, E.; Teixeira, F.; Reis, F., 2013. Disease Markers. 19 - 30. 2. 35. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882302842&partnerID=MN8TOARS . 10.1155/2013/724706 . Disease Markers

Emergent biomarkers of residual cardiovascular risk in patients with low HDL-c and/or high triglycerides and average LDL-c concentrations: Focus on HDL subpopulations, oxidized LDL, adiponectin, and uric acid

Mascarenhas-Melo, F.; Palavra, F.; Marado, D.; Sereno, J.; Teixeira-Lemos, E.; Freitas, I.; Isabel-Mendonça, M.; et al, 2013. The Scientific World Journal. 2013. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888877710&partnerID=MN8TOARS . 10.1155/2013/387849 . The Scientific World Journal

Diabetic encephalopathy: The role of oxidative stress and inflammation in type 2 diabetes

Soares, E.; Nunes, S.; Reis, F.; Pereira, F.C., 2012. International Journal of Interferon, Cytokine and Mediator Research. 75 - 85. 1. 4. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866868197&partnerID=MN8TOARS . 10.2147/IJICMR.S29322 . International Journal of Interferon, Cytokine and Mediator Research

Protective effects of the dipeptidyl peptidase IV inhibitor sitagliptin in the blood-retinal barrier in a type 2 diabetes animal model

Gonçalves, A.; Leal, E.; Paiva, A.; Teixeira Lemos, E.; Teixeira, F.; Ribeiro, C.F.; Reis, F.; Ambrósio, A.F.; Fernandes, R., 2012. Diabetes, Obesity and Metabolism. 454 - 463. 5. 14. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859444000&partnerID=MN8TOARS . 10.1111/j.1463-1326.2011.01548.x . Diabetes, Obesity and Metabolism

Dexmedetomidine: Current Role in Anesthesia and Intensive Care | Dexmedetomidina: Papel Atual em Anestesia e Cuidados Intensivos

Afonso, J.; Reis, F., 2012. Revista Brasileira de Anestesiologia. 118 - 133. 1. 62. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855895511&partnerID=MN8TOARS . 10.1016/S0034-7094(12)70110-1 . Revista Brasileira de Anestesiologia

The role of inflammation in diabetic cardiomyopathy

Nunes, S.; Soares, E.; Pereira, F.; Reis, F., 2012. International Journal of Interferon, Cytokine and Mediator Research. 59 - 73. 1. 4. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864849181&partnerID=MN8TOARS . 10.2147/IJICMR.S21679 . International Journal of Interferon, Cytokine and Mediator Research

Regular physical exercise as a strategy to improve antioxidant and anti-inflammatory status: Benefits in type 2 diabetes mellitus

Teixeira De Lemos, E.; Oliveira, J.; Páscoa Pinheiro, J.; Reis, F., 2012. Oxidative Medicine and Cellular Longevity. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866164347&partnerID=MN8TOARS . 10.1155/2012/741545 . Oxidative Medicine and Cellular Longevity

Cardiorenal benefits of early versus late cyclosporine to sirolimus conversion in a rat model

Sereno, J.; Romão, A.M.; Parada, B.; Lopes, P.; Carvalho, E.; Teixeira, F.; Reis, F., 2012. Journal of Pharmacology and Pharmacotherapeutics. 143 - 148. 2. 3. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878801249&partnerID=MN8TOARS . 10.4103/0976-500X.95513 . Journal of Pharmacology and Pharmacotherapeutics

Cardiac antiapoptotic and proproliferative effect of recombinant human erythropoietin in a moderate stage of chronic renal failure in the rat

Teixeira, M.; Rodrigues-Santos, P.; Garrido, P.; Costa, E.; Parada, B.; Sereno, J.; Alves, R.; et al, 2012. Journal of Pharmacy and Bioallied Sciences. 76 - 83. 1. 4. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856859990&partnerID=MN8TOARS . 10.4103/0975-7406.92743 . Journal of Pharmacy and Bioallied Sciences

Major determinants of BMP-2 serum levels in hemodialysis patients

Costa, E.; Coimbra, J.; Catarino, C.; Ribeiro, S.; Reis, F.; Nascimento, H.; Fernandes, J.; et al, 2012. Renal Failure. 1355 - 1358. 10. 34. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867720386&partnerID=MN8TOARS . 10.3109/0886022X.2012.725289 . Renal Failure

Inhibition of bladder tumor growth by chitooligosaccharides in an experimental carcinogenesis model

Fernandes, J.C.; Sereno, J.; Garrido, P.; Parada, B.; Cunha, M.F.X.; Reis, F.; Pintado, M.E.; Santos-Silva, A., 2012. Marine Drugs. 2661 - 2675. 12. 10. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871733767&partnerID=MN8TOARS . 10.3390/md10122661 . Marine Drugs

Erythroid disturbances before and after treatment of Portuguese psoriasis vulgaris patients: A cross-sectional and longitudinal study

Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Rocha, S.; Quintanilha, A.; Figueiredo, A.; et al, 2012. American Journal of Clinical Dermatology. 37 - 47. 1. 13. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84055190900&partnerID=MN8TOARS . 10.2165/11592110-000000000-00000 . American Journal of Clinical Dermatology

Main determinants of PON1 activity in hemodialysis patients.

Ribeiro S; do Sameiro Faria M; Mascarenhas-Melo F; Freitas I; Mendonça MI; Nascimento H; Rocha-Pereira P; et al, 2012. 2012. http://europepmc.org/abstract/med/23007074 . 10.1159/000342235 .

Chemopreventive efficacy of atorvastatin against nitrosamine-induced rat bladder cancer: Antioxidant, anti-proliferative and anti-inflammatory properties

Parada, B.; Reis, F.; Pinto, A.; Sereno, J.; Xavier-Cunha, M.; Neto, P.; Rocha-Pereira, P.; et al, 2012. International Journal of Molecular Sciences. 8482 - 8499. 7. 13. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864363626&partnerID=MN8TOARS . 10.3390/ijms13078482 . International Journal of Molecular Sciences

Expression of Genes Encoding Extracellular Matrix Macromolecules and Metalloproteinases in Avian Tibial Dyschondroplasia

Velada, I.; Capela-Silva, F.; Reis, F.; Pires, E.; Egas, C.; Rodrigues-Santos, P.; Barros, M.T., 2011. Journal of Comparative Pathology. 174 - 186. 2-3. 145. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960233347&partnerID=MN8TOARS . 10.1016/j.jcpa.2010.12.008 . Journal of Comparative Pathology

Health-related quality of life in Portuguese psoriatic patients: Relation with Psoriasis Area and Severity Index and different types of classical psoriatic treatment

Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Carvalho, A.; Figueiredo, A.; Teixeira, F.; et al, 2011. Journal of Dermatology. 816 - 819. 8. 38. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79961043888&partnerID=MN8TOARS . 10.1111/j.1346-8138.2010.01087.x . Journal of Dermatology

Elastase release during the hemodialysis procedure seems to induce changes in red blood cell membrane proteins

Pereira, R.; Rocha, S.; Borges, A.; Nascimento, H.; Reis, F.; Miranda, V.; Sameiro Faria, M.D.; et al, 2011. Hemodialysis International. 429 - 431. 3. 15. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959998735&partnerID=MN8TOARS . 10.1111/j.1542-4758.2011.00554.x . Hemodialysis International

Diabetic nephropathy amelioration by a low-dose sitagliptin in an animal model of type 2 diabetes (Zucker diabetic fatty rat)

Mega, C.; Teixeira De Lemos, E.; Vala, H.; Fernandes, R.; Oliveira, J.; Mascarenhas-Melo, F.; Teixeira, F.; Reis, F., 2011. Experimental Diabetes Research. 2011. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855611505&partnerID=MN8TOARS . 10.1155/2011/162092 . Experimental Diabetes Research

Regular physical exercise training assists in preventing type 2 diabetes development: Focus on its antioxidant and anti-inflammatory properties

Teixeira-Lemos, E.; Nunes, S.; Teixeira, F.; Reis, F., 2011. Cardiovascular Diabetology. 10. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79251551381&partnerID=MN8TOARS . 10.1186/1475-2840-10-12 . Cardiovascular Diabetology

Differential effects of acute (extenuating) and chronic (training) exercise on inflammation and oxidative stress status in an animal model of type 2 diabetes mellitus

Teixeira De Lemos, E.; Pinto, R.; Oliveira, J.; Garrido, P.; Sereno, J.; Mascarenhas-Melo, F.; Páscoa-Pinheiro, J.; Teixeira, F.; Reis, F., 2011. Mediators of Inflammation. 2011. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855165227&partnerID=MN8TOARS . 10.1155/2011/253061 . Mediators of Inflammation

Inhibition of bladder tumour growth by sirolimus in an experimental carcinogenesis model

Parada, B.; Reis, F.; Figueiredo, A.; Nunes, P.; Teixeira-Lemos, E.; Garrido, P.; Sereno, J.; et al, 2011. BJU International. 135 - 143. 1. 107. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650640212&partnerID=MN8TOARS . 10.1111/j.1464-410X.2010.09326.x . BJU International

Apoptosis of peripheral CD4 ++ T-lymphocytes in end-stage renal disease patients under hemodialysis and rhEPO therapies

Borges, A.; Borges, M.; Fernandes, J.; Nascimento, H.; Sameiro-Faria, M.; Miranda, V.; Reis, F.; et al, 2011. Renal Failure. 138 - 143. 2. 33. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952000251&partnerID=MN8TOARS . 10.3109/0886022X.2011.553300 . Renal Failure

Are threshold levels of signal transduction required for the protective effect of cilostazol against cardiac ischaemia-reperfusion injury?

Reis, F., 2011. Clinical and Experimental Pharmacology and Physiology. 651 - 653. 10. 38. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053145905&partnerID=MN8TOARS . 10.1111/j.1440-1681.2011.05564.x . Clinical and Experimental Pharmacology and Physiology

Monoamine oxidase and semicarbazide-sensitive amine oxidase kinetic analysis in mesenteric arteries of patients with type 2 diabetes

Nunes, S.F.; Figueiredo, I.V.; Pereira, J.S.; De Lemos, E.T.; Reis, F.; Teixeira, F.; Caramona, M.M., 2011. Physiological Research. 309 - 315. 2. 60. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959198607&partnerID=MN8TOARS . Physiological Research

Endocannabinoid system in cardiovascular disorders-new pharmacotherapeutic opportunities

Cunha, P.; Romão, A.M.; Mascarenhas-Melo, F.; Teixeira, H.M.; Reis, F., 2011. Journal of Pharmacy and Bioallied Sciences. 350 - 360. 3. 3. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052769788&partnerID=MN8TOARS . 10.4103/0975-7406.84435 . Journal of Pharmacy and Bioallied Sciences

The unsolved cyclosporine-induced kidney injury: Is paricalcitol a feasible new renoprotective option

Reis, F.N.F., 2010. Kidney International. 1055 - 1057. 12. 77. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956930803&partnerID=MN8TOARS . 10.1038/ki.2010.93 . Kidney International

Effect of recombinant human erythropoietin in a rat model of moderate chronic renal failure - focus on inflammation, oxidative stress and function/renoprotection

Garrido, P.; Reis, F.; Costa, E.; Almeida, A.; Parada, B.; Teixeira-Lemos, E.; Santos, P.; et al, 2010. Open Drug Discovery Journal. 25 - 32. SPEC. ISS.. 2. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856868034&partnerID=MN8TOARS . 10.2174/1877381801002020025 . Open Drug Discovery Journal

Effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (ZDF rat)

Reis, F.; Ferreira, L.; Teixeira-De-Lemos, E.; Pinto, F.; Parada, B.; Mega, C.; Vala, H.; et al, 2010. Mediators of Inflammation. 2010. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955406467&partnerID=MN8TOARS . 10.1155/2010/592760 . Mediators of Inflammation

Psoriasis therapy and cardiovascular risk factors: A 12-week follow-up study

Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Rocha, S.; Quintanilha, A.; Figueiredo, A.; et al, 2010. American Journal of Clinical Dermatology. 423 - 432. 6. 11. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78751684955&partnerID=MN8TOARS . 10.2165/11319310-000000000-00000 . American Journal of Clinical Dermatology

Preventive but Not curative efficacy of celecoxib on bladder carcinogenesis in a rat model

Sereno, J.; Parada, B.; Reis, F.; Cunha, F.X.; Teixeira-Lemos, E.; Garrido, P.; Pinto, R.; et al, 2010. Mediators of Inflammation. 2010. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953288402&partnerID=MN8TOARS . 10.1155/2010/380937 . Mediators of Inflammation

Recombinant human erythropoietin treatment protects the cardio-renal axis in a model of moderate chronic renal failure

Teixeira, A.M.; Garrido, P.; Santos, P.; Alves, R.; Parada, B.; Costa, E.; Almeida, A.; et al, 2010. Renal Failure. 1073 - 1080. 9. 32. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957274297&partnerID=MN8TOARS . 10.3109/0886022X.2010.509897 . Renal Failure

C-reactive protein and leucocyte activation in psoriasis vulgaris according to severity and therapy

Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Rocha, S.; Quintanilha, A.; Figueiredo, A.; et al, 2010. Journal of the European Academy of Dermatology and Venereology. 789 - 796. 7. 24. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953197048&partnerID=MN8TOARS . 10.1111/j.1468-3083.2009.03527.x . Journal of the European Academy of Dermatology and Venereology

Interleukin (IL)-22, IL-17, IL-23, IL-8, vascular endothelial growth factor and tumour necrosis factor-a levels in patients with psoriasis before, during and after psoralen-ultraviolet A and narrowband ultraviolet B therapy

Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Rocha, S.; Quintanilha, A.; Figueiredo, A.; et al, 2010. British Journal of Dermatology. 1282 - 1290. 6. 163. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649639288&partnerID=MN8TOARS . 10.1111/j.1365-2133.2010.09992.x . British Journal of Dermatology

Circulating adipokine levels in Portuguese patients with psoriasis vulgaris according to body mass index, severity and therapy

Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Rocha, S.; Quintanilha, A.; Figueiredo, A.; et al, 2010. Journal of the European Academy of Dermatology and Venereology. 1386 - 1394. 12. 24. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78449267411&partnerID=MN8TOARS . 10.1111/j.1468-3083.2010.03647.x . Journal of the European Academy of Dermatology and Venereology

Exercise training decreases proinflammatory profile in Zucker diabetic (type 2) fatty rats

Teixeira de Lemos, E.; Reis, F.; Baptista, S.; Pinto, R.; Sepodes, B.; Vala, H.; Rocha-Pereira, P.; et al, 2009. Nutrition. 330 - 339. 3. 25. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-60349095336&partnerID=MN8TOARS . 10.1016/j.nut.2008.08.014 . Nutrition

Erythropoietin promotes deleterious cardiovascular effects and mortality risk in a rat model of chronic sports doping

Piloto, N.; Teixeira, H.M.; Teixeira-Lemos, E.; Parada, B.; Garrido, P.; Sereno, J.; Pinto, R.; et al, 2009. Cardiovascular Toxicology. 201 - 210. 4. 9. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-71949111878&partnerID=MN8TOARS . 10.1007/s12012-009-9054-2 . Cardiovascular Toxicology

Characterization of a rat model of moderate chronic renal failurefocus on hematological, biochemical, and cardio-renal profiles

Garrido, P.; Reis, F.; Costa, E.; Teixeira-Lemos, E.; Parada, B.; Alves, R.; Piloto, N.; et al, 2009. Renal Failure. 833 - 842. 9. 31. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-71049184825&partnerID=MN8TOARS . 10.3109/08860220903151435 . Renal Failure

Hypertension Induced by Immunosuppressive Drugs: A Comparative Analysis Between Sirolimus and Cyclosporine

Reis, F.; Parada, B.; Teixeira de Lemos, E.; Garrido, P.; Dias, A.; Piloto, N.; Baptista, S.; et al, 2009. Transplantation Proceedings. 868 - 873. 3. 41. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-64649096675&partnerID=MN8TOARS . 10.1016/j.transproceed.2009.02.005 . Transplantation Proceedings

Circulating levels of adiponectin, oxidized LDL and C-reactive protein in Portuguese patients with psoriasis vulgaris, according to body mass index, severity and duration of the disease

Coimbra, S.; Oliveira, H.; Reis, F.; Belo, L.; Rocha, S.; Quintanilha, A.; Figueiredo, A.; et al, 2009. Journal of Dermatological Science. 202 - 204. 3. 55. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67651026846&partnerID=MN8TOARS . 10.1016/j.jdermsci.2009.05.008 . Journal of Dermatological Science

Hepcidin serum levels and resistance to recombinant human erythropoietin therapy in haemodialysis patients

Costa, E.; Swinkels, D.W.; Laarakkers, C.M.; Rocha-Pereira, P.; Rocha, S.; Reis, F.; Teixeira, F.; et al, 2009. Acta Haematologica. 226 - 229. 4. 122. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350521582&partnerID=MN8TOARS . 10.1159/000253590 . Acta Haematologica

Effect of hemodialysis procedure in prohepcidin serum levels in regular hemodialysis patients.

Costa E; Rocha S; Rocha-Pereira P; Reis F; Castro E; Teixeira F; Mir V; et al, 2009. Clinical Nephrology. 233 - 235. 2. 71. 2009. http://europepmc.org/abstract/med/19203525 . Clinical Nephrology

Anti-inflammatory, anti-proliferative and antioxidant profiles of selective cyclooxygenase-2 inhibition as chemoprevention for rat bladder carcinogenesis

Parada, B.; Sereno, J.; Reis, F.; Teixeira-Lemos, E.; Garrido, P.; Pinto, A.F.; Cunha, M.F.; et al, 2009. Cancer Biology and Therapy. 1615 - 1622. 17. 8. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350306703&partnerID=MN8TOARS . 10.4161/cbt.8.17.9199 . Cancer Biology and Therapy

Role of prohepcidin, inflammatory markers and iron status in resistance to rhEPO therapy in hemodialysis patients

Costa, E.; Pereira, B.J.G.; Rocha-Pereira, P.; Rocha, S.; Reis, F.; Castro, E.; Teixeira, F.; et al, 2008. American Journal of Nephrology. 677 - 683. 4. 28. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-45149099284&partnerID=MN8TOARS . 10.1159/000121478 . American Journal of Nephrology

DMT1 (NRAMP2/DCT1) Genetic Variability and Resistance to Recombinant Human Erythropoietin Therapy in Chronic Kidney Disease Patients under Haemodialysis

Costa, E.; Rocha, S.; Rocha-Pereira, P.; Reis, F.; Castro, E.; Teixeira, F.; Miranda, V.; et al, 2008. Acta Haematologica. 11 - 13. 1. 120. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-48049113949&partnerID=MN8TOARS . 10.1159/000149496 . Acta Haematologica

Cross-talk between inflammation, coagulation/fibrinolysis and vascular access in hemodialysis patients

Costa, E.; Rocha, S.; Rocha-Pereira, P.; Castro, E.; Reis, F.; Teixeira, F.; Miranda, V.; et al, 2008. Journal of Vascular Access. 248 - 253. 4. 9. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-60549110919&partnerID=MN8TOARS . Journal of Vascular Access

Treadmill running and swimming imposes distinct cardiovascular physiological adaptations in the rat: Focus on serotonergic and sympathetic nervous systems modulation

Baptista, S.; Piloto, N.; Reis, F.; Teixeira-De-Lemos, E.; Garrido, A.P.; Dias, A.; Lourenço, M.; et al, 2008. Acta Physiologica Hungarica. 365 - 381. 4. 95. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-54949097707&partnerID=MN8TOARS . 10.1556/APhysiol.2008.0002 . Acta Physiologica Hungarica

Dual Effect of Nitrate Therapy for Cyclosporine-Induced Hypertension on Vascular and Platelet Morphofunctional Markers; An Animal Model

Reis, F.; Teixeira de Lemos, E.; Almeida, L.; Parada, B.; Garrido, A.P.; Rocha-Pereira, P.; Santos-Silva, A.; et al, 2007. Transplantation Proceedings. 2501 - 2506. 8. 39. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35348827321&partnerID=MN8TOARS . 10.1016/j.transproceed.2007.07.029 . Transplantation Proceedings

Exercise training is associated with improved levels of C-reactive protein and adiponectin in ZDF (type 2) diabetic rats

De Lemos, E.T.; Reis, F.; Baptista, S.; Pinto, R.; Sepodes, B.; Vala, H.; Rocha-Pereira, P.; Silva, A.S.; Teixeira, F., 2007. Medical Science Monitor. 8. 13. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548396344&partnerID=MN8TOARS . Medical Science Monitor

Oxidative Stress in Cyclosporine-Induced Hypertension: Evidence of Beneficial Effects or Tolerance Development With Nitrate Therapy

Reis, F.; Rocha-Pereira, P.; Teixeira de Lemos, E.; Parada, B.; Baptista, S.; Figueiredo, A.; Santos-Silva, A.; et al, 2007. Transplantation Proceedings. 2494 - 2500. 8. 39. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35348866153&partnerID=MN8TOARS . 10.1016/j.transproceed.2007.07.030 . Transplantation Proceedings

Platelet hyperactivation in maintained growth hormone-deficient childhood patients after therapy withdrawal as a putative earlier marker of increased cardiovascular risk

Reis, F.; Campos, M.V.; Bastos, M.; Almeida, L.; Lourenço, M.; Ferrer-Antunes, C.A.; Palmeiro, A.; et al, 2005. Journal of Clinical Endocrinology and Metabolism. 98 - 105. 1. 90. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-19944427824&partnerID=MN8TOARS . 10.1210/jc.2004-0477 . Journal of Clinical Endocrinology and Metabolism

Effect of preventive and regressive isosorbide 5-mononitrate treatment on catecholamine levels in plasma, platelets, adrenals, left ventricle and aorta in cyclosporin A-induced hypertensive rats

Reis, F.; Rocha, L.; Ponte, L.; Alcobia, T.; Almeida, L.; Costa-Almeida, C.; Teixeira, F., 2005. Life Sciences. 2514 - 2528. 20. 77. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-24044545901&partnerID=MN8TOARS . 10.1016/j.lfs.2005.01.032 . Life Sciences

Curative isosorbide-5-mononitrate treatment, in opposition to the beneficial preventive one, aggravates the prothrombotic and proconstrictor state in cyclosporine-induced hypertensive rats

Reis, F.; Ponte, L.; Rocha, L.; Teixeira-Lemos, E.; Almeida, L.; Alcobia, T.; Lourenço, M.; et al, 2005. Clinical and Experimental Pharmacology and Physiology. 640 - 648. 8. 32. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-22644435282&partnerID=MN8TOARS . 10.1111/j.0305-1870.2005.04244.x . Clinical and Experimental Pharmacology and Physiology

Vitreous humour as a complementary sample to blood for the detection/confirmation of diazepam: ante-mortem and post-mortem studies in an animal model.

Teixeira HM; Reis F; Proença P; Ramos P; Quintela O; López-Rivadulla M; Marques E; Vieira DN, 2004. 2004. http://europepmc.org/abstract/med/15688985 . 10.1191/0960327104ht490oa .

Impairment of vascular and platelet levels of nitric oxide and cyclic guanosine-',5'-monophosphate in cyclosporin A-induced hypertensive rats

Santiago, M.; Reis, F.; Almeida, L.; Alcobia, T.; Dionísio, J.; Teixeira, F., 2003. Fundamental and Clinical Pharmacology. 43 - 50. 1. 17. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037326672&partnerID=MN8TOARS . 10.1046/j.1472-8206.2003.00116.x . Fundamental and Clinical Pharmacology

Isosorbide-5-mononitrate treatment prevents cyclosporin A-induced platelet hyperactivation and the underlying nitric oxide-cyclic guanosine-3', 5'-monophosphate disturbances

Reis, F.; Almeida, L.; Alcobia, T.; Santos-Dias, J.D.; Lourenço, M.; Palmeiro, A.; Ferrer-Antunes, C.A.; et al, 2003. Thrombosis Research. 107 - 115. 2-3. 110. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-10744223826&partnerID=MN8TOARS . 10.1016/S0049-3848(03)00311-6 . Thrombosis Research

Circadian and seasonal variation of endogenous ubiquinone plasma level

Reis, F.; Hermida, R.C.; Souza, I.; Maldonado, J.; Tavares, P.; Fontes-Ribeiro, C.A.; Teixeira, H.M.; et al, 2002. Chronobiology International. 599 - 614. 3. 19. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035989775&partnerID=MN8TOARS . 10.1081/CBI-120004544 . Chronobiology International

Cardiovascular effects of cyclosporin treatment in an experimental model | Efeitos cardiovasculares da ciclosporina num modelo experimental

Tavares, P.; Reis, F.; Fontes Ribeiro, C.A.; Teixeira, F., 2002. Revista Portuguesa de Cardiologia. 141 - 155. 2. 21. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036129786&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Platelet activation is increased in cyclosporin A-induced hypertensive rats

Reis, F.; Tavares, P.; Rito, L.C.; Teixeira, H.M.; Santos Dias, J.D.; Ferrer-Antunes, C.; Mesquita, J.F.; Teixeira, F., 2000. Journal of Cardiovascular Pharmacology. 56 - 64. 1. 36. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033937676&partnerID=MN8TOARS . Journal of Cardiovascular Pharmacology

The distribution of catecholamines between plasma and platelets in cyclosporin A-induced hypertensive rats

Reis, F.; Tavares, P.; Teixeira, F., 2000. Pharmacological Research. 129 - 135. 2. 41. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033839925&partnerID=MN8TOARS . 10.1006/phrs.1999.0572 . Pharmacological Research

The peripheral serotonergic system and platelet aggregation in cyclosporin A-induced hypertensive rats

Reis, F.; Tavares, P.; Ribeiro, C.A.F.; Antunes, F.; Teixeira, F., 1999. Thrombosis Research. 365 - 372. 5. 96. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032762622&partnerID=MN8TOARS . 10.1016/S0049-3848(99)00115-2 . Thrombosis Research